Aliases & Classifications for Uterine Anomalies

MalaCards integrated aliases for Uterine Anomalies:

Name: Uterine Anomalies 57
Uterine Diseases 54 42 44 70
Uterine Disease 12 15
Uterine Abnormality 54

Characteristics:

OMIM®:

57 (Updated 20-May-2021)
Inheritance:
autosomal dominant


HPO:

31
uterine anomalies:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:345
OMIM® 57 192000
ICD9CM 34 621.9
MeSH 44 D014591
NCIt 50 C26907
SNOMED-CT 67 237068005
ICD10 32 N85.9
MedGen 41 C0266383
SNOMED-CT via HPO 68 263681008 31401003
UMLS 70 C0042131

Summaries for Uterine Anomalies

MedlinePlus : 42 The uterus, or womb, is the place where a baby grows when a woman is pregnant. The first sign of a problem with the uterus may be bleeding between periods or after sex. Causes can include hormones, thyroid problems, fibroids, polyps, cancer, infection, or pregnancy. Treatment depends on the cause. Sometimes birth control pills treat hormonal imbalances. If a thyroid problem is the cause, treating it may also stop the bleeding. If you have cancer or hyperplasia, an overgrowth of normal cells in the uterus, you may need surgery. With two other uterine problems, tissue that normally lines the uterus grows where it is not supposed to. In endometriosis, it grows outside the uterus. In adenomyosis, it grows in the uterus's outside walls. Pain medicine may help. Other treatments include hormones and surgery.

MalaCards based summary : Uterine Anomalies, also known as uterine diseases, is related to cervix disease and endometriosis, and has symptoms including pelvic pain An important gene associated with Uterine Anomalies is MIR199A1 (MicroRNA 199a-1), and among its related pathways/superpathways are MicroRNAs in cancer and miRNA targets in ECM and membrane receptors. The drugs Hyaluronic acid and Mepivacaine have been mentioned in the context of this disorder. Affiliated tissues include uterus, cervix and thyroid, and related phenotype is bicornuate uterus.

Disease Ontology : 12 A female reproductive system disease that is located in the uterus.

More information from OMIM: 192000

Related Diseases for Uterine Anomalies

Diseases in the Uterine Anomalies family:

