MCID: UTR009
MIFTS: 23

Uterus Carcinoma in Situ

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Uterus Carcinoma in Situ

MalaCards integrated aliases for Uterus Carcinoma in Situ:

Name: Uterus Carcinoma in Situ 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:9108
ICD9CM 34 233.2
SNOMED-CT 67 189342001
UMLS 70 C0154086

Summaries for Uterus Carcinoma in Situ

Disease Ontology : 12 An in situ carcinoma that is located in the uterus.

MalaCards based summary : Uterus Carcinoma in Situ is related to cervix uteri carcinoma in situ and early invasive cervical adenocarcinoma. An important gene associated with Uterus Carcinoma in Situ is MIR548B (MicroRNA 548b), and among its related pathways/superpathways are Glioblastoma Multiforme and Senescence and Autophagy in Cancer. Affiliated tissues include uterus.

Related Diseases for Uterus Carcinoma in Situ

Diseases related to Uterus Carcinoma in Situ via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 107)
# Related Disease Score Top Affiliating Genes
1 cervix uteri carcinoma in situ 27.4 TP53 SERPIND1 RUBCNL RB1 PTPRN MIR654
2 early invasive cervical adenocarcinoma 10.4 INSM1 CDKN2A
3 papillary squamous carcinoma 10.3 INSM1 CDKN2A
4 vulvar intraepithelial neoplasia 10.3 TP53 CDKN2A
5 esophagus verrucous carcinoma 10.3 TP53 CDKN2A
6 ovarian seromucinous carcinoma 10.3 TP53 CDKN2A
7 spitz nevus 10.3 TP53 CDKN2A
8 focal epithelial hyperplasia 10.3 GP6 GP5
9 bizarre leiomyoma 10.3 TP53 CDKN2A
10 basosquamous carcinoma 10.3 TP53 KRT17
11 adult malignant schwannoma 10.3 TP53 CDKN2A
12 comedo carcinoma 10.3 TP53 LCOR GP5
13 supraglottis cancer 10.3 TP53 CDKN2A
14 large cell acanthoma 10.3 TP53 KRT17
15 localized osteosarcoma 10.3 TP53 CDKN2A
16 malignant exocrine pancreas neoplasm 10.3 TP53 CDKN2A
17 thyroid lymphoma 10.2 TP53 CDKN2A
18 squamous cell papilloma 10.2 TP53 GP5 CDKN2A
19 penile benign neoplasm 10.2 TP53 GP5 CDKN2A
20 bladder clear cell adenocarcinoma 10.2 TP53 CDKN2A
21 vulva squamous cell carcinoma 10.2 TP53 GP5 CDKN2A
22 vulvar disease 10.2 TP53 GP5 CDKN2A
23 tonsil cancer 10.2 TP53 MIR338 CDKN2A
24 cervical adenosarcoma 10.2 TP53 GP6 GP5
25 inverted follicular keratosis 10.2 KRT17 GP6 GP5
26 penis squamous cell carcinoma 10.2 TP53 GP6 GP5
27 endocervical carcinoma 10.2 TP53 INSM1 CDKN2A
28 endocervical adenocarcinoma 10.2 TP53 INSM1 CDKN2A
29 soft palate cancer 10.2 GP6 CDKN2A
30 keratosis 10.2 TP53 KRT17 CDKN2A
31 urinary bladder inverted papilloma 10.2 RB1 CDKN2A
32 vulva cancer 10.2 TP53 GP5 CDKN2A
33 herpangina 10.2 TP53 GP6 GP5
34 clear cell basal cell carcinoma 10.2 TP53 KRT17
35 borst-jadassohn intraepidermal carcinoma 10.2 TP53 KRT17 CDKN2A
36 acanthoma 10.2 TP53 KRT17 CDKN2A
37 vulvar dystrophy 10.2 TP53 KRT17 CDKN2A
38 vulvar adenocarcinoma 10.2 TP53 RB1
39 keratinizing squamous cell carcinoma 10.2 TP53 CDKN2A
40 peritoneal serous adenocarcinoma 10.2 TP53 KRT17
41 basaloid squamous cell carcinoma 10.2 TP53 KRT17 CDKN2A
42 small cell carcinoma 10.2 TP53 INSM1 CDKN2A
43 keratosis, seborrheic 10.2 TP53 KRT17 CDKN2A
44 epidermodysplasia verruciformis 1 10.2 TP53 GP6 GP5
45 male reproductive organ benign neoplasm 10.2 TP53 CDKN2A
46 actinic keratosis 10.2 TP53 KRT17 CDKN2A
47 cervical squamous cell carcinoma 10.2 TP53 KRT17 CDKN2A
48 human papillomavirus infectious disease 10.2 TP53 FHIT CDKN2A
49 gallbladder adenoma 10.2 RB1 CDKN2A
50 megaesophagus 10.1 TP53 FHIT CDKN2A

Graphical network of the top 20 diseases related to Uterus Carcinoma in Situ:



Diseases related to Uterus Carcinoma in Situ

Symptoms & Phenotypes for Uterus Carcinoma in Situ

Drugs & Therapeutics for Uterus Carcinoma in Situ

Search Clinical Trials , NIH Clinical Center for Uterus Carcinoma in Situ

Genetic Tests for Uterus Carcinoma in Situ

Anatomical Context for Uterus Carcinoma in Situ

The Foundational Model of Anatomy Ontology organs/tissues related to Uterus Carcinoma in Situ:

19
Uterus

MalaCards organs/tissues related to Uterus Carcinoma in Situ:

40
Uterus

Publications for Uterus Carcinoma in Situ

Articles related to Uterus Carcinoma in Situ:

# Title Authors PMID Year
1
[A resected case of triple cancer in the uterus, lung and thyroid]. 61
2681446 1989

Variations for Uterus Carcinoma in Situ

Expression for Uterus Carcinoma in Situ

Search GEO for disease gene expression data for Uterus Carcinoma in Situ.

Pathways for Uterus Carcinoma in Situ

Pathways related to Uterus Carcinoma in Situ according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.63 TP53 RB1 CDKN2A
2 11.57 TP53 RB1 CDKN2A
3 11.46 TP53 RB1 FHIT
4 11.2 TP53 RB1 CDKN2A
5 10.84 TP53 RB1 CDKN2A
6 10.37 GP6 GP5
7 10.14 TP53 RB1 CDKN2A

GO Terms for Uterus Carcinoma in Situ

Biological processes related to Uterus Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras protein signal transduction GO:0007265 9.43 TP53 RB1 CDKN2A
2 replicative senescence GO:0090399 9.37 TP53 CDKN2A
3 hemostasis GO:0007599 9.33 SERPIND1 GP6 GP5
4 negative regulation of CD4-positive, alpha-beta T cell proliferation GO:2000562 9.32 LGALS7B LGALS7
5 apoptotic process GO:0006915 9.17 TP53 RB1 MAL LGALS7B LGALS7 FHIT
6 positive regulation of cell cycle arrest GO:0071158 9.13 TP53 INSM1 CDKN2A

Molecular functions related to Uterus Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 histone deacetylase binding GO:0042826 9.43 TP53 LCOR INSM1
2 MDM2/MDM4 family protein binding GO:0097371 9.16 TP53 CDKN2A
3 galactoside binding GO:0016936 8.96 LGALS7B LGALS7
4 disordered domain specific binding GO:0097718 8.8 TP53 RB1 CDKN2A

Sources for Uterus Carcinoma in Situ

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....