MCID: URT016
MIFTS: 30

Urethral Diverticulum

Categories: Nephrological diseases

Aliases & Classifications for Urethral Diverticulum

MalaCards integrated aliases for Urethral Diverticulum:

Name: Urethral Diverticulum 12 15 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:9341
ICD9CM 34 599.2
NCIt 49 C39861
SNOMED-CT 67 90531003
ICD10 32 N36.1
UMLS 71 C0152443

Summaries for Urethral Diverticulum

MalaCards based summary : Urethral Diverticulum is related to acute cystitis and urethral calculus. An important gene associated with Urethral Diverticulum is MCU (Mitochondrial Calcium Uniporter). The drugs Prednisolone phosphate and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include prostate, skin and spinal cord.

Wikipedia : 74 A urethral diverticulum is a condition where the urethra or the periurethral glands push into the... more...

Related Diseases for Urethral Diverticulum

Diseases related to Urethral Diverticulum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 163)
# Related Disease Score Top Affiliating Genes
1 acute cystitis 31.0 UPK3A MCU KLK3
2 urethral calculus 30.7 MCU KLK3
3 urethral stricture 30.4 MCU LINC00538 KLK3 BCL2L10
4 chronic cystitis 30.4 UPK3A KRT7
5 pyuria 30.3 UPK3A KLK3
6 transitional cell carcinoma 30.3 UPK3A KRT7 KLK3
7 prostatic cyst 30.2 KLK3 BCL2L10
8 ureterocele 30.2 PAX8 MCU
9 urethra adenocarcinoma 30.0 KLK3 AMACR
10 hydronephrosis 29.7 UPK3A KRT7 KLK3
11 mucinous adenocarcinoma 29.7 KRT7 AMACR
12 urethral syndrome 29.6 MCU KLK3 AMACR
13 clear cell adenocarcinoma 29.6 PAX8 KRT7 KLK3 AMACR
14 nephrogenic adenoma 29.5 PAX8 KRT7 KLK3 AMACR
15 cystadenoma 29.5 KRT7 KLK3
16 female urethral cancer 29.3 KRT7 KLK3 AMACR
17 suppression of tumorigenicity 12 29.1 KRT7 KLK3 AMACR
18 adenocarcinoma 10.6
19 adenoma 10.5
20 cystitis 10.4
21 hypospadias 10.4
22 urinary tract obstruction 10.3
23 renal pelvis transitional cell carcinoma 10.3 UPK3A KRT7
24 vulva adenocarcinoma 10.3 UPK3A KRT7
25 vulval paget's disease 10.2 UPK3A KRT7
26 gastric squamous cell carcinoma 10.2 UPK3A KRT7
27 squamous cell carcinoma 10.2
28 urethral cancer 10.2
29 spinal cord injury 10.2
30 papillary transitional carcinoma 10.2 UPK3A KRT7
31 bladder neck obstruction 10.2 KLK3 BCL2L10
32 transitional papilloma 10.2 UPK3A KRT7
33 ovarian brenner tumor 10.2 UPK3A KRT7
34 ureteral benign neoplasm 10.2 UPK3A KRT7
35 radiation cystitis 10.2 UPK3A KLK3
36 cystitis cystica 10.2 KRT7 KLK3
37 endometriosis 10.2
38 paraplegia 10.2
39 in situ carcinoma 10.2
40 47,xyy 10.2
41 ureteral disease 10.2 UPK3A MCU
42 eccrine papillary adenocarcinoma 10.1 KRT7 KLK3
43 rete testis neoplasm 10.1 PAX8 KRT7
44 rete testis adenocarcinoma 10.1 PAX8 KRT7
45 ovarian seromucinous carcinoma 10.1 PAX8 KRT7
46 renal pelvis adenocarcinoma 10.1 PAX8 KRT7
47 prostate neuroendocrine neoplasm 10.1 KRT7 KLK3
48 krukenberg carcinoma 10.1 PAX8 KRT7
49 ovarian large-cell neuroendocrine carcinoma 10.1 PAX8 KRT7
50 uterus perivascular epithelioid cell tumor 10.1 PAX8 KRT7

