MCID: VGN016
MIFTS: 21

Vaginal Benign Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vaginal Benign Neoplasm

MalaCards integrated aliases for Vaginal Benign Neoplasm:

Name: Vaginal Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060114

Summaries for Vaginal Benign Neoplasm

Disease Ontology : 12 A female reproductive organ benign neoplasm that is located in the vagina.

MalaCards based summary : Vaginal Benign Neoplasm is related to vaginal adenoma and vagina leiomyoma. An important gene associated with Vaginal Benign Neoplasm is APELA (Apelin Receptor Early Endogenous Ligand), and among its related pathways/superpathways is Aromatase Inhibitor Pathway (Breast Cell), Pharmacodynamics. Affiliated tissues include vagina, and related phenotypes are cardiovascular system and endocrine/exocrine gland

Related Diseases for Vaginal Benign Neoplasm

Diseases related to Vaginal Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 303)
# Related Disease Score Top Affiliating Genes
1 vaginal adenoma 26.9 SYP STK11 PGF OXT KRT7 KRT20
2 vagina leiomyoma 11.3
3 vaginal mullerian papilloma 11.3
4 benign vaginal carcinosarcoma 11.3
5 vaginal squamous papilloma 11.3
6 thymus adenocarcinoma 10.5 KRT20 CDX2
7 eyelid benign neoplasm 10.5 KRT20 CHGA
8 urethral villous adenoma 10.4 KRT7 KRT20
9 nephrogenic adenoma of urinary bladder 10.4 KRT7 KRT20
10 intrahepatic bile duct adenoma 10.4 KRT7 KRT20
11 bile duct adenoma 10.4 KRT7 KRT20
12 atrophic vulva 10.4 KRT7 KRT20
13 anal canal paget's disease 10.4 KRT7 CDX2
14 anal paget's disease 10.4 KRT7 CDX2
15 anal gland adenocarcinoma 10.4 KRT7 CDX2
16 ureter adenocarcinoma 10.4 KRT7 CDX2
17 pancreatic foamy gland adenocarcinoma 10.4 KRT7 CDX2
18 adenosquamous colon carcinoma 10.4 KRT7 CDX2
19 nasal cavity adenocarcinoma 10.4 KRT7 CDX2
20 anus adenocarcinoma 10.4 KRT7 CDX2
21 bartholin's gland carcinoma 10.4 KRT7 CDX2
22 placenta praevia 10.4 PGF OXT
23 vulvar apocrine adenocarcinoma 10.4 KRT7 KRT20
24 eyelid carcinoma 10.4 KRT7 KRT20
25 subserous uterine fibroid 10.4 OXT CYP19A1
26 bile duct cystadenocarcinoma 10.4 KRT7 KRT20
27 mucinous intrahepatic cholangiocarcinoma 10.4 KRT7 CDX2
28 rectosigmoid junction neoplasm 10.4 KRT7 KRT20
29 ovarian seromucinous carcinoma 10.4 KRT7 CDX2
30 sigmoid neoplasm 10.4 KRT7 KRT20
31 bartholin's gland disease 10.4 KRT7 CDX2
32 intratubular embryonal carcinoma 10.4 KRT7 KRT20
33 malignant syringoma 10.4 KRT7 KRT20
34 transverse colon cancer 10.4 KRT7 KRT20
35 mammographic density 10.4 CYP1A1 CYP19A1
36 colonic lymphangioma 10.4 KRT7 KRT20
37 papillary transitional carcinoma 10.4 KRT7 KRT20
38 ovarian primitive germ cell tumor 10.4 KRT7 CDX2
39 anal canal adenocarcinoma 10.4 KRT7 CDX2
40 meibomian cyst 10.4 KRT7 KRT20
41 ovarian brenner tumor 10.4 KRT7 KRT20
42 pulmonary hemosiderosis 10.4 KRT7 APELA
43 eccrine sweat gland cancer 10.4 KRT7 KRT20
44 nephrogenic adenoma of the urethra 10.3 KRT7 KRT20
45 pancreatic mucinous cystadenoma 10.3 KRT7 KRT20
46 hypoactive sexual desire disorder 10.3 OXT CYP19A1
47 cervical mucinous adenocarcinoma 10.3 STK11 KRT7
48 nonmucinous bronchioloalveolar adenocarcinoma 10.3 KRT20 ESR2
49 papillary cystadenocarcinoma 10.3 KRT7 KRT20
50 mucinous stomach adenocarcinoma 10.3 KRT7 CDX2

Graphical network of the top 20 diseases related to Vaginal Benign Neoplasm:



Diseases related to Vaginal Benign Neoplasm

Symptoms & Phenotypes for Vaginal Benign Neoplasm

MGI Mouse Phenotypes related to Vaginal Benign Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.09 CDX2 CHGA CTNNB1 CYP19A1 ESR2 IGF2
2 endocrine/exocrine gland MP:0005379 10.07 CDX2 CHGA CTNNB1 CYP19A1 CYP1A1 ESR2
3 growth/size/body region MP:0005378 10.02 CDX2 CHGA CTNNB1 CYP19A1 CYP1A1 ESR2
4 homeostasis/metabolism MP:0005376 10 CDX2 CHGA CTNNB1 CYP19A1 CYP1A1 ESR2
5 digestive/alimentary MP:0005381 9.95 CDX2 CTNNB1 CYP19A1 ESR2 IGF2 OXT
6 no phenotypic analysis MP:0003012 9.63 CHGA CTNNB1 CYP1A1 ESR2 IGF2 STK11
7 renal/urinary system MP:0005367 9.56 CHGA CTNNB1 CYP19A1 ESR2 IGF2 KRT7
8 reproductive system MP:0005389 9.28 CDX2 CHGA CTNNB1 CYP19A1 ESR2 HSPA4

Drugs & Therapeutics for Vaginal Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Vaginal Benign Neoplasm

Genetic Tests for Vaginal Benign Neoplasm

Anatomical Context for Vaginal Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Vaginal Benign Neoplasm:

19
Vagina

Publications for Vaginal Benign Neoplasm

Variations for Vaginal Benign Neoplasm

Expression for Vaginal Benign Neoplasm

Search GEO for disease gene expression data for Vaginal Benign Neoplasm.

Pathways for Vaginal Benign Neoplasm

Pathways related to Vaginal Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.23 ESR2 CYP19A1

GO Terms for Vaginal Benign Neoplasm

Biological processes related to Vaginal Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 embryonic heart tube development GO:0035050 9.16 CTNNB1 APELA
2 anterior/posterior axis specification GO:0009948 8.96 CTNNB1 CDX2
3 response to estradiol GO:0032355 8.8 OXT CYP19A1 CTNNB1

Molecular functions related to Vaginal Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 OXT IGF2 APELA

Sources for Vaginal Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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