MCID: UTR009
MIFTS: 26

Uterus Carcinoma in Situ

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Uterus Carcinoma in Situ

MalaCards integrated aliases for Uterus Carcinoma in Situ:

Name: Uterus Carcinoma in Situ 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:9108
ICD9CM 35 233.2
UMLS 73 C0154086

Summaries for Uterus Carcinoma in Situ

Disease Ontology : 12 An in situ carcinoma that is located in the uterus.

MalaCards based summary : Uterus Carcinoma in Situ is related to cervicitis and chronic cervicitis. An important gene associated with Uterus Carcinoma in Situ is SERPIND1 (Serpin Family D Member 1), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Oncogene Induced Senescence. Affiliated tissues include uterus, lung and skin, and related phenotype is mortality/aging.

Related Diseases for Uterus Carcinoma in Situ

Diseases related to Uterus Carcinoma in Situ via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 cervicitis 10.2 CDKN2A SERPIND1
2 chronic cervicitis 10.2 GP6 SERPIND1
3 balanoposthitis 10.2 CDKN2A GP6
4 bladder squamous cell carcinoma 10.2 CDKN2A TP53
5 keratinizing squamous cell carcinoma 10.2 CDKN2A TP53
6 spitz nevus 10.2 CDKN2A TP53
7 bladder carcinoma in situ 10.2 CDKN2A TP53
8 scrotal carcinoma 10.2 CDKN2A TP53
9 nasal cavity adenocarcinoma 10.2 CDKN2A TP53
10 bartholin's gland disease 10.2 CDKN2A TP53
11 anal squamous cell carcinoma 10.2 CDKN2A TP53
12 megaesophagus 10.2 CDKN2A TP53
13 glycogen-rich clear cell breast carcinoma 10.2 CDKN2A TP53
14 gastric adenosquamous carcinoma 10.2 CDKN2A TP53
15 oral leukoplakia 10.2 CDKN2A TP53
16 meningeal melanomatosis 10.2 CDKN2A TP53
17 suppressor of tumorigenicity 3 10.2 CDKN2A TP53
18 dedifferentiated liposarcoma 10.2 CDKN2A TP53
19 endocervical adenocarcinoma 10.2 CDKN2A TP53
20 cervix small cell carcinoma 10.2 CDKN2A TP53
21 necrotizing sialometaplasia 10.2 CDKN2A TP53
22 verrucous carcinoma 10.2 CDKN2A TP53
23 tongue disease 10.2 CDKN2A TP53
24 biliary tract neoplasm 10.2 CDKN2A TP53
25 optic nerve neoplasm 10.2 CDKN2A TP53
26 juvenile pilocytic astrocytoma 10.2 CDKN2A TP53
27 tonsil cancer 10.2 CDKN2A TP53
28 eccrine sweat gland neoplasm 10.2 KRT17 TP53
29 recessive dystrophic epidermolysis bullosa 10.1 CDKN2A TP53
30 cervical adenosarcoma 10.1 GP5 GP6
31 vulva cancer 10.1 CDKN2A TP53
32 squamous cell papilloma 10.1 CDKN2A TP53
33 barrett's adenocarcinoma 10.1 CDKN2A TP53
34 ampulla of vater cancer 10.1 KRT17 TP53
35 herpangina 10.1 GP5 GP6
36 oropharynx cancer 10.1 CDKN2A TP53
37 anus disease 10.1 CDKN2A GP5
38 cervix carcinoma 10.1 CDKN2A TP53
39 laryngeal disease 10.1 CDKN2A SERPIND1 TP53
40 pancreatic ductal carcinoma 10.1 CDKN2A TP53
41 rectal disease 10.1 CDKN2A GP5
42 skin squamous cell carcinoma 10.1 CDKN2A TP53
43 anogenital venereal wart 10.1 CDKN2A GP6 TP53
44 penile disease 10.1 CDKN2A GP6 TP53
45 vulva squamous cell carcinoma 10.1 CDKN2A KRT17 TP53
46 basaloid squamous cell carcinoma 10.1 CDKN2A KRT17 TP53
47 inverted papilloma 10.1 CDKN2A TP53
48 actinic keratosis 10.1 CDKN2A KRT17 TP53
49 early invasive cervical adenocarcinoma 10.0 CDKN2A INSM1
50 fallopian tube endometrioid adenocarcinoma 10.0 CDKN2A INSM1

Graphical network of the top 20 diseases related to Uterus Carcinoma in Situ:



Diseases related to Uterus Carcinoma in Situ

Symptoms & Phenotypes for Uterus Carcinoma in Situ

MGI Mouse Phenotypes related to Uterus Carcinoma in Situ:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.28 CDKN2A CINP COL27A1 GP6 INSM1 KLHL40

Drugs & Therapeutics for Uterus Carcinoma in Situ

Search Clinical Trials , NIH Clinical Center for Uterus Carcinoma in Situ

Genetic Tests for Uterus Carcinoma in Situ

Anatomical Context for Uterus Carcinoma in Situ

MalaCards organs/tissues related to Uterus Carcinoma in Situ:

41
Uterus, Lung, Skin, Tongue, Tonsil, Cervix, Thyroid

The Foundational Model of Anatomy Ontology organs/tissues related to Uterus Carcinoma in Situ:

19
The Uterus

Publications for Uterus Carcinoma in Situ

Variations for Uterus Carcinoma in Situ

Expression for Uterus Carcinoma in Situ

Search GEO for disease gene expression data for Uterus Carcinoma in Situ.

Pathways for Uterus Carcinoma in Situ

GO Terms for Uterus Carcinoma in Situ

Biological processes related to Uterus Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell cycle GO:0007049 9.62 CDKN2A CINP INSM1 TP53
2 blood coagulation GO:0007596 9.43 GP5 GP6 SERPIND1
3 positive regulation of cell cycle arrest GO:0071158 9.16 INSM1 TP53
4 replicative senescence GO:0090399 8.96 CDKN2A TP53
5 hemostasis GO:0007599 8.8 GP5 GP6 SERPIND1

Molecular functions related to Uterus Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 disordered domain specific binding GO:0097718 8.62 CDKN2A TP53

Sources for Uterus Carcinoma in Situ

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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