MCID: UTR031
MIFTS: 29

Uterine Benign Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Uterine Benign Neoplasm

MalaCards integrated aliases for Uterine Benign Neoplasm:

Name: Uterine Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060095

Summaries for Uterine Benign Neoplasm

Disease Ontology : 12 A female reproductive organ benign neoplasm that is located in the uterus.

MalaCards based summary : Uterine Benign Neoplasm is related to endometrial stromal nodule and endometrial hyperplasia. An important gene associated with Uterine Benign Neoplasm is HPSE2 (Heparanase 2 (Inactive)), and among its related pathways/superpathways are Pathways in cancer and Gastric cancer. Affiliated tissues include uterus, and related phenotypes are Decreased TP53 mRNA expression and Decreased TP53 mRNA expression

Related Diseases for Uterine Benign Neoplasm

Diseases related to Uterine Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 289, show less)
# Related Disease Score Top Affiliating Genes
1 endometrial stromal nodule 32.7 MME CALD1
2 endometrial hyperplasia 32.3 TP53 PTEN PGR HOXA10 ESR2 ESR1
3 leiomyoma, uterine 32.0 PGR MED12 IGF1 HPSE2 HMGA2 GNRH1
4 uterine corpus adenomatoid tumor 11.3
5 uterine corpus bizarre leiomyoma 11.3
6 adenomyoma of uterine corpus 11.3
7 uterine corpus adenofibroma 11.3
8 uterine ligament papillary cystadenoma associated with von hippel-lindau disease 11.3
9 uterine corpus leiomyomatosis 11.3
10 uterine corpus cellular leiomyoma 11.3
11 glassy cell carcinoma of the cervix 10.7 PGR ESR1
12 bartholin's gland adenoid cystic carcinoma 10.7 PGR ESR1
13 chronic tympanitis 10.7 PGR ESR1
14 infertility due to extratesticular cause 10.7 GNRH1 ESR1
15 granulomatous endometritis 10.7 PGR ESR1
16 breast duct papilloma 10.7 PTEN PGR
17 vaginal glandular tumor 10.7 PGR ESR1
18 cervical adenomyoma 10.7 PGR MME
19 vulvar syringoma 10.7 PGR ESR1
20 trigonitis 10.7 PGR ESR1
21 liver adenomatosis 10.7 PGR CTNNB1
22 fat necrosis of breast 10.7 HMGA2 ESR1
23 fallopian tube endometriosis 10.7 PGR MME
24 cervical benign neoplasm 10.7 PGR MME
25 breast scirrhous carcinoma 10.7 PGR ESR1
26 nonmucinous bronchioloalveolar adenocarcinoma 10.7 ESR2 ESR1
27 vaginitis 10.7 ESR2 ESR1 EPPIN
28 oncocytic breast carcinoma 10.7 PGR ESR1
29 endometrial squamous cell carcinoma 10.7 TP53 PGR
30 cervical clear cell adenocarcinoma 10.7 PGR ESR1
31 bartholin's gland adenoma 10.7 TP53 PGR ESR1
32 bartholin's gland benign neoplasm 10.7 TP53 PGR ESR1
33 vestibular gland benign neoplasm 10.7 TP53 PGR ESR1
34 pulmonary vein leiomyosarcoma 10.7 PGR CALD1
35 cystadenocarcinoma 10.7 TP53 PGR ESR2
36 ovarian seromucinous carcinoma 10.7 TP53 PGR ESR1
37 adult type testicular granulosa cell tumor 10.7 PGR ESR1
