MCID: URN003
MIFTS: 45

Urinary Schistosomiasis

Categories: Blood diseases, Infectious diseases, Nephrological diseases

Aliases & Classifications for Urinary Schistosomiasis

MalaCards integrated aliases for Urinary Schistosomiasis:

Name: Urinary Schistosomiasis 12 15 17 70
Schistosoma Hematobium Infection 12 70
Schistosoma Haematobium 12 15
Schistosomiasis Due to Schistosoma Haematobium 12
Schistosoma Hematobium Infectious Disease 12
Schistosoma Haematobium Infection 12
Cystitis with Bilharziasis 12
Schistosomiasis of Bladder 12
Schistosomiasis Haematobia 44
Bladder Schistosomiasis 12
Vesical Schistosomiasis 12
Schistosomiasis Urinary 54

Classifications:



External Ids:

Disease Ontology 12 DOID:1394
ICD9CM 34 120.0
MeSH 44 D012553
NCIt 50 C39294
SNOMED-CT 67 60979006
UMLS 70 C0276926 C1704430

Summaries for Urinary Schistosomiasis

Disease Ontology : 12 A schistosomiasis that involves parasitic infection of the urinary tract caused by a digenetic trematode Schistosoma haematobium causing cystitis, ureteritis, fibrosis of the bladder and haematuria, which can progress to bladder cancer.

MalaCards based summary : Urinary Schistosomiasis, also known as schistosoma hematobium infection, is related to cytokine deficiency and ascaris lumbricoides infection. An important gene associated with Urinary Schistosomiasis is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Artesunate and Mefloquine have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and bone, and related phenotypes are hematopoietic system and immune system

Related Diseases for Urinary Schistosomiasis

Diseases related to Urinary Schistosomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 467)
# Related Disease Score Top Affiliating Genes
1 cytokine deficiency 31.3 IL5 IL13
2 ascaris lumbricoides infection 30.3 IL5 IL13 IFNG
3 chlamydia 30.2 IL5 IL4 IL10 IFNG
4 lipoid nephrosis 30.2 IL13 IL10 CD80
5 buruli ulcer 30.1 IL10 IFNG
6 vaginal discharge 30.1 IL10 HP
7 bacterial infectious disease 30.0 IL10 IFNG ICOSLG CD80
8 leishmaniasis 29.9 IL5 IL4 IL13 IL10 IFNG
9 visceral leishmaniasis 29.8 IL4 IL13 IL10 IFNG
10 radiculopathy 29.8 IL5 IL13 IL10
11 schistosomiasis 29.8 STAT6 RNASE3 IL5 IL4 IL13 IL10
12 ige responsiveness, atopic 29.8 RNASE3 IL5 IL4 IL13 IL10 IGHE
13 diarrhea 29.8 IL5 IL13 IL10 IFNG
14 filariasis 29.8 IL5 IL10 IGHE IFNG CTLA4
15 trachoma 29.7 IL4 IL10 HP
16 strongyloidiasis 29.7 IL5 IL4 IL13 IGHE IFNG
17 dacryoadenitis 29.7 IL4 IL13 IL10 ICOSLG
18 onchocerciasis 29.6 RNASE3 IL5 IL4 IL13 IGHE EPX
19 filarial elephantiasis 29.6 IL5 IL4 IL13 IL10 CTLA4
20 intestinal schistosomiasis 29.6 IL5 IL4 IL13 IL10 ICOSLG
21 endomyocardial fibrosis 29.6 RNASE3 IL5 IL4 IL10 EPX
22 plasmodium falciparum malaria 29.5 IL4 IL10 IFNG HP
23 meningitis 29.4 IL5 IL4 IL13 IL10 IFNG
24 tetanus 29.4 IL5 IL4 IL13 IL10 IFNG CD80
25 human immunodeficiency virus infectious disease 29.4 IL4 IL10 IFNG ICOSLG CD80
26 disease by infectious agent 29.3 IL4 IL10 IFNG ICOSLG HP
27 urticaria 29.2 RNASE3 IL5 IL4 IL13 IL10 IGHE
28 hypereosinophilic syndrome 29.1 RNASE3 IL5 IL4 IL13 IL10 IGHE
29 parasitic helminthiasis infectious disease 28.9 STAT6 RNASE3 IL5 IL4 IL13 IL10
30 immune deficiency disease 28.8 STAT6 IL4 IL13 IL10 IFNG ICOSLG
31 malaria 28.1 STAT6 RNASE3 IL5 IL4 IL13 IL10
32 allergic disease 27.6 RNASE3 IL5 IL4 IL13 IL10 IGHE
33 asthma 27.3 STAT6 RNASE3 IL5 IL4 IL13 IL10
34 neuroschistosomiasis 11.2
35 schistosoma mansoni infection, susceptibility/ 11.2
36 proteinuria, chronic benign 10.5
37 aztreonam allergy 10.4 IL5 IL13
38 cefaclor allergy 10.4 IL5 IL13
39 cefuroxime allergy 10.4 IL5 IL13
40 exercise-induced bronchoconstriction 10.4 RNASE3 IL13
41 angioimmunoblastic lymphadenopathy with dysproteinemia 10.3 IL5 IL13
42 respiratory syncytial virus infectious disease 10.3 IL5 IL13
43 eosinophilic fasciitis 10.3 IL5 IFNG
44 b-cell growth factor 10.3 IL4 IFNG
45 neurodermatitis 10.3 IL4 IL13
46 loeffler syndrome 10.3 IL5 IL13
47 staphylococcal toxic shock syndrome 10.3 IGHE IFNG
48 carbapenem allergy 10.3 STAT6 IL13
49 urinary tract obstruction 10.3
50 orange allergy 10.3 IL5 IL13