Uterine Inflammatory Disease

Diseases related to Uterine Anomalies via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 263)
# Related Disease Score Top Affiliating Genes
1 cervix disease 32.0 MIR9-1 MIR34A MIR31 MIR214 MIR21 MIR205
2 endometriosis 30.8 MIR200B MIR200A MIR199A1 MIR145 MIR143 MIR141
3 endometrial adenocarcinoma 30.5 MIR34A MIR200A ESR1
4 endometrial cancer 30.5 MIR34A MIR31 MIR205 MIR200B MIR200A MIR199A1
5 leiomyoma, uterine 30.4 MIR34A MIR21 MIR139 ESR1 CYP19A1
6 vaginal discharge 30.0 ESR1 CYP19A1
7 acrorenal-mandibular syndrome 10.9
8 pyometritis 10.9
9 endometrial disease 10.9
10 female infertility of uterine origin 10.9
11 uterine inflammatory disease 10.9
12 chronic subinvolution of uterus 10.9
13 placenta disease 10.9
14 hemometra 10.9
15 uterine inversion 10.9
16 endometriosis of ovary 10.6 MIR9-1 MIR145 MIR141 HNF1B ESR1 CYP19A1
17 esophagus adenocarcinoma 10.6 MIR21 MIR199A1 MIR196A1 MIR145 MIR143
18 bone resorption disease 10.6 MIR214 MIR199A1 MIR196A1 H2AC18 ESR1 CYP19A1
19 cervix small cell carcinoma 10.6 MIR199A1 MIR145 MIR143
20 ovarian serous carcinoma 10.6 MIR214 MIR21 MIR200B MIR200A MIR199A1 MIR145
21 pre-malignant neoplasm 10.6 MIR17 MIR143 MIR139 H2AC18 ESR1 CYP19A1
22 in situ carcinoma 10.6 MIR17 MIR143 MIR139 H2AC18 ESR1 CYP19A1
23 breast carcinoma in situ 10.6 MIR143 H2AC18 ESR1 CYP19A1
24 autonomic nervous system neoplasm 10.6 MIR9-1 MIR34A MIR21 MIR199A1 MIR196A1 MIR17
25 peripheral nervous system neoplasm 10.6 MIR9-1 MIR34A MIR21 MIR199A1 MIR196A1 MIR17
26 cervix carcinoma 10.6 MIR214 MIR200A MIR199A1 MIR141 H2AC18 ESR1
27 leukocyte disease 10.6 MIR21 MIR200B MIR199A1 MIR196A1 MIR17 H2AC18
28 autoimmune disease of musculoskeletal system 10.6 MIR34A MIR21 MIR199A1 MIR196A1 MIR17 H2AC18
29 inherited metabolic disorder 10.6 MIR9-1 MIR34A MIR21 MIR199A1 MIR196A1 MIR17
30 muscle cancer 10.6 MIR9-1 MIR199A1 MIR196A1 H2AC18
31 bone inflammation disease 10.6 MIR34A MIR21 MIR199A1 MIR196A1 MIR17 H2AC18
32 mature b-cell neoplasm 10.6 MIR9-1 MIR199A1 MIR196A1 MIR17 H2AC18
33 retinal vascular disease 10.6 MIR21 MIR199A1 MIR17 H2AC18
34 muscular disease 10.6 MIR9-1 MIR21 MIR199A1 MIR196A1 H2AC18
35 infratentorial cancer 10.6 MIR9-1 MIR199A1 MIR196A1 MIR17 H2AC18
36 autosomal genetic disease 10.6 MIR9-1 MIR21 MIR199A1 MIR196A1 MIR17 H2AC18
37 tonsil cancer 10.6 MIR199A1 H2AC18 ESR1
38 intestinal benign neoplasm 10.6 MIR21 MIR199A1 MIR196A1 MIR17 MIR15A MIR145
39 retinal cancer 10.6 MIR9-1 MIR214 MIR199A1 MIR196A1 MIR17 H2AC18
40 overnutrition 10.6 MIR34A MIR21 MIR199A1 MIR196A1 MIR17 H2AC18
41 bone marrow cancer 10.6 MIR9-1 MIR34A MIR21 MIR199A1 MIR196A1 MIR17
42 ocular cancer 10.6 MIR9-1 MIR214 MIR199A1 MIR196A1 MIR17 MIR143
43 heart valve disease 10.6 MIR21 MIR205 MIR199A1 MIR17 H2AC18
44 glucose metabolism disease 10.6 MIR9-1 MIR21 MIR199A1 MIR196A1 MIR17 MIR141
45 bile duct disease 10.6 MIR9-1 MIR199A1 MIR196A1 MIR17 MIR145 MIR139
46 uterine benign neoplasm 10.6 H2AC18 ESR1 CYP19A1
47 acquired metabolic disease 10.6 MIR9-1 MIR34A MIR21 MIR200A MIR199A1 MIR196A1
48 integumentary system disease 10.6 MIR9-1 MIR31 MIR21 MIR199A1 MIR196A1 MIR17
49 ovary epithelial cancer 10.6 MIR9-1 MIR21 MIR200A MIR199A1 MIR196A1 MIR17
50 bone remodeling disease 10.6 MIR214 MIR199A1 H2AC18 ESR1

Graphical network of the top 20 diseases related to Uterine Anomalies:



Diseases related to Uterine Anomalies

Symptoms & Phenotypes for Uterine Anomalies

Human phenotypes related to Uterine Anomalies:

31
# Description HPO Frequency HPO Source Accession
1 bicornuate uterus 31 HP:0000813

Symptoms via clinical synopsis from OMIM®:

57 (Updated 20-May-2021)
G U:
uterine anomalies
uterus arcuatus
uterus bicornis unicollis

Clinical features from OMIM®:

192000 (Updated 20-May-2021)