38 cecum lymphoma 10.7 TP53 MME
39 comedo carcinoma 10.7 TP53 PGR ESR1
40 cervical serous adenocarcinoma 10.7 PGR MME
41 progesterone resistance 10.7 PGR ESR2 ESR1
42 vulvar benign neoplasm 10.7 PGR CALD1
43 atrophy of prostate 10.6 TP53 GNRH1 EPPIN
44 lung leiomyoma 10.6 PGR ESR1 CALD1
45 apocrine adenocarcinoma 10.6 TP53 PGR ESR1
46 breast leiomyoma 10.6 PGR MME FH
47 juvenile nasopharyngeal angiofibroma 10.6 PGR ESR1 CYP19A1
48 uterine corpus adenosarcoma 10.6 PGR MME ESR1
49 mixed endometrial stromal and smooth muscle tumor 10.6 MME CALD1
50 vaginal endometrial stromal tumor 10.6 MME CALD1
51 urethra leiomyoma 10.6 MME CALD1
52 luteoma 10.6 GNRH1 EPPIN CYP19A1
53 microglandular adenosis 10.6 TP53 PGR ESR1
54 basaloid lung carcinoma 10.6 TP53 PGR
55 vulvar intraepithelial neoplasia 10.6 TP53 CTNNB1
56 breast papillary carcinoma 10.6 PGR ESR1
57 breast metaplastic carcinoma 10.6 PGR MME ESR1
58 sweat gland disease 10.6 TP53 PGR ESR1
59 endometrial serous adenocarcinoma 10.6 TP53 PTEN PGR
60 sweat gland cancer 10.6 TP53 PGR ESR1
61 benign breast phyllodes tumor 10.6 PGR MME MED12
62 aromatase deficiency 10.6 GNRH1 ESR1 CYP19A1
63 benign metastasizing leiomyoma 10.6 PGR CYP19A1
64 breast osteosarcoma 10.6 PGR MME ESR1
65 intraductal breast benign neoplasm 10.6 PGR MME ESR1
66 apocrine adenosis of breast 10.6 TP53 PGR
67 liver leiomyoma 10.6 PGR ESR1
68 adhesions of uterus 10.6 PGR HOXA10 AMH
69 short syndrome 10.6 TP53 PGR ESR1
70 pelvic varices 10.6 GNRH1 EPPIN AMH
71 bile duct cystadenoma 10.6 ESR2 ESR1
72 tonsil cancer 10.6 TP53 PGR ESR1
73 endocervical adenocarcinoma 10.6 TP53 PGR ESR1
74 testicular torsion 10.6 TP53 EPPIN AMH
75 mulchandani-bhoj-conlin syndrome 10.6 PGR MME ESR1
76 infiltrating angiolipoma 10.6 HMGA2 GNRH1 CALD1
77 breast sarcoma 10.6 TP53 PGR MME
78 lung combined type small cell carcinoma 10.6 MME CALD1
79 wolffian duct adenocarcinoma 10.6 TP53 MME ESR1
80 steroid inherited metabolic disorder 10.6 GNRH1 CYP19A1 AMH
81 vaginal adenoma 10.6 ESR2 CYP19A1 CTNNB1
82 breast myofibroblastoma 10.6 MME ESR1 CALD1
83 vaginal benign neoplasm 10.6 ESR2 CYP19A1 CTNNB1
84 cervical polyp 10.6 PGR MME CALD1
85 sweat gland benign neoplasm 10.6 TP53 PGR MME
86 leydig cell tumor 10.6 GNRH1 ESR1 CYP19A1
87 endometrioid ovary carcinoma 10.6 TP53 PTEN CTNNB1
88 subareolar duct papillomatosis 10.6 MME CALD1
89 large intestine adenocarcinoma 10.6 TP53 PTEN CTNNB1
90 bilateral breast cancer 10.6 PTEN PGR ESR1
91 amelogenesis imperfecta 10.6 PGR ESR2 ESR1 CYP19A1
92 subserous uterine fibroid 10.6 PGR HPSE2 CYP19A1 AMH
93 intravascular fasciitis 10.6 ESR1 CTNNB1 CALD1
94 adult cystic nephroma 10.6 PGR MME
95 nipple benign neoplasm 10.6 MME CALD1
96 cellular leiomyoma 10.6 MME MED12 CALD1