Graphical network of the top 20 diseases related to Urinary Schistosomiasis:



Diseases related to Urinary Schistosomiasis

Symptoms & Phenotypes for Urinary Schistosomiasis

MGI Mouse Phenotypes related to Urinary Schistosomiasis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.96 CD80 CTLA4 EPX HP IFNG IL10
2 immune system MP:0005387 9.9 CD80 COLEC11 CTLA4 EPX HP IFNG
3 liver/biliary system MP:0005370 9.5 CTLA4 HP IFNG IL10 IL4 IL5
4 respiratory system MP:0005388 9.17 CTLA4 IFNG IL10 IL13 IL4 IL5

Drugs & Therapeutics for Urinary Schistosomiasis

Drugs for Urinary Schistosomiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Artesunate Approved, Investigational Phase 2, Phase 3 88495-63-0 6917864 5464098
2
Mefloquine Approved, Investigational Phase 3 53230-10-7 4046
3
Pyrimethamine Approved, Investigational, Vet_approved Phase 2, Phase 3 58-14-0 4993
4
Praziquantel Approved, Investigational, Vet_approved Phase 3 55268-74-1 4891
5 Antimalarials Phase 2, Phase 3
6 Antiprotozoal Agents Phase 2, Phase 3
7 Antiviral Agents Phase 2, Phase 3
8 Vaccines Phase 3
9 Sulfalene Phase 2, Phase 3
10 Antiparasitic Agents Phase 3
11 Anthelmintics Phase 3
12 Anti-Infective Agents Phase 3
13
Lumefantrine Approved Phase 2 82186-77-4 6437380
14
Artemether Approved Phase 2 71963-77-4 119380 9796294 68911
15
Sulfadoxine Approved, Investigational Phase 2 2447-57-6 17134
16
Pyronaridine Investigational Phase 2 74847-35-1 5485198
17 Ferroquine Phase 2
18 Artemether, Lumefantrine Drug Combination Phase 2
19 Artemisinins Phase 2
20 Artemisinine Phase 2
21 Fanasil, pyrimethamine drug combination Phase 2
22
Aluminum hydroxide Approved, Investigational Phase 1 21645-51-2
23
Aluminum sulfate Approved Phase 1 10043-01-3
24 Immunoglobulins Phase 1
25 Antibodies Phase 1
26
Ciprofloxacin Approved, Investigational 85721-33-1 2764
27
Cefuroxime Approved 55268-75-2 5361202 5479529
28
Metronidazole Approved 443-48-1 4173
29
Doxycycline Approved, Investigational, Vet_approved 564-25-0 54671203
30
Azithromycin Approved 83905-01-5 55185 447043
31 cefuroxime axetil

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 Efficacy of Chinese-made Versus WHO-PQ Praziquantel for Treatment of Schistosoma Haematobium in Zanzibar: a Randomized Controlled Trial Unknown status NCT03133832 Phase 3 Companion Tablet
2 Schistosoma Haematobium Infections Among Schoolchildren in Central Sudan One Year After Treatment With Praziquantel Completed NCT01558336 Phase 3 praziquantel
3 Safety and Efficacy of Mirazid for Schistosomiasis Treatment as Compared to Praziquantel: An Open-label Randomized Non-placebo-Controlled Study Completed NCT01529710 Phase 3 Myrrh
4 Efficacy and Safety Evaluation of the Therapeutic Vaccine Candidate Sh28GST in Association With Praziquantel (PZQ) for Prevention of Clinical and Parasitological Recurrences of S. Haematobium Infection in Children Completed NCT00870649 Phase 3
5 Randomized Double Blind Clinical Trial in Mali, Comparing the Effectiveness of Artesunate + Sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel in the Treatment of S. Haematobium in Children Completed NCT00510159 Phase 2, Phase 3 Artesunate+Sulfamethoxypyrazine/pyrimethamin;Praziquantel
6 A Proof-of-concept Trial to Evaluate Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children Completed NCT03893097 Phase 3 Praziquantel;Artesunate + Mefloquine
7 Prospective, Observational Study to Assess the Performance of CAA Measurement as a Diagnostic Tool for the Detection of Schistosoma Haematobium Infections in Pregnant Women and Their Newborn and Child in Lambaréné, Gabon Recruiting NCT03779347 Phase 3 Praziquantel
8 Evaluation of the Effect of Artemisinin-based Combination Therapies on Urinary Schistosoma Haematobium When Administered for the Treatment of Malaria Co-infection Completed NCT04264130 Phase 2 Artesunate-Pyronaridine;Artemether-Lumefantrine;Artefenomel-Ferroquine
9 Activity of Mefloquine Against Urinary Schistosomiasis Completed NCT01132248 Phase 2 Mefloquine;S/P
10 Phase 1 Study Evaluating Safety and Immunological Criteria of Efficacy of the Recombinant Vaccine Candidate Bilhvax Against Schistosomiasis Completed NCT01512277 Phase 1
11 The Influence of Transmission Season on Outcome of Schistosoma Haematobium Infection Treatment Among School Children in Urban and Peri-Urban Areas of Maputo and Matola, Mozambique Completed NCT00231322 praziquantel
12 Village Surveys of Morbidity Due to S. Haematobium for 1U01AI4547 Urinary Schistosomiasis-Determinants of Infection and Disease Completed NCT00138450
13 Study of Reproductive Health in Rural Madagascar With Emphasis on Urogenital Schistosomiasis and Sexually Transmitted Infections Completed NCT00713999 Treatment with anti-STI and anti-schistosoma regimens
14 Validation of INSPiRED Innovative Smart Diagnostic Devices for the Detection of Plasmodium Falciparum, Schistosoma Haematobium and Necator Americanus at CERMEL, Gabon. Recruiting NCT04505046
15 Prevention of HIV and Improved Diagnosis of Adolescent Genital Disease in Bilharzia Endemic KwaZulu-Natal, South Africa Recruiting NCT01154907 Praziquantel

Search NIH Clinical Center for Urinary Schistosomiasis

Cochrane evidence based reviews: schistosomiasis haematobia

Genetic Tests for Urinary Schistosomiasis

Anatomical Context for Urinary Schistosomiasis

MalaCards organs/tissues related to Urinary Schistosomiasis:

40
Skin, Kidney, Bone, Heart, Lung, Prostate, Spleen

Publications for Urinary Schistosomiasis

Articles related to Urinary Schistosomiasis:

(show top 50) (show all 856)
# Title Authors PMID Year
1
Eosinophils, eosinophil cationic protein and eosinophil-derived neurotoxin in serum and urine of patients with onchocerciasis coinfected with intestinal nematodes and in urinary schistosomiasis. 54 61
10206116 1999
2
Diagnosis of female genital schistosomiasis by indirect disease markers: determination of eosinophil cationic protein, neopterin and IgA in vaginal fluid and swab eluates. 54 61
9028411 1996
3
Morbidity markers for Schistosoma haematobium infection. 54 61
7825227 1994
4
Indirect assessment of eosinophiluria in urinary schistosomiasis using eosinophil cationic protein (ECP) and eosinophil protein X (EPX). 61 54
8103623 1993
5
Two Case Reports of Urinary Schistosomiasis in Adopted Children. 61
33165277 2021
6
Transmission sites for Schistosoma haematobium and Schistosoma bovis identified in localities within the Athi River basin of Kenya using a PCR-RFLP assay. 61
33644442 2021
7
Urogenital Schistosomiasis among Primary School Children in Rural Communities in Obudu, Southern Nigeria. 61
33614224 2021
8
Knowledge and perceptions of schistosomiasis, a water-borne disease, in two semi-arid rural areas of South Africa (Ndumo) and Zimbabwe (Ntalale). 61
33251346 2020
9
Influence of human-surface water interactions on the transmission of urinary schistosomiasis in the Lower Densu River basin, Ghana. 61
33277069 2020
10
Urinary schistosomiasis and the associated bladder cancer: update. 61
33252773 2020
11
Snail Fever of the Bladder in a Non-endemic Area. 61
32893804 2020
12
Malaria coinfection with Neglected Tropical Diseases (NTDs) in children at Internally Displaced Persons (IDP) camp in Benin City, Nigeria. 61
32793830 2020
13
Three monthly doses of 60 mg/kg praziquantel for Schistosoma haematobium infection is a safe and effective treatment regimen. 61
32375658 2020
14
Narrow band imaging in the diagnosis of bladder schistosomiasis. 61
32269048 2020
15
Integrated community-based intervention for urinary schistosomiasis and soil-transmitted helminthiasis in children from Caxito, Angola. 61
31290969 2020
16
Will Nigerians Win the War Against Urinary Schistosomiasis? Prevalence, Intensity, Risk Factors and Knowledge Assessment among Some Rural Communities in Southwestern Nigeria. 61
32079189 2020
17
Case Report of Urinary Schistosomiasis in a Returned Traveler in Korea. 61
32145727 2020
18
Retraction Note: The epidemiology and chemotherapeutic approaches to the control of urinary schistosomiasis in school-age children (SAC): a systematic review. 61
32005106 2020
19
Prevalence of urinary schistosomiasis amongst primary school children in Ikwo and Ohaukwu Communities of Ebonyi State, Nigeria. 61
32934908 2020
20
Review of the Urinary Schistosomiasis Control in Morocco (1960-2018). 61
33123194 2020
21
Massive Bilateral Hydroureteronephrosis and End-Stage Renal Disease Ensuing From Chronic Schistosomiasis: A Case Report. 61
32131640 2020
22
Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings. 61
31735956 2020
23
Acceptability and feasibility of genital self-sampling for the diagnosis of female genital schistosomiasis: a cross-sectional study in Zambia. 61
33154978 2020
24
The usefulness of indirect diagnostic tests for Schistosoma haematobium infection after repeated rounds of mass treatment with praziquantel in Mpwapwa and Chakechake districts in Tanzania. 61
31693938 2020
25
Haemostatic changes in urogenital schistosomiasis haematobium: a case-control study in Gabonese schoolchildren. 61
31500673 2019
26
Urinary schistosomiasis in migrant population: a case series from a single centre in southern Italy. 61
30377953 2019
27
Community knowledge, perceptions and water contact practices associated with transmission of urinary schistosomiasis in an endemic region: a qualitative cross-sectional study. 61
31174505 2019
28
Evaluation of the Clinitek®, a point-of-care urinalysis system for the measurement of clinically significant urinary metabolites and detection of haematuria in Schistosoma haematobium infected children in southern Côte d'Ivoire. 61
31196145 2019
29
Supplementation with micronutrients and schistosomiasis: systematic review and meta-analysis. 61
30983544 2019
30
Corrigendum: Mapping of Urinary Schistosomiasis in Anambra State, Nigeria. 61
31148439 2019
31
Epidemiological Survey on Schistosomiasis and Intestinal Helminthiasis among Village Residents of the Rural River Basin Area in White Nile State, Sudan. 61
31104405 2019
32
Mapping of Urinary Schistosomiasis in Anambra State, Nigeria. 61
30951269 2019
33
Urinary schistosomiasis in Ebonyi State, Nigeria from 2006 to 2017. 61
31397382 2019
34
Human schistosomiasis in Benin: Countrywide evidence of Schistosoma haematobium predominance. 61
30633895 2019
35
Schistosoma haematobium causing pulmonary schistosomiasis in a returning traveller. 61
30852514 2019
36
Parasitic Hematuria: Six Cases in a Row in a Single Centre in Spain. 61
29059677 2019
37
Cytological and Wet Mount Microscopic Observations Made in Urine of Schistosoma haematobium-Infected Children: Hint of the Implication in Bladder Cancer. 61
31565106 2019
38
Urinary schistosomiasis in Nigeria: a 50 year review of prevalence, distribution and disease burden. 61
30943149 2019
39
The epidemiology and chemotherapeutic approaches to the control of urinary schistosomiasis in school-age children (SAC): a systematic review. 61
30658583 2019
40
Maternal malaria but not schistosomiasis is associated with a higher risk of febrile infection in infant during the first 3 months of life: A mother-child cohort in Benin. 61
31536589 2019
41
Prevalence and factors associated with renal dysfunction among children with sickle cell disease attending the sickle cell disease clinic at a tertiary hospital in Northwestern Tanzania. 61
31211789 2019
42
Phylogeography of Bulinus truncatus (Audouin, 1827) (Gastropoda: Planorbidae) in Selected African Countries. 61
30572694 2018
43
Safety and efficacy of the rSh28GST urinary schistosomiasis vaccine: A phase 3 randomized, controlled trial in Senegalese children. 61
30532268 2018
44
Urinary schistosomiasis in Boko Haram-related internally displaced Nigerian children. 61
30588972 2018
45
Ultrasound Evolution of Pediatric Urinary Schistosomiasis after Treatment with Praziquantel in a Highly Endemic Area. 61
30141396 2018
46
Human papillomavirus and squamous cell carcinoma of the urinary bladder: DaBlaCa-10 study. 61
30526165 2018
47
Sonographic early findings in a case of bladder schistosomiasis. 61
30003454 2018
48
High Efficacy of Praziquantel in Schistosoma haematobium-Infected Children in Taraba State, Northeast Nigeria: A follow-up study. 61
30607270 2018
49
Urinary schistosomiasis presented as bladder malignancy with pulmonary metastases: a case report. 61
29962297 2018
50
Infection status and risk factors associated with urinary schistosomiasis among school-going children in the Ndumo area of uMkhanyakude District in KwaZulu-Natal, South Africa two years post-treatment. 61
29679769 2018

Variations for Urinary Schistosomiasis

Expression for Urinary Schistosomiasis

Search GEO for disease gene expression data for Urinary Schistosomiasis.

Pathways for Urinary Schistosomiasis

Pathways related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

(show all 34)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.62 STAT6 RNASE3 IL5 IL4 IL13 IL10
2
Show member pathways
13.43 STAT6 IL5 IL4 IL13 IL10 IFNG
3
Show member pathways
13.3 STAT6 IL5 IL4 IL13 IL10 IGHE
4 12.75 STAT6 IL5 IL4 IL13 IFNG
5
Show member pathways
12.6 IL4 IL10 IGHE IFNG ICOSLG CD80
6
Show member pathways
12.56 STAT6 IL5 IL4 IL13 IL10 IFNG
7
Show member pathways
12.55 IL5 IL4 IL10 IFNG CTLA4
8 12.51 STAT6 IL4 IL10 IFNG CTLA4
9
Show member pathways
12.49 IL5 IL4 IL13 IGHE
10
Show member pathways
12.4 RNASE3 IL5 IL4 IL13 IL10 IFNG
11
Show member pathways
12.37 STAT6 IL5 IL4 IL13 IL10 IFNG
12
Show member pathways
12.25 IL5 IL4 IL13 IFNG
13
Show member pathways
12.21 IL5 IL4 IL13 IL10 IFNG
14 11.99 IL5 IL4 IL10 IFNG CD80
15 11.97 STAT6 IL4 IL13 IL10 IGHE
16
Show member pathways
11.89 STAT6 IL4 IFNG
17 11.8 IL5 IL4 IL13 IFNG
18 11.79 IFNG CTLA4 CD80
19
Show member pathways
11.78 IL4 IFNG CD80
20
Show member pathways
11.76 IL5 IL4 IFNG CTLA4
21 11.73 IL5 IL4 IL13 IL10 IFNG
22
Show member pathways
11.69 IL10 IFNG CD80
23 11.62 IL5 IL4 IL10 ICOSLG CTLA4
24 11.6 IL5 IL4 IL13
25 11.57 STAT6 IL5 IL4 IL10 IGHE
26 11.53 IL4 IL13 IL10 CD80
27 11.3 IL5 IL4 IFNG CD80
28 11.26 IL5 IL4 IL13 IFNG
29 11.18 IL5 IL4 IL13 IL10 IFNG
30 11.07 IL5 IL4 IL13 IL10 IFNG
31 10.93 IL5 IL4 IL13 IL10 CD80
32 10.89 STAT6 IL4
33 10.83 STAT6 IL5 IL4 IL13 IL10 IFNG
34 10.81 IL5 IL4 IL13

GO Terms for Urinary Schistosomiasis

Cellular components related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.65 RNASE3 IL5 IL4 IL13 IL10 IFNG
2 external side of plasma membrane GO:0009897 9.55 IL13 IGHE ICOSLG CTLA4 CD80
3 extracellular region GO:0005576 9.36 RNASE3 IL5 IL4 IL13 IL10 IGHE
4 protein complex involved in cell adhesion GO:0098636 9.26 CTLA4 CD80

Biological processes related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 10.01 IGHE ICOSLG HP FCN2 CTLA4 COLEC11
2 negative regulation of inflammatory response GO:0050728 9.81 IL4 IL13 IL10
3 defense response GO:0006952 9.8 STAT6 ICOSLG HP EPX
4 positive regulation of cold-induced thermogenesis GO:0120162 9.78 STAT6 IL4 IL13
5 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.76 IL4 IL13 IFNG
6 T cell costimulation GO:0031295 9.72 ICOSLG CTLA4 CD80
7 defense response to bacterium GO:0042742 9.72 RNASE3 IL10 IGHE HP EPX
8 negative regulation of T cell proliferation GO:0042130 9.7 IL10 CTLA4 CD80
9 positive regulation of B cell proliferation GO:0030890 9.69 IL5 IL4 IL13
10 positive regulation of macrophage activation GO:0043032 9.64 IL13 IL10
11 negative regulation of B cell proliferation GO:0030889 9.63 IL10 CTLA4
12 regulation of regulatory T cell differentiation GO:0045589 9.62 IFNG CTLA4
13 positive regulation of signaling receptor activity GO:2000273 9.62 IL10 IFNG
14 macrophage activation GO:0042116 9.61 IL4 IL13
15 complement activation, lectin pathway GO:0001867 9.6 FCN2 COLEC11
16 positive regulation of mast cell degranulation GO:0043306 9.59 IL4 IL13
17 positive regulation of cellular respiration GO:1901857 9.58 IL4 IFNG
18 negative regulation of endothelial cell apoptotic process GO:2000352 9.58 IL4 IL13 IL10
19 neuroinflammatory response GO:0150076 9.57 IL4 IFNG
20 type 2 immune response GO:0042092 9.56 IL4 IL10
21 microglial cell activation GO:0001774 9.54 IL4 IL13 IFNG
22 cytokine-mediated signaling pathway GO:0019221 9.5 STAT6 IL5 IL4 IL13 IL10 IGHE
23 negative regulation of complement-dependent cytotoxicity GO:1903660 9.48 IL4 IL13
24 positive regulation of isotype switching to IgE isotypes GO:0048295 9.46 STAT6 IL4
25 regulation of isotype switching GO:0045191 9.43 IL4 IL10
26 positive regulation of immunoglobulin production GO:0002639 9.43 IL5 IL13 IL10
27 positive regulation of MHC class II biosynthetic process GO:0045348 9.33 IL4 IL10 IFNG
28 immune response GO:0006955 9.23 IL5 IL4 IL13 IL10 IGHE IFNG

Molecular functions related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IL5 IL4 IL13 IL10 IFNG

Sources for Urinary Schistosomiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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