UMLS symptoms related to Uterine Anomalies:


pelvic pain

Drugs & Therapeutics for Uterine Anomalies

Drugs for Uterine Anomalies (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 44)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
2
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
3
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
4
tannic acid Approved Phase 4 1401-55-4
5
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
6
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
7 Viscosupplements Phase 4
8 Adjuvants, Immunologic Phase 4
9 Protective Agents Phase 4
10 Immunologic Factors Phase 4
11 Anesthetics Phase 4
12 Pharmaceutical Solutions Phase 4
13 Anesthetics, Local Phase 4
14 Hormone Antagonists Phase 4
15 Follicle Stimulating Hormone Phase 4
16 Antirheumatic Agents Phase 4
17 Anti-Inflammatory Agents Phase 4
18 Anti-Inflammatory Agents, Non-Steroidal Phase 4
19 Analgesics Phase 4
20 Cyclooxygenase Inhibitors Phase 4
21 Analgesics, Non-Narcotic Phase 4
22
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
23
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
24
Progesterone Approved, Vet_approved Phase 2 57-83-0 5994
25
Ofloxacin Approved Phase 2 82419-36-1 4583
26
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
27
Levofloxacin Approved, Investigational Phase 2 100986-85-4 149096
28 Antimitotic Agents Phase 2
29 Albumin-Bound Paclitaxel Phase 2
30 Tubulin Modulators Phase 2
31 Soy Bean Phase 2
32 Estrogens Phase 2
33 Estrogens, Conjugated (USP) Phase 2
34 Hormones Phase 2
35 Antiparasitic Agents Phase 2
36 Anti-Bacterial Agents Phase 2
37 Antimalarials Phase 2
38 Antiprotozoal Agents Phase 2
39 Anti-Infective Agents Phase 2
40
Povidone-iodine Approved 25655-41-8
41
Lidocaine Approved, Vet_approved 137-58-6 3676
42
Imidacloprid Vet_approved 105827-78-9 86418
43 Hematinics
44 Epoetin alfa 113427-24-0

Interventional clinical trials:

(show all 45)
# Name Status NCT ID Phase Drugs
1 Effectiveness of Self-cross-linked Hyaluronic Acid Gel in the Prevention of Intrauterine Adhesions After Second Trimester Abortion Unknown status NCT02868437 Phase 4
2 Randomized Double-blind Placebo Controlled Trial to Assess the Role of Intrauterine Cornual Block (ICOB) in Combination With Direct Cervical Block in Outpatient Endometrial Ablation Completed NCT01808898 Phase 4
3 How do Different Ovarian Stimulation Protocols Affect Endometrial Receptivity During a Fresh In-vitro Fertilization Attempt Recruiting NCT03755973 Phase 4 CFA;rFSH
4 Mechanistic Characterization of Uterine Pain (MCUP) to Improve Diagnosis and Treatment for Dysmenorrhea Recruiting NCT04145518 Phase 4 Naproxen Sodium
5 3D Sonohysterography vs Hysteroscopy: Study for the Evaluation of Intrauterine Abnormalities Unknown status NCT02682433 Phase 3
6 Impact of Opportunistic Salpingectomy on Ovarian Reserve in Patients Undergoing Laparoscopic Hysterectomy: a Multi-center, Randomized Controlled Trial Completed NCT01893086 Phase 3
7 A Randomized Comparison of Laparoendoscopic Single-site (LESS) Hysterectomies: Total Laparoscopic Hysterectomy (TLH) Versus Laparoscopically Assisted Vaginal Hysterectomy (LAVH) Completed NCT01861067 Phase 3
8 A Phase I/II, Open-Label, Multicenter, Two-Arm, Feasibility Study of Pazopanib, Carboplatin, and Paclitaxel in Women With Newly Diagnosed, Previously Untreated, Gynaecological Tumors Completed NCT00561795 Phase 2 pazopanib (GW786034);carboplatin;paclitaxel
9 Soy Estrogen Alternative Study (SEA) Completed NCT00000612 Phase 2 estrogens, conjugated
10 SIRT1-1 Antagonist Therapy Before Embryo Transfer to Improve Endometrial Receptivity and Life Pregnancy Rates Not yet recruiting NCT04184323 Phase 2 EX-527 (Selisistat);Placebo
11 Comparative Controlled Trial of Treatment of Minor Unexpected Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy Screening in Women Indicated for IVF Terminated NCT00830401 Phase 2 Ofloxacinum/Doxycycline
12 Intervention Study to Measure the Effect on Perception of Pain and Anxiety in Women With Indication for Diagnostic Hysteroscopy Through the Use of Virtual Reality Unknown status NCT03827824
13 Assessment of Feasibility and Benefit of the Use of Less Than 3 Millimeter Diameter's Instruments Compared to Standard Size Instruments in Laparoscopic Hysterectomy: a Randomized Single-center Comparative Study Unknown status NCT02367703
14 Prospective Randomized Comparison of Single-port and Three-port Laparoscopic Assisted Vaginal Hysterectomy Unknown status NCT01679548
15 Incidence and Pattern of Overactive Bladder Symptoms Occurring After Hysterectomy Unknown status NCT01683890
16 Prevalence of Congenital Uterine Malformations in Women With a History of Preterm Delivery or Miscarriage Unknown status NCT01487616
17 Clinical Advantages of Performing Concomitant Office Hysteroscopy and Endometrial Biopsy in Patients With Oligomenorrhea Seeking Infertility Treatment as Compared to Only Endometrial Biopsy: A Prospective Randomized Study Unknown status NCT03545945
18 Systematic And Standardized Hysteroscopic Endometrial Injury For Treatment Of Recurrent Implantation Failure Unknown status NCT03748238
19 Intrauterine Saline Washing for Detection Endometrial Disease in Patients With Abnormal Uterine Bleeding Unknown status NCT02691715
20 Study of Diagnosis of Color Power Doppler Combined Minimally Invasive Sampling for Endometrial Diseases Unknown status NCT03289468
21 Hysterectomy for Benign Gynaecological Disease by Natural Orifice Transluminal Endoscopic Surgery or Laparoscopy Completed NCT02631837
22 The Effect of Trendelenburg Lithotomy Position on Pain and Procedural Time During Vaginoscopic Office Hysteroscopy Completed NCT04436354
23 Do müllerian Anomalies Affect Embryo Implantation? Completed NCT04571671
24 Comparison of Total Laparoscopic Hysterectomy and Laparoscopic Assisted Vaginal Hysterectomy With Over Giant Uterus of Than 500g: A Randomized Controlled Trial Completed NCT03146299
25 A Retrospective Analysis of a Complete Enseal Laparoscopic Vaginal Assisted Hysterectomy Versus a Traditional Suture Laparoscopic Vaginal Hysterectomy Completed NCT01217866
26 Randomized Clinical Trial of Total Versus Subtotal Abdominal Hysterectomy Completed NCT01880710
27 Disposable Energy Sources and Operating Room Time for Laparoscopic Hysterectomy Completed NCT02065453
28 Postoperative Pain After Total Laparoscopic Hysterectomy: a Comparison of Transumbilical Single-port Access and Conventional Three-port Laparoscopic Surgery Completed NCT02390804
29 Fast Versus Slow Tenaculum Placement for Office Procedures: A Randomized Controlled Trial Completed NCT02716636
30 Deep Dive Randomized Control Trial Completed NCT00793260
31 Endometrial and Isthmic Microbiota During IVF Stimulation in Patients Affected With Isthmocele and Intrauterine Mucus Secretion After C-section. Completed NCT03519763
32 REM (Risk Of Endometrial Malignancy): A Proposal for a New Scoring System to Evaluate Risk of Endometrial Malignancy Completed NCT01830192
33 Breast, Ovarian and Endometrial Cancer Case-Control Study in Poland Completed NCT00341458
34 Pilot Study: Can the iKnife (Rapid Evaporative Ionisation Mass Spectrometry) Distinguish Between Normal and Malignant Endometrial Tissue? Completed NCT03207074
35 Robotic Assisted Surgery for Treatment of Gynecological Diseases: Pilot Study Completed NCT03093675
36 Proliferative Effects of Erythropoietin on Human Endometrium Completed NCT03060603 Erythropoietin
37 Comparative Prospective Data Collection in Connection With Two Different Treatment Methods: Robotic Assisted Laparoscopy and Conventional Laparoscopy Recruiting NCT03861195
38 Feasibility Assessment of Assisted Laparoscopic-robotic Hysterectomy for Uterine Transplantation in Live-donor Patient. Description of the Donor and Recipient Surgical Technique. Recruiting NCT04249791
39 Induction of Labor in Women With Unfavorable Cervix: Randomized Controlled Trial Comparing Outpatient to Inpatient Cervical Ripening Using Dilapan-S® (HOMECARE) Recruiting NCT03665688
40 Prospective Clinical Study of the Relationship Between Cancer Driving Mutations Found in Endometriotic Implants and the Development of Progesterone Resistance Recruiting NCT03756480
41 Can SMS-reminders Result in Increased Participation in Cervical Screening? Recruiting NCT04061967
42 Self-Testing Options in the Era of Primary HPV Screening for Cervical Cancer: the STEP Trial Enrolling by invitation NCT04679675
43 Efficacy of At-origin Uterine Artery Ligation Compared to Conventional Post-cornual Pedicle Ligation in Reducing Operative Time During Total Laparoscopic Hysterectomy Not yet recruiting NCT04808583
44 Congenital Uterine Anomalies: Identifying Cancer Associations and Genetic and Environmental Factors to Improve Clinical Care Not yet recruiting NCT04661072
45 Cervical Cerclage Position Throughout Pregnancy, it's Distance From the Inner and Outer Cervical os', and Implications of the Position on Pregnancy Outcomes. Terminated NCT03046654

Search NIH Clinical Center for Uterine Anomalies

Inferred drug relations via UMLS 70 / NDF-RT 51 :


CARBOXYMETHYLCELLULOSE CALCIUM

Cochrane evidence based reviews: uterine diseases

Genetic Tests for Uterine Anomalies

Anatomical Context for Uterine Anomalies

The Foundational Model of Anatomy Ontology organs/tissues related to Uterine Anomalies:

19
Uterus

MalaCards organs/tissues related to Uterine Anomalies:

40
Uterus, Cervix, Thyroid, Ovary, Bone, Placenta, Breast

Publications for Uterine Anomalies

Articles related to Uterine Anomalies:

(show top 50) (show all 792)
# Title Authors PMID Year
1
Familial bicornuate and double uterus. 57
4841581 1974
2
[On the problem of frequent familial occurrence of uterus abnormalities]. 57
5997716 1966
3
Observations on the results of pregnancies in women resident in Belfast. II. Abortions, hydatidiform moles and ectopic pregnancies. 57
13834545 1959
4
Congenital abnormalities of the uterus and pregnancy. 57
13316096 1956
5
UTERUS DIDELPHYS. 57
20320870 1938
6
Intrauterine infusion of platelet-rich plasma is a treatment method for patients with intrauterine adhesions after hysteroscopy. 42
32816322 2020
7
A New Thermo-Responsive Hyaluronic Acid Sol-Gel to Prevent Intrauterine Adhesions after Hysteroscopic Surgery: A Randomized, Non-Inferiority Trial. 42
32975061 2020
8
Pregnancy outcomes after hysteroscopic surgery in women with cesarean scar syndrome. 42
33270754 2020
9
Pregnancy in the blind hemi-cavity of Robert's uterus: a case report. 61
33717388 2021
10
Importance of transient myometrial contractions in diagnosis of adenomyosis and congenital uterine anomalies. 61
32250499 2021
11
Uterine didelphys: diagnosis, management and pregnancy outcome. 61
33782076 2021
12
Office hysteroscopy before first in vitro fertilization. A randomized controlled trial. 61
33727208 2021
13
Uterine factors in recurrent pregnancy losses. 61
33712099 2021
14
Benign Uterine Disease: The Added Role of Imaging. 61
33573786 2021
15
Associations between days on close-up diets and immune responses prepartum, metabolites peripartum, and risk of postpartum diseases in Jersey cows. 61
33773790 2021
16
Predicting the risk of retained fetal membranes and metritis in dairy cows according to prepartum hemogram and immune and metabolic status. 61
33257005 2021
17
Levonorgestrel intrauterine system (IUS) in a patient with uterine didelphys: A case report. 61
33098848 2021
18
Female counterpart of the Zinner syndrome in men: decoding the 'OHVIRA' syndrome. 61
33568411 2021
19
17-hydroxyprogesterone caproate for women with congenital uterine anomalies: does it impact the risk of recurrent preterm birth? 61
33451616 2021
20
Live birth rate from euploid blastocysts is not associated with infertility etiology or oocyte source following frozen-thawed embryo transfer (FET): analysis of 4148 cycles reported to SART CORS. 61
33155088 2021
21
Abdominal cerclage in a patient with a neocervix with planned cesarean hysterectomy at delivery. 61
33084188 2021
22
The development of the human uterus: morphogenesis to menarche. 61
33395479 2021
23
Serum retinol, β-carotene, and α-tocopherol as biomarkers for disease risk and milk production in periparturient dairy cows. 61
33162081 2021
24
[Clinical cohort study of total hysterectomy via transvaginal natural orifice transluminal endoscopic surgery and transumbilical laparoendoscopic single site surgery]. 61
33355759 2020
25
Efficacy of a vaginal tablet as a Persian medicine product on vulvovaginal candidiasis: a double-blind, randomised, placebo-controlled trial. 61
32615837 2020
26
Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer. 61
33010915 2020
27
A retrospective study of 323 total laparoscopic hysterectomy cases for various indications and a case report treating caesarean scar pregnancy. 61
33308278 2020
28
Postpartum uterine diseases negatively impact the time to pregnancy in grazing dairy cows from high-altitude tropical herds. 61
33186880 2020
29
Metabolomics for Diagnosis and Prognosis of Uterine Diseases? A Systematic Review. 61
33371433 2020
30
Diagnostic accuracy of hysteroscopy, ultrasound and magnetic resonance imaging in detecting congenital uterine anomalies. 61
33306285 2020
31
Uterine 'anomalies' by ESHRE/ESGE classification: are more than half of women really sick? 61
31994244 2020
32
Cervical length surveillance for predicting spontaneous preterm birth in women with uterine anomalies: A cohort study. 61
32438506 2020
33
The Trained Sniffer Dog Could Accurately Detect the Urine Samples from the Patients with Cervical Cancer, and Even Cervical Intraepithelial Neoplasia Grade 3: A Pilot Study. 61
33172075 2020
34
Assessment of the anti-inflammatory and engraftment potential of horse endometrial and adipose mesenchymal stem cells in an in vivo model of post breeding induced endometritis. 61
32622203 2020
35
The number of overall hysterectomies per population with the perimenopausal status is increasing in Japan: A national representative cohort study. 61
33029831 2020
36
Clinical Changes and Uterine Hemodynamic in Pyometra Medically Treated Bitches. 61
33142944 2020
37
Defining recurrent pregnancy loss: associated factors and prognosis in couples with two versus three or more pregnancy losses. 61
32811769 2020
38
Successful laparoscopic surgery of accessory cavitated uterine mass in young women with severe dysmenorrhea. 61
32942350 2020
39
Association of postpartum uterine diseases with lying time and metabolic profiles of multiparous Holstein dairy cows in the transition period. 61
32928490 2020
40
Interpreting body MRI cases: classic findings in pelvic MRI. 61
32607649 2020
41
Recent advances and future directions for uterine diseases diagnosis, pathogenesis, and management in dairy cows. 61
33029222 2020
42
Management of a twin pregnancy in a didelphys uterus: one fetus in each uterine cavity. 61
32843451 2020
43
Correct measurements of uterine fundal internal indentation depth and angle: an important but overlooked issue for precise diagnosis of uterine anomalies. 61
32851686 2020
44
GREB1L variants in familial and sporadic hereditary urogenital adysplasia and Mayer-Rokitansky-Kuster-Hauser syndrome. 61
32378186 2020
45
[Bovine uterine diseases: Aspects of microbiology, molecular biology, and immunology]. 61
32823330 2020
46
Recombinant protein subunit vaccine reduces puerperal metritis incidence and modulates the genital tract microbiome. 61
32505392 2020
47
Adaptive immunity in the postpartum uterus: Potential use of vaccines to control metritis. 61
31983466 2020
48
Surgical outcomes of hysterectomy by transvaginal natural orifice transluminal endoscopic surgery (vNOTES) compared with laparoscopic total hysterectomy (LTH) in women with non-prolapsed and benign uterine diseases. 61
32653130 2020
49
The association between adenomyosis and recurrent miscarriage. 61
32428805 2020
50
Twin pregnancy in a bicornuate uterus in rural Kenya: A case report for accidental discovery and successful delivery. 61
32787410 2020

Variations for Uterine Anomalies

Expression for Uterine Anomalies

Search GEO for disease gene expression data for Uterine Anomalies.

Pathways for Uterine Anomalies

GO Terms for Uterine Anomalies

Cellular components related to Uterine Anomalies according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 MIR31 MIR21 MIR205 MIR199A1 MIR17 MIR15A
2 extracellular vesicle GO:1903561 9.02 MIR34A MIR214 MIR21 MIR17 MIR15A

Biological processes related to Uterine Anomalies according to GeneCards Suite gene sharing:

(show all 31)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.95 MIR34A MIR214 MIR21 MIR200B MIR17 ESR1
2 positive regulation of protein kinase B signaling GO:0051897 9.91 MIR21 MIR199A1 MIR143 ESR1
3 positive regulation of angiogenesis GO:0045766 9.87 MIR31 MIR21 MIR199A1 MIR143
4 negative regulation of cell migration GO:0030336 9.85 MIR9-1 MIR34A MIR214 MIR21 MIR145
5 negative regulation of inflammatory response GO:0050728 9.8 MIR31 MIR205 MIR15A MIR145 MIR141
6 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.77 MIR214 MIR21 MIR17
7 negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 9.77 MIR199A1 MIR196A1 MIR15A
8 positive regulation of blood vessel endothelial cell migration GO:0043536 9.76 MIR31 MIR200A MIR143
9 negative regulation of vascular smooth muscle cell proliferation GO:1904706 9.73 MIR34A MIR214 MIR15A
10 negative regulation of cardiac muscle cell apoptotic process GO:0010667 9.7 MIR21 MIR199A1 MIR145
11 negative regulation of angiogenesis GO:0016525 9.7 MIR34A MIR214 MIR21 MIR200B MIR15A MIR145
12 positive regulation of connective tissue replacement GO:1905205 9.67 MIR34A MIR214 MIR199A1
13 negative regulation of cardiac muscle hypertrophy GO:0010614 9.65 MIR21 MIR145
14 regulation of smooth muscle contraction GO:0006940 9.65 MIR145 MIR143
15 negative regulation of vascular endothelial growth factor production GO:1904046 9.65 MIR34A MIR205 MIR199A1 MIR17 MIR15A
16 positive regulation of cardiac muscle cell apoptotic process GO:0010666 9.64 MIR34A MIR17
17 negative regulation of low-density lipoprotein particle clearance GO:0010989 9.64 MIR199A1 MIR17
18 negative regulation of leukocyte adhesion to vascular endothelial cell GO:1904995 9.63 MIR31 MIR141
19 negative regulation of vascular wound healing GO:0061044 9.63 MIR34A MIR200B
20 angiotensin-activated signaling pathway GO:0038166 9.62 MIR145 MIR143
21 negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460 9.62 MIR21 MIR17
22 negative regulation of vascular associated smooth muscle cell migration GO:1904753 9.62 MIR34A MIR214 MIR21 MIR15A
23 negative regulation of lamellipodium assembly GO:0010593 9.61 MIR214 MIR196A1
24 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.61 MIR214 MIR199A1 MIR17
25 aorta smooth muscle tissue morphogenesis GO:0060414 9.58 MIR145 MIR143
26 miRNA mediated inhibition of translation GO:0035278 9.56 MIR9-1 MIR31 MIR21 MIR205 MIR200B MIR17
27 positive regulation of pulmonary blood vessel remodeling GO:1905111 9.55 MIR17 MIR143
28 regulation of phenotypic switching GO:1900239 9.54 MIR145 MIR143
29 positive regulation of metalloendopeptidase activity GO:1904685 9.54 MIR21 MIR205 MIR17
30 gene silencing by miRNA GO:0035195 9.53 MIR9-1 MIR34A MIR31 MIR214 MIR21 MIR205
31 establishment or maintenance of cell type involved in phenotypic switching GO:0044663 9.51 MIR145 MIR143

Molecular functions related to Uterine Anomalies according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA 3'-UTR binding GO:0003730 9.73 MIR9-1 MIR34A MIR31 MIR21 MIR205 MIR200B
2 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.53 MIR9-1 MIR34A MIR31 MIR214 MIR21 MIR205

Sources for Uterine Anomalies

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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