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MCID: URT016
MIFTS: 30

Urethral Diverticulum

Categories: Nephrological diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Urethral Diverticulum

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MalaCards integrated aliases for Urethral Diverticulum:

Name: Urethral Diverticulum 12 15 71 32

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:9341
ICD9CM 34 599.2
NCIt 49 C39861
SNOMED-CT 67 90531003
ICD10 32 N36.1
UMLS 71 C0152443
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Summaries for Urethral Diverticulum

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MalaCards based summary : Urethral Diverticulum is related to acute cystitis and chronic cystitis. An important gene associated with Urethral Diverticulum is MCU (Mitochondrial Calcium Uniporter). The drugs Prednisolone and Methylprednisolone hemisuccinate have been mentioned in the context of this disorder. Affiliated tissues include prostate, kidney and spinal cord.

Wikipedia : 74 A urethral diverticulum is a condition where the urethra or the periurethral glands push into the... more...

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Related Diseases for Urethral Diverticulum

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Diseases related to Urethral Diverticulum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 acute cystitis 30.5 UPK3A MCU KLK3
2 chronic cystitis 30.3 UPK3A KRT7
3 urethral calculus 30.2 MCU KLK3
4 ureterocele 30.2 PAX8 MCU
5 mucinous adenocarcinoma 29.9 KRT7 AMACR
6 urethral stricture 29.9 MCU LINC00538 KLK3 BCL2L10
7 hydronephrosis 29.8 UPK3A MCU KRT7
8 transitional cell carcinoma 29.8 UPK3A KRT7 KLK3
9 prostatic cyst 29.8 KLK3 BCL2L10
10 urethral syndrome 29.5 MCU KLK3
11 clear cell adenocarcinoma 29.5 PAX8 KRT7 KLK3 AMACR
12 urinary tract obstruction 29.5 UPK3A KLK3
13 nephrogenic adenoma 29.4 PAX8 KRT7 KLK3 AMACR
14 cystadenoma 29.3 KRT7 KLK3
15 female urethral cancer 29.2 KRT7 KLK3 AMACR
16 suppression of tumorigenicity 12 29.0 KRT7 KLK3 AMACR
17 adenocarcinoma 10.6
18 adenoma 10.5
19 cystitis 10.4
20 hypospadias 10.4
21 squamous cell carcinoma 10.2
22 urethral cancer 10.2
23 spinal cord injury 10.2
24 renal pelvis transitional cell carcinoma 10.2 UPK3A KRT7
25 vulval paget's disease 10.2 UPK3A KRT7
26 vulva adenocarcinoma 10.2 UPK3A KRT7
27 transitional papilloma 10.2 UPK3A KRT7
28 papillary transitional carcinoma 10.2 UPK3A KRT7
29 ovarian brenner tumor 10.2 UPK3A KRT7
30 ureteral benign neoplasm 10.2 UPK3A KRT7
31 endometriosis 10.2
32 paraplegia 10.2
33 in situ carcinoma 10.2
34 47,xyy 10.2
35 ureteral disease 10.2 UPK3A MCU
36 ovarian mesodermal adenosarcoma 10.1 PAX8 KRT7
37 rete testis neoplasm 10.1 PAX8 KRT7
38 rete testis adenocarcinoma 10.1 PAX8 KRT7
39 ovarian seromucinous carcinoma 10.1 PAX8 KRT7
40 renal pelvis adenocarcinoma 10.1 PAX8 KRT7
41 ovarian wilms' cancer 10.1 PAX8 KRT7
42 clear cell papillary renal cell carcinoma 10.1 KRT7 AMACR
43 leiomyoma 10.1
44 pyuria 10.1
45 impotence 10.1
46 vaginal discharge 10.1
47 urethra adenocarcinoma 10.1
48 infertility 10.1
49 malakoplakia 10.1
50 posterior urethral valves 10.1

Comorbidity relations with Urethral Diverticulum via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Diverticulum:



Diseases related to Urethral Diverticulum
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Symptoms & Phenotypes for Urethral Diverticulum

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Drugs & Therapeutics for Urethral Diverticulum

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Drugs for Urethral Diverticulum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone Approved, Vet_approved 50-24-8 5755
2
Methylprednisolone hemisuccinate Approved 2921-57-5
3
Methylprednisolone Approved, Vet_approved 83-43-2 6741
4
Prednisolone phosphate Approved, Vet_approved 302-25-0
5 Prednisolone acetate Approved, Vet_approved 52-21-1
6
Epinephrine Approved, Vet_approved 51-43-4 5816
7
Ropivacaine Approved 84057-95-4 71273 175805
8
Racepinephrine Approved 329-65-7 838
9
Prednisolone hemisuccinate Experimental 2920-86-7
10 Methylprednisolone Acetate
11 Antiemetics
12 Gastrointestinal Agents
13 Hormone Antagonists
14 Anti-Inflammatory Agents
15 Autonomic Agents
16 Protective Agents
17 Neuroprotective Agents
18 Antineoplastic Agents, Hormonal
19 glucocorticoids
20 Hormones
21 Cola
22 Anesthetics, Local
23 Anesthetics
24 Epinephryl borate
25 Central Nervous System Depressants

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair Recruiting NCT02162810 Prednisolone;placebo-controlled
2 Effect of Caudal and Penile Block on Hypospadias Repair Complications Recruiting NCT02851290

Search NIH Clinical Center for Urethral Diverticulum

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Genetic Tests for Urethral Diverticulum

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Anatomical Context for Urethral Diverticulum

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MalaCards organs/tissues related to Urethral Diverticulum:

40
Prostate, Kidney, Spinal Cord, Skin, Testis, Testes, Small Intestine
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Publications for Urethral Diverticulum

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Articles related to Urethral Diverticulum:

(show top 50) (show all 719)
# Title Authors PMID Year
1
Robotic Excision of Vaginal Remnant/Urethral Diverticulum for Relief of Urinary Symptoms Following Phalloplasty in Transgender Men. 61
31790784 2020
2
Laparoscopic surgical technique to enhance the management of anorectal malformations: 330 cases' experience in a single center. 61
31919580 2020
3
Free Tube Graft Urethroplasty for Repair of Hypospadias. 61
31801150 2019
4
Urethral diverticulum in pregnancy: a case report. 61
30879101 2019
5
In Search of Mobile Applications for Urogynecology Providers. 61
29649079 2019
6
The use of tomographic ultrasound imaging on three-dimensional translabial ultrasound: a diagnostic sign for urethral diverticulum. 61
31781823 2019
7
Urethral diverticulum with urethrocutaneous fistula and giant stone: A case report. 61
31687341 2019
8
Risk factors of postoperative sexual function in patients with urethral diverticulum and their partners: A cohort study of 83 women. 61
31808411 2019
9
Penile urethroplasty using Orandi's dorsal skin flap: a new technique. 61
31351018 2019
10
Translabial ultrasound imaging of urethral diverticula. 61
31038237 2019
11
Diagnosis and management of a remnant of the original fistula (ROOF) in males following surgery for anorectal malformations. 61
30879755 2019
12
The incidence and outcomes of urodynamic stress urinary incontinence in female patients with urethral diverticulum. 61
31270839 2019
13
Urethral diverticula in women are associated with increased urethra-sphincter complex volumes: A potential role for high-tone nonrelaxing sphincter in their etiology? 61
31278796 2019
14
Urethral diverticular with broadly squamous metaplasia in a patient with urethral diverticular calculi: A case report. 61
31441877 2019
15
Can magnetic resonance imaging differentiate among transurethral bulking agent, urethral diverticulum, and periurethral cyst? 61
31069481 2019
16
"Horseshoe" sign in a female urethral diverticulum. 61
30976826 2019
17
Giant urethral calculus in anterior urethral diverticulum: a case report. 61
31357972 2019
18
Synchronous Urethral Repair During Prosthetic Surgery: Safety of Planned and Damage Control Approaches Using Suprapubic Tube Urinary Diversion. 61
30962156 2019
19
Giant anterior urethra stones combined with a diverticulum: a case report. 61
31155906 2019
20
Female Urethral Diverticula: Diagnosis, Pathology, and Surgical Outcomes at an Academic, Urban Medical Center. 61
30844385 2019
21
Surgical management of hypospadias in cases with concomitant disorders of sex development. 61
30762107 2019
22
Managing female urethral diverticulum with a standardized technique using a pacifier-trick artifice to facilitate dissection. 61
30178127 2019
23
Buccal mucosa graft for simultaneous correction of severe chordee and urethroplasty as a one-stage repair of scrotal hypospadias (watch technique). 61
30306261 2019
24
Urethral diverticulum: A systematic review. 61
31258943 2019
25
Primary Small Cell Neuroendocrine Tumor Within a Urethral Diverticulum. 61
30633138 2019
26
[Reoperation methods and effectiveness of urethral stricture after urethroplasty of hypospadias]. 61
30739420 2019
27
A Rare Case of Advanced Urethral Diverticular Adenocarcinoma and a Review of Treatment Modalities. 61
30739492 2019
28
Correlation of MRI features of urethral diverticulum and pre- and post-operative stress urinary incontinence. 61
30411812 2019
29
Post void incontinence secondary to female urethral diverticulum. 61
30741660 2019
30
[Urethral diverticulum occurring after urethromeatoplasty: a case study]. 61
31565140 2019
31
Periurethral Abscess Complicating Urethral Diverticulum. 61
30253950 2018
32
Single-Incision Laparoscopic Versus Conventional Laparoscopic Surgery for Rectobladderneck and Rectoprostatic Anorectal Malformations. 61
30067133 2018
33
Preoperative Transurethral Contrast-Enhanced Ultrasonography in the Diagnosis of Female Urethral Diverticula. 61
29689620 2018
34
A 10-Year Case Series of Surgically Managed Periurethral Masses at a Single Tertiary Care Institution. 61
31742566 2018
35
Female urethral diverticulum containing calculi: A rare and tricky condition. 61
30263891 2018
36
Long-term outcomes and complications after laparoscopic-assisted anorectoplasty vs. posterior sagittal anorectoplasty for high- and intermediate-type anorectal malformation. 61
30120550 2018
37
Enterolithiasis in posterior urethral diverticulum: an uncommon complication following surgery for anorectal malformation. 61
30209147 2018
38
Urethral diverticulum repair using diverticulum wall: A new technique for preparing covering flap layer. 61
29998061 2018
39
Urethral diverticulum carcinoma in females-a case series and review of the English and Japanese literature. 61
30211061 2018
40
One-Stage Laparoscopic-Assisted Anorectoplasty for Neonates with Anorectal Malformation and Recto-Prostatic or Recto-Bulbar Fistula According to the Krickenbeck Classification. 61
29741982 2018
41
Radiographic Misdiagnoses After Periurethral Bulking Agents. 61
28657999 2018
42
[Two Cases of Clear Cell Adenocarcinoma Arising in Urethral Diverticulum]. 61
30089340 2018
43
Rare cause of voiding dysfunction in an adult man: urethral diverticulum compressing the anterior urethra. 61
30012683 2018
44
Giant urethral diverticulum calculus revealed by peri-urethral abscess. 61
30430479 2018
45
Female urethral diverticulum containing large calculi. 61
29686963 2018
46
Incidental Finding of Urethral Diverticulum in a Woman with History of Recurrent Urinary Tract Infections. 61
29692697 2018
47
Suspected congenital urethral diverticulum in a dog. 61
29599553 2018
48
Posterior hypospadias: Evaluation of a paradigm shift from single to staged repair. 61
28865886 2018
49
[A Case of Clear Cell Adenocarcinoma Arising from a Female Urethral Diverticulum]. 61
29684952 2018
50
A Case of Urethral Diverticulum with Surgical Repair Using Cadaveric Pericardial Tissue. 61
30519496 2018
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Variations for Urethral Diverticulum

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Expression for Urethral Diverticulum

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Search GEO for disease gene expression data for Urethral Diverticulum.
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Pathways for Urethral Diverticulum

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GO Terms for Urethral Diverticulum

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Sources for Urethral Diverticulum

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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