Urinary Tract Infection (UTI)

Categories: Infectious diseases, Nephrological diseases
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Aliases & Classifications for Urinary Tract Infection

Summaries for Urinary Tract Infection

MedlinePlus: 41 The urinary system is the body's drainage system for removing wastes and extra water. It includes two kidneys, two ureters, a bladder, and a urethra. Urinary tract infections (UTIs) are the second most common type of infection in the body. You may have a UTI if you notice: Pain or burning when you urinate Fever, tiredness, or shakiness An urge to urinate often Pressure in your lower belly Urine that smells bad or looks cloudy or reddish Pain in your back or side below the ribs People of any age or sex can get UTIs. But about four times as many women get UTIs as men. You're also at higher risk if you have diabetes, need a tube to drain your bladder, or have a spinal cord injury. If you think you have a UTI it is important to see your doctor. Your doctor can tell if you have a UTI with a urine test. Treatment is with antibiotics. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary: Urinary Tract Infection, also known as urinary tract infections, is related to acute cystitis and cystitis. An important gene associated with Urinary Tract Infection is EBF3 (EBF Transcription Factor 3), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Spinal cord injury. The drugs Piperacillin and Ceftriaxone have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, kidney and prostate, and related phenotype is cardiovascular system.

Disease Ontology: 11 An urinary system disease that is characterized by an infection in any part of the urinary system, including the kidneys, ureters, bladder or urethra.

Wikipedia: 75 A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects... more...

Related Diseases for Urinary Tract Infection

Diseases in the Urinary Tract Infection family:

Urinary Tract Infections, Recurrent

Diseases related to Urinary Tract Infection via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1344)
# Related Disease Score Top Affiliating Genes
1 acute cystitis 33.1 UPK1A UMOD LCN2 IL6 CXCL8
2 cystitis 32.9 UPK1A UMOD TNF IL6 CXCL8 CRP
3 bacteriuria 32.9 UMOD IL6 CXCL8 CRP ALB
4 pyuria 32.7 LCN2 KLK3 IL6 CRP ALB
5 pyelonephritis 32.3 UMOD TNF LCN2 IL6 CXCL8 CRP
6 urethral syndrome 32.3 TNF KLK3 IL6 CXCL8 CRP
7 vesicoureteral reflux 32.3 UPK1A UMOD LCN2 EBF3 CXCL8 CRP
8 ureteral disease 32.2 UMOD TNF LCN2 IL6 CCR6 ALB
9 acute pyelonephritis 31.9 VIM UBAC1 TNF LCN2 IL6 CXCL8
10 neurogenic bladder 31.9 UPK1A KLK3 INS EBF3 CRP ALB
11 hydronephrosis 31.8 LCN2 KLK3 IL6 CXCL8 CRP ALB
12 urolithiasis 31.8 UMOD IL6 HOGA1 ALB
13 chronic pyelonephritis 31.7 UMOD CRP ALB
14 klebsiella pneumonia 31.6 CRP ALB
15 toxic shock syndrome 31.6 TNF IL6 CXCL8 CRP
16 urinary tract obstruction 31.6 UMOD TNF LCN2 KLK3 IL6 CRP
17 prostatitis 31.5 TNF KLK3 IL6 CXCL8
18 diarrhea 31.5 TNF IL6 CXCL8 ALB
19 pneumonia 31.4 TNF IL6 CXCL8 CRP ALB
20 urinary system disease 31.4 UMOD KLK3 CCR6 ALB
21 chronic kidney disease 31.4 UMOD TNF LCN2 INS IL6 CRP
22 bowel dysfunction 31.3 TNF LCN2 INS IL6 CRP ALB
23 endocarditis 31.3 TNF LCN2 IL6 CXCL8 CRP ALB
24 vaginitis 31.3 TNF IL6 CXCL8 CCR6
25 interstitial cystitis 31.3 UPK1A TNF IL6
26 haemophilus influenzae 31.3 TNF CXCL8
27 liver cirrhosis 31.3 TNF INS IL6 ALB
28 kidney disease 31.3 UMOD TNF LCN2 INS IL6 CXCL8
29 chlamydia 31.3 TNF IL6 CXCL8 CRP
30 meningitis 31.3 TNF IL6 CXCL8 CRP ALB
31 osteomyelitis 31.3 TNF IL6 CXCL8 CRP
32 nutritional deficiency disease 31.3 IL6 CRP CCR6 ALB
33 sickle cell anemia 31.3 TNF IL6 CRP ALB
34 bilirubin metabolic disorder 31.2 TNF INS IL6 CXCL8 CRP ALB
35 vaginal discharge 31.2 TNF IL6 CXCL8 CRP ALB
36 urethritis 31.2 TNF KLK3 IL6 CXCL8 CRP CD248
37 bacterial meningitis 31.2 TNF CXCL8 CRP
38 prostatic hypertrophy 31.2 KLK3 INS CRP ALB
39 cerebrovascular disease 31.2 TNF INS IL6 CRP CCR6 ALB
40 gastroenteritis 31.2 TNF IL6 CXCL8 CRP ALB
41 pre-eclampsia 31.2 TNF INS IL6 CXCL8 CRP ALB
42 ureterolithiasis 31.1 KLK3 CRP ALB
43 deficiency anemia 31.1 TNF INS IL6 CRP CCR6 ALB
44 congestive heart failure 31.1 TNF INS IL6 ALB
45 autoimmune disease 31.1 TNF INS IL6 CRP CCR6
46 adult syndrome 31.1 TNF INS IL6 CRP
47 bacterial vaginosis 31.1 TNF IL6 CXCL8 CCR6
48 acute kidney failure 31.1 UMOD LCN2 IL6 ALB
49 peritonitis 31.1 TNF LCN2 IL6 CXCL8 CRP ALB
50 polycystic kidney disease 31.1 UMOD TNF LCN2 INS CRP ALB

Graphical network of the top 20 diseases related to Urinary Tract Infection:

Diseases related to Urinary Tract Infection

Symptoms & Phenotypes for Urinary Tract Infection

MGI Mouse Phenotypes related to Urinary Tract Infection:

# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.4 ALB CCR6 CRP IL6 INS KLK3

Drugs & Therapeutics for Urinary Tract Infection

Drugs for Urinary Tract Infection (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 361)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Piperacillin Approved Phase 4 66258-76-2 43672
Ceftriaxone Approved Phase 4 73384-59-5 5479530
Cefixime Approved, Investigational Phase 4 79350-37-1 5362065
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1, 93107-08-5 2764
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
Sulbactam Approved Phase 4 68373-14-8 5316
Doripenem Approved, Investigational Phase 4 148016-81-3 73303
Ibuprofen Approved Phase 4 15687-27-1 3672
Zinc cation Approved, Experimental, Investigational Phase 4 7440-66-6, 23713-49-7 32051
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 10909430
Framycetin Approved, Experimental, Vet_approved Phase 4 1404-04-2, 119-04-0, 3947-65-7 413349 8378
Vancomycin Approved Phase 4 1404-90-6 14969
Belladonna Approved, Experimental Phase 4
Methylene blue Approved, Investigational Phase 4 61-73-4 6099
15 Apricot Approved Phase 4
Cefadroxil Approved, Vet_approved, Withdrawn Phase 4 66592-87-8, 50370-12-2 47965
Lactitol Approved, Investigational Phase 4 585-86-4 157355
Halofantrine Approved Phase 4 69756-53-2 37393
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
Methyltestosterone Approved Phase 4 58-18-4 6010
Testosterone undecanoate Approved, Investigational Phase 4 5949-44-0 21873174 65157
Testosterone enanthate Approved Phase 4 315-37-7 9416
Testosterone Approved, Investigational Phase 4 58-22-0 5408 6013
Clindamycin Approved, Vet_approved Phase 4 18323-44-9, 24729-96-2 29029
Avibactam Approved Phase 4 1192500-31-4
Colistin Approved Phase 4 1264-72-8, 1066-17-7 5311054
Tigecycline Approved Phase 4 220620-09-7 5282044
Benzylpenicillin Approved, Vet_approved Phase 4 61-33-6 5904
Procaine Approved, Investigational, Vet_approved Phase 4 59-46-1 4914
Metronidazole Approved Phase 4 443-48-1, 69198-10-3 4173
32 Sugarcane Approved Phase 4
Linezolid Approved, Investigational Phase 4 165800-03-3 441401
Tetracycline Approved, Vet_approved, Withdrawn Phase 4 60-54-8 5353990
Amikacin Approved, Investigational, Vet_approved Phase 4 37517-28-5, 39831-55-5 37768
Cephalexin Approved, Investigational, Vet_approved Phase 4 15686-71-2 27447
Tobramycin Approved, Investigational Phase 4 32986-56-4 36294
Fosfomycin Approved Phase 4 23155-02-4 446987
Imipenem Approved Phase 4 74431-23-5, 64221-86-9 104838
Cilastatin Approved, Investigational Phase 4 82009-34-5 6435415
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
Ofloxacin Approved Phase 4 82419-36-1 4583
Iodine Approved, Investigational Phase 4 7553-56-2 807
Povidone-iodine Approved Phase 4 25655-41-8
Povidone K30 Approved, Experimental, Withdrawn Phase 4 9003-39-8 6917 131751496
Cefoxitin Approved Phase 4 35607-66-0 441199
Cefotaxime Approved Phase 4 63527-52-6 5742673 456256
Cathine Approved, Experimental, Illicit, Vet_approved, Withdrawn Phase 4 14838-15-4, 492-39-7 131954576 4786 26934
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
Norfloxacin Approved Phase 4 70458-96-7 4539

Interventional clinical trials:

(show top 50) (show all 607)
# Name Status NCT ID Phase Drugs
1 Randomised Clinical Trial Comparing Fosfomycin vs. Nitrofurantoin for Treatment of Uncomplicated Lower Urinary Tract Infection in Female Adults at Increased Risk of Antibiotic-resistant Bacterial Infection Unknown status NCT01966653 Phase 4 nitrofurantoin;fosfomycin
2 Efficacy of Temocillin in Urinary Tract Infection Due to ESBL Producing and AmpC Hyperproducing Enterobacteriaceae Unknown status NCT02681263 Phase 4 Temocillin
3 A Open Multi-center Clinical Study on Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
4 The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Symptomatic Non-complicated Urinary Tract Infection in Females Unknown status NCT02094703 Phase 4 Levofloxacin;Solifenacin succinate;Placebo (for Solifenacin succinate)
5 Randomized Placebo-Controlled Trial of Gentamicin Bladder Instillation for the Prevention of Urinary Tract Infection in Adults at High Risk for Cystitis Due to Intermittent Catheterization Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
6 Safety and Efficacy of Fixed-low-dose Amikacin for Urinary Tract Infection on the Elderly Patient Unknown status NCT04197739 Phase 4 Amikacin
7 Sanjin Tablets for the Treatment of Acute Simple Lower Urinary Tract Infection and Its Influence on Recurrence Rate: a Randomized, Double Blind, Parallel Control of Positive Drugs, Multi-center Clinical Study Unknown status NCT03658291 Phase 4 Sanjin tablets;Sanjin tablets simulants;Levofloxacin
8 Low Dose Estriol With Lactobacilli (Gynoflor) Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized, Open, Parallel-Group Study Unknown status NCT00900653 Phase 4 Gynoflor E (low dose estriol with lactobacillus)
9 The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients Unknown status NCT02113774 Phase 4
10 Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit Unknown status NCT02032394 Phase 4 Povidone-iodine;Chlorhexidine;Normal saline
11 An Open Label Non Placebo Study to Evaluate Efficacy and Safety of Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections Unknown status NCT03160807 Phase 4 Levofloxacin
12 A Randomised, Double-blind, Placebo Controlled Trial Evaluating the Effectiveness of a Cranberry Concentrate (CranrichTM) in Preventing Recurrent Urinary Tract Infections in Adult Women Unknown status NCT02454309 Phase 4
13 Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic Urinary Tract Infections Due to Extended-spectrum β-lactamase (ESBL)-Producing Escherichia Coli or Klebsiella Pneumoniae - (CAPITIS Study) Unknown status NCT03891433 Phase 4 Meropenem;Ertapenem 1000 MG;Piperacillin, Tazobactam 4-0.5G Solution for Injection
14 Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a History of Upper Urinary Tract Infections:a Multicentre Randomised Study Unknown status NCT00156546 Phase 4 antibiotic to reduce the recurrence of infection
15 Noroxin Efficacy and Safety Trial Unknown status NCT03506256 Phase 4 Norfloxacin 400 MG
16 Recurrent Urinary Tract Infections in Children: Bacterial Identification, Antibiotic Susceptibility Profiling and Cytokine Levels Associated With Antibiotic Prophylaxis Completed NCT02357758 Phase 4 Antibiotic Prophylaxis
17 Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (NAUTICA): A Randomized Controlled Trial Completed NCT03287089 Phase 4 Nitrofurantoin 100 MG;Placebo Oral Tablet
18 Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population With Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort Trial Comparing Short (7 Days) Antibiotic Treatment With Conventional Treatment (14 Days) Completed NCT00809913 Phase 4 short treatment (ciprofloxacin)
19 The Bacteriuria in Renal Transplantation (BiRT) Study: A Prospective, Randomized, Parallel-group, Multicenter, Open-label, Superiority Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria Completed NCT01871753 Phase 4
20 Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized Clinical Trial Completed NCT01958073 Phase 4 Conjugated Estrogen Vaginal Cream;Estradiol Ring;Placebo
21 Introduction of Nitrofurantoin in Place of Ciprofloxacin in Patients of Uncomplicated Urinary Tract Infection: a Controlled Clinical Trial to Establish the Relationship Between Revival and Associated Shift in Sensitivity Pattern of the Causative Microbes Completed NCT03716804 Phase 4 Tablet Nitrofurantoin;Tablet Ciprofloxacin/ Tablet Cefixime/ Tablet Cefuroxime
22 Does Prophylaxis With Macrobid Reduce the Incidence of Urinary Tract Infection in Patients Who Receive a Sub-Urethral Sling for the Treatment of Stress Urinary Incontinence: Randomized, Double Blinded Placebo Controlled Clinical Trial Completed NCT00734968 Phase 4 Nitrofurantoin
23 Clinical and Microbiologic Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection in Adult Women. Completed NCT03366207 Phase 4 Ciprofloxacin
24 Perioperative Disodium Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients. Controlled Clinical Trial (PERIFOS Trial) Completed NCT03235947 Phase 4 Fosfomycin disodium;Trimethoprim / Sulfamethoxazole;Intravenous placebo
25 Reducing Antibiotic Use for Uncomplicated Urinary Tract Infection in General Practice by Treatment With Uva Ursi (UU)- a Comparative Effectiveness Trial Completed NCT03151603 Phase 4 Arctuvan;Fosfomycin;Placebo to Arctuvan;Placebo to Fosfomycin
26 Open Label Study on the Bacteriological and Clinical Efficacy and Safety of a Nitrofurantoin Formulation Given Twice Daily (Bid) for Seven Days in Uncomplicated Urinary Tract Infection in Adults Completed NCT01092351 Phase 4 Nitrofurantoin
27 A Randomized, Multicenter, Parallel Group Study to Evaluate Safety and Efficacy of a Weekly Oral Cyclic Antibiotic Programme in the Prevention of Urinary Tract Infection on Neurological Bladder Completed NCT01388413 Phase 4 Weekly Oral Cyclic Antibiotic programme
28 Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - a Comparative Effectiveness Study in General Practice (ICUTI) Completed NCT01488955 Phase 4 Ibuprofen;Fosfomycin-Trometamol
29 Antibiotic Prophylaxis for Urinary Tract Infection in Patients Requiring Catheterization After Urogynecologic Surgery Completed NCT01450800 Phase 4 Nitrofurantoin;Placebo
30 Comparison of Methods for Prevention of Urinary Tract Infection Following Botox Injection: a Non-Inferiority Trial Completed NCT03508921 Phase 4 Extended Antibiotics
31 Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation. Randomized Controlled Trial. Completed NCT01820897 Phase 4 Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
32 Prospective, Open Label Non-comparative, Multi-center Trial to Evaluate the Efficacy and Safety of Cipro® XR 500 mg Once Daily for 3 Days in Treating Female Patients With Acute, Uncomplicated, Symptomatic Lower Urinary Tract Infections Completed NCT00669994 Phase 4 Ciprofloxacin
33 Cipro® XR Excellence in Therapeutic Response and Activity (eXtRa) - Assessing Symptom Relief in Urinary Tract Infections Completed NCT00676533 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
34 Pharmacokinetics of Ciprofloxacin in Pediatric Patients With Emphasis on Renal Excretion Completed NCT02598362 Phase 4 ciprofloxacin
35 Use of Standardized Delegation Form in Diagnosing and Treating Acute Cystitis in Primary Care Facilities. Completed NCT01132131 Phase 4
36 Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial Completed NCT00126698 Phase 4 trimethoprim-sulfamethoxazole;ciprofloxacin
37 Randomized Controled Multicentric Trial, of Non Inferiority, Comparing Two Durations of Antibiotherapy (5 Days Versus 10 Days) in COMMUNAUTARY Acute Uncomplicated Pyelonephritis. Completed NCT00873626 Phase 4 levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
38 A Randomized, Controlled, Multicentre Trial of Collateral Damage on the Intestinal Microbiota Inferred by Temocillin Versus Cefotaxime in Patients Receiving Empirical Treatment for Febrile Urinary Tract Infections Completed NCT02959957 Phase 4 Temocillin;Cefotaxime
39 Antibiotic Prophylaxis After Acute Pyelonephritis for Prevention of Urinary Tract Infections in Children With Vesico-Ureteral Reflux. Completed NCT00382343 Phase 4 Sulfamethoxazole/trimethoprim
40 Prospective, Open-Label, Noncomparative, Multicenter Study to Evaluate the Efficacy and Safety of Ciprofloxacin Extended Release (Cipro XR) 1000 mg Tablets Given Once Daily for 7 to 14 Days in the Treatment of Patients 18 Years or Older With Complicated Urinary Tract Infections Caused by Pseudomonas Aeruginosa and Other Common Uropathogens Completed NCT00481689 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
41 A Post Marketing Surveillance Study on the Safety and Effectiveness of Doripenem in the Therapy of Thai Patients With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Complicated Urinary Tract Infections Completed NCT00965848 Phase 4 Doripenem
42 Evaluation of Suprapubic Noble Metal Alloy BIP Foley Catheter in the Prevention of Catheter-associated Urinary Tract Infections in Spinal Cord Injured Patients Completed NCT02808000 Phase 4
43 Antibiotic Treatment for Intermittent Bladder Catheterisation: A Randomised Controlled Trial of Once Daily Prophylaxis Completed NCT02145338 Phase 4 Nitrofurantoin or Trimethoprim or Cefalexin
44 EXPRESS: Evaluating Cipro XR Patient Response, Education, Safety, and Satisfaction Completed NCT00663806 Phase 4
45 Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Infection: A Randomized Controlled Study Completed NCT03099863 Phase 4 Cystoscopic Fluid containing Neosporin G. U. Irrigant;Cystoscopic Fluid/Placebo
46 The Efficacy and Safety of Pivmecillinam in Treating Bacteriemic Urosepsis Caused by E.Coli Completed NCT03282006 Phase 4 pivmecillinam
47 Methenamine Hippurate Versus Trimethoprim in the Prevention of Recurrent UTIs Completed NCT03077711 Phase 4 Trimethoprim;Methenamine hippurate
48 The EDGE Consortium: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy: Part 1 Completed NCT02384200 Phase 4 nitrofurantoin monohydrate/macrocrystalline capsules;ampicillin;gentamicin;vancomycin;ceftriaxone
49 Efficacy and Safety of CRO-SBT Performed in Children With Acute Bacterial Infection Completed NCT04066621 Phase 4 Ceftriaxone Sodium and Sulbactam Sodium for Injection
50 A Prospective Study on the Usage Patterns of Doripenem in the Asia Pacific Region Completed NCT00986102 Phase 4 doripenem

Search NIH Clinical Center for Urinary Tract Infection

Cochrane evidence based reviews: urinary tract infections

Genetic Tests for Urinary Tract Infection

Anatomical Context for Urinary Tract Infection

Organs/tissues related to Urinary Tract Infection:

MalaCards : Spinal Cord, Kidney, Prostate, Neutrophil, Liver, Whole Blood, Skin

Publications for Urinary Tract Infection

Articles related to Urinary Tract Infection:

(show top 50) (show all 46002)
# Title Authors PMID Year
A post-trial follow-up study of pentosan polysulfate monotherapy on preventing recurrent urinary tract infection in women. 62 41
36202908 2022
Femistina versus Canephron as a prevention of urinary tract infections after midurethral sling surgery - Non-inferiority study. 62 41
36027670 2022
Effect of Educational intervention based on Health Belief Model on promoting preventive behaviours of urinary tract infections in mothers with children under 6-Years of age. 62 41
36199084 2022
Whole-genome sequencing of patients with rare diseases in a national health system. 5
32581362 2020
Rapid, direct, visualized and antibody-free bacterial detection with extra species identification and susceptibility evaluation capabilities. 62
36436466 2023
Neurocritical Care Aspects of Ischemic Stroke Management. 62
36333037 2023
Immobilization of poly-L-lysine brush via surface initiated polymerization for the development of long-term antibacterial coating for silicone catheter. 62
36399903 2023
Retrospective Comparison of Cefdinir, Cephalexin, and Sulfamethoxazole-Trimethoprim in the Treatment of Outpatient Pediatric Urinary Tract Infections. 62
35861216 2023
Fast identification and susceptibility determination of E. coli isolated directly from patients' urine using infrared-spectroscopy and machine learning. 62
36170776 2023
What are the risk factors for recurrent UTI with repeated ESBL-producing Enterobacteriaceae? A retrospective cohort study. 62
36195248 2023
Effects of aging on urinary tract epithelial homeostasis and immunity. 62
36368522 2023
Interactions of microorganisms within a urinary catheter polymicrobial biofilm model. 62
36123299 2023
Distribution and expression of virulence genes (hlyA, sat) and genotyping of Escherichia coli O25b/ST131 by multi-locus variable number tandem repeat analysis in Tehran, Iran. 62
36129793 2022
Spinal infection with intraspinal abscess or empyema and acute myelopathy: comparative analysis of diagnostics, therapy, complications and outcome in primary care. 62
35657387 2022
Racial Differences in Urine Testing of Febrile Young Children Presenting to Pediatric Hospitals. 62
34780020 2022
Effectiveness of herbal medicines to prevent and control symptoms of urinary tract infections and to reduce antibiotic use: A literature review. 62
36345487 2022
Distribution of virulence determinants among Escherichia coli ST131 and its H30/H30-Rx subclones in Turkey. 62
36459132 2022
Intracellular uropathogenic Escherichia coli are undetectable in urinary bladders after oral mecillinam treatment: An experimental study in a pig model of cystitis. 62
36244593 2022
Voided Volume for Assessment of Bladder Emptying After Female Pelvic Floor Surgery: A Randomized Controlled Trial. 62
36409638 2022
Minimally Invasive Lower Anterior Resections - Better than Open But Not All the Same. 62
36469507 2022
Pharmacokinetic, Safety, and Tolerability Evaluations of Gepotidacin (GSK2140944) in Healthy Japanese Participants. 62
36468634 2022
Heart Failure is Associated with Early Medical and Surgery-related Complications Following THA: A Propensity-Scored Analysis. 62
36470365 2022
Development and validation of models for detection of postoperative infections using structured electronic health records data and machine learning. 62
36470694 2022
Drug synergy discovery of tavaborole and aminoglycosides against Escherichia coli using high throughput screening. 62
36454354 2022
Clean-catching urine from pigs: A method for collecting quality specimens for urinalysis and microbiological culturing in a laboratory environment. 62
36457157 2022
Upper or lower tract approach for duplex anomalies? A bi-institutional comparative analysis of robot-assisted approaches. 62
35079941 2022
Association between maternal infections during pregnancy and congenital defects in their offspring: a population-based case-control study in Bogota and Cali, Colombia 2001-2018. 62
34749588 2022
Clonal groups of extended-spectrum β-lactamase and biofilm producing uropathogenic Escherichia coli in Iran. 62
34904540 2022
Ceftazidime encephalopathy developed without the elevation of cerebrospinal fluid concentration of ceftazidime: A case report of two cases. 62
36028210 2022
Evaluating the Need for Prolonged Telemetry Monitoring in Patients With Isolated Sternal Fractures. 62
36030608 2022
Nurse-in-the-loop smart home detection of health events associated with diagnosed chronic conditions: A case-event series. 62
35642184 2022
The efficacy of the American College of Surgeons Surgical Risk Calculator in the prediction of postoperative complications in oncogeriatric patients after curative surgery for abdominal tumors. 62
35924711 2022
Implementation of a standardized voiding protocol after minimally invasive surgery: A quality improvement initiative. 62
35490400 2022
Predicting mortality in moderate-severe TBI patients without early withdrawal of life-sustaining treatments including ICU complications: The MYSTIC-score. 62
36166912 2022
Preventing pediatric catheter-associated urinary tract infections utilizing urinary catheter Kamishibai cards (K-cards). 62
36463976 2022
Novel agents in development for multidrug-resistant Gram-negative infections: potential new options facing multiple challenges. 62
36206150 2022
Infectious complications in adult patients with idiopathic minimal change nephrotic syndrome undergoing immunosuppressive therapy. 62
36209374 2022
Surgical treatment of proximal femoral fractures in centenarians: prevalence and outcomes based on a German multicenter study. 62
36469083 2022
Multinational Prospective Cohort Study of Mortality Risk Factors in 198 ICUs of 12 Latin American Countries over 24 Years: The Effects of Healthcare-Associated Infections. 62
36197596 2022
Transvaginal approach for rectovaginal fistula: experience from a single institution. 62
36161396 2022
A Deception Study to Avoid Recall Bias Confirms Similar Scores for 3 Validated Questionnaires in the Office or Over the Phone in Women With or Without Urinary Incontinence. 62
36036901 2022
Impact of bacterial infections and spontaneous bacterial peritonitis prophylaxis on phage-bacterial dynamics in cirrhosis. 62
35561076 2022
Feasibility of immediate removal of urinary catheter after laparoscopic gynecological surgery for benign diseases: A meta-analysis of randomized controlled trials. 62
35616374 2022
Zinner syndrome in children: clinical presentation, imaging findings, diagnosis, and outcome. 62
35332378 2022
Exposure to industrial hog and poultry operations and urinary tract infections in North Carolina, USA. 62
36108846 2022
Simple determination of urine cefazolin concentration in pediatric patients with urinary tract infections using high-performance liquid chromatography. 62
36049091 2022
Urinary tract infections in patients with multiple sclerosis and different methods of bladder evacuation. 62
36216764 2022
Bacterial filamentation during urinary tract infections. 62
36454736 2022
Reducing antibiotic use in uncomplicated urinary tract infections in adult women: a systematic review and individual participant data meta-analysis. 62
35788049 2022
Usefulness of flow cytometry in the diagnosis of urinary tract infections caused by fastidious microorganisms: a case report of acute cystitis caused by Actinotignum schaalii. 62
35787349 2022

Variations for Urinary Tract Infection

ClinVar genetic disease variations for Urinary Tract Infection:

# Gene Name Type Significance ClinVarId dbSNP ID Position
1 EBF3 NM_001375380.1(EBF3):c.280_283del (p.Glu94fs) DEL Pathogenic
375502 rs1057519521 GRCh37: 10:131761639-131761642
GRCh38: 10:129963375-129963378

Expression for Urinary Tract Infection

Search GEO for disease gene expression data for Urinary Tract Infection.

Pathways for Urinary Tract Infection

Pathways related to Urinary Tract Infection according to GeneCards Suite gene sharing:

(show all 21)
# Super pathways Score Top Affiliating Genes
1 11.9 ALB IL6 INS VIM
2 11.79 VIM TNF IL6 CXCL8
3 11.74 VIM TNF CXCL8
Show member pathways
11.65 IL6 CXCL8 CRP
5 11.63 TNF IL6 CXCL8
6 11.6 VIM IL6 CXCL8 CCR6
7 11.59 TNF IL6 CRP
8 11.59 VIM TNF LCN2 IL6 CXCL8
Show member pathways
11.53 TNF IL6 CXCL8
10 11.52 TNF IL6 CXCL8
11 11.47 INS IL6 CXCL8
12 11.41 TNF IL6 CXCL8
13 11.36 TNF IL6 CXCL8
14 11.35 TNF LCN2 IL6 CXCL8
15 11.33 TNF INS IL6
16 11.11 TNF IL6 CXCL8
17 11.03 TNF IL6 CXCL8
18 10.98 TNF IL6 CXCL8
19 10.59 IL6 CXCL8
20 10.2 TNF IL6 CXCL8 CRP
Show member pathways
9.83 TNF IL6 CXCL8

GO Terms for Urinary Tract Infection

Biological processes related to Urinary Tract Infection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 9.43 INS IL6 CRP
2 negative regulation of lipid storage GO:0010888 9.1 TNF IL6 CRP

Molecular functions related to Urinary Tract Infection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enterobactin binding GO:1903981 8.92 LCN2 ALB

Sources for Urinary Tract Infection

8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
27 GO
28 GTR
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
36 LifeMap
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
70 Tocris
72 UMLS via Orphanet
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