MCID: URT032
MIFTS: 22

Urethra Adenocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Urethra Adenocarcinoma

MalaCards integrated aliases for Urethra Adenocarcinoma:

Name: Urethra Adenocarcinoma 12 15
Adenocarcinoma of the Urethra 12
Urethral Adenocarcinoma 73

Classifications:



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Disease Ontology 12 DOID:4910
NCIt 50 C6167
UMLS 73 C1336885

Summaries for Urethra Adenocarcinoma

Disease Ontology : 12 An urethra cancer that derives from epithelial cells of glandular origin.

MalaCards based summary : Urethra Adenocarcinoma, also known as adenocarcinoma of the urethra, is related to urethra clear cell adenocarcinoma and clear cell adenocarcinoma. An important gene associated with Urethra Adenocarcinoma is FNDC3B (Fibronectin Type III Domain Containing 3B), and among its related pathways/superpathways is Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex. The drugs Nivolumab and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include prostate and thyroid, and related phenotype is homeostasis/metabolism.

Related Diseases for Urethra Adenocarcinoma

Graphical network of the top 20 diseases related to Urethra Adenocarcinoma:



Diseases related to Urethra Adenocarcinoma

Symptoms & Phenotypes for Urethra Adenocarcinoma

MGI Mouse Phenotypes related to Urethra Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.23 ALK AMACR APP ARID2 ATM FNDC3B

Drugs & Therapeutics for Urethra Adenocarcinoma

Drugs for Urethra Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nivolumab Approved Phase 2 946414-94-4
2 Immunoglobulins Phase 2
3 Immunologic Factors Phase 2
4 Antibodies, Monoclonal Phase 2
5 Antibodies Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2

Search NIH Clinical Center for Urethra Adenocarcinoma

Genetic Tests for Urethra Adenocarcinoma

Anatomical Context for Urethra Adenocarcinoma

MalaCards organs/tissues related to Urethra Adenocarcinoma:

41
Prostate, Thyroid

Publications for Urethra Adenocarcinoma

Articles related to Urethra Adenocarcinoma:

# Title Authors Year
1
Female Urethra Adenocarcinoma. ( 29113768 )
2017
2
Adenocarcinoma of the urethra with mucinous features. ( 26029002 )
2015
3
Primary Adenocarcinoma of the Urethra: A Case Report and Review of the Literature. ( 27579397 )
2015
4
Female urethra adenocarcinoma: report of two cases and bibliographic review. ( 25306993 )
2014
5
Cytologic findings of clear cell adenocarcinoma of the urethra: a case report. ( 23110004 )
2012
6
Primary adenocarcinoma of the urethra with metastasis to the glans penis: successful treatment with chemotherapy and radiation therapy. ( 9730476 )
1998
7
Adenocarcinoma of the urethra in women. A clinicopathologic study. ( 3038294 )
1987
8
Mesonephric adenocarcinoma of the urethra in a woman: report of a case. ( 568184 )
1978
9
Adenocarcinoma of the urethra during pregnancy: report of a case. ( 559986 )
1977

Variations for Urethra Adenocarcinoma

Expression for Urethra Adenocarcinoma

Search GEO for disease gene expression data for Urethra Adenocarcinoma.

Pathways for Urethra Adenocarcinoma

Pathways related to Urethra Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.97 ATM SMAD4

GO Terms for Urethra Adenocarcinoma

Sources for Urethra Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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