MCID: URT011
MIFTS: 25

Urethral Calculus

Categories: Nephrological diseases

Aliases & Classifications for Urethral Calculus

MalaCards integrated aliases for Urethral Calculus:

Name: Urethral Calculus 12 15
Calculus in Urethra 70 32
Urethral Stone 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9589
ICD9CM 34 594.2
NCIt 50 C26995
SNOMED-CT 67 20342001
ICD10 32 N21.1
UMLS 70 C0162301

Summaries for Urethral Calculus

MalaCards based summary : Urethral Calculus, also known as calculus in urethra, is related to urethral stricture and urethral diverticulum. An important gene associated with Urethral Calculus is PPCS (Phosphopantothenoylcysteine Synthetase), and among its related pathways/superpathways is Glyoxylate and dicarboxylate metabolism. Affiliated tissues include kidney and pancreas.

Wikipedia : 73 Kidney stone disease, also known as nephrolithiasis or urolithiasis, is when a solid piece of material... more...

Related Diseases for Urethral Calculus

Diseases related to Urethral Calculus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 urethral stricture 30.2 MCU KLK3
2 urethral diverticulum 29.7 PPCS MCU KLK3
3 urolithiasis 10.2
4 bladder calculus 10.0 PPCS KLK3
5 adenine phosphoribosyltransferase deficiency 10.0 HOGA1 GRHPR
6 hyperoxaluria, primary, type iii 10.0 HOGA1 GRHPR
7 xanthinuria 10.0 HOGA1 GRHPR
8 nephrolithiasis, uric acid 10.0 HOGA1 GRHPR
9 dent disease 1 9.9 HOGA1 GRHPR
10 ureterocele 9.9
11 cryptorchidism, unilateral or bilateral 9.9
12 gastroschisis 9.9
13 prostatic hyperplasia, benign 9.9
14 urinary tract infection 9.9
15 osteomyelitis 9.9
16 hypospadias 9.9
17 prostatic hypertrophy 9.9
18 neurogenic bladder 9.9
19 prostatic adenoma 9.9
20 anuria 9.9
21 urinary tract obstruction 9.9
22 nephrolithiasis 9.9
23 abdominal wall defect 9.9
24 carbohydrate metabolic disorder 9.9 HOGA1 GRHPR
25 hydronephrosis 9.9
26 pyelonephritis 9.9
27 penile cancer 9.9
28 balanitis 9.9
29 urethritis 9.9
30 balanitis xerotica obliterans 9.9
31 leukoplakia of penis 9.9
32 urethral gland abscess 9.9
33 malignant tumor of penis 9.9
34 lower urinary tract calculus 9.9 MCU KLK3
35 cystinuria 9.9 HOGA1 GRHPR
36 urethral syndrome 9.8 MCU KLK3
37 primary hyperoxaluria 9.8 HOGA1 GRHPR

Comorbidity relations with Urethral Calculus via Phenotypic Disease Network (PDN):


Acute Cystitis Bladder Neck Obstruction
Hydronephrosis Nephrolithiasis, X-Linked Recessive, with Renal Failure
Prostate Cancer Prostatic Hypertrophy
Ureterolithiasis Urethral Stricture

Graphical network of the top 20 diseases related to Urethral Calculus:



Diseases related to Urethral Calculus

Symptoms & Phenotypes for Urethral Calculus

Drugs & Therapeutics for Urethral Calculus

Search Clinical Trials , NIH Clinical Center for Urethral Calculus

Genetic Tests for Urethral Calculus

Anatomical Context for Urethral Calculus

MalaCards organs/tissues related to Urethral Calculus:

40
Kidney, Pancreas

Publications for Urethral Calculus

Articles related to Urethral Calculus:

(show top 50) (show all 118)
# Title Authors PMID Year
1
Ultrasonography and Surgical Treatment of an Unusual Case of Urethral Calculus in an Arabian Horse. 61
32797778 2020
2
Extra-abdominal Cryptorchidism Associated With Gastroschisis and Impacted Urethral Calculus: Two Uncommon Urologic Conditions in One Patient. 61
32320791 2020
3
Urethral Calculi. 61
32426654 2020
4
Formation of a calcium oxalate urethral stone in a 3-year-old boy due to hypocitraturia. 61
32743468 2020
5
Giant urethral calculus in anterior urethral diverticulum: a case report. 61
31357972 2019
6
Flap Combination Phalloplasty in Female-to-Male Transsexuals. 61
30894300 2019
7
Urethral calculi: A rare cause of acute urinary retention in women. 61
30533562 2018
8
Large anterior urethral calculus masquerading as periurethral abscess. 61
30413442 2018
9
Posterior urethral valve presenting with impacted prostatic urethral calculus: a diagnostic challenge. 61
30206058 2018
10
Giant Urethral Calculus without Acute Urinary Retention. 61
29482714 2018
11
Urethral calculi with a urethral fistula: a case report and review of the literature. 61
28874183 2017
12
Bilateral Single System Orthotopic Ureterocele with Bilateral Multiple Calculi Presented with Retention of Urine - an Urological Emergency. 61
28892967 2017
13
Extending indications of micropercutaneous nephrolithotomy: It is not just about cracking stones. 61
28275513 2017
14
Anastomotic Urethroplasty for an Obstructing Calculus Within a Bulbar Urethral Diverticulum and Urethral Stricture. 61
27981035 2017
15
Giant anterior urethral calculus associated with urethrocutaneous fistula in an elderly man. 61
27671903 2016
16
Iatrogenic watering-can perineum and osteomyelitis of pubic ramus as a complication of post-urethral calculus removal UTI. 61
30364425 2016
17
Urethral calculus originating from ureterocele and causing urinary retention. 61
26498566 2015
18
Iliac Vein Compression Syndrome due to Bladder Distention Caused by Urethral Calculi. 61
25802794 2015
19
Rapid evaluation of urinary retention and penile pain using point-of-care ultrasound. 61
25098806 2014
20
A Giant Urethral Calculus. 61
26982670 2014
21
Acute urinary retention in women due to urethral calculi: A rare case. 61
24554984 2014
22
Large anterior urethral calculus presented as scrotal mass with urethrocutaneous fistula. 61
24068377 2013
23
Impacted anterior urethral calculus complicated by a stone-containing diverticulum in an elderly man: outcome of transurethral lithotripsy without resection of the diverticulum. 61
24267119 2013
24
Rise in emergency department visits of pediatric patients for renal colic from 1999 to 2008. 61
23528508 2013
25
A giant dumbbell shaped vesico-prostatic urethral calculus: a case report and review of literature. 61
23762742 2013
26
Obstructing urethral calculus in a woman revealed to be the cause of chronic pelvic pain. 61
22407234 2012
27
Xanthogranulomatous pyelonephritis in a male child--a case report with a brief review of literature. 61
23738410 2012
28
Urethral calculus. 61
19939603 2012
29
Giant urethral diverticulum calculus presenting as scrotal abscess. 61
22302916 2012
30
[A case of prostatic urethral calculus associated with perineal abscess and urethrocutaneous fistula]. 61
22343742 2012
31
Giant urethral calculus. 61
24950400 2011
32
Unusual giant prostatic urethral calculus. 61
22091328 2010
33
Impacted urethral calculus discovered on pelvic ultrasound: a case report. 61
19947057 2009
34
Acute urinary retention secondary to a urethral calculus in a bladder-drained kidney pancreas transplant patient - a metallic clip nidus. 61
19215698 2009
35
Giant urethral calculus in a 6-year-old girl. 61
19013415 2008
36
Evaluation of patients with suspected ureteral calculi using sonography as an initial diagnostic tool: how can we improve diagnostic accuracy? 61
18809954 2008
37
Combined urethrolithotomy with vesicolithotomy in an 18-months old boy. 61
19385479 2008
38
[Laser hair removal for urethral hair after hypospadias repair]. 61
18260346 2008
39
Management of urethral calculi associated with hairballs after urethroplasty for severe hypospadias. 61
17302576 2007
40
Transrectal voiding sonourethrography for diagnosis of a prostatic urethral calculus. 61
17060434 2006
41
Giant prostatic urethral calculus associated with urethrocutaneous fistula. 61
16771746 2006
42
Outcomes of urethral calculi patients in an endemic region and an undiagnosed primary fossa navicularis calculus. 61
16432690 2006
43
Giant calculus of the posterior urethra following recurrent penile urethral stricture. 61
12187051 2002
44
Laser lithotripsy of a urethral calculus via ischial urethrotomy in a steer. 61
11549094 2001
45
[Multiple urethral lithiasis. Report of a case]. 61
10900774 2000
46
Urethral calculus extraction using a penile ring block anesthetic. 61
9800901 1998
47
Pulsed dye laser lithotripsy for treatment of urolithiasis in two geldings. 61
9604033 1998
48
Giant urethral calculus: a rare cause of acute urinary retention. 61
8969990 1996
49
INTRACARDIAC TUMOURS - EXPERIENCE WITH 12 CASES. 61
28769371 1996
50
Intracorporeal lithotripsy with the Swiss lithoclast. 61
7827836 1994

Variations for Urethral Calculus

Expression for Urethral Calculus

Search GEO for disease gene expression data for Urethral Calculus.

Pathways for Urethral Calculus

Pathways related to Urethral Calculus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.1 HOGA1 GRHPR

GO Terms for Urethral Calculus

Biological processes related to Urethral Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glyoxylate metabolic process GO:0046487 8.62 HOGA1 GRHPR

Molecular functions related to Urethral Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 8.8 PPCS HOGA1 GRHPR

Sources for Urethral Calculus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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