MCID: VGN019
MIFTS: 47

Vaginal Discharge

Categories: Reproductive diseases
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Aliases & Classifications for Vaginal Discharge

MalaCards integrated aliases for Vaginal Discharge:

Name: Vaginal Discharge 11 43 14 16 75

Classifications:



External Ids:

Disease Ontology 11 DOID:3767
MeSH 43 D019522
SNOMED-CT 68 70856007
UMLS 71 C0227791

Summaries for Vaginal Discharge

Disease Ontology: 11 A vaginal disease that is characterized by the presence of discharge.

MalaCards based summary: Vaginal Discharge is related to leukorrhea and trichomoniasis. An important gene associated with Vaginal Discharge is CRP (C-Reactive Protein), and among its related pathways/superpathways are ERK Signaling and TGF-Beta Pathway. The drugs Estrogens, Conjugated (USP) and Fluconazole have been mentioned in the context of this disorder. Affiliated tissues include cervix, uterus and breast, and related phenotypes are homeostasis/metabolism and neoplasm

Wikipedia: 75 Vaginal discharge is a mixture of liquid, cells, and bacteria that lubricate and protect the vagina.... more...

Related Diseases for Vaginal Discharge

Diseases related to Vaginal Discharge via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1050)
# Related Disease Score Top Affiliating Genes
1 leukorrhea 32.3 ESR1 CRP
2 trichomoniasis 31.5 TNF SLPI IL6 IL1B IL10 CXCL8
3 bacterial vaginosis 31.4 TNF SLPI IL6 IL1B IL1A IL10
4 chlamydia 31.4 TNF IL6 IL1B IL1A IL10 CXCL8
5 vaginitis 31.1 TNF SLPI IL6 IL1B IL1A IL10
6 candidiasis 30.6 TNF IL6 IL1B IL1A IL10 CXCL8
7 syphilis 30.5 TNF CRP CD4 ALB
8 endometritis 30.5 TNF PGR OXT IL6 IL1B HP
9 cervicitis 30.5 TNF IL6 IL1B IL10 CXCL8 CD4
10 haemophilus influenzae 30.4 TNF IL1B CXCL8
11 postmenopausal atrophic vaginitis 30.4 OXT GNRH1 ESR1 CYP19A1
12 newborn respiratory distress syndrome 30.2 CXCL8 CRP ALB
13 cystitis 30.1 TNF IL6 CXCL8 CRP
14 leiomyoma, uterine 30.1 PGR GNRH1 ESR1 CYP19A1
15 headache 30.1 TNF CXCL8 ALB
16 varicose veins 30.1 TNF IL6 ESR1 CXCL8
17 anovulation 30.0 HP GNRH1 CYP19A1 CRP
18 gestational diabetes 30.0 TNF IL6 IL1B CRP
19 adenomyosis 30.0 IL10 ESR1 CYP19A1
20 pneumothorax 30.0 PGR GNRH1 CRP
21 leiomyoma 29.9 PGR GNRH1 ESR1 CYP19A1
22 urinary tract infection 29.9 TNF IL6 IL1B IL10 CXCL8 CRP
23 inflammatory bowel disease 1 29.9 TNF IL6 IL1B IL10
24 myositis 29.8 TNF IL6 IL1B IL1A
25 pemphigoid 29.8 TNF IL6 IL1B IL10 CXCL8
26 thrombocytosis 29.7 IL6 IL1B IL1A CRP ALB
27 vasculitis 29.7 TNF IL6 IL1B IL10 CXCL8 CRP
28 ulcerative colitis 29.6 TNF IL6 IL1B IL10 CXCL8 CRP
29 urethritis 29.6 TNF IL6 IL1B IL10 CXCL8 CRP
30 lymphangioma 29.6 TNF IL6 IL1B IL10 CXCL8 CEACAM5
31 ovarian cyst 29.5 PGR GNRH1 ESR1 CYP19A1 CRP CEACAM5
32 diarrhea 29.5 TNF IL6 IL1B IL10 CXCL8 ALB
33 schistosomiasis 29.5 TNF IL1A IL10 CRP ALB
34 colitis 29.5 TNF IL6 IL1B IL10 CXCL8 CRP
35 dermatitis 29.4 TNF IL6 IL1B IL1A IL10 CXCL8
36 hepatitis b 29.4 TNF IL6 CXCL8 ALB
37 appendicitis 29.4 TNF IL6 IL1B IL10 CXCL8 CRP
38 acquired immunodeficiency syndrome 29.4 TNF IL6 IL1B IL10 CRP CD4
39 leprosy 3 29.4 TNF IL6 IL1B IL10 CXCL8 CD4
40 immune deficiency disease 29.1 TNF SLPI IL6 IL1B IL1A IL10
41 fungal infectious disease 29.1 TNF IL6 IL1B IL1A IL10 CXCL8
42 endometriosis 29.1 PGR IL6 IL1B IL1A GNRH1 ESR1
43 crohn's disease 29.1 TNF IL6 IL1B IL10 HP CXCL8
44 respiratory failure 28.9 TNF IL6 IL1B IL1A IL10 CXCL8
45 skin disease 28.7 TNF IL6 IL1B IL1A IL10 ESR1
46 connective tissue disease 28.7 TNF IL6 IL1B IL1A IL10 ESR1
47 pelvic inflammatory disease 11.3
48 uterine carcinosarcoma 11.2
49 trichomonas vaginalis trichomoniasis 11.1
50 fallopian tube carcinoma 11.1

