MCID: UTR009
MIFTS: 23

Uterus Carcinoma in Situ

Categories: Cancer diseases, Reproductive diseases
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Aliases & Classifications for Uterus Carcinoma in Situ

MalaCards integrated aliases for Uterus Carcinoma in Situ:

Name: Uterus Carcinoma in Situ 11 14

Classifications:



External Ids:

Disease Ontology 11 DOID:9108
ICD9CM 34 233.2
SNOMED-CT 68 189342001
UMLS 71 C0154086

Summaries for Uterus Carcinoma in Situ

Disease Ontology: 11 An in situ carcinoma that is located in the uterus.

MalaCards based summary: Uterus Carcinoma in Situ is related to cervix uteri carcinoma in situ and early invasive cervical adenocarcinoma. An important gene associated with Uterus Carcinoma in Situ is LCOR (Ligand Dependent Nuclear Receptor Corepressor), and among its related pathways/superpathways are TP53 network and Hypoxic and oxygen homeostasis regulation of HIF-1-alpha. Affiliated tissues include uterus, thyroid and lung, and related phenotypes are homeostasis/metabolism and integument

Related Diseases for Uterus Carcinoma in Situ

Diseases related to Uterus Carcinoma in Situ via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 104)
# Related Disease Score Top Affiliating Genes
1 cervix uteri carcinoma in situ 28.2 ZNF582 TP53 TMEM115 SERPIND1 RUBCNL PTPRN
2 early invasive cervical adenocarcinoma 10.3 INSM1 CDKN2A
3 cervical adenoid basal carcinoma 10.3 MAPK8IP1 KRT17
4 b-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) 10.3 TP53 CDKN2A
5 cervical carcinosarcoma 10.3 MAPK8IP1 GP5
6 endometrial squamous cell carcinoma 10.3 TP53 CDKN2A
7 esophagus verrucous carcinoma 10.3 TP53 CDKN2A
8 cervical mucinous adenocarcinoma 10.3 MAPK8IP1 CDKN2A
9 anus benign neoplasm 10.3 LCOR CDKN2A
10 bizarre leiomyoma 10.3 TP53 CDKN2A
11 cervix endometriosis 10.3 MAPK8IP1 CDKN2A
12 larynx squamous papilloma 10.3 TP53 CDKN2A
13 bladder clear cell adenocarcinoma 10.3 TP53 CDKN2A
14 atypical neurofibroma 10.3 TP53 CDKN2A
15 comedo carcinoma 10.3 TP53 LCOR GP5
16 lip cancer 10.3 TP53 CDKN2A
17 middle ear squamous cell carcinoma 10.3 GP6 GP5 CDKN2A
18 penis basal cell carcinoma 10.3 GP6 GP5 CDKN2A
19 inverted follicular keratosis 10.3 KRT17 GP6 GP5
20 male urethral cancer 10.3 TP53 CDKN2A
21 lymphoepithelioma-like carcinoma 10.3 TP53 CDKN2A
22 microinvasive cervical squamous cell carcinoma 10.3 PTPRN INSM1
23 squamous cell papilloma 10.3 TP53 GP5 CDKN2A
24 cervical clear cell adenocarcinoma 10.2 MAPK8IP1 GP5 CDKN2A
25 penile benign neoplasm 10.2 TP53 GP5 CDKN2A
26 papillary squamous carcinoma 10.2 MAPK8IP1 INSM1 CDKN2A
27 keratosis 10.2 TP53 KRT17 CDKN2A
28 large cell acanthoma 10.2 TP53 KRT17
29 male reproductive organ benign neoplasm 10.2 TP53 GP5 CDKN2A
30 clear cell basal cell carcinoma 10.2 TP53 KRT17
31 phimosis 10.2 TP53 GP5 CDKN2A
32 verrucous carcinoma 10.2 TP53 GP5 CDKN2A
33 vulvar disease 10.2 TP53 GP5 CDKN2A
34 soft palate cancer 10.2 GP6 CDKN2A
35 focal epithelial hyperplasia 10.2 TP53 GP6 GP5
36 ovarian seromucinous carcinoma 10.2 PAX1 CDKN2A
37 keratosis, seborrheic 10.2 TP53 KRT17 CDKN2A
38 synchronous bilateral breast carcinoma 10.2 TP53 KRT17
39 keratinizing squamous cell carcinoma 10.2 TP53 CDKN2A
40 ampulla of vater cancer 10.2 TP53 KRT17 CDKN2A
41 ductal carcinoma in situ 10.2 TP53 KRT17 CDKN2A
42 cervical intraepithelial neoplasia 10.2 KRT17 FHIT CDKN2A
43 suppressor of tumorigenicity 3 10.2 TP53 FHIT CDKN2A
44 paranasal sinus cancer 10.2 TP53 CDKN2A
45 small cell cancer of the lung 10.2 TP53 INSM1 CDKN2A
46 bilateral breast cancer 10.2 TP53 FHIT CDKN2A
47 muir-torre syndrome 10.2 TP53 FHIT CDKN2A
48 lung benign neoplasm 10.2 TP53 FHIT CDKN2A
49 fallopian tube endometrioid adenocarcinoma 10.2 PTPRN INSM1 CDKN2A
50 hemometra 10.2 PTPRN MAPK8IP1 INSM1

Graphical network of the top 20 diseases related to Uterus Carcinoma in Situ:



Diseases related to Uterus Carcinoma in Situ

Symptoms & Phenotypes for Uterus Carcinoma in Situ

MGI Mouse Phenotypes related to Uterus Carcinoma in Situ:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.83 CD4 CDKN2A FHIT GP5 GP6 INSM1
2 integument MP:0010771 9.28 CD4 CDKN2A FHIT GP6 KRT17 LGALS7

Drugs & Therapeutics for Uterus Carcinoma in Situ

Search Clinical Trials, NIH Clinical Center for Uterus Carcinoma in Situ

Genetic Tests for Uterus Carcinoma in Situ

Anatomical Context for Uterus Carcinoma in Situ

Organs/tissues related to Uterus Carcinoma in Situ:

FMA: Uterus
MalaCards : Uterus, Thyroid, Lung

Publications for Uterus Carcinoma in Situ

Articles related to Uterus Carcinoma in Situ:

# Title Authors PMID Year
1
[A resected case of triple cancer in the uterus, lung and thyroid]. 62
2681446 1989

Variations for Uterus Carcinoma in Situ

Expression for Uterus Carcinoma in Situ

Search GEO for disease gene expression data for Uterus Carcinoma in Situ.

Pathways for Uterus Carcinoma in Situ

Pathways related to Uterus Carcinoma in Situ according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.26 TP53 CDKN2A
2 9.85 TP53 CDKN2A

GO Terms for Uterus Carcinoma in Situ

Biological processes related to Uterus Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme-linked receptor protein signaling pathway GO:0007167 9.26 GP6 CD4
2 hemostasis GO:0007599 8.8 SERPIND1 GP6 GP5

Molecular functions related to Uterus Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 galactoside binding GO:0016936 8.8 LGALS7B LGALS7

Sources for Uterus Carcinoma in Situ

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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