MCID: URT011
MIFTS: 29

Urethral Calculus

Categories: Nephrological diseases
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Aliases & Classifications for Urethral Calculus

MalaCards integrated aliases for Urethral Calculus:

Name: Urethral Calculus 11 14 75 33
Calculus in Urethra 71 31 33
Urethral Stone 11 33
Urethral Calculus Impaction 33
Urethra Calculus Impaction 33
Urethral Calculi Impaction 33
Urethra Calculi Impaction 33
Calculous Urethritis 33
Urethrolithiasis 33
Urethra Stone 33

Classifications:



External Ids:

Disease Ontology 11 DOID:9589
ICD9CM 34 594.2
NCIt 49 C26995
SNOMED-CT 68 20342001
ICD10 31 N21.1
ICD11 33 1853962389
UMLS 71 C0162301

Summaries for Urethral Calculus

MalaCards based summary: Urethral Calculus, also known as calculus in urethra, is related to urinary tract infection and nephrolithiasis, calcium oxalate. An important gene associated with Urethral Calculus is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways are Glyoxylate metabolism and glycine degradation and 4-hydroxyproline degradation. Affiliated tissues include kidney, prostate and pancreas.

Wikipedia: 75 Kidney stone disease, also known as nephrolithiasis or urolithiasis, is a crystallopathy where a solid... more...

Related Diseases for Urethral Calculus

Diseases related to Urethral Calculus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 urinary tract infection 29.9 KLK3 HOGA1
2 nephrolithiasis, calcium oxalate 10.3
3 urethral stricture 10.3
4 urolithiasis 10.2
5 bladder neck obstruction 10.1
6 urethral diverticulum 10.1
7 posterior urethral valves 10.1
8 ureterolithiasis 10.0 KLK3 GRHPR
9 bladder tuberculosis 10.0 PPCS KLK3
10 hyperoxaluria, primary, type ii 10.0 HOGA1 GRHPR
11 hyperoxaluria, primary, type iii 10.0 HOGA1 GRHPR
12 adenine phosphoribosyltransferase deficiency 10.0 HOGA1 GRHPR
13 purine-pyrimidine metabolic disorder 10.0 HOGA1 GRHPR
14 ureterocele 9.9
15 cryptorchidism, unilateral or bilateral 9.9
16 gastroschisis 9.9
17 prostatic hyperplasia, benign 9.9
18 osteomyelitis 9.9
19 hypospadias 9.9
20 neurogenic bladder 9.9
21 cystitis 9.9
22 anuria 9.9
23 urinary tract obstruction 9.9
24 nephrolithiasis 9.9
25 xanthinuria 9.9 HOGA1 GRHPR
26 glycogen storage disease v 9.9
27 uremia 9.9
28 peritonitis 9.9
29 lichen sclerosus et atrophicus 9.9
30 stroke, ischemic 9.9
31 hydronephrosis 9.9
32 bladder calculus 9.9
33 pyelonephritis 9.9
34 penile cancer 9.9
35 penile benign neoplasm 9.9
36 balanitis 9.9
37 urethritis 9.9
38 balanitis xerotica obliterans 9.9
39 kidney disease 9.9
40 urethral gland abscess 9.9
41 fournier gangrene 9.9
42 malignant tumor of penis 9.9
43 cystinuria 9.8 HOGA1 GRHPR
44 primary hyperoxaluria 9.7 HOGA1 GRHPR

Comorbidity relations with Urethral Calculus via Phenotypic Disease Network (PDN):


Acute Cystitis Bladder Neck Obstruction
Hydronephrosis Nephrolithiasis, X-Linked Recessive, with Renal Failure
Prostate Cancer Prostatic Hypertrophy
Ureterolithiasis Urethral Stricture

Graphical network of the top 20 diseases related to Urethral Calculus:



Diseases related to Urethral Calculus

Symptoms & Phenotypes for Urethral Calculus

Drugs & Therapeutics for Urethral Calculus

Search Clinical Trials, NIH Clinical Center for Urethral Calculus

Genetic Tests for Urethral Calculus

Anatomical Context for Urethral Calculus

Organs/tissues related to Urethral Calculus:

MalaCards : Kidney, Prostate, Pancreas

Publications for Urethral Calculus

Articles related to Urethral Calculus:

(show top 50) (show all 209)
# Title Authors PMID Year
1
Single-stage noninvasive antegrade endoscopic treatment of large bladder and urethral stone: A case report. 62
36369125 2022
2
Prostatic urethral calculus after water vapour thermal therapy of the prostate. 62
35041237 2022
3
A randomised trial comparing transurethral to percutaneous cystolithotripsy in boys. 62
35044035 2022
4
Male Urethral Diverticulum with Stones Presenting as Acute Urinary Retention. 62
36210691 2022
5
Ureteropyeloscopic removal of a nephrolith from a 19 year old Hanoverian gelding. 62
35535970 2022
6
Encrusted cystitis and ascites due to urethral calculus. 62
35509476 2022
7
Debilitating complications of unsuspected urethral stone: Case report and literature review. 62
35070721 2022
8
Impacted urethral stone presenting as urinary retention in a child. 62
33495172 2021
9
Single-stage Simultaneous Retrograde and Antegrade Endoscopic Treatment of Giant Prostatic and Bladder Urethral Calculi. 62
32717249 2020
10
Ultrasonography and Surgical Treatment of an Unusual Case of Urethral Calculus in an Arabian Horse. 62
32797778 2020
11
Extra-abdominal Cryptorchidism Associated With Gastroschisis and Impacted Urethral Calculus: Two Uncommon Urologic Conditions in One Patient. 62
32320791 2020
12
Large urethral stone impersonating as penile cancer. 62
32816939 2020
13
Use of percutaneous transvenous coil embolization in the treatment of intrahepatic portosystemic shunts in four cats. 62
32538708 2020
14
Urethral Calculi. 62
32426654 2020
15
Formation of a calcium oxalate urethral stone in a 3-year-old boy due to hypocitraturia. 62
32743468 2020
16
Effects of Isothermic Irrigation on Core Body Temperature During Endoscopic Urethral Stone Treatment Surgery Under Spinal Anesthesia: A Randomized Controlled Trial. 62
30882163 2020
17
[Urethrolithiasis in the dog - a retrospective evaluation of 83 male dogs]. 62
31814087 2019
18
Diagnosis and management of a remnant of the original fistula (ROOF) in males following surgery for anorectal malformations. 62
30879755 2019
19
Evaluation of the clinical significance of sonographic perinephric fluid in patients with renal colic. 62
30595428 2019
20
Giant urethral calculus in anterior urethral diverticulum: a case report. 62
31357972 2019
21
Brachytherapy seeds as a nidus for urethral stone formation: A case report. 62
32743414 2019
22
Flap Combination Phalloplasty in Female-to-Male Transsexuals. 62
30894300 2019
23
Successful Distal Urethral Stone Removal in the Emergency Department. 62
30700384 2019
24
[Management of urethral stones in dogs using pneumatic and laser lithotripsy]. 62
31013525 2019
25
Urethral calculi: A rare cause of acute urinary retention in women. 62
30533562 2018
26
Large anterior urethral calculus masquerading as periurethral abscess. 62
30413442 2018
27
Posterior urethral valve presenting with impacted prostatic urethral calculus: a diagnostic challenge. 62
30206058 2018
28
Voluminous Urethral Stone - A Very Rare Complication After Male Suburethral Sling Surgery As A Result of Sling Erosion Into Proximal Urethra. 62
29681051 2018
29
Giant Urethral Calculus without Acute Urinary Retention. 62
29482714 2018
30
Unexpected Detection of Urethral Stone on 18F-NaF PET/CT. 62
29215414 2018
31
Use of percutaneous cystolithotomy for removal of urethral uroliths in a pot-bellied pig. 62
29386676 2018
32
The Benefits of Using a Small Caliber Ureteroscope in Evaluation and Management of Urethral Stricture. 62
30584423 2018
33
Supine Ultrasound-guided Percutaneous Nephrolithotomy with Retrograde Semi-rigid Ureteroscopic guidwire retrieval: Description of an Evolved Technique. 62
29101757 2017
34
Urethral calculi with a urethral fistula: a case report and review of the literature. 62
28874183 2017
35
Bilateral Single System Orthotopic Ureterocele with Bilateral Multiple Calculi Presented with Retention of Urine - an Urological Emergency. 62
28892967 2017
36
[Spontaneous renal rupture of fornix due to obstructing urethral stone]. 62
28606297 2017
37
Extending indications of micropercutaneous nephrolithotomy: It is not just about cracking stones. 62
28275513 2017
38
Facilitate Stent Removal: Magnetic DJ Stent. 62
28180089 2017
39
A Giant Female Urethral Stone: An Unusual Complication after MidUrethral Sling Operation. 62
26393785 2017
40
Anastomotic Urethroplasty for an Obstructing Calculus Within a Bulbar Urethral Diverticulum and Urethral Stricture. 62
27981035 2017
41
Giant anterior urethral calculus associated with urethrocutaneous fistula in an elderly man. 62
27671903 2016
42
Male urethral diverticulum uncommon entity: Our experience. 62
28057997 2016
43
Urethral stone of unexpected size: case report and short literature review. 62
28352758 2016
44
Iatrogenic watering-can perineum and osteomyelitis of pubic ramus as a complication of post-urethral calculus removal UTI. 62
30364425 2016
45
Urethroscrotal Fistula: A Rare Cause of Scrotal Swelling. 62
27668028 2016
46
Urethral calculus originating from ureterocele and causing urinary retention. 62
26498566 2015
47
Urethral Calculi in a 7-Year-old Boy Presenting as a Large Scrotal Mass After Surgery of Exstrophy-epispadias Repair. 62
26199152 2015
48
Iliac Vein Compression Syndrome due to Bladder Distention Caused by Urethral Calculi. 62
25802794 2015
49
Rapid evaluation of urinary retention and penile pain using point-of-care ultrasound. 62
25098806 2014
50
A Giant Urethral Calculus. 62
26982670 2014

Variations for Urethral Calculus

Expression for Urethral Calculus

Search GEO for disease gene expression data for Urethral Calculus.

Pathways for Urethral Calculus

Pathways related to Urethral Calculus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.54 HOGA1 GRHPR
2
Show member pathways
10.02 HOGA1 GRHPR

GO Terms for Urethral Calculus

Biological processes related to Urethral Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glyoxylate metabolic process GO:0046487 8.92 HOGA1 GRHPR

Sources for Urethral Calculus

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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