MCID: URT032
MIFTS: 25

Urethra Adenocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Urethra Adenocarcinoma

MalaCards integrated aliases for Urethra Adenocarcinoma:

Name: Urethra Adenocarcinoma 12 15
Adenocarcinoma of the Urethra 12
Urethral Adenocarcinoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4910
NCIt 50 C6167
UMLS 73 C1336885

Summaries for Urethra Adenocarcinoma

Disease Ontology : 12 An urethra cancer that derives from epithelial cells of glandular origin.

MalaCards based summary : Urethra Adenocarcinoma, also known as adenocarcinoma of the urethra, is related to urethra clear cell adenocarcinoma and radiation cystitis. An important gene associated with Urethra Adenocarcinoma is FNDC3B (Fibronectin Type III Domain Containing 3B), and among its related pathways/superpathways are Pathways in cancer and Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex. The drugs nivolumab and Antibodies have been mentioned in the context of this disorder. Related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for Urethra Adenocarcinoma

Graphical network of the top 20 diseases related to Urethra Adenocarcinoma:



Diseases related to Urethra Adenocarcinoma

Symptoms & Phenotypes for Urethra Adenocarcinoma

MGI Mouse Phenotypes related to Urethra Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 ALK AMACR APP ARID2 ATM FNDC3B
2 mortality/aging MP:0010768 9.23 ALK AMACR APP ARID2 ATM FNDC3B

Drugs & Therapeutics for Urethra Adenocarcinoma

Drugs for Urethra Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
nivolumab Approved Phase 2 946414-94-4
2 Antibodies Phase 2
3 Immunoglobulins Phase 2
4 Antibodies, Monoclonal Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2

Search NIH Clinical Center for Urethra Adenocarcinoma

Genetic Tests for Urethra Adenocarcinoma

Anatomical Context for Urethra Adenocarcinoma

Publications for Urethra Adenocarcinoma

Articles related to Urethra Adenocarcinoma:

# Title Authors Year
1
Female Urethra Adenocarcinoma. ( 29113768 )
2017
2
Female urethra adenocarcinoma: report of two cases and bibliographic review. ( 25306993 )
2014

Variations for Urethra Adenocarcinoma

Expression for Urethra Adenocarcinoma

Search GEO for disease gene expression data for Urethra Adenocarcinoma.

Pathways for Urethra Adenocarcinoma

Pathways related to Urethra Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.98 ALK KLK3 PAX8 SMAD4
2 9.97 ATM SMAD4

GO Terms for Urethra Adenocarcinoma

Biological processes related to Urethra Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 branching involved in ureteric bud morphogenesis GO:0001658 9.32 PAX8 SMAD4
2 ovarian follicle development GO:0001541 9.26 ATM SMAD4
3 neuron apoptotic process GO:0051402 9.16 APP ATM
4 female gonad development GO:0008585 8.96 ATM SMAD4
5 kidney development GO:0001822 8.8 PAX8 SMAD4 UPK3A

Sources for Urethra Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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