MCID: VGN018
MIFTS: 17

Vaginal Carcinosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vaginal Carcinosarcoma

MalaCards integrated aliases for Vaginal Carcinosarcoma:

Name: Vaginal Carcinosarcoma 12 15 17 71
Malignant Vaginal Mixed Epithelial and Mesenchymal Tumor 12
Vaginal Mixed Epithelial and Mesenchymal Tumor 12
Vaginal Malignant Mixed Mesodermal Tumor 12
Vaginal Malignant Mixed Mullerian Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:136
UMLS 71 C1512974 C1519918 C1519924

Summaries for Vaginal Carcinosarcoma

Disease Ontology : 12 A vaginal carcinoma that has material basis in connective tissue.

MalaCards based summary : Vaginal Carcinosarcoma, also known as malignant vaginal mixed epithelial and mesenchymal tumor, is related to vaginal adenosarcoma and benign vaginal carcinosarcoma. An important gene associated with Vaginal Carcinosarcoma is MME (Membrane Metalloendopeptidase). Related phenotype is Synthetic lethal with c-Myc after tamoxifen stimulation.

Related Diseases for Vaginal Carcinosarcoma

Diseases in the Vaginal Carcinosarcoma family:

Benign Vaginal Carcinosarcoma

Diseases related to Vaginal Carcinosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 vaginal adenosarcoma 31.0 MTOR MME CRP
2 benign vaginal carcinosarcoma 11.2
3 vaginal spindle cell epithelioma 11.1
4 orbital cellulitis 10.0 MME CRP
5 acute orbital inflammation 10.0 MME CRP
6 polyclonal hypergammaglobulinemia 10.0 MME CRP
7 plasma protein metabolism disease 9.9 MME CRP
8 splenic disease 9.9 MME CRP
9 leukocyte disease 9.9 MME CRP
10 hydronephrosis 9.9 MME CRP
11 carcinosarcoma 9.9
12 congestive heart failure 9.9 MME CRP
13 amyloidosis 9.9 MME CRP
14 hemorrhagic disease 9.8 MME CRP
15 heart cancer 9.8 MTOR CRP
16 multicentric castleman disease 9.8 MTOR CRP
17 castleman disease 9.8 MTOR CRP
18 spinal cord disease 9.8 MTOR CRP
19 exanthem 9.8 MTOR CRP
20 intestinal obstruction 9.8 MTOR CRP
21 hyperphosphatemia 9.8 MTOR CRP
22 cardiovascular system disease 9.8 MME CRP
23 ovarian mixed germ cell neoplasm 9.8 MTOR MME
24 blood platelet disease 9.8 MTOR CRP
25 blood coagulation disease 9.8 MTOR CRP
26 kidney benign neoplasm 9.8 MTOR MME
27 angiomyolipoma 9.8 MTOR MME
28 renal cell carcinoma, papillary, 1 9.8 MTOR MME
29 myelofibrosis 9.7 MTOR CRP
30 cholangiocarcinoma 9.7 MTOR MME
31 mantle cell lymphoma 9.7 MTOR MME
32 peripheral nervous system disease 9.7 MTOR CRP
33 clear cell renal cell carcinoma 9.7 MTOR MME
34 deficiency anemia 9.6 MME CRP
35 basal cell carcinoma 9.5 MTOR MME
36 hypertension, essential 9.5 MTOR MME CRP
37 alzheimer disease 9.4 MTOR MME CRP
38 disease of mental health 9.3 MTOR MME CRP

Graphical network of the top 20 diseases related to Vaginal Carcinosarcoma:



Diseases related to Vaginal Carcinosarcoma

Symptoms & Phenotypes for Vaginal Carcinosarcoma

GenomeRNAi Phenotypes related to Vaginal Carcinosarcoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with c-Myc after tamoxifen stimulation GR00215-A 8.62 CRP MTOR

Drugs & Therapeutics for Vaginal Carcinosarcoma

Search Clinical Trials , NIH Clinical Center for Vaginal Carcinosarcoma

Genetic Tests for Vaginal Carcinosarcoma

Anatomical Context for Vaginal Carcinosarcoma

Publications for Vaginal Carcinosarcoma

Articles related to Vaginal Carcinosarcoma:

# Title Authors PMID Year
1
Primary carcinosarcoma of the vagina. 61
12588439 2003
2
[Vaginal carcinosarcoma (report of a case)]. 61
4832728 1974

Variations for Vaginal Carcinosarcoma

Expression for Vaginal Carcinosarcoma

Search GEO for disease gene expression data for Vaginal Carcinosarcoma.

Pathways for Vaginal Carcinosarcoma

GO Terms for Vaginal Carcinosarcoma

Biological processes related to Vaginal Carcinosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of neurogenesis GO:0050769 8.62 MTOR MME

Sources for Vaginal Carcinosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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