97 gastric leiomyoma 10.6 FH CALD1
98 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.6 TSC2 PTEN HMGA2
99 vaginal discharge 10.6 PGR GNRH1 ESR1 CYP19A1
100 central precocious puberty 10.6 IGF1 GNRH1
101 prostatic hypertrophy 10.6 PGR ESR1 EPPIN CYP19A1
102 diffuse peritoneal leiomyomatosis 10.6 PGR MED12 GNRH1 CALD1
103 gender identity disorder 10.6 PGR ESR2 ESR1 CYP19A1
104 endometrial disease 10.6 PGR GNRH1 ESR1 CYP19A1
105 peritoneal benign neoplasm 10.6 PGR MED12 GNRH1 CALD1
106 progesterone-receptor positive breast cancer 10.6 PGR ESR2 ESR1 CYP19A1
107 respiratory system benign neoplasm 10.6 TP53 PTEN CTNNB1
108 uterine corpus endometrial carcinoma 10.6 TP53 PTEN CTNNB1
109 adrenal cortex disease 10.6 TP53 EPPIN CTNNB1
110 adrenal cortical carcinoma 10.6 TP53 EPPIN CTNNB1
111 ovarian hyperstimulation syndrome 10.6 GNRH1 CYP19A1 AMH
112 conventional fibrosarcoma 10.6 TP53 CTNNB1 CALD1
113 lipomatosis, multiple 10.6 PTEN HMGA2 CALD1
114 pelvic organ prolapse 10.6 TP53 PGR ESR2 ESR1
115 kidney benign neoplasm 10.6 TSC2 MME FH
116 fallopian tube carcinoma 10.6 TP53 PTEN PGR ESR1
117 ovarian cystadenocarcinoma 10.6 TP53 PTEN CTNNB1
118 premenstrual tension 10.6 PGR GNRH1
119 ovarian benign neoplasm 10.6 TP53 GNRH1 EPPIN AMH
120 mucinous adenocarcinoma 10.6 TP53 PGR ESR2 ESR1
121 postmenopausal atrophic vaginitis 10.6 ESR2 ESR1 CYP19A1 AMH
122 premature menopause 10.6 GNRH1 EPPIN CYP19A1 AMH
123 cervical adenocarcinoma 10.6 TP53 PTEN PGR ESR1
124 fallopian tube leiomyoma 10.6 TSC2 MME CALD1
125 fallopian tube benign neoplasm 10.6 TSC2 MME CALD1
126 oropharynx cancer 10.6 TP53 PGR CTNNB1
127 mammographic density 10.6 PGR IGF1 ESR1 CYP19A1
128 sebaceous gland disease 10.6 IGF1 GNRH1 AMH
129 endocervical carcinoma 10.6 TP53 PGR ESR1 CTNNB1
130 androgenic alopecia 10.6 IGF1 CYP19A1 CTNNB1
131 leiomyomatosis 10.6 PGR MED12 GNRH1 FH ESR1
132 well-differentiated liposarcoma 10.6 TP53 HMGA2 CALD1
133 skin sarcoma 10.6 FH CALD1
134 cystadenoma 10.6 PTEN PGR MME FH
135 adenosarcoma 10.5 TP53 PGR MME ESR1
136 ovarian clear cell adenocarcinoma 10.5 TP53 PGR HOXA10 ESR2
137 uterus perivascular epithelioid cell tumor 10.5 TSC2 MME CALD1
138 adenosquamous carcinoma 10.5 TP53 PTEN PGR
139 ovarian cyst 10.5 GNRH1 ESR2 CYP19A1 AMH
140 testicular disease 10.5 TP53 GNRH1 EPPIN AMH
141 pleomorphic lipoma 10.5 PGR HMGA2
142 vaginal endometrial stromal sarcoma 10.5 PGR MME ESR1 CALD1
143 uterine body mixed cancer 10.5 TP53 PTEN ESR1 CTNNB1
144 varicocele 10.5 TP53 GNRH1 AMH
145 vagina sarcoma 10.5 PGR MME ESR1 CALD1
146 ectopic pregnancy 10.5 PGR HOXA10 GNRH1
147 adrenal gland disease 10.5 TP53 IGF1 EPPIN
148 pseudohermaphroditism 10.5 EPPIN CYP19A1 AMH
149 atypical teratoid rhabdoid tumor 10.5 TP53 HMGA2 CTNNB1
150 lipoid congenital adrenal hyperplasia 10.5 GNRH1 CYP19A1 AMH
151 tubular adenocarcinoma 10.5 PGR MME ESR1 CTNNB1
152 ovarian endometrioid stromal sarcoma 10.5 PGR MME CYP19A1 CALD1
153 endometrial stromal tumor 10.5 PGR MME ESR1 CALD1
154 46,xy sex reversal 10.5 GNRH1 ESR1 CYP19A1 AMH
155 cutaneous leiomyosarcoma 10.5 FH CALD1
156 cardiovascular organ benign neoplasm 10.5 TP53 PTEN CTNNB1
157 neurofibromatosis, type ii 10.5 TP53 PTEN PGR CTNNB1
158 liposarcoma 10.5 TP53 PTEN HMGA2 CTNNB1
159 birt-hogg-dube syndrome 10.5 TSC2 PTEN FH CTNNB1
160 dedifferentiated liposarcoma 10.5 TP53 PTEN HMGA2 CALD1
161 sarcomatoid squamous cell skin carcinoma 10.5 MME CALD1
162 li-fraumeni syndrome 10.5 TP53 PTEN ESR1 CTNNB1
163 angiomyolipoma 10.5 TSC2 PGR MME ESR1
164 atypical polypoid adenomyoma 10.5 MME MED12 CTNNB1 CALD1
165 anovulation 10.5 IGF1 GNRH1 CYP19A1 AMH
166 gynecomastia 10.5 PGR GNRH1 ESR2 ESR1 CYP19A1
167 hypertrophy of breast 10.5 TP53 PTEN PGR ESR1 CYP19A1
168 tuberous sclerosis 2 10.5 TSC2 PTEN IGF1
169 mccune-albright syndrome 10.5 IGF1 CYP19A1 AMH
170 mesenchymal cell neoplasm 10.5 TP53 MME HMGA2 CALD1
171 luminal breast carcinoma a 10.5 TP53 PTEN PGR ESR1 CYP19A1
172 lipid-rich carcinoma 10.5 PGR ESR1
173 breast malignant phyllodes tumor 10.5 TP53 PGR MME MED12 ESR1
174 endocrine organ benign neoplasm 10.5 TP53 IGF1 FH CTNNB1
175 ureteral obstruction 10.5 TP53 GNRH1 CTNNB1
176 estrogen-receptor positive breast cancer 10.5 TP53 PGR ESR2 ESR1 CYP19A1
177 thoracic benign neoplasm 10.5 TP53 PGR MME MED12 ESR1
178 breast benign neoplasm 10.5 TP53 PGR MME MED12 ESR1
179 perivascular epithelioid cell tumor 10.5 TSC2 PGR MME CALD1
180 tongue squamous cell carcinoma 10.5 TP53 PTEN HMGA2 CTNNB1
181 female reproductive endometrioid cancer 10.5 TP53 PTEN PGR ESR1 CTNNB1
182 breast adenocarcinoma 10.5 TP53 PGR MED12 HMGA2 ESR1
183 leiomyoma cutis 10.5 MED12 FH
184 uterine corpus cancer 10.5 TP53 PTEN PGR ESR1 CTNNB1
185 primary pigmented nodular adrenocortical disease 10.5 PGR ESR2 ESR1 CYP19A1 CTNNB1
186 intestinal benign neoplasm 10.5 TP53 PTEN CTNNB1
187 retinitis pigmentosa 11 10.5 TP53 PTEN MIR146A
188 infratentorial cancer 10.5 TP53 PTEN CTNNB1
189 ovary adenocarcinoma 10.5 TP53 PTEN PGR ESR1 CTNNB1
190 serous cystadenocarcinoma 10.5 TP53 PTEN PGR ESR2 CTNNB1
191 breast carcinoma in situ 10.5 TP53 PGR ESR1 CYP19A1 CTNNB1
192 ovary epithelial cancer 10.5 TP53 PTEN PGR ESR1 CTNNB1
193 amenorrhea 10.5 IGF1 GNRH1 CYP19A1
194 malignant ovarian surface epithelial-stromal neoplasm 10.5 TP53 PTEN PGR ESR1 CTNNB1
195 aromatase excess syndrome 10.5 IGF1 ESR2 ESR1 EPPIN CYP19A1
196 vulvar leiomyoma 10.5 PGR MME HMGA2 ESR1 CALD1
197 teeth hard tissue disease 10.5 PGR IGF1 ESR2 ESR1 CYP19A1
198 polycystic ovary syndrome 10.5 IGF1 GNRH1 CYP19A1 AMH
199 male infertility 10.5 GNRH1 ESR2 ESR1 EPPIN CYP19A1
200 pleomorphic adenoma 10.5 TP53 HMGA2 CTNNB1
201 uterine anomalies 10.5 TP53 MIR146A ESR1 CYP19A1
202 female breast cancer 10.5 TP53 PGR IGF1 ESR1 CYP19A1
203 cardiovascular cancer 10.5 TSC2 TP53 MME CALD1
204 vascular cancer 10.5 TSC2 TP53 MME CALD1
205 pituitary adenoma, prolactin-secreting 10.5 IGF1 HMGA2 GNRH1 ESR2 ESR1
206 urethral benign neoplasm 10.5 TP53 PGR MME ESR1 CALD1
207 hyperandrogenism 10.5 IGF1 GNRH1 CYP19A1
208 carcinosarcoma 10.4 TP53 PTEN PGR MME CTNNB1
209 cervical adenoma malignum 10.4 TP53 PGR MME HMGA2 CALD1
210 estrogen-receptor negative breast cancer 10.4 PGR IGF1 ESR1 CYP19A1 CTNNB1
211 leiomyosarcoma 10.4 TP53 PGR MED12 HMGA2 FH ESR1
212 breast adenoid cystic carcinoma 10.4 TP53 PGR
213 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 10.4 TSC2 TP53 PTEN CTNNB1
214 teratoma 10.4 TP53 PTEN ESR1 CTNNB1 AMH
215 lymphangioleiomyomatosis 10.4 TSC2 PGR IGF1 GNRH1 ESR1
216 tuberous sclerosis 10.4 TSC2 TP53 PTEN IGF1
217 bile duct adenocarcinoma 10.4 TP53 PTEN CTNNB1
218 bizarre leiomyoma 10.4 TP53 PGR MED12 FH ESR1 CALD1
219 bone resorption disease 10.4 IGF1 ESR2 ESR1 CYP19A1 CTNNB1
220 bone remodeling disease 10.4 IGF1 ESR2 ESR1 CYP19A1 CTNNB1
221 renal cell carcinoma, papillary, 1 10.4 TP53 PTEN MME FH CTNNB1
222 pancreatic ductal adenocarcinoma 10.4 TP53 PTEN MIR146A CTNNB1
223 cowden syndrome 10.4 TSC2 TP53 PTEN FH CTNNB1
224 dermis tumor 10.4 MED12 FH
225 hemangioma 10.4 TSC2 TP53 PTEN PGR CTNNB1
226 mantle cell lymphoma 10.4 TP53 PTEN MME CTNNB1
227 pleomorphic adenoma carcinoma 10.4 TP53 HMGA2
228 peutz-jeghers syndrome 10.4 TSC2 TP53 PTEN CYP19A1 CTNNB1
229 tongue disease 10.4 TP53 PTEN CTNNB1
230 intravenous leiomyomatosis 10.4 PGR MME MED12 HMGA2 ESR1 CALD1
231 amelogenesis imperfecta, type ig 10.4 PGR IGF1 GNRH1 ESR2 ESR1 CYP19A1
232 lobular neoplasia 10.4 TP53 PGR ESR2 ESR1 CYP19A1 CTNNB1
233 pre-malignant neoplasm 10.4 TP53 PTEN PGR ESR1 CYP19A1 CTNNB1
234 in situ carcinoma 10.4 TP53 PTEN PGR ESR1 CYP19A1 CTNNB1
235 ovarian serous cystadenocarcinoma 10.4 TP53 PTEN PGR ESR2 ESR1 CTNNB1
236 infertility 10.4 PGR HOXA10 GNRH1 ESR2 EPPIN CYP19A1
237 intrahepatic cholangiocarcinoma 10.4 TP53 PTEN CTNNB1
238 central nervous system benign neoplasm 10.4 TSC2 TP53 PTEN IGF1 CTNNB1
239 clear cell renal cell carcinoma 10.4 TP53 PTEN MME FH CTNNB1
240 vaginal cancer 10.4 TP53 PGR MME ESR2 ESR1 CALD1
241 connective tissue benign neoplasm 10.4 TSC2 TP53 MME CTNNB1 CALD1
242 estrogen excess 10.4 PTEN PGR GNRH1 ESR2 ESR1 EPPIN
243 cardiovascular system disease 10.4 MME MIR146A IGF1 ESR2 ESR1
244 craniopharyngioma 10.4 IGF1 GNRH1 CTNNB1
245 meningioma, familial 10.3 TP53 PTEN PGR IGF1 ESR1 CTNNB1
246 lynch syndrome 10.3 TP53 PTEN IGF1 CTNNB1
247 endometriosis of ovary 10.3 PTEN PGR GNRH1 ESR2 ESR1 CYP19A1
248 smooth muscle tumor 10.3 PGR MME MED12 HMGA2 FH ESR1
249 glandular cystitis 10.3 TP53 CTNNB1
250 hypogonadotropic hypogonadism 23 without anosmia 10.3 GNRH1 EPPIN
251 breast fibroadenoma 10.3 TP53 PGR MME MED12 HMGA2 ESR1
252 sporadic breast cancer 10.3 TP53 PTEN PGR MIR146A ESR2 ESR1
253 breast ductal carcinoma 10.3 TP53 PTEN PGR ESR2 ESR1 CYP19A1
254 ductal carcinoma in situ 10.3 TP53 PTEN PGR MME ESR2 ESR1
255 gastric adenocarcinoma 10.3 TP53 PTEN IGF1 ESR2 ESR1 CTNNB1
256 wilms tumor 1 10.3 TP53 PGR MED12 IGF1 ESR1 EPPIN
257 disorders of sexual development 10.3 IGF1 GNRH1 ESR2 ESR1 EPPIN CYP19A1
258 adenomyoma 10.3 PGR MME MED12 GNRH1 ESR1 CTNNB1
259 uterine carcinosarcoma 10.3 TP53 PTEN PGR MME ESR2 ESR1
260 myeloma, multiple 10.3 TP53 PTEN MME IGF1 ESR1 CTNNB1
261 endometrial adenocarcinoma 10.3 TP53 PTEN PGR IGF1 ESR2 ESR1
262 breast disease 10.3 TP53 PGR MIR146A IGF1 ESR2 ESR1
263 endometrial stromal sarcoma 10.3 TP53 PGR MME ESR2 ESR1 CYP19A1
264 mixed cell type cancer 10.3 TP53 PTEN PGR MME ESR1 CTNNB1
265 suppression of tumorigenicity 12 10.3 TP53 PTEN IGF1 GNRH1 ESR2 ESR1
266 pancreatic adenocarcinoma 10.2 TP53 PTEN IGF1 ESR1 CTNNB1
267 cell type benign neoplasm 10.2 TSC2 TP53 PTEN IGF1 FH ESR1
268 lung cancer susceptibility 3 10.2 TSC2 TP53 PTEN ESR2 ESR1 CTNNB1
269 endometriosis 10.2 TP53 PTEN PGR HOXA10 GNRH1 ESR2
270 glioblastoma multiforme 10.2 TSC2 TP53 PTEN IGF1 ESR1 CTNNB1
271 leukemia, acute myeloid 10.2 TP53 PTEN MME MIR146A HOXA10 ESR1
272 cryptorchidism, unilateral or bilateral 10.2 IGF1 HOXA10 GNRH1 ESR2 ESR1 EPPIN
273 neuroblastoma 10.1 TSC2 TP53 PTEN IGF1 ESR1 CTNNB1
274 retinal cancer 10.1 TP53 PTEN CTNNB1
275 hypertension, essential 10.1 TP53 MME MIR146A IGF1 ESR2 ESR1
276 premature ovarian failure 1 10.1 PTEN MIR146A IGF1 GNRH1 ESR2 ESR1
277 adenomyosis 10.1 TP53 PGR MME HOXA10 GNRH1 ESR2
278 osteoporosis 10.1 TP53 PTEN PGR IGF1 GNRH1 ESR2
279 diabetes mellitus, noninsulin-dependent 10.1 TSC2 TP53 MIR146A IGF1 ESR2 ESR1
280 body mass index quantitative trait locus 11 10.1 TP53 MIR146A IGF1 ESR1 CYP19A1 CTNNB1
281 leiomyoma 10.0 TSC2 PGR MME MED12 HMGA2 GNRH1
282 autosomal genetic disease 10.0 TSC2 TP53 PTEN MIR146A IGF1 ESR2
283 colorectal adenoma 9.9 TP53 IGF1 CTNNB1
284 endometrial cancer 9.9 TP53 PTEN PGR MME IGF1 HOXA10
285 ovarian cancer 9.9 TP53 PTEN PGR MIR146A IGF1 HMGA2
286 ovarian disease 9.8 TP53 PTEN PGR MIR146A IGF1 GNRH1
287 prostate cancer 9.8 TP53 PTEN PGR MME MIR146A IGF1
288 myoma 9.8 TP53 PGR MME MED12 HPSE2 HOXA10
289 reproductive organ benign neoplasm 9.2 TSC2 TP53 PTEN PGR MME MED12

Graphical network of the top 20 diseases related to Uterine Benign Neoplasm:



Diseases related to Uterine Benign Neoplasm

Symptoms & Phenotypes for Uterine Benign Neoplasm

GenomeRNAi Phenotypes related to Uterine Benign Neoplasm according to GeneCards Suite gene sharing:

26 (showing 3, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased TP53 mRNA expression GR00389-S-5 9.26 TP53
2 Decreased TP53 mRNA expression GR00389-S-6 9.26 ESR2 HMGA2 TP53
3 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.92 ESR1 ESR2 FH PTEN

MGI Mouse Phenotypes related to Uterine Benign Neoplasm:

45 (showing 17, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.34 AMH CTNNB1 CYP19A1 ESR1 ESR2 FH
2 cellular MP:0005384 10.33 CTNNB1 CYP19A1 ESR1 ESR2 FH IGF1
3 cardiovascular system MP:0005385 10.3 CTNNB1 CYP19A1 ESR1 ESR2 HOXA10 IGF1
4 endocrine/exocrine gland MP:0005379 10.3 AMH CTNNB1 CYP19A1 ESR1 ESR2 GNRH1
5 growth/size/body region MP:0005378 10.29 CTNNB1 CYP19A1 ESR1 ESR2 GNRH1 HOXA10
6 integument MP:0010771 10.22 CTNNB1 CYP19A1 ESR1 ESR2 GNRH1 IGF1
7 digestive/alimentary MP:0005381 10.19 CTNNB1 CYP19A1 ESR1 ESR2 GNRH1 HOXA10
8 adipose tissue MP:0005375 10.11 CYP19A1 ESR1 ESR2 HOXA10 IGF1 PTEN
9 limbs/digits/tail MP:0005371 10.11 CTNNB1 ESR1 ESR2 HOXA10 IGF1 MED12
10 nervous system MP:0003631 10.1 CTNNB1 CYP19A1 ESR1 ESR2 GNRH1 HOXA10
11 liver/biliary system MP:0005370 10.09 CTNNB1 CYP19A1 ESR1 ESR2 GNRH1 MME
12 neoplasm MP:0002006 10.07 AMH CTNNB1 ESR1 ESR2 GNRH1 IGF1
13 muscle MP:0005369 10.01 CTNNB1 CYP19A1 ESR1 ESR2 IGF1 PGR
14 normal MP:0002873 10 CTNNB1 CYP19A1 ESR1 ESR2 GNRH1 IGF1
15 renal/urinary system MP:0005367 9.9 CTNNB1 CYP19A1 ESR1 ESR2 FH GNRH1
16 reproductive system MP:0005389 9.73 AMH CTNNB1 CYP19A1 ESR1 ESR2 GNRH1
17 skeleton MP:0005390 9.36 CTNNB1 CYP19A1 ESR1 ESR2 GNRH1 HOXA10

Drugs & Therapeutics for Uterine Benign Neoplasm

Interventional clinical trials:

(showing 1, show less)
# Name Status NCT ID Phase Drugs
1 Therapeutic Efficacy of High-intensity Focused Ultrasound in the Treatment of Uterine Fibroid Completed NCT02954744

Search NIH Clinical Center for Uterine Benign Neoplasm

Genetic Tests for Uterine Benign Neoplasm

Anatomical Context for Uterine Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Uterine Benign Neoplasm:

19
Uterus

MalaCards organs/tissues related to Uterine Benign Neoplasm:

40
Uterus

Publications for Uterine Benign Neoplasm

Variations for Uterine Benign Neoplasm

Expression for Uterine Benign Neoplasm

Search GEO for disease gene expression data for Uterine Benign Neoplasm.

Pathways for Uterine Benign Neoplasm

Pathways related to Uterine Benign Neoplasm according to GeneCards Suite gene sharing:

(showing 17, show less)
# Super pathways Score Top Affiliating Genes
1 12.64 TP53 PTEN IGF1 FH ESR2 ESR1
2
Show member pathways
12.53 TP53 PTEN PGR IGF1 ESR2 ESR1
3
Show member pathways
12.48 TSC2 TP53 PTEN IGF1 ESR2 ESR1
4
Show member pathways
12.23 TSC2 TP53 PTEN IGF1
5
Show member pathways
12.21 TSC2 TP53 PTEN IGF1
6
Show member pathways
12.17 TSC2 TP53 PTEN IGF1 CTNNB1
7 12.14 TP53 IGF1 HPSE2 ESR1 CTNNB1
8 12.11 TP53 IGF1 HOXA10 HMGA2
9 11.74 TSC2 TP53 MED12 ESR1 CTNNB1
10
Show member pathways
11.7 PGR ESR2 ESR1
11 11.66 TSC2 TP53 PTEN
12 11.6 TSC2 TP53 PTEN IGF1 CTNNB1
13 11.31 TSC2 TP53 ESR1
14 11.29 TSC2 TP53 PTEN ESR1 CYP19A1 CTNNB1
15 11.24 TP53 PTEN ESR1
16 11.16 PGR ESR2 CYP19A1
17 9.73 ESR2 ESR1 CYP19A1

GO Terms for Uterine Benign Neoplasm

Biological processes related to Uterine Benign Neoplasm according to GeneCards Suite gene sharing:

(showing 24, show less)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 10.01 TP53 PGR MED12 IGF1 HOXA10 HMGA2
2 negative regulation of cell proliferation GO:0008285 9.97 TSC2 TP53 PTEN GNRH1 CTNNB1
3 negative regulation of apoptotic process GO:0043066 9.95 TP53 PTEN IGF1 HMGA2 GNRH1 CTNNB1
4 cell-cell signaling GO:0007267 9.91 PGR GNRH1 ESR2 AMH
5 positive regulation of apoptotic process GO:0043065 9.91 TP53 PTEN MIR146A HMGA2 CTNNB1
6 positive regulation of transcription, DNA-templated GO:0045893 9.87 TP53 MED12 IGF1 HMGA2 ESR2 ESR1
7 aging GO:0007568 9.84 PTEN MME GNRH1 AMH
8 canonical Wnt signaling pathway GO:0060070 9.77 PTEN MED12 CTNNB1
9 heart development GO:0007507 9.77 TSC2 TP53 PTEN MED12 CTNNB1
10 positive regulation of DNA-binding transcription factor activity GO:0051091 9.76 PTEN ESR2 ESR1 CTNNB1
11 response to estradiol GO:0032355 9.73 PTEN ESR1 CYP19A1 CTNNB1
12 negative regulation of protein kinase B signaling GO:0051898 9.72 TSC2 PTEN MIR146A
13 protein kinase B signaling GO:0043491 9.67 TSC2 PTEN IGF1
14 replicative senescence GO:0090399 9.62 TP53 MME
15 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899 9.61 TP53 ESR1
16 negative regulation of production of miRNAs involved in gene silencing by miRNA GO:1903799 9.6 TP53 ESR1
17 positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9.58 MIR146A CTNNB1
18 prostate gland growth GO:0060736 9.57 PTEN CYP19A1
19 regulation of toll-like receptor signaling pathway GO:0034121 9.56 MIR146A ESR1
20 transcription initiation from RNA polymerase II promoter GO:0006367 9.55 PTEN PGR MED12 ESR2 ESR1
21 negative regulation of mitophagy GO:1901525 9.52 TSC2 TP53
22 uterus development GO:0060065 9.43 HOXA10 ESR1 CYP19A1
23 negative regulation of gene expression GO:0010629 9.43 TP53 PGR MIR146A IGF1 ESR1 CTNNB1
24 positive regulation of gene expression GO:0010628 9.17 TP53 PTEN MIR146A IGF1 HMGA2 CTNNB1

Molecular functions related to Uterine Benign Neoplasm according to GeneCards Suite gene sharing:

(showing 11, show less)
# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.88 TP53 PGR HOXA10 HMGA2 ESR1
2 transcription factor binding GO:0008134 9.83 TP53 MED12 HMGA2 ESR1 CTNNB1
3 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.7 TP53 PGR MED12 HOXA10 HMGA2 ESR2
4 beta-catenin binding GO:0008013 9.67 MED12 ESR1 CTNNB1
5 steroid hormone receptor activity GO:0003707 9.63 PGR ESR2 ESR1
6 nuclear receptor activity GO:0004879 9.54 PGR ESR2 ESR1
7 steroid binding GO:0005496 9.43 PGR ESR2 ESR1
8 enzyme binding GO:0019899 9.43 TP53 PTEN PGR ESR2 ESR1 CTNNB1
9 estrogen receptor activity GO:0030284 9.4 ESR2 ESR1
10 estrogen response element binding GO:0034056 9.32 ESR2 ESR1
11 repressing transcription factor binding GO:0070491 8.92 PGR ESR2 ESR1 CTNNB1

Sources for Uterine Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....