MCID: URN022
MIFTS: 29

Urinary Tract Infections, Recurrent

Categories: Nephrological diseases

Aliases & Classifications for Urinary Tract Infections, Recurrent

MalaCards integrated aliases for Urinary Tract Infections, Recurrent:

Name: Urinary Tract Infections, Recurrent 57
Urinary Tract Infections, Recurrent, Susceptibility to 57 29
Recurrent Urinary Tract Infections 29
Urinary Tract Infection Recurrent 55
Recurrent Urinary Tract Infection 73

Classifications:



External Ids:

OMIM 57 603806
UMLS 73 C0262655

Summaries for Urinary Tract Infections, Recurrent

MalaCards based summary : Urinary Tract Infections, Recurrent, also known as urinary tract infections, recurrent, susceptibility to, is related to acute cystitis. An important gene associated with Urinary Tract Infections, Recurrent is CXCR1 (C-X-C Motif Chemokine Receptor 1). The drugs Levofloxacin and Ofloxacin have been mentioned in the context of this disorder. Affiliated tissues include prostate, kidney and spinal cord.

Description from OMIM: 603806

Related Diseases for Urinary Tract Infections, Recurrent

Diseases related to Urinary Tract Infections, Recurrent via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 acute cystitis 11.3

Symptoms & Phenotypes for Urinary Tract Infections, Recurrent

Clinical features from OMIM:

603806

Drugs & Therapeutics for Urinary Tract Infections, Recurrent

Drugs for Urinary Tract Infections, Recurrent (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 544)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 100986-85-4 149096
2
Ofloxacin Approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 82419-36-1 4583
3
Nitrofurantoin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 67-20-9 5353830
4
Trimethoprim Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 738-70-5 5578
5
Piperacillin Approved Phase 4,Phase 3,Phase 2,Not Applicable 66258-76-2 43672
6
Sulbactam Approved Phase 4,Phase 2 68373-14-8
7
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 55-56-1 9552079 2713
8
Iodine Approved, Investigational Phase 4,Phase 2,Not Applicable 7553-56-2 807
9
Povidone Approved Phase 4,Phase 2,Not Applicable 9003-39-8
10
Povidone-iodine Approved Phase 4,Phase 2,Not Applicable 25655-41-8
11
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
12
Finasteride Approved Phase 4 98319-26-7 57363
13
Tamsulosin Approved, Investigational Phase 4,Phase 3,Early Phase 1 106133-20-4 129211
14
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 26787-78-0 33613
15
Azithromycin Approved Phase 4,Not Applicable 83905-01-5 55185 447043
16
Cefotaxime Approved Phase 4,Not Applicable 63527-52-6 456256 5742673
17
Cefoxitin Approved Phase 4,Not Applicable 35607-66-0 441199
18
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 85721-33-1 2764
19
Imipenem Approved Phase 4,Phase 3,Phase 2 74431-23-5, 64221-86-9 104838
20
Vancomycin Approved Phase 4,Phase 3,Not Applicable 1404-90-6 441141 14969
21
Metronidazole Approved Phase 4,Phase 3,Not Applicable,Early Phase 1 443-48-1 4173
22
Tranexamic Acid Approved Phase 4,Phase 3,Not Applicable 1197-18-8 5526
23
Fosfomycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 23155-02-4 446987
24
Sulfamethoxazole Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 723-46-6 5329
25
Cephalexin Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 15686-71-2 27447
26
Cefuroxime Approved Phase 4,Not Applicable,Early Phase 1 55268-75-2 5361202 5479529
27
Cefazolin Approved Phase 4,Phase 1,Not Applicable 25953-19-9 656510 33255
28
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 51-43-4 5816
29
Racepinephrine Approved Phase 4,Phase 3,Not Applicable 329-65-7 838
30
Menthol Approved Phase 4,Phase 3,Not Applicable 2216-51-5 16666
31
Methenamine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 100-97-0 4101
32
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Not Applicable 83-43-2 6741
33
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 128794-94-5 5281078
34
Mycophenolic acid Approved Phase 4,Phase 1,Phase 2,Not Applicable 24280-93-1 446541
35
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Not Applicable 50-24-8 5755
36
Tacrolimus Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 104987-11-3 445643 439492
37
Tobramycin Approved, Investigational Phase 4 32986-56-4 5496 36294
38
Ampicillin Approved, Vet_approved Phase 4,Not Applicable 69-53-4 6249
39
Ceftriaxone Approved Phase 4,Phase 3,Phase 2 73384-59-5 5479530 5361919
40
Cefixime Approved, Investigational Phase 4,Phase 3,Phase 2 79350-37-1 54362 5362065
41
Ibuprofen Approved Phase 4 15687-27-1 3672
42
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-28-2 5757
43 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 979-32-8
44
Polyestradiol phosphate Approved Phase 4,Phase 3,Phase 2 28014-46-2
45
Silver sulfadiazine Approved, Vet_approved Phase 4 22199-08-2 441244
46
Sulfadiazine Approved, Investigational, Vet_approved Phase 4 68-35-9 5215
47
Etanercept Approved, Investigational Phase 4 185243-69-0
48
Colistin Approved Phase 4,Phase 3,Not Applicable 1264-72-8, 1066-17-7 5311054
49
Neomycin Approved, Vet_approved Phase 4,Early Phase 1 1404-04-2 8378
50
Norfloxacin Approved Phase 4,Phase 2 70458-96-7 4539

Interventional clinical trials:

(show top 50) (show all 935)
# Name Status NCT ID Phase Drugs
1 Low Dose Estriol With Lactobacilli Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women Unknown status NCT00900653 Phase 4 Gynoflor E (low dose estriol with lactobacillus)
2 Cranberry for the Prevention of Urinary Tract Infections Unknown status NCT02454309 Phase 4
3 The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Urinary Tract Infection in Females Unknown status NCT02094703 Phase 4 Levofloxacin;Solifenacin succinate;Placebo (for Solifenacin succinate)
4 Effects of Antibiotic Prophylaxis on Recurrent UTI in Children Unknown status NCT02357758 Phase 4 Antibiotic Prophylaxis
5 Gentamicin Bladder Instillation Trial Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
6 Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
7 Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a Previous Urinary Tract Infection Unknown status NCT00156546 Phase 4 antibiotic to reduce the recurrence of infection
8 BIP Foley in Prevention of CAUTI at Rehab Station Unknown status NCT02808000 Phase 4
9 Piperacillin Sodium and Sulbactam Sodium for Injection(2:1) for Treatment of Respiratory and Urinary System Infection Unknown status NCT01760109 Phase 4 Piperacillin Sodium and Sulbactam Sodium
10 Effect of Chlorhexidine on Bacteriuria Unknown status NCT02032394 Phase 4 Povidone-iodine;Chlorhexidine;Normal saline
11 Bladder Lavage as Decontamination Method for Asymptomatic Bacteriuria With Uropathogens in Catheterized Patients Unknown status NCT01772875 Phase 4
12 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
13 A Prospective Study Comparing the Success Rate of Injection of (DefluxR) Versus (VantrisR) for VUR in Children Unknown status NCT02271035 Phase 4 Deflux;Vantris
14 Advanced Benefits of Alpha-blocker Monotherapy on Lower Urinary Tracts Symptoms(LUTS) Patients Unknown status NCT01736033 Phase 4 Tamsulosin;Finasteride;Placebo
15 Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis Unknown status NCT01820026 Phase 4 Imipenem;Vancomycin;azithromycin;Cefotaxime;Amoxicillin
16 Efficiency of Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures Unknown status NCT01196572 Phase 4
17 Effect of Enteral Genistein Supplementation in Sepsis Unknown status NCT02796794 Phase 4
18 Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury Unknown status NCT00201968 Phase 4
19 Ciprofloxacin for Prevention of BK Infection Unknown status NCT01789203 Phase 4 Ciprofloxacin;placebo
20 Diverticulitis: Antibiotics or Close Observation? Unknown status NCT01111253 Phase 4 Amoxicillin-clavulanate
21 Effect of Omega-3 Fatty Acids on the Perioperative Immune Response and Erythrocyte Function Unknown status NCT02231203 Phase 4 Omegaven;Placebo
22 Tranexamic Acid in Knee Joint Surgery Unknown status NCT02278263 Phase 4 Tranexamic Acid;Normal saline (0.9% NaCl)
23 The Effect of Chest Tubes Using Active Clearance Technology® on the Incidence of Postoperative Atrial Fibrillation Unknown status NCT02808897 Phase 4
24 Perioperative Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients Completed NCT03235947 Phase 4 Fosfomycin disodium;Trimethoprim / Sulfamethoxazole;Intravenous placebo
25 Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI) Completed NCT01450800 Phase 4 Nitrofurantoin;Placebo
26 Comparative Study of Intermittent Catheters and Occurrence of Urinary Tract Infections Completed NCT00318591 Phase 4
27 Efficacy and Safety of Nitrofurantoin in the Treatment of Uncomplicated Urinary Tract Infections in Adults Completed NCT01092351 Phase 4 Nitrofurantoin
28 Febrile Urinary Tract Infection Randomized Short Treatment Trial Completed NCT00809913 Phase 4 short treatment (ciprofloxacin)
29 Safety and Efficacy of a Weekly Oral Cyclic Antibiotic Programme in the Prevention of Urinary Tract Infection on Neurological Bladder Completed NCT01388413 Phase 4 Weekly Oral Cyclic Antibiotic programme
30 Study To Evaluate The Efficacy And Safety Of Ciprofloxacin Extended-Release (Cipro® XR) 1000 mg Tablets Given Once Daily For 7 To 14 Days In The Treatment Of Patients 18 Years Or Older With Complicated Urinary Tract Infections Caused By Pseudomonas Aerugi Completed NCT00481689 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
31 Trial to Evaluate the Efficacy and Safety of Cipro® XR in Treating Female Patients With Lower Urinary Tract Infections Completed NCT00669994 Phase 4 Ciprofloxacin
32 Efficacy of Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation Completed NCT01820897 Phase 4 Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
33 Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - ICUTI Completed NCT01488955 Phase 4 Ibuprofen;Fosfomycin-Trometamol
34 Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women Completed NCT01958073 Phase 4 Conjugated Estrogen Vaginal Cream;Estradiol Ring;Placebo
35 Cipro® XR in Therapeutic Response and Activity (eXtRa) - Assessing Symptom Relief in Urinary Tract Infections Completed NCT00676533 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
36 A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infections Completed NCT00965848 Phase 4 Doripenem
37 Antibiotic Prophylaxis for Clean Intermittent Catheterisation Completed NCT02145338 Phase 4 Nitrofurantoin or Trimethoprim or Cefalexin
38 Management of Urinary Tract Infections in Primary Care Facilities. Completed NCT01132131 Phase 4
39 Does Treatment With Macrobid Reduce Urinary Tract Infections in Patients Receiving a Sub-Urethral Sling for Incontinence Completed NCT00734968 Phase 4 Nitrofurantoin
40 A Phase IV Study of Cipro XR in Uncomplicated UTI Completed NCT00663806 Phase 4
41 Prophylactic Antibiotics on Urethral Catheter Withdrawal Completed NCT00126698 Phase 4 trimethoprim-sulfamethoxazole;ciprofloxacin
42 Pharmacokinetics of Ciprofloxacin in Pediatric Patients Completed NCT02598362 Phase 4 ciprofloxacin
43 Efficacy Study of Prophylaxis With Fosfomycin Versus Ciprofloxacin Prior Prostate Biopsy Completed NCT01803191 Phase 4 Fosfomycin 3 g;Ciprofloxacin 500 mg
44 Treatment's Duration of Acute Uncomplicated Pyelonephritis Completed NCT00873626 Phase 4 levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
45 Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery Completed NCT02727322 Phase 4 Nitrofurantoin;Placebo
46 Antibiotics and Gut Microbiota Among Newborn Infants Completed NCT02072798 Phase 4 Cefuroxime
47 PROUD Study: A Prospective Study on the Usage Patterns of Doripenem in the Asia Pacific Region Completed NCT00986102 Phase 4 doripenem
48 A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral Reflux Completed NCT00382343 Phase 4 Sulfamethoxazole/trimethoprim
49 Comparison of Antimicrobial Coated Ureteral Stents With Non-coated Stents Completed NCT02266368 Phase 4
50 Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders Completed NCT00132418 Phase 4 Enbrel;Placebo

Search NIH Clinical Center for Urinary Tract Infections, Recurrent

Genetic Tests for Urinary Tract Infections, Recurrent

Genetic tests related to Urinary Tract Infections, Recurrent:

# Genetic test Affiliating Genes
1 Urinary Tract Infections, Recurrent, Susceptibility to 29
2 Recurrent Urinary Tract Infections 29

Anatomical Context for Urinary Tract Infections, Recurrent

MalaCards organs/tissues related to Urinary Tract Infections, Recurrent:

41
Prostate, Kidney, Spinal Cord, Colon, Testes, Liver, Heart

Publications for Urinary Tract Infections, Recurrent

Articles related to Urinary Tract Infections, Recurrent:

(show all 45)
# Title Authors Year
1
Stigma and self-management: an Interpretative Phenomenological Analysis of the impact of chronic recurrent urinary tract infections after spinal cord injury. ( 29449969 )
2018
2
An exceptional source of recurrent urinary tract infections in women: Primary retroperitoneal serous cystadenoma. ( 29458894 )
2018
3
Incidental Finding of Urethral Diverticulum in a Woman with History of Recurrent Urinary Tract Infections. ( 29692697 )
2018
4
Recurrent Urinary Tract Infections in a Female Child With Polydactyly and a Pelvic Mass: Consider the McKusick-Kaufman Syndrome. ( 28153592 )
2017
5
Urinary NGAL deficiency in recurrent urinary tract infections. ( 28210838 )
2017
6
A Case of Distal Vaginal Agenesis Presenting with Recurrent Urinary Tract Infection and Pyuria in A Prepubertal Girl. ( 27555476 )
2016
7
Recurrent Urinary Tract Infections in Children With Bladder and Bowel Dysfunction. ( 26647376 )
2016
8
Efficacy of Cranberry in Preventing Recurrent Urinary Tract Infections: Have We Learned Anything New? Commentary on: Effect of Cranberry Capsules on Bacteriuria Plus Pyuria Among Older Women in Nursing Homes: A Randomized Clinical Trial. ( 28024965 )
2016
9
Mannose-binding lectin genetic analysis: possible protective role of the HYPA haplotype in the development of recurrent urinary tract infections in men. ( 24321858 )
2014
10
Ultrasound distinction between simple recurrent urinary tract infections and a specific bladder wall inflammatory entity called cystitis cystica. ( 24851610 )
2014
11
The predictive value of urinary UPIb mRNA levels in VUR and recurrent urinary tract infections. ( 24559587 )
2014
12
Does hydrochlorothiazide prevent recurrent urinary tract infection in children with idiopathic hypercalciuria? ( 23131530 )
2013
13
Positive feedback loop for cystitis cystica: the effect of recurrent urinary tract infection on the number of bladder wall mucosa nodules. ( 24696993 )
2013
14
Ultrasound bladder wall thickness measurement in diagnosis of recurrent urinary tract infections and cystitis cystica in prepubertal girls. ( 23725853 )
2013
15
Diagnosis and follow-up of chronic bacterial prostatitis with recurrent urinary tract infection detected by 67Ga scintigraphy and SPECT/CT. ( 24089068 )
2013
16
Urinary Tract Abnormalities In Patients With Recurrent Urinary Tract Infections (UTI) After Hypospadias Repair. ( 24053220 )
2013
17
The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: to treat or not to treat? ( 22677710 )
2012
18
Prophylaxis of recurrent urinary tract infection after renal transplantation by cranberry juice and L-methionine. ( 23195017 )
2012
19
Small bowel adenocarcinoma presenting with recurrent urinary tract infection. ( 22771413 )
2012
20
Recurrent Urinary Tract Infections due to Asymptomatic Colonic Diverticulitis. ( 22454651 )
2012
21
Asymptomatic proteinuria in a child with recurrent urinary tract infections--questions. ( 21993968 )
2012
22
Bladder calculus presenting as recurrent urinary tract infections: a late complication of cervical cerclage placement: a case report. ( 21542538 )
2011
23
B cell infiltration and lymphonodular hyperplasia in bladder submucosa of patients with persistent bacteriuria and recurrent urinary tract infections. ( 22019034 )
2011
24
Complete duplication of collecting system in a horseshoe kidney presenting with recurrent urinary tract infections: report of an exceedingly rare congenital anomaly and review of literature. ( 22224073 )
2011
25
Pheochromocytoma presenting as recurrent urinary tract infections : a case report. ( 21226896 )
2011
26
Recurrent urinary tract infections in an infant with antenatal Bartter syndrome. ( 20127218 )
2011
27
Risk factors for recurrent urinary tract infection in infants with vesicoureteral reflux during prophylactic treatment: effect of delayed contrast passage on voiding cystourethrogram. ( 21316084 )
2011
28
Polymorphisms in the surfactant protein a gene are associated with the susceptibility to recurrent urinary tract infection in chinese women. ( 20448439 )
2010
29
Risk factors for recurrent urinary tract infections in a cohort of patients with primary vesicoureteral reflux. ( 20135833 )
2010
30
Cystitis cystica and recurrent urinary tract infections in children. ( 20977079 )
2010
31
Predicting early recurrent urinary tract infection in pretoilet trained children with vesicoureteral reflux. ( 19692080 )
2009
32
Antibiotic prophylaxis for the prevention of recurrent urinary tract infection in children with low grade vesicoureteral reflux: results from a prospective randomized study. ( 18082208 )
2008
33
Re: Antibiotic prophylaxis for the prevention of recurrent urinary tract infection in children with low grade vesicoureteral reflux: results from a prospective randomized study: G. Roussey-Kesler, V. Gadjos, N. Idres, B. Horen, L. Ichay, M. D. Leclair, F. Raymond, A. Grellier, I. Hazart, L. De parscau, R. Salomon, G. Champion, V. Leroy, V. Guigonis, D. Siret, J. B. Palcoux,S. Taque, A. Lemoigne, J. M. Nguyen and C. Guyot. J Urol 2008; 179: 674-679. ( 18804797 )
2008
34
Cystoscopy in women with recurrent urinary tract infection. ( 16734849 )
2006
35
Polymorphisms of the angiotensin converting enzyme and angiotensin II type 1 receptor genes and renal scarring in non-uropathic children with recurrent urinary tract infection. ( 16109085 )
2005
36
Expression of interleukin-8 receptors (CXCR1 and CXCR2) in premenopausal women with recurrent urinary tract infections. ( 16339057 )
2005
37
[Urinary excretion of Tamm-Horsfall protein, albumin and beta-2 microglobulin in children with recurrent urinary tract infection]. ( 11579828 )
2001
38
In vitro contractile responses of detrusor to carbachol and neurokinin A, in children with recurrent urinary tract infection or day wetting. ( 10671891 )
2000
39
Management of recurrent urinary tract infection and vesicoureteral reflux in children. ( 10650511 )
2000
40
Recurrent urinary tract infections and genitourinary tract abnormalities in the Imerslund-GrAosbeck syndrome. ( 10845232 )
2000
41
The office management of recurrent urinary tract infection and vesicoureteral reflux in children. ( 10026778 )
1998
42
[Recurrent urinary tract infections. Biological suppositions and clinical treatment with thymopentin]. ( 9557507 )
1997
43
Pleomorphic rhabdomyosarcoma of the urinary bladder in association with recurrent urinary-tract infection. ( 2703059 )
1989
44
Congenital anterior urethral diverticulum and recurrent urinary tract infection. ( 2514575 )
1989
45
How should girls with recurrent urinary tract infection and persistent vaginal discharge be managed? ( 2642097 )
1989

Variations for Urinary Tract Infections, Recurrent

Expression for Urinary Tract Infections, Recurrent

Search GEO for disease gene expression data for Urinary Tract Infections, Recurrent.

Pathways for Urinary Tract Infections, Recurrent

GO Terms for Urinary Tract Infections, Recurrent

Sources for Urinary Tract Infections, Recurrent

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