MCID: URN011
MIFTS: 25

Urinary Tract Papillary Transitional Cell Benign Neoplasm

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Urinary Tract Papillary Transitional Cell Benign Neoplasm

MalaCards integrated aliases for Urinary Tract Papillary Transitional Cell Benign Neoplasm:

Name: Urinary Tract Papillary Transitional Cell Benign Neoplasm 12 15
Papillary Transitional Cell Neoplasm of the Urinary Tract 12
Inverted Papilloma of Urinary Tract 12
Urinary Tract Inverted Papilloma 12
Inverted Urothelial Papilloma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5433
NCIt 50 C27883 C6192

Summaries for Urinary Tract Papillary Transitional Cell Benign Neoplasm

MalaCards based summary : Urinary Tract Papillary Transitional Cell Benign Neoplasm, also known as papillary transitional cell neoplasm of the urinary tract, is related to inverted papilloma and papilloma. An important gene associated with Urinary Tract Papillary Transitional Cell Benign Neoplasm is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways are Bladder cancer and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include lung, ovary and cervix, and related phenotype is hematopoietic system.

Related Diseases for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Diseases related to Urinary Tract Papillary Transitional Cell Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 inverted papilloma 30.3 KRT20 TP53
2 papilloma 30.1 FGFR3 KRT20 TP53
3 papillary transitional carcinoma 10.2 KRT20 PTCRA
4 vulval paget's disease 10.2 KRT20 PTCRA
5 actinic cheilitis 10.2 FGFR3 TP53
6 vulva adenocarcinoma 10.2 KRT20 PTCRA
7 colloid adenoma 10.1 KRT20 TP53
8 fibroepithelial basal cell carcinoma 10.1 KRT20 TP53
9 papillary serous adenocarcinoma 10.1 KRT20 TP53
10 glycogen-rich clear cell breast carcinoma 10.1 KRT20 TP53
11 cervix carcinoma 10.1 FGFR3 TP53
12 biliary papillomatosis 10.1 KRT20 TP53
13 endocervical adenocarcinoma 10.1 KRT20 TP53
14 cervical adenocarcinoma 10.1 KRT20 TP53
15 eccrine sweat gland neoplasm 10.1 KRT20 TP53
16 giant cell glioblastoma 10.1 FGFR3 TP53
17 appendix cancer 10.1 KRT20 TP53
18 cystic teratoma 10.1 KRT20 TP53
19 pseudomyxoma peritonei 10.1 KRT20 TP53
20 ampulla of vater cancer 10.1 KRT20 TP53
21 pancreatic ductal carcinoma 10.1 KRT20 TP53
22 actinic keratosis 10.1 KRT20 TP53
23 factor v deficiency 10.1 LMAN1 PTCRA
24 small cell carcinoma 10.1 KRT20 TP53
25 sweat gland cancer 10.1 KRT20 TP53
26 merkel cell carcinoma 10.1 KRT20 TP53
27 scrotal carcinoma 10.0 ANO2 TP53
28 colorectal adenocarcinoma 10.0 KRT20 TP53
29 non-invasive bladder papillary urothelial neoplasm 10.0 FGFR3 PTCRA TP53
30 rectal neoplasm 10.0 KRT20 TP53
31 transitional cell carcinoma 10.0 FGFR3 KRT20 TP53
32 bladder urothelial carcinoma 10.0 FGFR3 KRT20 TP53
33 ureter, cancer of 10.0 PTCRA TERT
34 intrahepatic cholangiocarcinoma 10.0 KRT20 TP53
35 cystitis cystica 10.0 KRT20 TERT
36 soft tissue sarcoma 10.0 TERT TP53
37 testicular germ cell tumor 10.0 FGFR3 TP53
38 dyskeratosis congenita autosomal recessive 10.0 TERT TP53
39 supratentorial cancer 9.9 TERT TP53
40 cerebrum cancer 9.9 TERT TP53
41 anaplastic thyroid cancer 9.9 TERT TP53
42 laryngeal squamous cell carcinoma 9.9 TERT TP53
43 gliosarcoma 9.9 FGFR3 TP53
44 respiratory system cancer 9.8 TERT TP53
45 cholangiocarcinoma 9.8 KRT20 TERT TP53
46 large intestine cancer 9.8 KRT20 TERT TP53
47 cervical cancer 9.7 FGFR3 TERT TP53
48 lung cancer susceptibility 3 9.7 FGFR3 KRT20 TERT TP53
49 bladder cancer 9.7 FGFR3 KRT20 TERT TP53
50 bladder disease 9.6 FGFR3 KRT20 PTCRA TERT TP53

Graphical network of the top 20 diseases related to Urinary Tract Papillary Transitional Cell Benign Neoplasm:



Diseases related to Urinary Tract Papillary Transitional Cell Benign Neoplasm

Symptoms & Phenotypes for Urinary Tract Papillary Transitional Cell Benign Neoplasm

MGI Mouse Phenotypes related to Urinary Tract Papillary Transitional Cell Benign Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.1 FGFR3 LMAN1 PTCRA PTGES2 TERT TP53

Drugs & Therapeutics for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Genetic Tests for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Anatomical Context for Urinary Tract Papillary Transitional Cell Benign Neoplasm

MalaCards organs/tissues related to Urinary Tract Papillary Transitional Cell Benign Neoplasm:

41
Lung, Ovary, Cervix, Thyroid, Appendix

Publications for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Articles related to Urinary Tract Papillary Transitional Cell Benign Neoplasm:

# Title Authors Year
1
Inverted papilloma of urinary tract. ( 7404908 )
1980

Variations for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Cosmic variations for Urinary Tract Papillary Transitional Cell Benign Neoplasm:

9 (show all 11)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM496 HRAS urinary tract,NS,papilloma,inverted c.181C>A p.Q61K 11:533875-533875 11
2 COSM715 FGFR3 urinary tract,NS,papilloma,inverted c.746C>G p.S249C 4:1801841-1801841 11
3 COSM714 FGFR3 urinary tract,NS,papilloma,inverted c.742C>T p.R248C 4:1801837-1801837 11
4 COSM29438 FGFR3 urinary tract,NS,papilloma,inverted c.1921G>A p.D641N 4:1806135-1806135 11
5 COSM29432 FGFR3 urinary tract,NS,papilloma,inverted c.775C>T p.L259L 4:1801870-1801870 11
6 COSM29431 FGFR3 urinary tract,NS,papilloma,inverted c.745T>A p.S249T 4:1801840-1801840 11
7 COSM29434 FGFR3 urinary tract,NS,papilloma,inverted c.796G>A p.V266M 4:1801891-1801891 11
8 COSM29437 FGFR3 urinary tract,NS,papilloma,inverted c.1881G>T p.E627D 4:1806095-1806095 11
9 COSM29439 FGFR3 urinary tract,NS,papilloma,inverted c.1927C>G p.H643D 4:1806141-1806141 11
10 COSM29436 FGFR3 urinary tract,NS,papilloma,inverted c.1236C>T p.H412H 4:1804490-1804490 11
11 COSM29440 FGFR3 urinary tract,NS,papilloma,inverted c.1957A>C p.N653H 4:1806171-1806171 11

Expression for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Search GEO for disease gene expression data for Urinary Tract Papillary Transitional Cell Benign Neoplasm.

Pathways for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Pathways related to Urinary Tract Papillary Transitional Cell Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.02 FGFR3 TP53
2
Show member pathways
11.01 FGFR3 TERT TP53
3 10.77 FGFR3 TP53

GO Terms for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Biological processes related to Urinary Tract Papillary Transitional Cell Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 8.96 TERT TP53
2 replicative senescence GO:0090399 8.62 TERT TP53

Sources for Urinary Tract Papillary Transitional Cell Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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