Aliases & Classifications for Urethral Syndrome

Summaries for Urethral Syndrome

MedlinePlus : 43 The urethra is the tube that allows urine to pass out of the body. In men, it's a long tube that runs through the penis. It also carries semen in men. In women, it's short and is just above the vagina. Urethral problems may happen due to aging, illness, or injury. They include Urethral cancer - a rare cancer that happens more often in men Urethral stricture - a narrowing of the opening of the urethra Urethritis - inflammation of the urethra, sometimes caused by infection Urethral problems may cause pain or difficulty passing urine. You may also have bleeding or discharge from the urethra. Doctors diagnose urethral problems using different tests. These include urine tests, x-rays and an examination of the urethra with a scope called a cystoscope. Treatment depends on the cause of the problem. It may include medicines and, in severe cases, surgery.

MalaCards based summary : Urethral Syndrome, also known as urethral diseases, is related to urethritis and bacteriuria, and has symptoms including pain in urethra An important gene associated with Urethral Syndrome is MRAP (Melanocortin 2 Receptor Accessory Protein), and among its related pathways/superpathways is Primary immunodeficiency. The drugs Cholinergic Agents and Cholinergic Antagonists have been mentioned in the context of this disorder. Affiliated tissues include the urethra, testes and prostate.

Disease Ontology : 12 A urinary system disease that is located in the urethra.

Wikipedia : 76 Urethral syndrome is characterised by a set of symptoms typically associated with lower urinary tract... more...

Related Diseases for Urethral Syndrome

Diseases related to Urethral Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 162)
# Related Disease Score Top Affiliating Genes
1 urethritis 29.6 CD40LG CD79A MRAP MT-TG PHB2
2 bacteriuria 29.1 CD40LG CD79A
3 ophthalmia neonatorum 29.1 CD40LG CD79A
4 ochronosis 10.8 HPD MRAP
5 balanitis 10.8 MRAP PHB2
6 enthesopathy 10.8 MRAP PHB2
7 bursitis 10.8 MRAP PHB2
8 tendinitis 10.8 MRAP PHB2
9 penile disease 10.8 MRAP PHB2
10 acute cystitis 10.7 BCKDHA KLK3
11 bladder neck obstruction 10.7 KLK3 SAMHD1
12 prostatic cyst 10.6 BCL2L10 KLK3
13 purulent endophthalmitis 10.6 MRAP SAMHD1
14 urethral stricture 10.6 BCL2L10 KLK3
15 rectal disease 10.6 KIDINS220 KLK3
16 urethral diverticulum 10.5 KIDINS220 KLK3
17 chronic orbital inflammation 10.4 CD79A MRAP
18 pyuria 10.4 BCKDHA MN1 MRAP
19 anterior scleritis 10.4 CD79A MRAP
20 optic papillitis 10.3 CD40LG MRAP
21 acute retinal necrosis syndrome 10.3 CD40LG MRAP
22 orthostatic proteinuria 10.3 CD79A MN1
23 iridocyclitis 10.2 CD40LG MRAP
24 epididymitis 10.2 CD40LG KLK3
25 dysentery 10.1 CD79A PHB2
26 cervicitis 10.1 CD79A MRAP MT-TG
27 plasmodium malariae malaria 10.1 CD40LG SAMHD1
28 myasthenic syndrome, congenital, 10 10.1 CD40LG MT-TG
29 panuveitis 10.1 CD40LG MRAP
30 urethral gland abscess 10.0
31 cystitis 10.0
32 chorioretinal scar 10.0 CD40LG SAMHD1
33 interstitial cystitis 9.9
34 selective igg deficiency disease 9.9 CD40LG CD79A
35 c1q nephropathy 9.9 CD40LG CD79A
36 meningovascular neurosyphilis 9.9 CD40LG CD79A
37 alpha chain disease 9.9 CD40LG CD79A
38 brill-zinsser disease 9.9 CD40LG CD79A
39 exudative glomerulonephritis 9.9 CD40LG CD79A
40 cork-handlers' disease 9.9 CD40LG CD79A
41 salpingo-oophoritis 9.9 CD40LG CD79A
42 early yaws 9.9 CD40LG CD79A
43 ventilation pneumonitis 9.9 CD40LG CD79A
44 chronic interstitial cystitis 9.9 CD40LG CD79A
45 axillary adenitis 9.9 CD40LG CD79A
46 cryofibrinogenemia 9.9 CD40LG CD79A
47 trichostrongyloidiasis 9.9 CD40LG CD79A
48 iritis 9.9 CD40LG MRAP PHB2
49 subacute bacterial endocarditis 9.9 CD40LG CD79A
50 heterophyiasis 9.9 CD40LG CD79A

Comorbidity relations with Urethral Syndrome via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Syndrome:



Diseases related to Urethral Syndrome

Symptoms & Phenotypes for Urethral Syndrome

UMLS symptoms related to Urethral Syndrome:


pain in urethra

Drugs & Therapeutics for Urethral Syndrome

Drugs for Urethral Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Cholinergic Agents
2 Cholinergic Antagonists
3 Muscarinic Antagonists
4 Neurotransmitter Agents
5 Solifenacin succinate 242478-38-2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety And Efficacy Of Solifenacin In Men With Overactive Bladder (OAB) And Detrusor Underactivity Completed NCT00441428 solifenacin

Search NIH Clinical Center for Urethral Syndrome

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: urethral diseases

Genetic Tests for Urethral Syndrome

Genetic tests related to Urethral Syndrome:

# Genetic test Affiliating Genes
1 Abnormality of the Urethra 29

Anatomical Context for Urethral Syndrome

The Foundational Model of Anatomy Ontology organs/tissues related to Urethral Syndrome:

19
The Urethra

MalaCards organs/tissues related to Urethral Syndrome:

41
Testes, Prostate, Cervix

Publications for Urethral Syndrome

Articles related to Urethral Syndrome:

(show top 50) (show all 132)
# Title Authors Year
1
Defining the Urethritis Syndrome in Men Using Patient Reported Symptoms. ( 29465655 )
2018
2
Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. ( 26760182 )
2016
3
Epidemiology and laboratory characteristics of Trichomonas vaginalis infection in Croatian men with and without urethritis syndrome: a case-control study. ( 25568091 )
2015
4
A prospective study to evaluate the efficacy of cistiquer in improving lower urinary tract symptoms in females with urethral syndrome. ( 25034330 )
2014
5
The role of a leaky epithelium and potassium in the generation of bladder symptoms in interstitial cystitis/overactive bladder, urethral syndrome, prostatitis and gynaecological chronic pelvic pain. ( 21176078 )
2011
6
The detection of urethritis pathogens among patients with the male urethritis syndrome, genital ulcer syndrome and HIV voluntary counselling and testing clients: should South Africa's syndromic management approach be revised? ( 18192290 )
2008
7
Treatment of urethral syndrome: a prospective randomized study with Nd:YAG laser. ( 16493214 )
2006
8
Urethral syndrome: response to alpha-adrenergic blocking agents. ( 16261427 )
2006
9
Treatment of post-menopausal urethral syndrome with the formula niao chang shu--a report of 40 cases. ( 15119161 )
2004
10
Dr. Li Yueqing's experience in treating female urethral syndrome. ( 15270256 )
2004
11
Electric acupuncture in the treatment of 36 cases of female urethral syndrome. ( 14719301 )
2003
12
Transabdominal vesical sonography of urethral syndrome and stress incontinence. ( 12534925 )
2003
13
Prostatitis, interstitial cystitis, chronic pelvic pain, and urethral syndrome share a common pathophysiology: lower urinary dysfunctional epithelium and potassium recycling. ( 14665339 )
2003
14
Treatment of female urethral syndrome refractory to antibiotics. ( 12402379 )
2002
15
The incidence of Chlamydia trachomatis in women with urethral syndrome. ( 11695072 )
2001
16
Azithromycin and doxycycline in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum: significance of duration of clinical symptoms. ( 11822223 )
2001
17
Intravesical potassium sensitivity in patients with interstitial cystitis and urethral syndrome. ( 11248610 )
2001
18
Duration of clinical symptoms in female patients with acute urethral syndrome caused by Chlamydia trachomatis treated with azithromycin or doxycycline. ( 11330365 )
2001
19
Comparative analysis of azithromycin and doxycycline efficacy in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum. ( 10789560 )
2000
20
Duration of clinical symptoms in female patients with acute urethral syndrome caused by Ureaplasma urealyticum treated with azithromycin or doxycycline. ( 11154040 )
2000
21
Urethral syndrome and associated risk factors related to obstetrics and gynecology. ( 10221602 )
1999
22
Equal symptomatic outcome after antibacterial treatment of acute lower urinary tract infection and the acute urethral syndrome in adult women. ( 10555247 )
1999
23
Urinary bacterial flora of women with urethral syndrome and interstitial cystitis. ( 9852391 )
1999
24
Study on acupuncture and moxibustion therapy for female urethral syndrome. ( 10437230 )
1998
25
1-day azithromycin was as effective as 7-day doxycycline for nongonococcal urethritis syndrome in men. ( 8912627 )
1996
26
Female urethral syndrome. A female prostatitis? ( 8686301 )
1996
27
Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. ( 7629982 )
1995
28
Evolving strategies for management of the nongonococcal urethritis syndrome. ( 7629989 )
1995
29
The urethral syndrome: a controlled evaluation. J Psychosom Res 1993; 37: 737-743. ( 8027965 )
1994
30
Urethral syndrome: clinical results with antibiotics alone or combined with estrogen. ( 7957464 )
1994
31
The urethral syndrome and its management. ( 7928838 )
1994
32
Fibromyalgia associated with female urethral syndrome. ( 8187451 )
1994
33
The urethral syndrome: a controlled evaluation. ( 8229904 )
1993
34
Surgical repair of hypospadias in women with symptoms of urethral syndrome. ( 1569664 )
1992
35
The urethral syndrome--why what we do works, or doesn't. ( 1479977 )
1992
36
A psychophysiological evaluation of female urethral syndrome: evidence for a muscular abnormality. ( 1625341 )
1992
37
The painful bladder: urethral syndrome and interstitial cystitis. ( 2130959 )
1990
38
Prostatodynia or painful male urethral syndrome? ( 2385883 )
1990
39
The urethral syndrome: myth or reality? A commentary. ( 2233643 )
1990
40
Genitourinary manifestations of fibrositis: an increased association with the female urethral syndrome. ( 2319522 )
1990
41
Interstitial cystitis and the urethral syndrome: a possible answer. ( 2670041 )
1989
42
Urethral syndrome. A comparison of different treatment modalities. ( 2926732 )
1989
43
Urethral syndrome: a study in psychosomatic urology. ( 2486388 )
1989
44
Cryosurgery versus dilation and massage for the treatment of recurrent urethral syndrome. ( 2810238 )
1989
45
Pharmacokinetic data and therapeutic efficacy of miocamycin: serum, urinary and prostatic levels. Therapeutic aspects in acute urethral syndrome and non-gonococcal urethritis. ( 16312542 )
1989
46
The urethral syndrome. ( 3055620 )
1988
47
Sexually transmitted diseases in women with urethral syndrome. ( 2903082 )
1988
48
The urethral syndrome. ( 3170107 )
1988
49
Efficacy of miocamycin in the therapy of non-specific genital infections (NSGI): non-gonococcal urethritis (NGU) and acute urethral syndrome (AUS). ( 3259948 )
1988
50
Urethral syndrome: patient suggestions. ( 3420419 )
1988

Variations for Urethral Syndrome

Expression for Urethral Syndrome

Search GEO for disease gene expression data for Urethral Syndrome.

Pathways for Urethral Syndrome

Pathways related to Urethral Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.19 CD40LG CD79A

GO Terms for Urethral Syndrome

Biological processes related to Urethral Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 8.62 CD40LG CD79A

Sources for Urethral Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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