MCID: URT032
MIFTS: 23

Urethra Adenocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Urethra Adenocarcinoma

MalaCards integrated aliases for Urethra Adenocarcinoma:

Name: Urethra Adenocarcinoma 12 15
Adenocarcinoma of the Urethra 12
Urethral Adenocarcinoma 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4910
NCIt 51 C6167
UMLS 74 C1336885

Summaries for Urethra Adenocarcinoma

Disease Ontology : 12 An urethra cancer that derives from epithelial cells of glandular origin.

MalaCards based summary : Urethra Adenocarcinoma, also known as adenocarcinoma of the urethra, is related to clear cell adenocarcinoma and urethra clear cell adenocarcinoma. An important gene associated with Urethra Adenocarcinoma is FNDC3B (Fibronectin Type III Domain Containing 3B), and among its related pathways/superpathways is Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex. The drugs nivolumab and Ipilimumab have been mentioned in the context of this disorder. Related phenotype is homeostasis/metabolism.

Related Diseases for Urethra Adenocarcinoma

Graphical network of the top 20 diseases related to Urethra Adenocarcinoma:



Diseases related to Urethra Adenocarcinoma

Symptoms & Phenotypes for Urethra Adenocarcinoma

MGI Mouse Phenotypes related to Urethra Adenocarcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.23 ALK AMACR APP ARID2 ATM FNDC3B

Drugs & Therapeutics for Urethra Adenocarcinoma

Drugs for Urethra Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
nivolumab Approved Phase 2 946414-94-4
2
Ipilimumab Approved Phase 2 477202-00-9
3 Immunoglobulins Phase 2
4 Antibodies, Monoclonal Phase 2
5 Antineoplastic Agents, Immunological Phase 2
6 Antibodies Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2

Search NIH Clinical Center for Urethra Adenocarcinoma

Genetic Tests for Urethra Adenocarcinoma

Anatomical Context for Urethra Adenocarcinoma

Publications for Urethra Adenocarcinoma

Articles related to Urethra Adenocarcinoma:

# Title Authors Year
1
Female Urethra Adenocarcinoma. ( 29113768 )
2017
2
Adenocarcinoma of the urethra with mucinous features. ( 26029002 )
2015
3
Primary Adenocarcinoma of the Urethra: A Case Report and Review of the Literature. ( 27579397 )
2015
4
Female urethra adenocarcinoma: report of two cases and bibliographic review. ( 25306993 )
2014
5
Primary adenocarcinoma of the urethra with metastasis to the glans penis: successful treatment with chemotherapy and radiation therapy. ( 9730476 )
1998
6
Adenocarcinoma of the urethra in women. A clinicopathologic study. ( 3038294 )
1987
7
Mesonephric adenocarcinoma of the urethra in a woman: report of a case. ( 568184 )
1978
8
Adenocarcinoma of the urethra during pregnancy: report of a case. ( 559986 )
1977

Variations for Urethra Adenocarcinoma

Expression for Urethra Adenocarcinoma

Search GEO for disease gene expression data for Urethra Adenocarcinoma.

Pathways for Urethra Adenocarcinoma

Pathways related to Urethra Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.97 ATM SMAD4

GO Terms for Urethra Adenocarcinoma

Sources for Urethra Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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