Graphical network of the top 20 diseases related to Vaginal Discharge:



Diseases related to Vaginal Discharge

Symptoms & Phenotypes for Vaginal Discharge

MGI Mouse Phenotypes related to Vaginal Discharge:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.33 ALB CD4 CEACAM5 CRP CYP19A1 ESR1
2 neoplasm MP:0002006 10.22 ALB CEACAM5 ESR1 GNRH1 HP IL10
3 endocrine/exocrine gland MP:0005379 10.15 ALB CD4 CEACAM5 CYP19A1 ESR1 GNRH1
4 liver/biliary system MP:0005370 10.09 ALB CYP19A1 ESR1 GNRH1 HP IL10
5 cardiovascular system MP:0005385 10.07 ALB CEACAM5 CRP CYP19A1 ESR1 HP
6 muscle MP:0005369 10.06 ALB CEACAM5 CYP19A1 ESR1 IL10 IL6
7 immune system MP:0005387 10.03 ALB CD4 CEACAM5 CRP CYP19A1 ESR1
8 digestive/alimentary MP:0005381 10.02 ALB CD4 CEACAM5 CYP19A1 ESR1 GNRH1
9 hematopoietic system MP:0005397 9.77 CD4 CEACAM5 CYP19A1 ESR1 GNRH1 HP
10 integument MP:0010771 9.36 CD4 CYP19A1 ESR1 GNRH1 IL10 IL1A

Drugs & Therapeutics for Vaginal Discharge

Drugs for Vaginal Discharge (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Estrogens, Conjugated (USP) Phase 4
2
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
3
Secnidazole Approved Phase 3 3366-95-8
4
Tinidazole Approved, Investigational Phase 3 19387-91-8 5479
5
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
6
Mepivacaine Approved, Vet_approved Phase 3 96-88-8, 1722-62-9 4062
7
Clindamycin Approved, Vet_approved Phase 3 18323-44-9, 24729-96-2 29029
8 Alkylating Agents Phase 3
9 Anti-Arrhythmia Agents Phase 3
10 Sodium Channel Blockers Phase 3
11 Anesthetics, Local Phase 3
12 Anesthetics Phase 3
13 Diuretics, Potassium Sparing Phase 3
14
Clindamycin phosphate Phase 3 32603
15 Clindamycin palmitate Phase 3

Interventional clinical trials:

(show all 14)
# Name Status NCT ID Phase Drugs
1 Postmenopausal Pessary Users: Estrogen Versus Trimosan Unknown status NCT03943823 Phase 4 Estrogen vaginal cream;Trimo-San vaginal gel
2 Safety and Clinical and Microbiological Efficacy of the Combination of Fluconazole and Secnidazole for the Treatment of Symptomatic Vaginal Discharge. Bogotá D. C. Colombia. Completed NCT02111629 Phase 3 Fluconazole and Secnidazole
3 A Randomised Controlled Trial of Single Dose Tinidazole+Fluconazole Versus Longer Courses of Metronidazole+Clotrimazole in the Management of West African Women With Vaginal Discharge Completed NCT00313131 Phase 3 tinidazole+fluconazole vs metronidazole+clotrimazole
4 Randomised Controlled Trial to Evaluate the Efficacy of Local Anaesthetic Application in Spray for the Repair of 1st- 2nd Perineal Lacerations Following Vaginal Delivery Completed NCT05201313 Phase 3 Lidocaine Hydrochloride;Mepivacaine Injection
5 A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Women Completed NCT02210689 Phase 3 clindamycin phosphate vaginal cream 2%
6 Phase III, Multicenter, Randomized, Parallel, Open Label, Controlled and Comparative Study to Evaluate the Efficacy and Safety of the Association of Clotrimazole 200mg and Metronidazole 0,75% (Colpistatin 5DT®) Compared to Gynecological Flagyl®(Metronidazole 100mg/g) and the Vaginal Cream Gino-Canesten® 3 (Clotrimazole 20mg/g) in the Syndromic Treatment of the Vaginal Discharge From Different Etiologies. Withdrawn NCT02713139 Phase 3 Clotrimazole + Metronidazole;Metronidazole;Clotrimazole
7 Vaginal Creams for Reduction of Vaginal Discharge and Erosion in Patients Using Ring With Support or Gellhorn Pessaries to Reduce Pelvic Organ Prolapse Withdrawn NCT02316249 Phase 2 Estradiol
8 Validity of Patient-Collected Wet Mounts Completed NCT02641717
9 Evaluate the Agreement of High-risk Human Papillomavirus Type Between Self-collected Vaginal Discharge Sample Using "HygeiaTouch Self Sampling Kit for Woman" and Physician Collected Sample From the Cervix Completed NCT04472377
10 Prospective Evaluation of the Impact of Bacterial Vaginosis and Its Treatment on Mucosal Susceptibility to HIV-1 Infection and Endpoints of Cervico-Vaginal Safety Completed NCT01347632 Metronidazole
11 Epidemiology and Clinico-investigative Study of Abnormal Vaginal Discharge During Pregnancy Recruiting NCT04719754
12 Evaluation of a Novel Female Hygiene Device for Postcoital Discomfort Recruiting NCT04885556
13 EMMI - Emättimen Mikrobiomi - Emättimen ja Suun Limakalvojen Vuorovaikutus Recruiting NCT02898818
14 Using Micro Electro Mechanical Systems to Detect the Air of Vaginal Discharge Not yet recruiting NCT05557318

Search NIH Clinical Center for Vaginal Discharge

Cochrane evidence based reviews: vaginal discharge

Genetic Tests for Vaginal Discharge

Anatomical Context for Vaginal Discharge

Organs/tissues related to Vaginal Discharge:

MalaCards : Cervix, Uterus, Breast, Lymph Node, Ovary, Placenta, Colon

Publications for Vaginal Discharge

Articles related to Vaginal Discharge:

(show top 50) (show all 3457)
# Title Authors PMID Year
1
Effect of estrogen on vaginal complications of pessary use: a systematic review and meta-analysis. 62
35695119 2022
2
Does monthly self-management of vaginal ring pessaries reduce the rate of adverse events? A clinical audit. 62
36120118 2022
3
Outcomes of Pessary Use at 1 Year in Women Treated for Pelvic Organ Prolapse in a Large Multicenter Registry: Developed by the Pelvic Floor Disorders Registry. 62
36409637 2022
4
Concomitant vesicovaginal fistula and rectovaginal fistula in a patient with a neglected pessary placed for pelvic organ prolapse. 62
36041957 2022
5
Case 308: Van Wyk-Grumbach Syndrome. 62
36409615 2022
6
Abnormal vaginal discharge among women of reproductive age in sub-Saharan Africa: the need for a paradigm shift from a syndromic approach to specific pathogen identification and directed treatment. 62
36467508 2022
7
Effectivity and efficacy probiotics for Bacterial Vaginosis treatments: Meta-analysis. 62
36262267 2022
8
Plasma activin A concentrations during late gestation in Thoroughbred mares with abnormal pregnancies. 62
36470514 2022
9
Cerclage in surgically shortened uterine cervix and pregnancy outcome: A retrospective comparison between the abdominal and vaginal procedures. 62
36110090 2022
10
Low prevalence of macrolide resistance in Mycoplasma genitalium infections in a cohort of pregnant women living with human immunodeficiency virus. 62
36218027 2022
11
Genes, exposures, and interactions on preterm birth risk: an exploratory study in an Argentine population. 62
35976607 2022
12
Female Genital Tuberculosis. 62
36447614 2022
13
Combination of clinical and MRI features in diagnosing ovarian granulosa cell tumor: A comparison with other ovarian sex cord-gonadal stromal tumors. 62
36434968 2022
14
Case of suspected lobular endocervical glandular hyperplasia in a cervical cystic lesion during pregnancy. 62
36447665 2022
15
Effect of dose and frequency of prostaglandin F2α treatments during a 7-day Ovsynch protocol with an intravaginal progesterone releasing device on luteal regression and pregnancy outcomes in lactating Holstein cows. 62
36460496 2022
16
Surgical outcomes of laparoscopic trachelectomy following supracervical hysterectomy: a multicenter study. 62
36254598 2022
17
Quantitative system for diagnosis of vulvovaginal candidiasis. 62
35717682 2022
18
Neutrophil Extracellular Traps Mediate Bovine Endometrial Epithelial Cell Pyroptosis in Dairy Cows with Endometritis. 62
36430491 2022
19
Adenocarcinoma of the uterine cervix, gastric-type (GAS): a review of the literature focused on pathology and multimodality imaging. 62
36334123 2022
20
Intrauterine infusion of a pathogenic bacterial cocktail is associated with the development of clinical metritis in postpartum multiparous Holstein cows. 62
36400620 2022
21
Knowledge, experiences, and practices of women affected by female genital schistosomiasis in rural Madagascar: A qualitative study on disease perception, health impairment and social impact. 62
36342912 2022
22
Combined use of non-laboratory methods for the practical diagnosis of endometritis in postpartum dairy cows. 62
36002983 2022
23
Association between prepartum nonesterified fatty acid serum concentrations and postpartum diseases in dairy cows. 62
36175243 2022
24
Microfilaria in cervicovaginal Pap smears: A common parasite hiding in an unusual site: Short series of four cases with literature review. 62
36269616 2022
25
Association of clinical signs of chorioamnionitis with histological chorioamnionitis and neonatal outcomes. 62
36195455 2022
26
Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case report. 62
36389632 2022
27
Fulminant Sepsis and Perinatal Death at 23 Weeks Due to Fusobacterium nucleatum. 62
36218233 2022
28
Prevalence of subclinical endometritis in dairy cows that recovered after treatment of clinical endometritis with cephapirin and PGF2α. 62
36108547 2022
29
Consuming an All-Meat Ketogenic Diet for the Long-Term Management of Candida Vulvovaginitis and Vaginal Hidradenitis Suppurativa: A 47-Month Follow-Up Case Report. 62
36285109 2022
30
Trichomoniasis refractory to 5-nitroimidazole therapy in Trinidad. 62
36214266 2022
31
Myometritis with pelvic septic vein thrombophlebitis secondary to Fusobacterium necrophorum sepsis. 62
36229077 2022
32
Assessment of the Performance of the Aptima Bacterial Vaginosis Assay Over a 3-Month Period in a French Hospital. 62
35980223 2022
33
Type C1 radical hysterectomy in advanced squamous cell carcinoma of the cervix postdefinitive concurrent chemoradiation: An argument. 62
36412410 2022
34
Changes in the Vaginal Microbiota of Women With Secondary Localized Provoked Vulvodynia. 62
35943448 2022
35
Risk factors for neonatal sepsis in Sub-Saharan Africa: a systematic review with meta-analysis. 62
36253895 2022
36
Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions. 62
35577062 2022
37
Leaving the Placenta In Situ in Placenta Accreta Spectrum Disorders: A Single-Center Case Series. 62
35752168 2022
38
Clinical characteristics and a 2-year follow-up of unsatisfactory conventional Pap smears: a retrospective case-control study. 62
36100639 2022
39
Effect of feeding rumen-protected lysine through the transition period on postpartum uterine health of dairy cows. 62
35940923 2022
40
DETERMINATION OF THE SENSITIVITY OF GARDNERELLA VAGINALIS TO FENTICONAZOLE. 62
36427832 2022
41
Exploring of probiotic potential vaginal lactobacillus isolates from healthy women against Gardnerella vaginalis and Caenorhabditis elegans model testing. 62
35633296 2022
42
Assessment of excessive vaginal discharge among women who presented to Phuentsholing General Hospital: A hospital-based study. 62
36090622 2022
43
Progression of Peritoneal Mesothelioma In Situ to Invasive Mesothelioma Arising in the Setting of Endometriosis With Germline BAP1 Mutation: A Case Report. 62
34723845 2022
44
Vulvar Pruritus in Postmenopausal Diabetic Women With Candidiasis Secondary to Sodium-Glucose Cotransporter Receptor-2 Inhibitors. 62
36129363 2022
45
Metastatic Cholangiocarcinoma to the Uterus Morphologically Imitating Primary Intestinal-type Endometrioid Adenocarcinoma. 62
36044318 2022
46
Case 308. 62
35877547 2022
47
The effect of pre-calving injection of trace mineral supplements on periparturient disease incidence in pasture based dairy cows. 62
35842221 2022
48
18-F fluorodeoxyglucose positron emission tomography/computed tomography findings of bilateral primary fallopian tube carcinoma and metastasis to the uterus: a case report and literature review. 62
36039605 2022
49
In Vitro Effect of 5-Nitroimidazole Drugs against Trichomonas vaginalis Clinical Isolates. 62
35863010 2022
50
Peptoniphilus indolicus infection in a pregnant woman: a case report. 62
35481409 2022

Variations for Vaginal Discharge

Expression for Vaginal Discharge

Search GEO for disease gene expression data for Vaginal Discharge.

Pathways for Vaginal Discharge

Pathways related to Vaginal Discharge according to GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.85 CD4 CXCL8 ESR1 GNRH1 IL10 IL1A
2
Show member pathways
13.56 TNF MAPK8IP1 IL6 IL1B IL1A IL10
3
Show member pathways
13.43 CD4 CXCL8 GNRH1 IL10 IL1A IL1B
4
Show member pathways
13.33 TNF IL6 IL1B IL1A IL10 CXCL8
5
Show member pathways
13.33 CD4 CXCL8 GNRH1 IL10 IL1A IL1B
6
Show member pathways
12.84 TNF IL6 IL1B IL1A CXCL8
7
Show member pathways
12.72 GNRH1 IL1A IL1B IL6 TNF
8
Show member pathways
12.67 TNF IL6 IL1B IL1A IL10 GNRH1
9
Show member pathways
12.64 TNF IL6 IL1B IL1A CXCL8
10
Show member pathways
12.61 TNF IL6 IL1B IL10 CD4
11
Show member pathways
12.51 TNF IL6 IL1B CXCL8
12
Show member pathways
12.46 TNF IL6 IL1B IL1A CXCL8
13 12.4 TNF MAPK8IP1 IL1B IL1A
14
Show member pathways
12.36 TNF IL6 IL1B IL1A CXCL8
15 12.19 TNF IL6 IL1B IL1A IL10 CXCL8
16 12.14 TNF IL6 IL1B IL1A IL10
17 12.05 CD4 CEACAM5 IL10 IL6 TNF
18 12.04 TNF IL6 IL1B IL1A CXCL8
19 11.99 IL6 IL1B IL1A CXCL8
20
Show member pathways
11.97 TNF IL6 IL1B IL10 CD4
21 11.91 TNF IL1B IL1A IL10 CXCL8
22 11.85 TNF IL1B IL10 CD4
23
Show member pathways
11.83 IL6 CXCL8 CRP CD4
24 11.83 TNF IL6 IL1B IL1A IL10 CXCL8
25 11.82 TNF IL6 IL1B CXCL8
26 11.79 TNF IL6 IL10 CRP
27 11.79 CD4 IL10 IL1B IL6 TNF
28 11.77 IL6 IL10 ESR1 CXCL8
29 11.76 IL6 IL10 CD4
30 11.72 IL6 IL1B CD4
31 11.72 TNF IL6 IL1B CXCL8
32
Show member pathways
11.68 TNF IL6 IL1A IL10
33
Show member pathways
11.65 TNF IL6 IL1B IL1A CXCL8
34 11.63 IL6 ESR1 CXCL8
35 11.62 TNF IL6 IL1A IL10 CXCL8
36 11.59 TNF IL1A IL10
37 11.59 TNF IL6 IL1B IL1A IL10
38 11.58 TNF IL10 CXCL8
39 11.58 TNF IL6 CXCL8
40 11.53 TNF IL6 IL1A
41 11.42 CYP19A1 IL1A IL1B IL6 TNF
42 11.36 TNF IL6 IL1B
43 11.34 TNF IL6 IL1B CXCL8
44 11.27 TNF IL6 IL10 CXCL8
45 11.2 TNF IL6 IL1B IL1A IL10
46 11.15 IL6 IL1B IL10
47 11.1 TNF IL6 IL1B IL1A IL10 CXCL8
48 11.07 TNF IL6 CXCL8 CRP
49 11.06 TNF PGR IL1B ESR1
50 11.05 TNF IL6 IL1B IL1A IL10 GNRH1

GO Terms for Vaginal Discharge

Cellular components related to Vaginal Discharge according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 10.09 ALB CEACAM5 CRP CXCL8 GNRH1 HP
2 extracellular space GO:0005615 9.74 TNF SLPI OXT OBP2A IL6 IL1B

Biological processes related to Vaginal Discharge according to GeneCards Suite gene sharing:

(show all 36)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.51 TNF PGR OXT MAPK8IP1 IL6 IL1B
2 inflammatory response GO:0006954 10.41 TNF IL6 IL1B IL1A CXCL8 CRP
3 negative regulation of cell population proliferation GO:0008285 10.39 CXCL8 IL10 IL1A IL1B IL6 TNF
4 positive regulation of gene expression GO:0010628 10.39 CRP CXCL8 IL1A IL1B IL6 PGR
5 defense response to Gram-positive bacterium GO:0050830 10.26 TNF IL6 IL1B CRP
6 positive regulation of interleukin-6 production GO:0032755 10.22 TNF IL6 IL1B IL1A
7 positive regulation of JNK cascade GO:0046330 10.21 TNF MAPK8IP1 IL1B IL1A
8 acute-phase response GO:0006953 10.14 IL6 HP CRP
9 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 10.13 TNF IL1B IL1A
10 positive regulation of receptor signaling pathway via JAK-STAT GO:0046427 10.13 TNF IL6 IL10
11 positive regulation of interleukin-2 production GO:0032743 10.12 IL1B IL1A CD4
12 positive regulation of mitotic nuclear division GO:0045840 10.1 TNF IL1B IL1A
13 positive regulation of DNA-binding transcription factor activity GO:0051091 10.1 TNF IL6 IL1B IL10 ESR1
14 liver regeneration GO:0097421 10.09 TNF IL6 IL10
15 positive regulation of vascular endothelial growth factor production GO:0010575 10.08 IL1A IL1B IL6
16 response to glucocorticoid GO:0051384 10.08 TNF OXT IL6 IL10
17 positive regulation of cytokine production GO:0001819 10.07 IL10 IL1A IL1B TNF
18 negative regulation of neurogenesis GO:0050768 10.05 TNF IL6 IL1B
19 response to lipopolysaccharide GO:0032496 10.04 TNF SLPI IL1B IL1A IL10
20 regulation of sensory perception of pain GO:0051930 10.03 IL10 IL1A OXT
21 positive regulation of glial cell proliferation GO:0060252 9.99 TNF IL6 IL1B
22 negative regulation of cytokine production involved in immune response GO:0002719 9.97 TNF IL10
23 positive regulation of fever generation GO:0031622 9.97 TNF IL1B
24 response to activity GO:0014823 9.97 TNF OXT IL6 IL10
25 acute inflammatory response GO:0002526 9.96 TNF IL1A HP
26 sequestering of triglyceride GO:0030730 9.94 TNF IL1B
27 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.93 TNF IL1B IL10
28 positive regulation of prostaglandin secretion GO:0032308 9.91 IL1A IL1B OXT
29 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.89 TNF IL1B
30 fever generation GO:0001660 9.88 IL1B IL1A
31 chronic inflammatory response to antigenic stimulus GO:0002439 9.87 TNF IL10
32 positive regulation of neuroinflammatory response GO:0150078 9.8 TNF IL6 IL1B
33 negative regulation of lipid storage GO:0010888 9.73 CRP IL6 TNF
34 cellular response to lipopolysaccharide GO:0071222 9.7 TNF IL6 IL1B IL1A IL10 CXCL8
35 vascular endothelial growth factor production GO:0010573 9.63 TNF IL6 IL1B
36 immune response GO:0006955 9.4 TNF SLPI IL6 IL1B IL1A IL10

Molecular functions related to Vaginal Discharge according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.36 TNF IL6 IL1B IL1A IL10 CXCL8

Sources for Vaginal Discharge

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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