Uterine Body Mixed Cancer disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: UTR032 MIFTS: 32	Uterine Body Mixed Cancer Categories: Cancer diseases, Reproductive diseases
Genes Tissues Related diseases Pathways Expand all tables

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Aliases & Classifications for Uterine Body Mixed Cancer

MalaCards integrated aliases for Uterine Body Mixed Cancer:

Name: Uterine Body Mixed Cancer ¹² ¹⁵

Malignant Mixed Tumor, Not Otherwise Specified ⁷⁰

Malignant Mixed Tumor of Corpus Uteri ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4114

NCIt ⁵⁰ C6311

UMLS ⁷⁰ C1334628 C4054577

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Summaries for Uterine Body Mixed Cancer

Disease Ontology : ¹² A uterine corpus cancer that has material basis in more than one type of cell.

MalaCards based summary : Uterine Body Mixed Cancer, also known as malignant mixed tumor, not otherwise specified, is related to uterine carcinosarcoma and uterine corpus adenocarcinofibroma. An important gene associated with Uterine Body Mixed Cancer is U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1), and among its related pathways/superpathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Affiliated tissues include breast, lung and colon, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

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Related Diseases for Uterine Body Mixed Cancer

Diseases related to Uterine Body Mixed Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 295)

#	Related Disease	Score	Top Affiliating Genes
1	uterine carcinosarcoma	31.1	U2AF1 TP53 RACGAP1 PTEN PPP2R1A POLE
2	uterine corpus adenocarcinofibroma	11.2
3	thyroid hurthle cell adenoma	10.5	PTEN PIK3CA
4	gastric papillary adenocarcinoma	10.4	TP53 ERBB2
5	clear cell adenofibroma	10.4	PPP2R1A PIK3CA ARID1A
6	vulvar intraepithelial neoplasia	10.4	TP53 CTNNB1
7	hepatic flexure cancer	10.4	KRAS HRAS
8	apocrine adenosis of breast	10.4	TP53 ERBB2
9	parameningeal embryonal rhabdomyosarcoma	10.4	TP53 PIK3CA FBXW7
10	breast squamous cell carcinoma	10.4	TP53 ERBB2
11	trachea carcinoma in situ	10.4	KRAS HRAS
12	signet ring basal cell carcinoma	10.4	KRAS HRAS
13	cobblestone retinal degeneration	10.4	KRAS HRAS
14	myoepithelial carcinoma	10.4	TP53 PIK3CA HRAS
15	familial ovarian cancer	10.4	TP53 PTEN POLE
16	immature teratoma of ovary	10.4	KRAS HRAS
17	breast juvenile papillomatosis	10.4	PIK3CA ERBB2
18	spitz nevus	10.4	TP53 HRAS
19	hypertrophy of breast	10.4	TP53 PIK3CA ERBB2
20	ovarian clear cell adenocarcinoma	10.4	TP53 PIK3CA ARID1A
21	clear cell adenocarcinoma	10.4	TP53 PIK3CA ARID1A
22	lung oat cell carcinoma	10.4	TP53 PTEN PIK3CA
23	prostate squamous cell carcinoma	10.4	TP53 PIK3CA HRAS
24	extracutaneous mastocytoma	10.4	U2AF1 KIT
25	testicular gonadoblastoma	10.4	KIT CTNNB1
26	ovarian clear cell adenofibroma	10.4	PTEN PIK3CA KRAS
27	descending colon cancer	10.4	KRAS HRAS
28	gallbladder adenocarcinoma	10.4	TP53 PIK3CA ERBB2
29	ampulla of vater benign neoplasm	10.4	KRAS HRAS
30	parotid gland cancer	10.4	TP53 ERBB2
31	pancreatic signet ring cell adenocarcinoma	10.4	TP53 KRAS HRAS
32	ovarian mucinous neoplasm	10.4	U2AF1 KRAS HRAS
33	bone giant cell sarcoma	10.3	TP53 KRAS HRAS
34	periampullary adenoma	10.3	KRAS HRAS
35	embryonal rhabdomyosarcoma	10.3	TP53 KRAS HRAS
36	biliary tract benign neoplasm	10.3	TP53 KRAS HRAS
37	adenosquamous lung carcinoma	10.3	PIK3CA KRAS HRAS
38	hemimegalencephaly	10.3	PTEN PIK3CA CTNNB1
39	malignant exocrine pancreas neoplasm	10.3	TP53 KRAS HRAS
40	appendix disease	10.3	TP53 KRAS HRAS
41	papillary adenoma	10.3	TP53 KRAS HRAS
42	appendix cancer	10.3	TP53 KRAS HRAS
43	nasal cavity adenocarcinoma	10.3	TP53 KRAS HRAS
44	lobular neoplasia	10.3	TP53 ERBB2 CTNNB1
45	rectosigmoid cancer	10.3	POLE KRAS HRAS
46	oculoectodermal syndrome	10.3	PIK3CA KRAS HRAS
47	breast malignant phyllodes tumor	10.3	TP53 KIT ERBB2
48	liver benign neoplasm	10.3	TP53 HRAS CTNNB1
49	eccrine papillary adenoma	10.3	PIK3CA KRAS HRAS
50	acneiform dermatitis	10.3	KRAS HRAS

Graphical network of the top 20 diseases related to Uterine Body Mixed Cancer:

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Symptoms & Phenotypes for Uterine Body Mixed Cancer

GenomeRNAi Phenotypes related to Uterine Body Mixed Cancer according to GeneCards Suite gene sharing:

²⁶ (show all 40)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-1	10.04	POLE
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-120	10.04	KRAS
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-121	10.04	FBXW7
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-122	10.04	FBXW7
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-123	10.04	POLE
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-151	10.04	PTEN
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-152	10.04	KIT
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-157	10.04	KIT
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-16	10.04	PTEN ARID1B
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-161	10.04	ERBB2
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-168	10.04	ARID1A ERBB2 POLE PTEN
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-170	10.04	KIT
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-176	10.04	ARID1A
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-183	10.04	FBXW7
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-186	10.04	ARID1A
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-190	10.04	ARID1A
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-199	10.04	POLE
18	Increased shRNA abundance (Z-score > 2)	GR00366-A-207	10.04	ERBB2 POLE
19	Increased shRNA abundance (Z-score > 2)	GR00366-A-213	10.04	ARID1A
20	Increased shRNA abundance (Z-score > 2)	GR00366-A-214	10.04	PTEN
21	Increased shRNA abundance (Z-score > 2)	GR00366-A-22	10.04	KRAS
22	Increased shRNA abundance (Z-score > 2)	GR00366-A-30	10.04	KIT
23	Increased shRNA abundance (Z-score > 2)	GR00366-A-32	10.04	ERBB2 POLE
24	Increased shRNA abundance (Z-score > 2)	GR00366-A-42	10.04	PTEN
25	Increased shRNA abundance (Z-score > 2)	GR00366-A-43	10.04	ARID1A
26	Increased shRNA abundance (Z-score > 2)	GR00366-A-52	10.04	FBXW7
27	Increased shRNA abundance (Z-score > 2)	GR00366-A-60	10.04	ERBB2 PIK3CA
28	Increased shRNA abundance (Z-score > 2)	GR00366-A-61	10.04	KIT
29	Increased shRNA abundance (Z-score > 2)	GR00366-A-63	10.04	ERBB2 KRAS POLE PTEN
30	Increased shRNA abundance (Z-score > 2)	GR00366-A-66	10.04	PTEN
31	Increased shRNA abundance (Z-score > 2)	GR00366-A-72	10.04	ARID1B
32	Increased shRNA abundance (Z-score > 2)	GR00366-A-73	10.04	ARID1A
33	Increased shRNA abundance (Z-score > 2)	GR00366-A-85	10.04	ERBB2 POLE KIT
34	Increased shRNA abundance (Z-score > 2)	GR00366-A-87	10.04	ERBB2 POLE PTEN
35	Increased shRNA abundance (Z-score > 2)	GR00366-A-9	10.04	KIT
36	Increased shRNA abundance (Z-score > 2)	GR00366-A-91	10.04	POLE
37	Increased shRNA abundance (Z-score > 2)	GR00366-A-93	10.04	PTEN
38	Increased shRNA abundance (Z-score > 2)	GR00366-A-99	10.04	KIT
39	Decreased cell migration	GR00055-A-3	9.16	HRAS PIK3CA
40	Increased focal adhesion (FA) area, decreased number of small and round FAs, increased peripheral FA formation, increased cell spreading	GR00210-A	8.65	CTNNB1

MGI Mouse Phenotypes related to Uterine Body Mixed Cancer:

⁴⁶ (show all 14)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	10.3	ARID1A ARID1B CTNNB1 ERBB2 FAM131A FBXW7
2	cardiovascular system	MP:0005385	10.28	ARID1A ARID1B CTNNB1 ERBB2 FBXW7 HRAS
3	mortality/aging	MP:0010768	10.24	ARID1A ARID1B CTNNB1 ERBB2 FBXW7 HRAS
4	endocrine/exocrine gland	MP:0005379	10.22	ARID1A CTNNB1 ERBB2 FBXW7 HRAS KIT
5	immune system	MP:0005387	10.21	ARID1A ARID1B CTNNB1 FBXW7 KIT KRAS
6	embryo	MP:0005380	10.19	ARID1A CTNNB1 ERBB2 FBXW7 KIT KRAS
7	craniofacial	MP:0005382	10.18	ARID1A ARID1B CTNNB1 ERBB2 FBXW7 HRAS
8	integument	MP:0010771	10.18	ARID1B CTNNB1 ERBB2 FBXW7 HRAS KIT
9	digestive/alimentary	MP:0005381	10.16	CTNNB1 ERBB2 FBXW7 HRAS KIT KRAS
10	neoplasm	MP:0002006	10.07	ARID1A CTNNB1 ERBB2 FBXW7 HRAS KIT
11	muscle	MP:0005369	10.02	ARID1A ARID1B CTNNB1 ERBB2 HRAS KIT
12	no phenotypic analysis	MP:0003012	9.7	ARID1A CTNNB1 HRAS KIT KRAS PIK3CA
13	normal	MP:0002873	9.65	ARID1A CTNNB1 ERBB2 FBXW7 HRAS KIT
14	respiratory system	MP:0005388	9.28	CTNNB1 ERBB2 FBXW7 HRAS KIT KRAS

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Drugs & Therapeutics for Uterine Body Mixed Cancer

Search Clinical Trials , NIH Clinical Center for Uterine Body Mixed Cancer

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Genetic Tests for Uterine Body Mixed Cancer

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Anatomical Context for Uterine Body Mixed Cancer

MalaCards organs/tissues related to Uterine Body Mixed Cancer:

⁴⁰

Breast, Lung, Colon, Thyroid, Skin, Ovary, Myeloid

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Publications for Uterine Body Mixed Cancer

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Genes for Uterine Body Mixed Cancer

Genes related to Uterine Body Mixed Cancer (0 elite genes):

(show all 28)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	U2AF1	U2 Small Nuclear RNA Auxiliary Factor 1	Protein Coding	7.61	DISEASES inferred ¹⁵ ¹⁵
2	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	6.66	DISEASES inferred ¹⁵
3	POLE	DNA Polymerase Epsilon, Catalytic Subunit	Protein Coding	6.36	DISEASES inferred ¹⁵
4	TP53	Tumor Protein P53	Protein Coding	6.27	DISEASES inferred ¹⁵
5	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	6.24	DISEASES inferred ¹⁵
6	ARID1A	AT-Rich Interaction Domain 1A	Protein Coding	6.18	DISEASES inferred ¹⁵
7	FBXW7	F-Box And WD Repeat Domain Containing 7	Protein Coding	6.18	DISEASES inferred ¹⁵
8	SLC25A16	Solute Carrier Family 25 Member 16	Protein Coding	6.14	DISEASES inferred ¹⁵
9	PTEN	Phosphatase And Tensin Homolog	Protein Coding	6.01	DISEASES inferred ¹⁵
10	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	5.94	DISEASES inferred ¹⁵
11	RACGAP1	Rac GTPase Activating Protein 1	Protein Coding	5.75	DISEASES inferred ¹⁵
12	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	5.56	DISEASES inferred ¹⁵
13	CTNNB1	Catenin Beta 1	Protein Coding	5.48	DISEASES inferred ¹⁵
14	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	5.47	DISEASES inferred ¹⁵
15	C10orf126	Chromosome 10 Open Reading Frame 126	RNA Gene	5.45	DISEASES inferred ¹⁵
16	MLH1	MutL Homolog 1	Protein Coding	5.44	DISEASES inferred ¹⁵
17	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	5.35	DISEASES inferred ¹⁵
18	FAM131A	Family With Sequence Similarity 131 Member A	Protein Coding	5.33	DISEASES inferred ¹⁵
19	DPY19L4	Dpy-19 Like 4	Protein Coding	5.33	DISEASES inferred ¹⁵
20	ARID1B	AT-Rich Interaction Domain 1B	Protein Coding	5.33	DISEASES inferred ¹⁵
21	EGFR	Epidermal Growth Factor Receptor	Protein Coding	5.3	DISEASES inferred ¹⁵
22	ESR1	Estrogen Receptor 1	Protein Coding	5.28	DISEASES inferred ¹⁵
23	SRGAP3-AS2	SRGAP3 Antisense RNA 2	RNA Gene	5.27	DISEASES inferred ¹⁵
24	TVP23C	Trans-Golgi Network Vesicle Protein 23 Homolog C	Protein Coding	5.23	DISEASES inferred ¹⁵
25	SNAI2	Snail Family Transcriptional Repressor 2	Protein Coding	5.23	DISEASES inferred ¹⁵
26	ZNF217	Zinc Finger Protein 217	Protein Coding	5.22	DISEASES inferred ¹⁵
27	CCDC168	Coiled-Coil Domain Containing 168	Protein Coding	5.19	DISEASES inferred ¹⁵
28	MSH6	MutS Homolog 6	Protein Coding	5.18	DISEASES inferred ¹⁵

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Variations for Uterine Body Mixed Cancer

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Expression for Uterine Body Mixed Cancer

Search GEO for disease gene expression data for Uterine Body Mixed Cancer.

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Pathways for Uterine Body Mixed Cancer

Pathways related to Uterine Body Mixed Cancer according to GeneCards Suite gene sharing:

(show top 50) (show all 72)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁵ Show member pathways Immune System ⁶⁵ Neutrophil degranulation ⁶⁵	14.08	TP53 RACGAP1 PTEN PPP2R1A PIK3CA KRAS
2	Class I MHC mediated antigen processing and presentation ⁶⁵ Show member pathways Adaptive Immune System ⁶⁵ Antigen processing- Ubiquitination and Proteasome degradation ⁶⁵	13.45	TP53 RACGAP1 PTEN PPP2R1A PIK3CA KRAS
3	Cytokine Signaling in Immune system ⁶⁵ Show member pathways Signaling by Interleukins ⁶⁵	13.39	TP53 PPP2R1A PIK3CA KRAS KIT HRAS
4	PI3K/AKT activation ⁶⁵ Show member pathways Constitutive Signaling by Aberrant PI3K in Cancer ⁶⁵ GAB1 signalosome ⁶⁵ Negative regulation of the PI3K/AKT network ⁶⁵ PI3K/AKT Signaling in Cancer ⁶⁵ PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling ⁶⁵ PIP3 activates AKT signaling ⁶⁵ Role of LAT2/NTAL/LAB on calcium mobilization ⁶⁵	13.15	TP53 PTEN PPP2R1A PIK3CA KIT ERBB2
5	Focal Adhesion ³⁶ ¹ Show member pathways HGF Pathway ⁶³ Integrin-mediated Cell Adhesion ¹	12.93	PTEN PIK3CA KRAS HRAS ERBB2 CTNNB1
6	PI3K-Akt signaling pathway ³⁶ Show member pathways Human papillomavirus infection ³⁶	12.92	TP53 PTEN PPP2R1A PIK3CA KRAS KIT
7	MAPK signaling pathway ³⁶ ¹	12.8	TP53 KRAS KIT HRAS ERBB2
8	Ras signaling pathway ³⁶ Show member pathways Rap1 signaling pathway ³⁶	12.76	PIK3CA KRAS KIT HRAS CTNNB1
9	Endometrial cancer ³⁶ Show member pathways Binding of TCF/LEF-CTNNB1 to target gene promoters ⁶⁵ Chronic myeloid leukemia ³⁶ Colorectal cancer ³⁶ Pancreatic cancer ³⁶ Prostate cancer ³⁶ Signal transduction PTEN pathway ²³ Thyroid cancer ³⁶	12.75	TP53 PTEN PIK3CA MLH1 KRAS HRAS
10	Glioma ³⁶ Show member pathways Endocrine resistance ³⁶ Melanoma ³⁶ Non-small cell lung cancer ³⁶ Signaling Pathways in Glioblastoma ¹	12.73	TP53 PTEN PIK3CA KRAS HRAS ERBB2
11	Development HGF signaling pathway ²³ Show member pathways Apoptosis and survival Anti-apoptotic action of membrane-bound ESR1 ²³ Apoptosis and survival NGF signaling pathway ²³ Apoptosis and survival Role of CDK5 in neuronal death and survival ²³ Development Neurotrophin family signaling ²³ MET activates STAT3 ⁶⁵ Neurotrophin signaling pathway ³⁶ Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) ¹ Signaling of Hepatocyte Growth Factor Receptor ¹	12.71	TP53 PTEN PIK3CA KRAS HRAS ERBB2
12	Pathways in cancer ³⁶	12.7	TP53 PTEN PIK3CA MLH1 KRAS KIT
13	Downstream signaling events of B Cell Receptor (BCR) ⁶⁵ Show member pathways Activation of RAS in B cells ⁶⁵ Signaling by the B Cell Receptor (BCR) ⁶⁵	12.65	TP53 PTEN PPP2R1A PIK3CA KRAS KIT
14	Immune response IL-23 signaling pathway ²³ Show member pathways Angiopoietin receptor Tie2-mediated signaling ¹ Angiopoietin-TIE2 Signaling ⁶³ Development Angiopoietin - Tie2 signaling ²³ Development PDGF signaling via STATs and NF-kB ²³ IL23-mediated signaling events ¹ Immune response IL-10 signaling pathway ²³ Rac1/Pak1/p38/MMP-2 pathway ¹	12.64	TP53 PIK3CA KRAS HRAS ERBB2 CTNNB1
15	MicroRNAs in cancer ³⁶	12.57	TP53 PTEN PIK3CA KRAS HRAS ERBB2
16	mTOR signaling pathway (KEGG) ³⁶ Show member pathways mTOR Signaling Pathway ⁶⁴	12.54	TP53 PTEN PIK3CA KRAS HRAS ERBB2
17	ErbB signaling pathway ³⁶ ¹ Show member pathways EGFR Inhibitor Pathway, Pharmacodynamics ⁶⁰ EGFR tyrosine kinase inhibitor resistance ³⁶ TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer ¹	12.53	TP53 PTEN PIK3CA KRAS HRAS ERBB2
18	Prolactin Signaling Pathway ¹ ³⁶ Show member pathways Development Prolactin receptor signaling ²³ Leptin signaling pathway ¹	12.52	PTEN PIK3CA KRAS HRAS ERBB2
19	Apoptosis Pathway ⁶⁹ Show member pathways Akt Pathway ⁶⁹ NF-kappaB Pathway ⁶⁹	12.47	TP53 PIK3CA KRAS HRAS ERBB2 CTNNB1
20	B cell receptor signaling pathway (KEGG) ³⁶ Show member pathways B Cell Receptor Signaling Pathway ¹ BCR signaling pathway ¹	12.44	PTEN PIK3CA KRAS HRAS
21	Phospholipase D signaling pathway ³⁶ Show member pathways Choline metabolism in cancer ³⁶	12.43	PIK3CA KRAS KIT HRAS
22	Development VEGF signaling via VEGFR2 - generic cascades ²³ Show member pathways Development VEGF signaling and activation ²³ VEGF - VEGF R2 Signaling Pathways ⁶⁴	12.43	PIK3CA KRAS HRAS CTNNB1
23	Development IGF-1 receptor signaling ²³ Show member pathways IL-4 Signaling Pathway ¹ Immune response IL-4 signaling pathway ²³ Signal transduction AKT signaling ²³	12.42	TP53 PTEN PIK3CA HRAS
24	G-protein signaling RAC1 in cellular process ²³ Show member pathways CDC42 signaling events ¹ Cytoskeleton remodeling CDC42 in cellular processes ²³ RAC1 signaling pathway ¹	12.42	RACGAP1 PIK3CA KRAS KIT HRAS ERBB2
25	VEGF Signaling ⁶⁶ Show member pathways EGFR Signaling Pathway ⁶⁶ VEGF Signaling Pathway ⁶⁰	12.41	TP53 PTEN KRAS HRAS CTNNB1
26	Human T-cell leukemia virus 1 infection ³⁶	12.4	TP53 PTEN PIK3CA KRAS HRAS
27	Development EGFR signaling pathway ²³ Show member pathways Development ERBB-family signaling ²³ EGF Pathway ⁶³ ErbB receptor signaling network ¹	12.37	PIK3CA KRAS HRAS ERBB2 CTNNB1
28	Signaling by ERBB2 ⁶⁵ Show member pathways Downregulation of ERBB2 signaling ⁶⁵ Downregulation of ERBB2-ERBB3 signaling ⁶⁵ ERBB2 Activates PTK6 Signaling ⁶⁵ ERBB2 Regulates Cell Motility ⁶⁵ GRB2 events in ERBB2 signaling ⁶⁵ GRB7 events in ERBB2 signaling ⁶⁵ PI3K events in ERBB2 signaling ⁶⁵ PI3K events in ERBB4 signaling ⁶⁵ PLCG1 events in ERBB2 signaling ⁶⁵ SHC1 events in ERBB2 signaling ⁶⁵ SHC1 events in ERBB4 signaling ⁶⁵	12.35	PIK3CA KRAS HRAS ERBB2
29	Viral carcinogenesis ³⁶	12.33	TP53 PIK3CA KRAS HRAS
30	Translation Non-genomic (rapid) action of Androgen Receptor ²³ Show member pathways Basal cell carcinoma ³⁶ Transcription Androgen Receptor nuclear signaling ²³	12.32	TP53 PTEN PIK3CA HRAS ERBB2 CTNNB1
31	Signaling by FGFR2 ⁶⁵ Show member pathways FGFR2 ligand binding and activation ⁶⁵ FGFR2b ligand binding and activation ⁶⁵ Signaling by FGFR ⁶⁵	12.3	PPP2R1A PIK3CA KRAS HRAS
32	MAPK Signaling: Mitogen Stimulation Pathway ⁶⁴ Show member pathways Akt Signaling Pathway ⁶⁴	12.28	TP53 PTEN PIK3CA KRAS HRAS ERBB2
33	Proteoglycans in cancer ³⁶	12.27	TP53 PIK3CA KRAS HRAS ERBB2 CTNNB1
34	Wnt Signaling Pathway and Pluripotency ¹ Show member pathways Wnt Signaling Pathway ¹	12.26	TP53 RACGAP1 PPP2R1A CTNNB1
35	Colorectal Cancer Metastasis ⁶³	12.22	TP53 MLH1 KRAS CTNNB1
36	EGF/EGFR Signaling Pathway ¹	12.22	PTEN KRAS HRAS ERBB2
37	Cellular senescence (KEGG) ³⁶	12.22	TP53 PTEN PIK3CA KRAS HRAS
38	Kit receptor signaling pathway ¹ Show member pathways IL-3 Signaling Pathway ¹ Signaling events mediated by Stem cell factor receptor (c-Kit) ¹	12.21	PTEN PIK3CA KIT HRAS
39	mTOR Pathway ⁶⁹ Show member pathways Insulin Pathway ⁶⁹ TGF-beta Pathway ⁶⁹	12.2	TP53 PIK3CA KRAS HRAS
40	Development EGFR signaling via small GTPases ²³ Show member pathways Development EGFR signaling via PIP3 ²³ Development PDGF signaling via MAPK cascades ²³ PDGF Pathway ¹	12.19	PTEN PIK3CA KRAS HRAS ERBB2
41	Integrated Breast Cancer Pathway ¹	12.18	TP53 PTEN KRAS CTNNB1
42	Longevity regulating pathway ³⁶ Show member pathways Longevity regulating pathway - multiple species ³⁶	12.17	TP53 PIK3CA KRAS HRAS
43	Signaling pathways regulating pluripotency of stem cells ³⁶	12.14	PIK3CA KRAS HRAS CTNNB1
44	FoxO signaling pathway ³⁶ Show member pathways PLK2 and PLK4 events ¹ Polo-like kinase signaling events in the cell cycle ¹	12.12	PTEN PIK3CA KRAS HRAS
45	Autophagy - animal ³⁶	12.11	PTEN PIK3CA KRAS HRAS
46	Thyroid hormone signaling pathway ³⁶	12.04	TP53 PIK3CA KRAS HRAS CTNNB1
47	Gastric cancer ³⁶ Show member pathways Breast cancer ³⁶ Hepatocellular carcinoma ³⁶	12.03	TP53 PTEN PIK3CA MLH1 KRAS KIT
48	Signaling by ERBB4 ⁶⁵ Show member pathways Downregulation of ERBB4 signaling ⁶⁵ ErbB4 signaling events ¹ Nuclear signaling by ERBB4 ⁶⁵	12	PIK3CA KRAS HRAS ERBB2
49	Reelin Pathway (Cajal-Retzius cells) ⁶³	11.99	RACGAP1 PPP2R1A HRAS CTNNB1
50	Glioblastoma Multiforme ⁶³	11.99	TP53 PTEN KRAS HRAS CTNNB1

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GO Terms for Uterine Body Mixed Cancer

Cellular components related to Uterine Body Mixed Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	nucleoplasm	GO:0005654	9.7	U2AF1 TP53 RACGAP1 PTEN POLE MLH1
2	brahma complex	GO:0035060	8.62	ARID1B ARID1A

Biological processes related to Uterine Body Mixed Cancer according to GeneCards Suite gene sharing:

(show all 12)

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of cell proliferation	GO:0008284	9.8	PTEN KRAS KIT HRAS ERBB2 CTNNB1
2	heart development	GO:0007507	9.78	TP53 PTEN ERBB2 CTNNB1
3	liver development	GO:0001889	9.69	PIK3CA KRAS HRAS
4	Ras protein signal transduction	GO:0007265	9.63	TP53 KRAS HRAS
5	embryonic organ development	GO:0048568	9.58	TP53 POLE CTNNB1
6	positive regulation of MAPK cascade	GO:0043410	9.56	KIT HRAS ERBB2 CTNNB1
7	phosphatidylinositol 3-kinase signaling	GO:0014065	9.54	PTEN PIK3CA ERBB2
8	chromatin-mediated maintenance of transcription	GO:0048096	9.49	ARID1B ARID1A
9	response to isolation stress	GO:0035900	9.43	KRAS HRAS
10	vasculature development	GO:0001944	9.33	PIK3CA FBXW7 CTNNB1
11	positive regulation of MAP kinase activity	GO:0043406	9.26	KRAS KIT HRAS ERBB2
12	positive regulation of gene expression	GO:0010628	9.17	TP53 PTEN KRAS KIT HRAS ERBB2

Sources

Sources for Uterine Body Mixed Cancer

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 20-May-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia