MCID: UTR056
MIFTS: 20

Uterine Corpus Endometrial Carcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Uterine Corpus Endometrial Carcinoma

MalaCards integrated aliases for Uterine Corpus Endometrial Carcinoma:

Name: Uterine Corpus Endometrial Carcinoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050939

Summaries for Uterine Corpus Endometrial Carcinoma

Disease Ontology : 12 A uterine corpus cancer that is derives from the inner lining of the uterus.

MalaCards based summary : Uterine Corpus Endometrial Carcinoma is related to endometrial cancer and hypoxia. An important gene associated with Uterine Corpus Endometrial Carcinoma is TCF21 (Transcription Factor 21), and among its related pathways/superpathways are Aurora B signaling and Gastric Cancer Network 1. Affiliated tissues include uterus, and related phenotypes are G0/1 arrest and Inhibition of centrosomal clustering

Related Diseases for Uterine Corpus Endometrial Carcinoma

Diseases related to Uterine Corpus Endometrial Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 endometrial cancer 10.1
2 hypoxia 10.1

Symptoms & Phenotypes for Uterine Corpus Endometrial Carcinoma

GenomeRNAi Phenotypes related to Uterine Corpus Endometrial Carcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 G0/1 arrest GR00098-A-2 9.43 CDCA8 MELK TPX2
2 Inhibition of centrosomal clustering GR00222-A-2 9.16 CDCA8 TPX2
3 Mitotic spindle defects GR00099-A 8.96 CDCA8 TPX2
4 Multipolar spindles GR00222-A-1 8.62 CDCA8 TPX2

Drugs & Therapeutics for Uterine Corpus Endometrial Carcinoma

Search Clinical Trials , NIH Clinical Center for Uterine Corpus Endometrial Carcinoma

Genetic Tests for Uterine Corpus Endometrial Carcinoma

Anatomical Context for Uterine Corpus Endometrial Carcinoma

MalaCards organs/tissues related to Uterine Corpus Endometrial Carcinoma:

41
Uterus

Publications for Uterine Corpus Endometrial Carcinoma

Articles related to Uterine Corpus Endometrial Carcinoma:

# Title Authors Year
1
LYL1 gene amplification predicts poor survival of patients with uterine corpus endometrial carcinoma: analysis of the Cancer genome atlas data. ( 29716549 )
2018
2
Bioinformatics analysis of RNA sequencing data reveals multiple key genes in uterine corpus endometrial carcinoma. ( 29387216 )
2018
3
A six-microRNA signature predicts survival of patients with uterine corpus endometrial carcinoma. ( 29567372 )
2018
4
A Novel Target of p53, TCF21, Can Respond to Hypoxia by MAPK Pathway Inactivation in Uterine Corpus Endometrial Carcinoma. ( 29608330 )
2018
5
TRB-J1 usage, in combination with the HLA-A*01:01 allele, represents an apparent survival advantage for uterine corpus endometrial carcinoma: Comparisons with microscopic assessments of lymphocyte infiltrates. ( 30474304 )
2018
6
Cancer-Related Triplets of mRNA-lncRNA-miRNA Revealed by Integrative Network in Uterine Corpus Endometrial Carcinoma. ( 28280730 )
2017

Variations for Uterine Corpus Endometrial Carcinoma

Expression for Uterine Corpus Endometrial Carcinoma

Search GEO for disease gene expression data for Uterine Corpus Endometrial Carcinoma.

Pathways for Uterine Corpus Endometrial Carcinoma

Pathways related to Uterine Corpus Endometrial Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.61 CDCA8 NCAPH
2 10.1 KIF15 TPX2

GO Terms for Uterine Corpus Endometrial Carcinoma

Cellular components related to Uterine Corpus Endometrial Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intercellular bridge GO:0045171 8.96 CDCA8 TPX2
2 spindle GO:0005819 8.8 CDCA8 KIF15 TPX2

Biological processes related to Uterine Corpus Endometrial Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell division GO:0051301 9.33 CDCA8 NCAPH TPX2
2 mitotic cell cycle GO:0000278 9.26 KIF15 TPX2
3 cell proliferation GO:0008283 9.13 KIF15 MELK TPX2
4 cell cycle GO:0007049 8.92 CDCA8 MELK NCAPH TPX2

Sources for Uterine Corpus Endometrial Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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