Urethral Stricture disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: URT037 MIFTS: 45	Urethral Stricture Categories: Nephrological diseases	Data Licensing For inquiries, contact: [email protected]
Genes Variations Tissues Related diseases Publications Drugs Expand all tables

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Aliases & Classifications for Urethral Stricture

MalaCards integrated aliases for Urethral Stricture:

Name: Urethral Stricture ¹¹ ⁵³ ⁵ ⁴³ ¹⁴ ⁷¹ ⁷⁵ ³¹ ³³

Stricture of Urinary Meatus ³³

Constriction of Urethra ³³

Contraction of Urethra ³³

Urethral Obliteration ³³

Urethral Contracture ³³

Urethral Obstruction ³³

Meatal Stenosis Nos ³³

Urethral Narrowing ³³

Pinhole Meatus Nos ³³

Urethral Occlusion ³³

Urethral Stenosis ³³

Pinpoint Meatus ³³

Ankylurethria ³³

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases

See all MalaCards categories (disease lists)

ICD10: ³¹

Diseases of the genitourinary system

Other diseases of urinary system

Urethral stricture

Urethral stricture, unspecified

ICD11: ³³

Diseases of the genitourinary system

Diseases of the urinary system

Certain specified diseases of urinary system

Urethral stricture

External Ids:

Disease Ontology ¹¹ DOID:1829

ICD9CM ³⁴ 598.8

MeSH ⁴³ D014525

ICD10 ³¹ N35 N35.9

ICD11 ³³ 611219038

UMLS ⁷¹ C0029752 C0041974

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Summaries for Urethral Stricture

MalaCards based summary: Urethral Stricture, also known as stricture of urinary meatus, is related to urethral syndrome and bladder neck obstruction. An important gene associated with Urethral Stricture is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways are Adhesion and Angiotensin II receptor type 1 pathway. The drugs Bupivacaine and Celecoxib have been mentioned in the context of this disorder. Affiliated tissues include prostate, spinal cord and skin.

Wikipedia: ⁷⁵ A urethral stricture is a narrowing of the urethra, the tube connected to the bladder that allows the... more...

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Related Diseases for Urethral Stricture

Diseases related to Urethral Stricture via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 291)

#	Related Disease	Score	Top Affiliating Genes
1	urethral syndrome	31.4	UPK3A PDE5A KLK3 CRP BOLL
2	bladder neck obstruction	31.1	PDE5A KLK3
3	urinary tract infection	30.9	UPK3A KLK3 CRP
4	urethritis	30.9	KLK3 CRP
5	prostatic hyperplasia, benign	30.9	PDE5A KLK3 FOLH1
6	impotence	30.8	TGFB1 PDE5A KLK3 ADRA1D
7	urethral diverticulum	30.6	UPK3A KLK3 BOLL
8	prostatitis	30.5	TGFB1 PDE5A KLK3
9	epididymo-orchitis	30.5	KLK3 CRP
10	urethra cancer	30.2	UPK3A KLK3
11	urinary tract obstruction	30.1	UPK3A TGFB1 KLK3 CRP CCN2
12	vesicoureteral reflux	30.0	UPK3A UPK2 CRP
13	renal fibrosis	30.0	TGFB1 MIR21 CCN2
14	chronic kidney disease	30.0	TGFB1 MIR21 CRP CCN2
15	pyuria	29.9	UPK3A KLK3 CRP
16	neurogenic bladder	29.8	UPK3A PDE5A KLK3 CRP
17	transitional cell carcinoma	29.8	UPK3A UPK2 KLK3
18	hydronephrosis	29.8	UPK3A UPK2 TGFB1 KLK3 CRP
19	phimosis	29.7	FERMT1 CRP
20	prostatic hypertrophy	29.7	PDE5A KLK3 FOLH1 CRP ADRA1D
21	skin disease	29.3	PLEC MIR21 FERMT1 CRP CCN2
22	cervical ribs, sprengel anomaly, anal atresia, and urethral obstruction	11.4
23	partington syndrome	11.2
24	infective urethral stricture	11.2
25	anterior urethral valve	11.1
26	epidermolysis bullosa simplex 5c, with pyloric atresia	11.1
27	lower urinary tract obstruction, congenital	11.1
28	dyskeratosis congenita	11.1
29	prostate embryonal rhabdomyosarcoma	11.1
30	hypospadias	10.7
31	lichen sclerosus et atrophicus	10.7
32	common cold	10.4
33	sexual health disorder	10.4
34	prostate cancer	10.3
35	cystitis	10.3
36	female stress incontinence	10.3	PDE5A KLK3
37	nodular prostate	10.3	KLK3 FOLH1
38	prostate cancer, hereditary, 8	10.3
39	prostate cancer, hereditary, 6	10.3
40	balanitis	10.3
41	balanitis xerotica obliterans	10.3
42	urethral calculus	10.3
43	prostatic acinar adenocarcinoma	10.3	KLK3 FOLH1
44	prostate small cell carcinoma	10.3	KLK3 FOLH1
45	peyronie disease	10.3	TGFB1 PDE5A
46	cystitis cystica	10.2	UPK2 KLK3
47	prostate neuroendocrine neoplasm	10.2	KLK3 FOLH1
48	castration-resistant prostate carcinoma	10.2	KLK3 FOLH1
49	urinary tract infections, recurrent	10.2
50	orchitis	10.2

Comorbidity relations with Urethral Stricture via Phenotypic Disease Network (PDN): (show all 25)

Graphical network of the top 20 diseases related to Urethral Stricture:

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Symptoms & Phenotypes for Urethral Stricture

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Drugs & Therapeutics for Urethral Stricture

Drugs for Urethral Stricture (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 49)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Bupivacaine

Approved, Investigational

Phase 4

2180-92-9, 38396-39-3

2474

Celecoxib

Approved, Investigational

Phase 4

169590-42-5

2662

Dexamethasone acetate

Approved, Investigational, Vet_approved

Phase 4

1177-87-3

3680

Dexamethasone

Approved, Investigational, Vet_approved

Phase 4

50-02-2

3003 5743

Acetaminophen

Approved

Phase 4

103-90-2

1983

Ibuprofen

Approved

Phase 4

15687-27-1

3672

Oxycodone

Approved, Illicit, Investigational

Phase 4

76-42-6

5284603

Gabapentin

Approved, Investigational

Phase 4

60142-96-3

3446

Anesthetics, Local

Phase 4

Antirheumatic Agents

Phase 4

Antineoplastic Agents, Hormonal

Phase 4

Antipyretics

Phase 4

Hormones

Phase 4

Hormone Antagonists

Phase 4

Cyclooxygenase Inhibitors

Phase 4

Cyclooxygenase 2 Inhibitors

Phase 4

Antiemetics

Phase 4

Anti-Inflammatory Agents, Non-Steroidal

Phase 4

glucocorticoids

Phase 4

BB 1101

Phase 4

Analgesics, Opioid

Phase 4

Analgesics, Non-Narcotic

Phase 4

Anti-Inflammatory Agents

Phase 4

Gastrointestinal Agents

Phase 4

Narcotics

Phase 4

Analgesics

Phase 4

Neurotransmitter Agents

Phase 4

Anti-Anxiety Agents

Phase 4

Excitatory Amino Acid Antagonists

Phase 4

Psychotropic Drugs

Phase 4

Anticonvulsants

Phase 4

Silicon

Approved, Investigational

Phase 2, Phase 3

7440-21-3

4082203

Racepinephrine

Approved, Vet_approved

Phase 3

51-43-4, 329-65-7

838 5816

Lidocaine

Approved, Vet_approved

Phase 3

137-58-6

3676

Pharmaceutical Solutions

Phase 3

Epinephryl borate

Phase 3

Hemostatics

Phase 3

Mitomycin

Approved

Phase 1, Phase 2

50-07-7

5746

Anti-Bacterial Agents

Phase 1, Phase 2

Alkylating Agents

Phase 1, Phase 2

Antibiotics, Antitubercular

Phase 1, Phase 2

Fibrin Tissue Adhesive

Phase 1

Triamcinolone

Approved, Vet_approved

124-94-7

31307

Paclitaxel

Approved, Vet_approved

33069-62-4

36314

Triamcinolone hexacetonide

Triamcinolone diacetate

Triamcinolone Acetonide

6436

Albumin-Bound Paclitaxel

Anesthetics

Interventional clinical trials:

(show all 43)