Comorbidity relations with Urethral Diverticulum via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Diverticulum:



Diseases related to Urethral Diverticulum

Symptoms & Phenotypes for Urethral Diverticulum

Drugs & Therapeutics for Urethral Diverticulum

Drugs for Urethral Diverticulum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone phosphate Approved, Vet_approved 302-25-0
2
Methylprednisolone Approved, Vet_approved 83-43-2 6741
3
Methylprednisolone hemisuccinate Approved 2921-57-5
4 Prednisolone acetate Approved, Vet_approved 52-21-1
5
Prednisolone Approved, Vet_approved 50-24-8 5755
6
Epinephrine Approved, Vet_approved 51-43-4 5816
7
Ropivacaine Approved 84057-95-4 71273 175805
8
Racepinephrine Approved 329-65-7 838
9
Prednisolone hemisuccinate Experimental 2920-86-7
10 Hormones
11 Methylprednisolone Acetate
12 glucocorticoids
13 Hormone Antagonists
14 Antineoplastic Agents, Hormonal
15 Cola
16 Anti-Inflammatory Agents
17 Anesthetics
18 Epinephryl borate
19 Anesthetics, Local

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair Recruiting NCT02162810 Prednisolone;placebo-controlled
2 Effect of Caudal and Penile Block on Hypospadias Repair Complications Recruiting NCT02851290

Search NIH Clinical Center for Urethral Diverticulum

Genetic Tests for Urethral Diverticulum

Anatomical Context for Urethral Diverticulum

MalaCards organs/tissues related to Urethral Diverticulum:

40
Prostate, Skin, Spinal Cord, Testes, Small Intestine, Colon, Kidney

Publications for Urethral Diverticulum

Articles related to Urethral Diverticulum:

(show top 50) (show all 735)
# Title Authors PMID Year
1
Clear cell carcinoma in a urethral diverticulum. 61
32435592 2020
2
Surgical management of a large iatrogenic urethral diverticulum in a male patient: A case report. 61
32257819 2020
3
The use of tomographic ultrasound imaging on three-dimensional translabial ultrasound: a diagnostic sign for urethral diverticulum. 61
31781823 2020
4
Treatment validation of the Solomon-Greenwell nomogram for female bladder outlet obstruction. 61
32249980 2020
5
Urethral diverticulum with giant calculus: an unusual cause of prolonged lower urinary tract symptoms. 61
32556407 2020
6
Video and review of the surgical management of recurrent urethral diverticulum. 61
32494960 2020
7
Circumferential urethral diverticulum: a surgical conundrum. 61
32529564 2020
8
Complex extensive urethral diverticulum on pelvic floor ultrasound and MRI. 61
32535686 2020
9
Urethral Triplication with Diverticulum Malformation: A Case Report and Literature Review. 61
32512109 2020
10
Urethral Catheter Induced Huge Anterior Urethral Diverticulum. 61
32109498 2020
11
Reconstructing forked corpus spongiosum to correct glans droop in distal/midshaft hypospadias repair. 61
32459109 2020
12
A persistent urethral diverticulum in pregnancy: Case report and review of the literature. 61
32257827 2020
13
Erosion of Mesh Mid-urethral Sling Into a Complex Urethral Diverticulum: Diagnosis, Evaluation, and Surgical Management. 61
32348805 2020
14
"Sandwich" mesh reconstruction of female giant urethral diverticulum: a case report. 61
32197612 2020
15
Laparoscopic surgical technique to enhance the management of anorectal malformations: 330 cases' experience in a single center. 61
31919580 2020
16
Robotic Excision of Vaginal Remnant/Urethral Diverticulum for Relief of Urinary Symptoms Following Phalloplasty in Transgender Men. 61
31790784 2020
17
Corpus Cavernosum Abscess Secondary to Traumatic Perforation of Urethral Diverticulum. 61
32211265 2020
18
Free Tube Graft Urethroplasty for Repair of Hypospadias. 61
31801150 2020
19
Urethral Diverticulum following Polypropylene Mesh Midurethral Slings: A Literature Review. 61
32462011 2020
20
Impact of Cystotomy Location on Cystography Results. 61
32217915 2020
21
Urethral diverticulum in pregnancy: a case report. 61
30879101 2019
22
In Search of Mobile Applications for Urogynecology Providers. 61
29649079 2019
23
Urethral diverticulum with urethrocutaneous fistula and giant stone: A case report. 61
31687341 2019
24
Penile urethroplasty using Orandi's dorsal skin flap: a new technique. 61
31351018 2019
25
Risk factors of postoperative sexual function in patients with urethral diverticulum and their partners: A cohort study of 83 women. 61
31808411 2019
26
Translabial ultrasound imaging of urethral diverticula. 61
31038237 2019
27
Diagnosis and management of a remnant of the original fistula (ROOF) in males following surgery for anorectal malformations. 61
30879755 2019
28
The incidence and outcomes of urodynamic stress urinary incontinence in female patients with urethral diverticulum. 61
31270839 2019
29
Urethral diverticula in women are associated with increased urethra-sphincter complex volumes: A potential role for high-tone nonrelaxing sphincter in their etiology? 61
31278796 2019
30
Urethral diverticular with broadly squamous metaplasia in a patient with urethral diverticular calculi: A case report. 61
31441877 2019
31
Can magnetic resonance imaging differentiate among transurethral bulking agent, urethral diverticulum, and periurethral cyst? 61
31069481 2019
32
"Horseshoe" sign in a female urethral diverticulum. 61
30976826 2019
33
Giant urethral calculus in anterior urethral diverticulum: a case report. 61
31357972 2019
34
Synchronous Urethral Repair During Prosthetic Surgery: Safety of Planned and Damage Control Approaches Using Suprapubic Tube Urinary Diversion. 61
30962156 2019
35
Giant anterior urethra stones combined with a diverticulum: a case report. 61
31155906 2019
36
Female Urethral Diverticula: Diagnosis, Pathology, and Surgical Outcomes at an Academic, Urban Medical Center. 61
30844385 2019
37
Surgical management of hypospadias in cases with concomitant disorders of sex development. 61
30762107 2019
38
Managing female urethral diverticulum with a standardized technique using a pacifier-trick artifice to facilitate dissection. 61
30178127 2019
39
Buccal mucosa graft for simultaneous correction of severe chordee and urethroplasty as a one-stage repair of scrotal hypospadias (watch technique). 61
30306261 2019
40
Urethral diverticulum: A systematic review. 61
31258943 2019
41
Primary Small Cell Neuroendocrine Tumor Within a Urethral Diverticulum. 61
30633138 2019
42
[Reoperation methods and effectiveness of urethral stricture after urethroplasty of hypospadias]. 61
30739420 2019
43
A Rare Case of Advanced Urethral Diverticular Adenocarcinoma and a Review of Treatment Modalities. 61
30739492 2019
44
Correlation of MRI features of urethral diverticulum and pre- and post-operative stress urinary incontinence. 61
30411812 2019
45
Post void incontinence secondary to female urethral diverticulum. 61
30741660 2019
46
[Urethral diverticulum occurring after urethromeatoplasty: a case study]. 61
31565140 2019
47
Periurethral Abscess Complicating Urethral Diverticulum. 61
30253950 2018
48
Single-Incision Laparoscopic Versus Conventional Laparoscopic Surgery for Rectobladderneck and Rectoprostatic Anorectal Malformations. 61
30067133 2018
49
Preoperative Transurethral Contrast-Enhanced Ultrasonography in the Diagnosis of Female Urethral Diverticula. 61
29689620 2018
50
A 10-Year Case Series of Surgically Managed Periurethral Masses at a Single Tertiary Care Institution. 61
31742566 2018

Variations for Urethral Diverticulum

Expression for Urethral Diverticulum

Search GEO for disease gene expression data for Urethral Diverticulum.

Pathways for Urethral Diverticulum

GO Terms for Urethral Diverticulum

Sources for Urethral Diverticulum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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