Urethral Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Urethral Benign Neoplasm

MalaCards integrated aliases for Urethral Benign Neoplasm:

Name: Urethral Benign Neoplasm ¹²

Urethral Neoplasms ⁴⁴ ⁷³

Urethra Cancer ¹² ¹⁵

Malignant Neoplasm of Urethra ⁷³

Malignant Tumour of Urethra ¹²

Malignant Urethral Neoplasm ¹²

Neoplasm of Urethra ¹²

Urethral Carcinoma ⁷³

Neoplasm. Urethra ¹²

Cancer of Urethra ¹²

Urethral Ca ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases Rare diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Neoplasms

Malignant neoplasms of urinary tract

Malignant neoplasm of other and unspecified urinary organs

Malignant neoplasm: Urethra

External Ids:

Disease Ontology ¹² DOID:730 DOID:734

MeSH ⁴⁴ D014523

NCIt ⁵⁰ C3428 C7507 C9106

ICD10 ³³ C68.0

ICD9CM ³⁵ 189.3

SNOMED-CT ⁶⁸ 94123008

UMLS ⁷³ C0041971 C0153620 C0700101

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Summaries for Urethral Benign Neoplasm

Disease Ontology : ¹² An urinary tract cancer that derives from the tissues of the urethra.

MalaCards based summary : Urethral Benign Neoplasm, also known as urethral neoplasms, is related to urethra adenocarcinoma and posterior urethra cancer. An important gene associated with Urethral Benign Neoplasm is FNDC3B (Fibronectin Type III Domain Containing 3B), and among its related pathways/superpathways is Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex. Affiliated tissues include liver, brain and prostate, and related phenotypes are homeostasis/metabolism and mortality/aging

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Related Diseases for Urethral Benign Neoplasm

Diseases in the Urethral Cancer family:

Urethral Benign Neoplasm

Diseases related to Urethral Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)

#	Related Disease	Score	Top Affiliating Genes
1	urethra adenocarcinoma	29.6	ALK AMACR ANKRD28 APP ARID2 ATM
2	posterior urethra cancer	12.1
3	anterior urethra cancer	12.1
4	urethra transitional cell carcinoma	11.0
5	urethral cancer	11.0
6	urethra squamous cell carcinoma	11.0
7	female urethral cancer	10.1	CHGA KLK3
8	small cell carcinoma	10.1	CHGA KLK3
9	endodermal sinus tumor	10.1	CHGA KLK3
10	radiation cystitis	10.1	KLK3 UPK3A
11	gastric cardia carcinoma	10.1	CHGA SMAD4
12	nodular ganglioneuroblastoma	10.1	ALK CHGA
13	acinar cell carcinoma	10.1	CHGA SMAD4
14	telangiectasis	10.0	ATM SMAD4
15	mixed ductal-endocrine carcinoma	10.0	CHGA SMAD4
16	binswanger's disease	10.0	APP CHGA
17	nephrogenic adenoma	10.0	AMACR KLK3
18	prostate small cell carcinoma	10.0	AMACR KLK3
19	prostatic acinar adenocarcinoma	10.0	AMACR KLK3
20	pick disease of brain	9.9	APP CHGA
21	bladder disease	9.9	KLK3 UPK3A
22	autonomic nervous system neoplasm	9.9	ALK APP
23	urethral diverticulum	9.9	AMACR KLK3 UPK3A
24	clear cell adenocarcinoma	9.9	AMACR KLK3 SMAD4
25	prostatic adenoma	9.8
26	adenoma	9.8
27	male reproductive organ cancer	9.8	AMACR CHGA KLK3
28	male reproductive system disease	9.8	AMACR CHGA KLK3
29	peripheral nervous system neoplasm	9.8	ALK APP
30	suppression of tumorigenicity 12	9.6	AMACR CHGA KLK3 SMAD4 UPK3A
31	urethra clear cell adenocarcinoma	8.7	ALK AMACR ANKRD28 APP ARID2 ATM

Comorbidity relations with Urethral Benign Neoplasm via Phenotypic Disease Network (PDN):

Acute Cystitis	Bladder Cancer
Hydronephrosis	Prostate Cancer
Prostatic Hypertrophy

Graphical network of the top 20 diseases related to Urethral Benign Neoplasm:

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Symptoms & Phenotypes for Urethral Benign Neoplasm

MGI Mouse Phenotypes related to Urethral Benign Neoplasm:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	9.61	ALK AMACR APP ARID2 ATM CHGA
2	mortality/aging	MP:0010768	9.23	ALK AMACR APP ARID2 ATM CHGA

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Drugs & Therapeutics for Urethral Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Urethral Benign Neoplasm

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :

pembrolizumab

Cochrane evidence based reviews: urethral neoplasms

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Genetic Tests for Urethral Benign Neoplasm

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Anatomical Context for Urethral Benign Neoplasm

MalaCards organs/tissues related to Urethral Benign Neoplasm:

⁴¹

Liver, Brain, Prostate, Thyroid

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Publications for Urethral Benign Neoplasm

Articles related to Urethral Benign Neoplasm:

#	Title	Authors	Year
1	Primary urethral neoplasms: review of 30 cases. ( 6259375 )	Bolduan JP...Farah RN	1981

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Genes for Urethral Benign Neoplasm

Genes related to Urethral Benign Neoplasm (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	FNDC3B	Fibronectin Type III Domain Containing 3B	Protein Coding	16.06	DISEASES inferred ¹⁵
2	ARID2	AT-Rich Interaction Domain 2	Protein Coding	15.7	DISEASES inferred ¹⁵
3	KLK3	Kallikrein Related Peptidase 3	Protein Coding	14.73	DISEASES inferred ¹⁵
4	UPK3A	Uroplakin 3A	Protein Coding	13.91	DISEASES inferred ¹⁵
5	SMAD4	SMAD Family Member 4	Protein Coding	13.85	DISEASES inferred ¹⁵
6	CHGA	Chromogranin A	Protein Coding	13.69	DISEASES inferred ¹⁵
7	ATM	ATM Serine/Threonine Kinase	Protein Coding	13.47	DISEASES inferred ¹⁵
8	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	13.41	DISEASES inferred ¹⁵
9	APP	Amyloid Beta Precursor Protein	Protein Coding	13.12	DISEASES inferred ¹⁵
10	AMACR	Alpha-Methylacyl-CoA Racemase	Protein Coding	13.05	DISEASES inferred ¹⁵
11	ANKRD28	Ankyrin Repeat Domain 28	Protein Coding	7	DISEASES inferred ¹⁵

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Variations for Urethral Benign Neoplasm

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Expression for Urethral Benign Neoplasm

Search GEO for disease gene expression data for Urethral Benign Neoplasm.

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Pathways for Urethral Benign Neoplasm

Pathways related to Urethral Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex ¹	9.97	ATM SMAD4

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GO Terms for Urethral Benign Neoplasm

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Urethral Benign Neoplasm

Aliases & Classifications for Urethral Benign Neoplasm

MalaCards integrated aliases for Urethral Benign Neoplasm:

Classifications:

External Ids:

Summaries for Urethral Benign Neoplasm

Related Diseases for Urethral Benign Neoplasm

Diseases in the Urethral Cancer family:

Diseases related to Urethral Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

Comorbidity relations with Urethral Benign Neoplasm via Phenotypic Disease Network (PDN):

Graphical network of the top 20 diseases related to Urethral Benign Neoplasm:

Symptoms & Phenotypes for Urethral Benign Neoplasm

MGI Mouse Phenotypes related to Urethral Benign Neoplasm:

Drugs & Therapeutics for Urethral Benign Neoplasm

Inferred drug relations via UMLS 73 / NDF-RT 51 :

Cochrane evidence based reviews: urethral neoplasms

Genetic Tests for Urethral Benign Neoplasm

Anatomical Context for Urethral Benign Neoplasm

MalaCards organs/tissues related to Urethral Benign Neoplasm:

Publications for Urethral Benign Neoplasm

Articles related to Urethral Benign Neoplasm:

Genes for Urethral Benign Neoplasm

Genes related to Urethral Benign Neoplasm (0 elite genes):

Variations for Urethral Benign Neoplasm

Expression for Urethral Benign Neoplasm

Pathways for Urethral Benign Neoplasm

Pathways related to Urethral Benign Neoplasm according to GeneCards Suite gene sharing:

GO Terms for Urethral Benign Neoplasm

Sources for Urethral Benign Neoplasm

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :