Aliases & Classifications for Urethral Calculus

MalaCards integrated aliases for Urethral Calculus:

Name: Urethral Calculus 12 15
Calculus in Urethra 73
Urethral Stone 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9589
ICD10 33 N21.1
ICD9CM 35 594.2
NCIt 50 C26995
SNOMED-CT 68 155880008 20342001
UMLS 73 C0162301

Summaries for Urethral Calculus

MalaCards based summary : Urethral Calculus, also known as calculus in urethra, is related to urethritis and prostatitis. An important gene associated with Urethral Calculus is PLIN1 (Perilipin 1), and among its related pathways/superpathways are Ca, cAMP and Lipid Signaling and Androgen receptor signaling pathway. Affiliated tissues include kidney, prostate and pancreas, and related phenotype is behavior/neurological.

Wikipedia : 76 Kidney stone disease, also known as urolithiasis, is when a solid piece of material (kidney stone)... more...

Related Diseases for Urethral Calculus

Diseases related to Urethral Calculus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 urethritis 10.7
2 prostatitis 10.2
3 ureterocele 9.8
4 aging 9.8
5 nephrolithiasis 9.8
6 hypospadias 9.8
7 leech infestation 9.8 F2 FLNA
8 leukoplakia of penis 9.8
9 taylor's syndrome 9.7 F2 FLNA
10 paraphimosis 9.6 FLNA KLK3
11 urethral diverticulum 9.4 KLK3 MCU
12 suprasellar meningioma 9.4 F2 KLK3
13 acute cystitis 9.3 KLK3 MCU
14 migraine with aura 9.2 F2 FLNA
15 bladder disease 9.2 KLK3 MCU
16 lower urinary tract calculus 8.2 F2 FLNA MCU PLIN1 USF1

Comorbidity relations with Urethral Calculus via Phenotypic Disease Network (PDN):


Acute Cystitis Bladder Neck Obstruction
Hydronephrosis Nephrolithiasis, X-Linked Recessive, with Renal Failure
Prostate Cancer Prostatic Hypertrophy
Ureterolithiasis Urethral Stricture

Graphical network of the top 20 diseases related to Urethral Calculus:



Diseases related to Urethral Calculus

Symptoms & Phenotypes for Urethral Calculus

MGI Mouse Phenotypes related to Urethral Calculus:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.02 F2 FLNA MCU PLIN1 USF1

Drugs & Therapeutics for Urethral Calculus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Shock Wave Lithotripsy Versus Visual Cystolitholapaxy in The Management of Patients Presenting With Calcular Acute Urinary Retention: A Randomized Controlled Trial. Unknown status NCT02594631 Phase 4
2 Conditional Imaging Prescription Strategy for Exploration of Acute Uncomplicated Renal Colic Completed NCT02878148 Not Applicable

Search NIH Clinical Center for Urethral Calculus

Genetic Tests for Urethral Calculus

Anatomical Context for Urethral Calculus

MalaCards organs/tissues related to Urethral Calculus:

41
Kidney, Prostate, Pancreas

Publications for Urethral Calculus

Articles related to Urethral Calculus:

(show top 50) (show all 58)
# Title Authors Year
1
Giant Urethral Calculus without Acute Urinary Retention. ( 29482714 )
2018
2
Giant anterior urethral calculus associated with urethrocutaneous fistula in an elderly man. ( 27671903 )
2016
3
Urethral calculus originating from ureterocele and causing urinary retention. ( 26498566 )
2015
4
A Giant Urethral Calculus. ( 26982670 )
2014
5
Large anterior urethral calculus presented as scrotal mass with urethrocutaneous fistula. ( 24068377 )
2013
6
A giant dumbbell shaped vesico-prostatic urethral calculus: a case report and review of literature. ( 23762742 )
2013
7
Impacted anterior urethral calculus complicated by a stone-containing diverticulum in an elderly man: outcome of transurethral lithotripsy without resection of the diverticulum. ( 24267119 )
2013
8
Obstructing urethral calculus in a woman revealed to be the cause of chronic pelvic pain. ( 22407234 )
2012
9
Urethral calculus. ( 19939603 )
2012
10
Giant urethral calculus. ( 24950400 )
2011
11
Unusual giant prostatic urethral calculus. ( 22091328 )
2010
12
Impacted urethral calculus discovered on pelvic ultrasound: a case report. ( 19947057 )
2009
13
Acute urinary retention secondary to a urethral calculus in a bladder-drained kidney pancreas transplant patient - a metallic clip nidus. ( 19215698 )
2009
14
Giant urethral calculus in a 6-year-old girl. ( 19013415 )
2008
15
Transrectal voiding sonourethrography for diagnosis of a prostatic urethral calculus. ( 17060434 )
2006
16
Giant prostatic urethral calculus associated with urethrocutaneous fistula. ( 16771746 )
2006
17
Laser lithotripsy of a urethral calculus via ischial urethrotomy in a steer. ( 11549094 )
2001
18
Urethral calculus extraction using a penile ring block anesthetic. ( 9800901 )
1998
19
Giant urethral calculus: a rare cause of acute urinary retention. ( 8969990 )
1996
20
Giant urethral calculus. ( 7899907 )
1994
21
Formation of a urethral calculus around an unusual foreign body. ( 8402033 )
1993
22
Use of transperineal sonography to locate an obstructing urethral calculus. ( 8416631 )
1993
23
Pediatric bladder outlet obstruction due to urethral calculus. Case report and review of the literature. ( 8309762 )
1993
24
Struvite urethral calculus in a three-month-old thoroughbred colt. ( 1643877 )
1992
25
Giant posterior urethral calculus. ( 2337755 )
1990
26
Re: Giant posterior urethral calculus. A. Bolukbasi and B. Gumus. Br. J. Urol., 65, 301-302, 1990. ( 2249137 )
1990
27
Expulsion of urethral calculus following intermittent closure of suprapubic catheter. ( 2804575 )
1989
28
Giant urethral calculus. ( 2611634 )
1989
29
Sonographic diagnosis of an obstructing urethral calculus. ( 3054147 )
1988
30
Spontaneous passage of large urethral calculus. ( 3942026 )
1986
31
Foreign body urethral calculus 9 years after traumatic perforation of the rectum. ( 4005511 )
1985
32
Giant anterior urethral calculus associated with hypospadias and congenital meatal stenosis. ( 3971094 )
1985
33
Giant urethral calculus in a nine-year-old girl. ( 3971095 )
1985
34
Ultrasonic detection of urethral calculus. ( 3904910 )
1985
35
Impacted membranous urethral calculus. ( 6520412 )
1984
36
Spontaneous delivery of giant urethral calculus. ( 6674358 )
1983
37
Giant prostatic urethral calculus. (A case report). ( 6864581 )
1983
38
Submucosal urethral calculus secondary to foxtail awn migration in a dog. ( 6345496 )
1983
39
Case profile: radiolucent urethral calculus with hemostatic clip nidus. ( 7064268 )
1982
40
Giant urethral calculus: a case report. ( 561198 )
1977
41
Giant urethral calculus: a case report. ( 940221 )
1976
42
Prostatic urethral calculus. ( 5016075 )
1972
43
Urethral calculus in a six-week-old puppy. ( 6070657 )
1967
44
Impacted urethral calculus. An analysis of 42 cases. ( 5945414 )
1966
45
Surgical management of an unusual urethral calculus. ( 13980456 )
1963
46
Impacted vesico-urethral calculus: a case report. ( 13900169 )
1961
47
Giant urethral calculus: a case report. ( 13564579 )
1958
48
Urethral calculus: its roentgen evaluation. ( 13134511 )
1954
49
Urethral calculus in the male, with particular reference to giant primary stones. ( 15399440 )
1950
50
Large urethral calculus; case report. ( 18141445 )
1949

Variations for Urethral Calculus

Expression for Urethral Calculus

Search GEO for disease gene expression data for Urethral Calculus.

Pathways for Urethral Calculus

Pathways related to Urethral Calculus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.26 MCU PLIN1
2 10.91 FLNA KLK3
3 9.95 F2 KLK3

GO Terms for Urethral Calculus

Biological processes related to Urethral Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet activation GO:0030168 9.16 F2 FLNA
2 glucose homeostasis GO:0042593 8.96 MCU USF1
3 negative regulation of fibrinolysis GO:0051918 8.62 F2 USF1

Molecular functions related to Urethral Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type peptidase activity GO:0008236 8.62 F2 KLK3

Sources for Urethral Calculus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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