#	Name	Status	NCT ID	Phase	Drugs
1	Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures	Unknown status	NCT01196572	Phase 4
2	Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty	Recruiting	NCT03859024	Phase 4	Oxycodone;Acetaminophen;Gabapentin;celebrex;Bupivacaine;Ibuprofen 800 mg;Dexamethasone
3	Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters	Recruiting	NCT05383274	Phase 4
4	Effect of Preoperative Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion: a Double Blind, Randomized, Placebo Controlled Trial	Terminated	NCT03151746	Phase 4	Placebo;Gabapentin
5	Diagnosis of Urethral Stricture With Sono-urethrography vs Conventional Urethrography: Evaluation of the Diagnostic Value and Evaluation of the Reduction of the Radiation Dose With Sono-urethrography (SONO-URETHRA)	Unknown status	NCT01790776	Phase 3
6	Liposomal Bupivacaine To Control Post-Operative Pain Following Buccal Mucosal Graft Harvesting	Completed	NCT03720223	Phase 3	Liposomal Bupivacaine
7	Holmium: YAG Versus Cold Knife Internal Urethrotomy in Management of Short Urethral Strictures: A Randomized Controlled Trial	Completed	NCT04650347	Phase 2, Phase 3
8	Prospective, Randomized, Controlled, Multicenter Trial of the Memokath® 044TW Thermo-Expandable Stent for Maintaining Urethral Patency in Patients After Dilation or Internal Urethrotomy of Recurrent Stricture of the Bulbar Urethra	Completed	NCT00270504	Phase 3
9	Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty: Randomized Control Trial of Harvest Site Anesthetic	Recruiting	NCT05300685	Phase 3	Standard Buccal Harvest;Basic buccal procedure + Long acting local;Basic buccal procedure + Buccal block
10	Effectiveness and Safety of Endoscopically-Assisted Submucosal Administration of Autologous Adipose-Derived Regenerative Cells for the Treatment of Urethral Strictures	Unknown status	NCT01889888	Phase 1, Phase 2
11	POIROT TRIAL: Post-Operative Imaging After Urethroplasty With Peri-catheter Retrograde Urethrography Or Trial of Voiding With Voiding Cysto-urethrography	Unknown status	NCT04307537	Phase 2
12	Effect of Mitomycin C on Urethral Stricture Recurrence After Internal Urethrotomy	Unknown status	NCT00918528	Phase 1, Phase 2	Mitomycin C - local injection
13	Role of Uttarbasti in the Management of Mutra Marga Sankoch (Urethral Stricture)	Completed	NCT00535717	Phase 2
14	Clostridium Histolyticum Collagenase Injection Treatment for Urethral Disease: a Prospective, Single-center, Open-label Study	Recruiting	NCT02948842	Phase 2	Clostridium Histolyticum Collagenase
15	Endoscopic Buccal Mucosal Graft Urethroplasty or Bladder Neck Reconstruction	Unknown status	NCT03061344	Phase 1
16	A Phase 1 Pilot Safety and Feasibility Study of Autologous Engineered Urethral	Not yet recruiting	NCT03258658	Phase 1
17	An Open Prospective Clinical Study on Safety and Efficacy of Surgical Treatment of Patients With Anterior Urethral Stricture Using a Tissue-engineered Construct Based on Autologous Buccal Mucosa Cells and Matrix From Reconstituted Collagen and Reinforcing Polylactoglycolide Fibers	Unknown status	NCT03205670	Early Phase 1
18	Prospective Long-term Single Center Cohort Study Assessing Functional Outcome of Urethral Reconstructive Surgery	Completed	NCT01982136
19	Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty	Completed	NCT04357080
20	Role of Oral Steroids in Reducing Recurrence of Urethral Stricture After Direct Vision Internal Urethrotomy	Completed	NCT05069883		Steroid Drug;No steroid
21	Scandinavian Urethroplasty Study. A Multicentre, Prospective, Randomized Study Comparing Bulbar Urethroplasty With Excision and Primary Anastomosis or With an Onlay Grafting Procedure Using Buccal Mucosa.	Completed	NCT02321670
22	PASTIS-Trial: Pre-operative Assessment by Sonourethrography Only in Anterior Urethral Strictures: A Prospective Feasibility Trial	Completed	NCT04452890
23	Urethral Stricture Repair: A Prospective Randomized Analysis Between Jugal or Labial Graft in Buccal Mucosa Urethroplasty	Completed	NCT03973619
24	Efficacy of Holmium Laser Uretherotomy in Combination With Intralesional Steroids in the Treatment of Bulbar Uretheral Stricture	Completed	NCT05078788
25	Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Urethral Strictures	Recruiting	NCT04161365
26	DoVe Trial: a Randomized Controlled Trial Comparing Dorsal Onlay Versus Ventral Onlay in Isolated Bulbar Urethral Strictures	Recruiting	NCT04551417
27	Hormonal Status and Coagulative Disorders as Risk Factors for Urethral Stricture After Transurethral Resection of the Prostate/Bladder: A Prospective Study	Recruiting	NCT04795570
28	VeSpAR: A Randomized Controlled Trial Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Urethral Strictures	Recruiting	NCT03572348
29	Bioengineered Collagen Scaffold Implant as an Alternative to Conventional Buccal Mucosa for Substitution Urethroplasty of Distal Urethral Strictures. - A Pilot Stud	Recruiting	NCT05463991
30	Nonfat Grafting in Male and Female Genital Lichen Sclerosus	Recruiting	NCT05464290
31	MAGIC I TRIAL - Multi-stage Urethroplasty With Augmentation Using a Dorsal Graft Inlay Technique Comparing Graft Use in First or Second Stage: a Randomized Controlled Pilot Study	Recruiting	NCT04965025
32	New Autologous Fat Graft for the Treatment of Urethral Stricture	Recruiting	NCT05451732
33	Validation of the Standardized Prenatal Clinical Management of Fetuses With Lower Urinary Tract Obstruction (LUTO)	Recruiting	NCT02315521
34	Re-establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease	Active, not recruiting	NCT03270384
35	ROBUST III - Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease - A Randomized Control Trial	Active, not recruiting	NCT03499964
36	ROBUST I Pilot Study, ROBUST I Study, Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease	Active, not recruiting	NCT03014726
37	The Diagnostic Accuracy of Pulsed Fluoroscopy Retrograde Urethrogram Vs the Traditional Retrograde Urethrogram In Diagnosing Urethral Stricture: A Randomized Prospective Comparative Study	Not yet recruiting	NCT05519566
38	9000 URETHRA STUDY: a Prospective, Observational Study About Urethroplasty for Urethral Stricture Disease	Not yet recruiting	NCT04071925
39	European Clinical Registry for Optilume Urethral Drug Coated Balloon	Not yet recruiting	NCT05479422
40	A Randomized Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar Urethroplasty	Terminated	NCT02634619
41	A Randomized Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar Urethroplasty	Terminated	NCT02551783
42	Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction - a Prospective Trial	Terminated	NCT02446184
43	Re-Establishing Flow Via Drug Coated Balloon for the Treatment of Urethral Stricture Disease - Registry Study	Withdrawn	NCT03851952

Search NIH Clinical Center for Urethral Stricture

Cochrane evidence based reviews: urethral stricture

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Genetic Tests for Urethral Stricture

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Anatomical Context for Urethral Stricture

Organs/tissues related to Urethral Stricture:

MalaCards : Prostate, Spinal Cord, Skin, Smooth Muscle, Bone Marrow, Kidney, Testis

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Publications for Urethral Stricture

Articles related to Urethral Stricture:

(show top 50) (show all 4978)

#	Title	Authors	PMID	Year
1	Factors affecting urethral stricture development after radical retropubic prostatectomy. ⁵³ ⁶²	Altinova S...Balbay MD	19165616	2009
2	Short-term results of rotoresection for benign prostatic hyperplasia: a prospective study of safety and efficacy. ⁵³ ⁶²	Wadie BS...Ghoneim MA	14616452	2003
3	Biomarkers in Urethral Stricture Disease and Benign Lower Urinary Tract Disease. ⁶²	Campbell JG...Vanni AJ	36424081	2023
4	Circular RNA ACTR2 activates M2 polarization of macrophages through activating Yes-associated protein signalling and contributes to renal fibrosis. ⁶²	Fu H...Wang GH	36069177	2022
5	Urologic dermatology: a comprehensive foray into the noninfectious etiologies of balanitis. ⁶²	Nemirovsky DR...Malik RD	34826136	2022
6	Effect of intermittent bladder flushing on recurrence rate in feline urethral obstruction: 72 cases. ⁶²	Tsuruta K...Goic J	36467381	2022
7	Erectile and voiding function outcomes after buccal mucosa graft urethroplasty for long-segment bulbar urethral stricture: ventral versus dorsal onlay technique. ⁶²	Shalkamy O...Ibrahim A	36460798	2022
8	A Randomized Controlled Trial Comparing Two Different Local Intraurethral Anesthetics in Optical Internal Urethrotomy at the Outpatient Clinic. ⁶²	Ergun O...Aydemir S	36195164	2022
9	The application of 3D bioprinting in urological diseases. ⁶²	Xu K...Jiang J	35967737	2022
10	Treatment strategies for hyperkalemia secondary to urethral obstruction in 50 male cats: 2002-2017. ⁶²	Jones JM...Epstein SE	36350735	2022
11	The Outcomes of Pelvic Fracture Urethral Injuries Stratified by Urethral Injury Severity: A Prospective Multi-institutional Genitourinary Trauma Study (MiGUTS). ⁶²	Fendereski K...Myers JB	36152870	2022
12	Neutering is not associated with early-onset urethral obstruction in cats. ⁶²	Sampaio KO...da Silva ECB	36453601	2022
13	Sources, Selection, and Microenvironmental Preconditioning of Cells for Urethral Tissue Engineering. ⁶²	Xuan Z...Pennisi CP	36430557	2022
14	Posterior urethral stenosis: a comparative review of the guidelines. ⁶²	Abbasi B...Breyer BN	36018366	2022
15	Ventral onlay graft urethroplasty using bladder mucosa in a cat with a urethral stricture. ⁶²	Katayama M...Nakata K	36351592	2022
16	[Urethroplasty technological changes for the treatment of male urethral stricture]. ⁶²	Xiu XJ...Song LJ	36323579	2022
17	Addressing the Relationship Between Testosterone Levels and Urethral Stricture: A Case-Control Study. ⁶²	Puche-Sanz I...Lardelli-Claret P	35913438	2022
18	A novel case of female urethral stricture and repair. ⁶²	George EI...Medendorp AR	36248779	2022
19	Male urethral diverticulum without having urethral stricture: A rare case. ⁶²	Hosseini J...Abedi AR	36420477	2022
20	Predictive value of systemic immune-inflammation index in recurrent urethral strictures. ⁶²	Ozsoy E...Ozturk MI	36321780	2022
21	Urethral Cancer After Urethroplasty: A Case Report and Review of the Literature. ⁶²	D'Amico MJ...Chung PH	35914585	2022
22	Oncological and urinary outcomes following low-dose-rate brachytherapy with a median follow-up of 11.8 years. ⁶²	Yaxley WJ...Yaxley JW	35791775	2022
23	Evaluating Tools for Characterizing Anterior Urethral Stricture Disease: A Comparison of the LSE System and the Urethral Stricture Score. ⁶²	Kurtzman JT...Brandes SB	35913433	2022
24	Preputial urethrostomy with preservation of the local anatomy in 4 dogs. ⁶²	Giansetto T...Claeys S	36069396	2022
25	Clinical spectrum and management options for prostatic utricle in children. ⁶²	Gupta A...Samnakay N	35101262	2022
26	Prospective Assessment of Genital Pain in Patients With Urethral Stricture: Incidence, Associations, and Impact of Urethroplasty. ⁶²	Rourke D...Rourke KF	36343864	2022
27	Long-term outcomes of Blocksom vesicostomy for elderly patients with chronic urinary retention. ⁶²	Tobu S...Noguchi M	35945167	2022
28	Long-term treatment outcomes/toxicities of definite chemoradiotherapy (intensity-modulated radiation therapy) for early-stage "bulky" cervical cancer and survival impact of histological subtype. ⁶²	Hsieh HY...Wang L	36379808	2022
29	Technical details and long-term outcomes of P.A.D.U.A. for congenital urethral narrowing; a case series and review of the literature. ⁶²	Danzig MR...Ellison JS	36424292	2022
30	Which Are the Commonest Sites and Characteristics of Post-Transurethral Prostate Surgery Strictures in a High-Volume Reconstructive Center? ⁶²	Bandini M...Kulkarni SB	35699078	2022
31	The use of a modified tanagho flap in the repair of posterior urethral stricture after primary exstrophy closure. ⁶²	Guan H...Gearhart JP	36369236	2022
32	The effectiveness and safety of three surgical procedures for the treatment for benign prostatic hyperplasia: A network meta-analysis. ⁶²	Yan J...Zhang J	36267366	2022
33	Urethral and bladder neck stenosis after thulium laser enucleation of the prostate: Analysis of risk factors in a series of 1003 patients. ⁶²	Castellani D...Bove P	35789109	2022
34	The Long-term Effects of Transurethral Bladder Neck Incision in the Treatment of Female Bladder Neck Obstruction. ⁶²	Qin Y...Hu X	36242528	2022
35	Sodium butyrate ameliorates erectile dysfunction through fibrosis in a rat model of partial bladder outlet obstruction. ⁶²	Kaya-Sezginer E...Gur S	35852413	2022
36	Assessments of ReDo buccal mucosal urethroplasty in terms of functional outcomes. ⁶²	Topcuoglu M...Yalcinkaya F	35838830	2022
37	Morphological and histological changes in the urethra after intraurethral nonablative erbium YAG laser therapy: an experimental study in beagle dogs. ⁶²	Xu SF...Yuan XY	35614283	2022
38	Engraftment of Transplanted Buccal Epithelial Cells onto the Urethrotomy Site, Proven Immunohistochemically in Rabbit Model; a Feat to Prevent Urethral Stricture Recurrence. ⁶²	Horiguchi A...Abraham SJK	36306011	2022
39	An Update on Female Urethral Stricture Disease. ⁶²	Campbell J...Kowalik CG	36308672	2022
40	Outcomes Following Gender Affirming Phalloplasty: A Systematic Review and Meta-Analysis. ⁶²	Wang AMQ...Genoway K	36031521	2022
41	Quality and content analysis of female urethroplasty videos on YouTube. ⁶²	Sahin Y...Muslumanoglu AY	36310521	2022
42	Three-Piece Inflatable Penile Prosthesis Implantation for the Treatment of Severe Erectile Dysfunction Following a Complex Pelvic Fracture: A Case Report. ⁶²	Truong MH...Ngo TQ	36238423	2022
43	Assessment of serum symmetric dimethylarginine and creatinine concentrations in cats with urethral obstruction. ⁶²	Wilson KE...Szlosek D	34894831	2022
44	Irreversible Electroporation Balloon Therapy for Palliative Treatment of Obstructive Urethral Transitional Cell Carcinoma in Dogs. ⁶²	Marie Butty E...Labato MA	36049240	2022
45	[Use of urethral stents for urethral strictures]. ⁶²	Kyzlasov PS...Ostrovsky DV	36098603	2022
46	Anterior substitutional urethroplasty using a biomimetic poly-l-lactide nanofiber membrane: Preclinical and clinical outcomes. ⁶²	Song L...Fu Q	36176613	2022
47	A Novel Technique of Urethroplasty Could Reduce Urethra-Related Complications in Phalloplasty With Urethral Lengthening. ⁶²	Gao H...Zhu X	36182727	2022
48	Clinical application of a double-modified sulfated bacterial cellulose scaffold material loaded with FGFR2-modified adipose-derived stem cells in urethral reconstruction. ⁶²	Zhu Z...Zhou L	36068613	2022
49	Prospects and Challenges of Electrospun Cell and Drug Delivery Vehicles to Correct Urethral Stricture. ⁶²	Farzamfar S...Bolduc S	36142432	2022
50	Urethral Stricture/Stenosis as a Complication of High Intensity Focused Ultrasound of the Prostate (HIFU): What is the Overall Patient Experience? ⁶²	Barham DW...Gelman J	35680051	2022

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Genes for Urethral Stricture

Genes related to Urethral Stricture (0 elite genes):

(show all 16)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	KLK3	Kallikrein Related Peptidase 3	Protein Coding	16.46	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	19165616 14616452
2	CCN2	Cellular Communication Network Factor 2	Protein Coding	12.17	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
3	MIR21	MicroRNA 21	RNA Gene	10.85	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
4	PDE5A	Phosphodiesterase 5A	Protein Coding	6.12	DISEASES inferred ¹⁴
5	BOLL	Boule Homolog, RNA Binding Protein	Protein Coding	6.07	DISEASES inferred ¹⁴
6	MIR4691	MicroRNA 4691	RNA Gene	5.65	DISEASES inferred ¹⁴
7	FOLH1	Folate Hydrolase 1	Protein Coding	5.42	DISEASES inferred ¹⁴
8	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	5.31	DISEASES inferred ¹⁴
9	UPK2	Uroplakin 2	Protein Coding	5.16	DISEASES inferred ¹⁴
10	PLEC	Plectin	Protein Coding	5.1	DISEASES inferred ¹⁴
11	UPK3A	Uroplakin 3A	Protein Coding	5	DISEASES inferred ¹⁴
12	FERMT1	FERM Domain Containing Kindlin 1	Protein Coding	4.98	DISEASES inferred ¹⁴
13	ADRA1D	Adrenoceptor Alpha 1D	Protein Coding	4.88	DISEASES inferred ¹⁴
14	SRARP	Steroid Receptor Associated And Regulated Protein	Protein Coding	4.86	DISEASES inferred ¹⁴
15	TULP4	TUB Like Protein 4	Protein Coding	4.8	DISEASES inferred ¹⁴
16	CRP	C-Reactive Protein	Protein Coding	4.67	DISEASES inferred ¹⁴

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Variations for Urethral Stricture

ClinVar genetic disease variations for Urethral Stricture:

⁵

#	Gene	Name	Type	Significance	ClinVarId	dbSNP ID	Position
1	TBXAS1	GRCh37/hg19 7q34(chr7:139478979-139550968)	CN GAIN	Uncertain Significance	638674		GRCh37: 7:139478979-139550968 GRCh38:
2	GABRG3	GRCh37/hg19 15q12(chr15:27462869-27544157)	CN GAIN	Uncertain Significance	638675		GRCh37: 15:27462869-27544157 GRCh38: