MCID: URN011
MIFTS: 27

Urinary Tract Papillary Transitional Cell Benign Neoplasm

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Urinary Tract Papillary Transitional Cell Benign Neoplasm

MalaCards integrated aliases for Urinary Tract Papillary Transitional Cell Benign Neoplasm:

Name: Urinary Tract Papillary Transitional Cell Benign Neoplasm 12 15
Papillary Transitional Cell Neoplasm of the Urinary Tract 12
Inverted Papilloma of Urinary Tract 12
Urinary Tract Inverted Papilloma 12
Inverted Urothelial Papilloma 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5433
NCIt 51 C27883 C6192

Summaries for Urinary Tract Papillary Transitional Cell Benign Neoplasm

MalaCards based summary : Urinary Tract Papillary Transitional Cell Benign Neoplasm, also known as papillary transitional cell neoplasm of the urinary tract, is related to inverted papilloma and papilloma. An important gene associated with Urinary Tract Papillary Transitional Cell Benign Neoplasm is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways are Pathways in cancer and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include skin, brain and colon, and related phenotypes are hematopoietic system and neoplasm

Related Diseases for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Diseases related to Urinary Tract Papillary Transitional Cell Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 inverted papilloma 30.4 KRT20 TP53
2 papilloma 30.2 FGFR3 KRT20 TP53
3 colloid adenoma 10.2 KRT20 TP53
4 fibroepithelial basal cell carcinoma 10.2 KRT20 TP53
5 papillary serous adenocarcinoma 10.2 KRT20 TP53
6 glycogen-rich clear cell breast carcinoma 10.2 KRT20 TP53
7 biliary papillomatosis 10.2 KRT20 TP53
8 endocervical adenocarcinoma 10.2 KRT20 TP53
9 cervical adenocarcinoma 10.2 KRT20 TP53
10 eccrine sweat gland neoplasm 10.2 KRT20 TP53
11 appendix cancer 10.2 KRT20 TP53
12 cystic teratoma 10.2 KRT20 TP53
13 pseudomyxoma peritonei 10.2 KRT20 TP53
14 cervix carcinoma 10.2 FGFR3 TP53
15 ampulla of vater cancer 10.2 KRT20 TP53
16 pancreatic ductal carcinoma 10.2 KRT20 TP53
17 giant cell glioblastoma 10.2 FGFR3 TP53
18 soft tissue sarcoma 10.2 TERT TP53
19 cystitis cystica 10.2 KRT20 TERT
20 jejunal adenocarcinoma 10.2 KRT20 MSH6
21 dyskeratosis congenita autosomal recessive 10.2 TERT TP53
22 actinic keratosis 10.2 KRT20 TP53
23 cecum adenocarcinoma 10.1 KRT20 MSH6
24 small cell carcinoma 10.1 KRT20 TP53
25 sweat gland cancer 10.1 KRT20 TP53
26 skin benign neoplasm 10.1 KRT20 MSH6
27 squamous cell papilloma 10.1
28 supratentorial cancer 10.1 TERT TP53
29 small intestine cancer 10.1 KRT20 MSH6
30 cerebrum cancer 10.1 TERT TP53
31 merkel cell carcinoma 10.1 KRT20 TP53
32 transitional cell carcinoma 10.0 FGFR3 KRT20 TP53
33 bladder urothelial carcinoma 10.0 FGFR3 KRT20 TP53
34 uterine anomalies 10.0 MSH6 TP53
35 laryngeal squamous cell carcinoma 10.0 TERT TP53
36 colonic disease 10.0 MSH6 TP53
37 cholangiocarcinoma 10.0 KRT20 TERT TP53
38 colorectal adenocarcinoma 9.9 KRT20 MSH6 TP53
39 hereditary breast ovarian cancer syndrome 9.9 MSH6 TP53
40 female reproductive system disease 9.9 MSH6 TP53
41 brain cancer 9.8 MSH6 TERT TP53
42 non-invasive bladder papillary urothelial neoplasm 9.8 FGFR3 SIGLEC12 TP53
43 bladder disease 9.8 FGFR3 KRT20 TERT TP53
44 lung cancer susceptibility 3 9.8 FGFR3 KRT20 TERT TP53
45 bladder cancer 9.8 FGFR3 KRT20 TERT TP53
46 large intestine cancer 9.7 KRT20 MSH6 TERT TP53
47 cervical cancer 9.6 FGFR3 TERT TP53
48 bladder papillary transitional cell neoplasm 9.1 FGFR3 KRT20 LMAN1 PTGES2 TERT TP53

Graphical network of the top 20 diseases related to Urinary Tract Papillary Transitional Cell Benign Neoplasm:



Diseases related to Urinary Tract Papillary Transitional Cell Benign Neoplasm

Symptoms & Phenotypes for Urinary Tract Papillary Transitional Cell Benign Neoplasm

MGI Mouse Phenotypes related to Urinary Tract Papillary Transitional Cell Benign Neoplasm:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.43 FGFR3 LMAN1 MSH6 PTGES2 TERT TP53
2 neoplasm MP:0002006 8.92 FGFR3 MSH6 TERT TP53

Drugs & Therapeutics for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Genetic Tests for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Anatomical Context for Urinary Tract Papillary Transitional Cell Benign Neoplasm

MalaCards organs/tissues related to Urinary Tract Papillary Transitional Cell Benign Neoplasm:

42
Skin, Brain, Colon, Cervix, Small Intestine, Appendix

Publications for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Articles related to Urinary Tract Papillary Transitional Cell Benign Neoplasm:

# Title Authors Year
1
Inverted papilloma of urinary tract. ( 7404908 )
1980

Variations for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Cosmic variations for Urinary Tract Papillary Transitional Cell Benign Neoplasm:

9 (show all 11)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM496 HRAS urinary tract,NS,papilloma,inverted c.181C>A p.Q61K 11:533875-533875 0
2 COSM29440 FGFR3 urinary tract,NS,papilloma,inverted c.1957A>C p.N653H 4:1806171-1806171 0
3 COSM715 FGFR3 urinary tract,NS,papilloma,inverted c.746C>G p.S249C 4:1801841-1801841 0
4 COSM29438 FGFR3 urinary tract,NS,papilloma,inverted c.1921G>A p.D641N 4:1806135-1806135 0
5 COSM714 FGFR3 urinary tract,NS,papilloma,inverted c.742C>T p.R248C 4:1801837-1801837 0
6 COSM29432 FGFR3 urinary tract,NS,papilloma,inverted c.775C>T p.L259L 4:1801870-1801870 0
7 COSM29431 FGFR3 urinary tract,NS,papilloma,inverted c.745T>A p.S249T 4:1801840-1801840 0
8 COSM29434 FGFR3 urinary tract,NS,papilloma,inverted c.796G>A p.V266M 4:1801891-1801891 0
9 COSM29437 FGFR3 urinary tract,NS,papilloma,inverted c.1881G>T p.E627D 4:1806095-1806095 0
10 COSM29439 FGFR3 urinary tract,NS,papilloma,inverted c.1927C>G p.H643D 4:1806141-1806141 0
11 COSM29436 FGFR3 urinary tract,NS,papilloma,inverted c.1236C>T p.H412H 4:1804490-1804490 0

Expression for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Search GEO for disease gene expression data for Urinary Tract Papillary Transitional Cell Benign Neoplasm.

Pathways for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Pathways related to Urinary Tract Papillary Transitional Cell Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.65 FGFR3 MSH6 TERT TP53
2
Show member pathways
11.54 FGFR3 TERT TP53
3 11.23 FGFR3 TP53
4 11.18 MSH6 TP53
5 11.07 FGFR3 TP53
6 10.62 MSH6 TP53

GO Terms for Urinary Tract Papillary Transitional Cell Benign Neoplasm

Biological processes related to Urinary Tract Papillary Transitional Cell Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intrinsic apoptotic signaling pathway GO:0097193 9.26 MSH6 TP53
2 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.16 TERT TP53
3 determination of adult lifespan GO:0008340 8.96 MSH6 TP53
4 replicative senescence GO:0090399 8.62 TERT TP53

Sources for Urinary Tract Papillary Transitional Cell Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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