Aliases & Classifications for Vaginitis

MalaCards integrated aliases for Vaginitis:

Name: Vaginitis 12 43 44 15 73
Infective Vaginitis 73

Classifications:



Summaries for Vaginitis

MedlinePlus : 43 What is vaginitis? Vaginitis, also called vulvovaginitis, is an inflammation or infection of the vagina. It can also affect the vulva, which is the external part of a woman's genitals. Vaginitis can cause itching, pain, discharge, and odor. Vaginitis is common, especially in women in their reproductive years. It usually happens when there is a change in the balance of bacteria or yeast that are normally found in your vagina. There are different types of vaginitis, and they have different causes, symptoms, and treatments. What are the different causes of vaginitis? Bacterial vaginosis (BV) is the most common vaginal infection in women ages 15-44. It happens when there is an imbalance between the "good" and "harmful" bacteria that are normally found in a woman's vagina. Many things can change the balance of bacteria, including Taking antibiotics Douching Using an intrauterine device (IUD) Having unprotected sex with a new partner Having many sexual partners Yeast infections (candidiasis) happen when too much candida grows in the vagina. Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. You may have too much growing in the vagina because of Antibiotics Pregnancy Diabetes, especially if it is not well-controlled Corticosteroid medicines Trichomoniasis can also cause vaginitis. Trichomoniasis is a common sexually transmitted disease. It is caused by a parasite. You can also have vaginitis if you are allergic or sensitive to certain products that you use. Examples include vaginal sprays, douches, spermicides, soaps, detergents, or fabric softeners. They can cause burning, itching, and discharge. Hormonal changes can also cause vaginal irritation. Examples are when you are pregnant or breastfeeding, or when you have gone through menopause. Sometimes you can have more than one cause of vaginitis at the same time. What are the symptoms of vaginitis? The symptoms of vaginitis depend on which type you have. With BV, you may not have symptoms. You could have a thin white or gray vaginal discharge. There may be an odor, such as a strong fish-like odor, especially after sex. Yeast infections produce a thick, white discharge from the vagina that can look like cottage cheese. The discharge can be watery and often has no smell. Yeast infections usually cause the vagina and vulva to become itchy and red. You may not have symptoms when you have trichomoniasis. If you do have them, they include itching, burning, and soreness of the vagina and vulva. You may have burning during urination. You could also have gray-green discharge, which may smell bad. How is the cause of vaginitis diagnosed? To find out the cause of your symptoms, your health care provider may Ask you about your health history Do a pelvic exam Look for vaginal discharge, noting its color, qualities, and any odor Study a sample of your vaginal fluid under a microscope In some cases, you may need more tests. What are the treatments for vaginitis? The treatment depends on which type of vaginitis you have. BV is treatable with antibiotics. You may get pills to swallow, or cream or gel that you put in your vagina. During treatment, you should use a condom during sex or not have sex at all. Yeast infections are usually treated with a cream or with medicine that you put inside your vagina. You can buy over-the-counter treatments for yeast infections, but you need to be sure that you do have a yeast infection and not another type of vaginitis. See your health care provider if this is the first time you have had symptoms. Even if you have had yeast infections before, it is a good idea to call your health care provider before using an over-the-counter treatment. The treatment for trichomoniasis is usually a single-dose antibiotic. Both you and your partner(s) should be treated, to prevent spreading the infection to others and to keep from getting it again. If your vaginitis is due to an allergy or sensitivity to a product, you need to figure out which product is causing the problem. It could be a product that you started using recently. Once you figure it out, you should stop using the product. If the cause of your vaginitis is a hormonal change, your health care provider may give you estrogen cream to help with your symptoms. Can vaginitis cause other health problems? It is important to treat BV and trichomoniasis, because having either of them can increase your risk for getting HIV or another sexually transmitted disease. If you are pregnant, BV or trichomoniasis can increase your risk for preterm labor and preterm birth. How can I prevent vaginitis? To help prevent vaginitis Do not douche or use vaginal sprays Use a condom when having sex Avoid clothes that hold in heat and moisture Wear cotton underwear

MalaCards based summary : Vaginitis, also known as infective vaginitis, is related to postmenopausal atrophic vaginitis and chorioamnionitis, and has symptoms including leukorrhea, vaginal pruritus and vaginal odor. An important gene associated with Vaginitis is ESR1 (Estrogen Receptor 1), and among its related pathways/superpathways are Allograft rejection and Pathways in cancer. The drugs Desogestrel and Estradiol have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and uterus, and related phenotypes are cardiovascular system and growth/size/body region

Wikipedia : 76 Vaginitis is inflammation of the vagina. In most cases, it is a symptom of an infection of the... more...

Related Diseases for Vaginitis

Diseases related to Vaginitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 549)
# Related Disease Score Top Affiliating Genes
1 postmenopausal atrophic vaginitis 34.5 AR ESR1 ESR2
2 chorioamnionitis 31.6 CXCL8 IL1B IL6
3 chlamydia 31.6 CXCL8 IL1B IL6
4 bacterial vaginosis 30.5 CXCL8 DEFB4A IL1B IL6 PRF1
5 endometritis 30.4 ESR1 IL1B IL6
6 transsexualism 30.2 AR ESR2
7 vulvar vestibulitis syndrome 30.1 ESR1 IL1B
8 toxic shock syndrome 29.9 CXCL8 IL1B IL6
9 endometriosis 29.8 CXCL8 ESR1 ESR2 IL6
10 peritonitis 29.7 CXCL8 IL1B IL6
11 streptococcal toxic-shock syndrome 29.6 CXCL8 IL6
12 cervical incompetence 29.6 IL6 SERPINH1
13 prostatitis 29.5 CXCL8 IL1B IL6
14 preterm premature rupture of the membranes 29.4 CXCL8 IL6 SERPINH1
15 esophagitis 29.3 CXCL8 IL1B IL6
16 meningitis 29.2 CXCL8 IL1B IL6
17 bacteriuria 29.2 CXCL8 IL6 PRF1
18 crohn's disease 29.2 ABCB1 IL1B IL6
19 pneumonia 29.2 CXCL8 IL1B IL6
20 pyelonephritis 29.1 CXCL8 IL1B IL6
21 appendicitis 29.1 CXCL8 IL1B IL6
22 contact dermatitis 29.1 CXCL8 IL1B IL6
23 ulcerative colitis 28.7 ABCB1 CXCL8 IL1B IL6
24 colitis 28.7 ABCB1 CXCL8 IL1B IL6
25 vaginal disease 28.5 CXCL8 DEFB4A EZR IL1B IL6 PRF1
26 osteoporosis 28.4 AR ESR1 ESR2 IL1B IL6
27 uterine anomalies 28.3 CXCL8 ESR1 IL1B IL6 SERPINH1
28 gingivitis 28.2 CXCL8 DEFB4A IL1B IL6
29 placenta disease 28.0 CXCL8 IL1B IL6 SERPINH1
30 vaginal cancer 12.4
31 vaginal discharge 12.3
32 vaginal atresia 12.3
33 vaginal adenosarcoma 12.2
34 vaginal yolk sac tumor 12.0
35 vaginal squamous papilloma 12.0
36 vaginal spindle cell epithelioma 11.9
37 vaginal carcinosarcoma 11.9
38 transverse vaginal septum 11.9
39 longitudinal vaginal septum 11.9
40 uterus bicornis bicollis with partial vaginal septum and unilateral hematocolpos with ipsilateral renal agenesis 11.9
41 vaginal mullerian papilloma 11.8
42 vaginal adenoma 11.8
43 vaginal tubulovillous adenoma 11.8
44 vaginal benign neoplasm 11.8
45 vaginal glandular tumor 11.8
46 vaginal squamous tumor 11.8
47 vaginal endometrial stromal sarcoma 11.8
48 vaginal villous adenoma 11.8
49 vaginal tubular adenoma 11.8
50 vulvovaginitis 11.8

Graphical network of the top 20 diseases related to Vaginitis:



Diseases related to Vaginitis

Symptoms & Phenotypes for Vaginitis

UMLS symptoms related to Vaginitis:


leukorrhea, vaginal pruritus, vaginal odor, vaginal discomfort, vaginal pain or burning

MGI Mouse Phenotypes related to Vaginitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.13 PRF1 SERPINH1 SPTB AR IL1B ESR1
2 growth/size/body region MP:0005378 10.13 PRF1 SERPINH1 SPTB IL6 ABCB1 ESR2
3 hematopoietic system MP:0005397 10.1 PRF1 SH2D1A SPTB AR EZR IL1B
4 immune system MP:0005387 10.07 PRF1 SH2D1A SPTB AR EZR IL1B
5 digestive/alimentary MP:0005381 10 SERPINH1 ESR2 EZR AR ESR1 IL6
6 mortality/aging MP:0010768 9.96 PRF1 SERPINH1 SPTB IL6 ABCB1 ESR2
7 liver/biliary system MP:0005370 9.87 PRF1 SPTB AR ESR1 IL6 ABCB1
8 neoplasm MP:0002006 9.63 PRF1 IL6 ESR2 AR IL1B ESR1
9 nervous system MP:0003631 9.61 PRF1 SERPINH1 SPTB IL6 ABCB1 ESR2
10 reproductive system MP:0005389 9.17 PRF1 SPTB IL6 ABCB1 ESR2 AR

Drugs & Therapeutics for Vaginitis

Drugs for Vaginitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 196)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Desogestrel Approved Phase 4 54024-22-5 40973
2
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-28-2 5757
3 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 979-32-8
4
Ethinyl Estradiol Approved Phase 4,Phase 2 57-63-6 5991
5
Etonogestrel Approved, Investigational Phase 4 54048-10-1 40976 6917715
6
Polyestradiol phosphate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 28014-46-2
7
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
8
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable 443-48-1 4173
9
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable 18323-44-9 29029
10
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 22916-47-8 4189
11
Nystatin Approved, Vet_approved Phase 4,Phase 3 1400-61-9 11953884
12
Azithromycin Approved Phase 4,Phase 3,Not Applicable 83905-01-5 55185 447043
13
Fluconazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 86386-73-4 3365
14
Neomycin Approved, Vet_approved Phase 4,Phase 3 1404-04-2 8378
15
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
16
Clotrimazole Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 23593-75-1 2812
17
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
18
Tinidazole Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 19387-91-8 5479
19
Dequalinium Approved, Investigational Phase 4,Phase 3 6707-58-0
20
Terconazole Approved Phase 4,Phase 3,Early Phase 1,Not Applicable 67915-31-5 441383
21
Progesterone Approved, Vet_approved Phase 4,Phase 2 57-83-0 5994
22
Ephedrine Approved Phase 4,Phase 2,Phase 3 299-42-3 9294
23
Pseudoephedrine Approved Phase 4,Phase 2,Phase 3 90-82-4 7028
24
Norethindrone Approved Phase 4,Phase 2 68-22-4 6230
25 Cranberry Approved, Investigational, Nutraceutical Phase 4,Not Applicable
26 Apricot Approved, Nutraceutical Phase 4
27 Contraceptive Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
28 Contraceptives, Oral Phase 4,Phase 3,Phase 2
29 Estradiol 17 beta-cypionate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
30 Estradiol 3-benzoate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
31 Estrogens Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
33 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
34 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
35 Progestins Phase 4,Phase 2
36 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
37 Antibiotics, Antitubercular Phase 4,Phase 2,Not Applicable
38 Antidotes Phase 4
39 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable
40 Antioxidants Phase 4
41 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable
42 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable
43 Antiviral Agents Phase 4,Phase 2,Not Applicable
44 Expectorants Phase 4
45 N-monoacetylcystine Phase 4
46 Protective Agents Phase 4,Phase 2
47 Respiratory System Agents Phase 4,Phase 2,Phase 3
48 Clindamycin palmitate Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
49 Clindamycin phosphate Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
50 Antifungal Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 273)
# Name Status NCT ID Phase Drugs
1 Probiotics Capsule as Supplemental Therapy for Group B Streptococci Infection and Vaginitis During Pregnancy Unknown status NCT01779193 Phase 4
2 Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers Unknown status NCT01448291 Phase 4 Etonogestrel /Ethinyl Estradiol Contraceptive Vaginal Ring
3 Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4 N-Acetyl cysteine;Metronidazole + N-Acetyl cysteine;metronidazole
4 Probiotic Versus Placebo as Adjuvant for Bacterial Vaginosis Treatment During Pregnancy Unknown status NCT01558388 Phase 4 Lactobacillus acidophilus;Placebo
5 Open Study of the Efficacy of the Local Treatment With Polygynax of Bacterial and/or Mycotic Vaginitis Completed NCT02444481 Phase 4 Polygynax combinaison of polymyxin, Neomycin and Nystatin
6 Oral Low-molecular Weight Hyaluronic Acid in the Treatment of Atrophic Vaginitis Completed NCT02014428 Phase 4 Placebo
7 Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections Completed NCT01697826 Phase 4 ClinSupV3 -soft gelatin capsule;ClinSupV3ER- Extended release tablet
8 Vaginal Estrogens Comparative Trial on Pelvic Organ Prolapse Patients Completed NCT03032848 Phase 4 Conjugated Estrogen;Promestriene;Estriol;Vaginal Moisturizer - Cream
9 Periodical Presumptive Treatment for the Control of Gonococcal Infections Among Sex Workers Completed NCT01329588 Phase 4 Monthly antibiotic;Monthly placebo
10 Safety and Tolerability of Metronidazole Gel 1.3% Completed NCT02392026 Phase 4 Metronidazole Gel
11 Treatment of Bacterial Vaginosis Combined With Human Lactobacilli Completed NCT01245322 Phase 4 lactobacilli
12 Treatment of Bacterial Vaginosis (BV) With Tinidazole Completed NCT00334633 Phase 4 tinidazole, metronidazole
13 Treatment of Bacterial Vaginosis Completed NCT00324818 Phase 4 metronidazole and azithromycin
14 Lactoserum (Dermacyd Femina®) and Prevention of Recurrence of Bacterial Vaginosis Completed NCT00556179 Phase 4 Lactoserum (Dermacyd Femina®)
15 Prevention of Very Preterm Delivery by Testing for and Treatment of Bacterial Vaginosis Completed NCT00642980 Phase 4 Clindamycin;Placebo;Clindamycin
16 Clindamycin to Reduce Preterm Birth in a Low Resource Setting Completed NCT01800825 Phase 4 Clindamycin;Placebo
17 Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis Completed NCT02248506 Phase 4
18 Comparative Efficacy Study of 10 mg Dequalinium Chloride (Fluomizin) in the Treatment of Vulvovaginal Candidiasis Completed NCT02242695 Phase 4 Fluomizin vaginal tablets;Canesten vaginal tablets
19 Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasis Completed NCT02180828 Phase 4 Clotrimazole vaginal tablet;Fluconazole
20 Terconazole Vaginal Suppository vs Fluconazole for the Treatment of Severe Vulvovaginal Candidiasis Completed NCT02180100 Phase 4 Terconazole Vaginal Suppository;Fluconazole
21 Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina Completed NCT00194324 Phase 4 Miconazole nitrate
22 Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Study Completed NCT00464542 Phase 4 Metronidazole
23 Prevention of Preterm Birth in Pregnant Women at Risk Identified by Ultrasound: Evaluation of Two Treatment Strategies Completed NCT01643980 Phase 4 Vaginal micronized progesterone
24 Honghe Fujie Lotion for the Treatment of Bacterial Vaginosis Recruiting NCT03446443 Phase 4 Honghe Fujie lotion;Metronidazole Suppositories
25 Vaginal and Urinary Microbiome Trial Recruiting NCT02869165 Phase 4 Premarin vaginal cream;Apricot kernel oil
26 Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections Recruiting NCT02860845 Phase 4 Antibiotic (Clindamycin);Antifungal (Clotrimazole)
27 Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis Recruiting NCT02042287 Phase 4 Metronidazole
28 The Efficacy and Safety Study of Clindamycin Palmitate Hydrochloride Dispersible Tablet Treatment of Bacterial Vaginosis Recruiting NCT03080740 Phase 4 Clindamycin palmitate hydrochloride dispersible tablet;Metronidazole Tablet
29 The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis Recruiting NCT02905890 Phase 4 Norethisterone enantate
30 Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunity Recruiting NCT02432404 Phase 4 NuvaRing
31 Oral Metronidazole With Lactobacillus Vaginal Suppositories to Prevent Recurrence of Bacterial Vaginosis Recruiting NCT03099408 Phase 4 Metronidazole Oral;"Metronidazole" and "Lactobacillus"
32 Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity Active, not recruiting NCT02445989 Phase 4 NuvaRing
33 Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection Not yet recruiting NCT03532464 Phase 4 azithromycin;doxycycline
34 Colposeptine for the Treatment of Bacterial Vaginosis Terminated NCT01153958 Phase 4 Colposeptine;Metronidazole
35 Saginil in vs. Placebo for Gynecologic Oncology Patients Affected by Vaginitis Unknown status NCT01420510 Phase 2, Phase 3 Adelmidrol vaginal gel;Placebo vaginal gel
36 Safety and Efficacy Study of Gynevac Lactobacillus Vaccine in the Treatment of Bacterial Vaginosis Unknown status NCT02173184 Phase 3
37 A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosis Unknown status NCT01089348 Phase 2, Phase 3 Lactofiltrum + Metronidazole;Metronidazole
38 Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infections Unknown status NCT02186145 Phase 3 Association of metronidazole; nystatin and dexamethasone;Flagyl
39 Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis Unknown status NCT00889356 Phase 3 Clindamycin 100mg and Ketoconazole 400mg;Tetracycline 100mg and Amphotericin B 50mg
40 Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery Unknown status NCT00491270 Phase 3
41 Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery Unknown status NCT01152528 Phase 3
42 The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients Unknown status NCT00536848 Phase 2, Phase 3 Metronidazole
43 Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community Unknown status NCT00124878 Phase 3
44 Performance Proof of Product Developed to Detect Abnormal Vaginal pH Unknown status NCT01542606 Phase 3
45 Assessment of the Efficacy of POLYGYNAX® in the Empirical Treatment of Infectious Vaginitis Completed NCT02515656 Phase 3 POLYGYNAX®;GYNODAKTARIN®;Placebo
46 Study Evaluating Conjugated Estrogen Cream for Atrophic Vaginitis Completed NCT00137371 Phase 3 PVC (daily for 21 days, 7 days off);PVC (twice weekly)
47 Study to Evaluate Equivalence of Estradiol Vaginal Cream 0.01% to Estrace® Cream 0.01% in Atrophic Vaginitis Completed NCT03294538 Phase 3 Estrace® Cream;Generic Estradiol Cream;Vehicle Cream
48 A Study to Compare Efficacy and Safety of an Ovule Containing Terconazole, Clindamycin and Fluocinolone Versus an Ovule Containing Metronidazole, Nystatin and Fluocinolone in the Treatment of Secondary Vulvar/ or Vaginal Symptoms of Infectious Vaginitis/ Completed NCT01867164 Phase 3 Gynoclin V;Vagitrol V
49 A Multi-Site Study Comparing Estradiol Vaginal Cream (0.01%) to Estrace® Cream (0.01%) in Postmenopausal Females With Atrophic Vaginitis Completed NCT02995694 Phase 3 Estradiol;Placebos;Reference
50 A Comparison of Estradiol Vaginal Cream to Estrace® Cream in 350 Postmenopausal Females With Atrophic Vaginitis Completed NCT02195986 Phase 3 Estradiol Vaginal Cream, 0.01%;Estrace® 0.01% cream;Placebo Vaginal Cream

Search NIH Clinical Center for Vaginitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: vaginitis

Genetic Tests for Vaginitis

Anatomical Context for Vaginitis

MalaCards organs/tissues related to Vaginitis:

41
Testes, Colon, Uterus, Cervix, Placenta, Bone, Neutrophil

Publications for Vaginitis

Articles related to Vaginitis:

(show top 50) (show all 2833)
# Title Authors Year
1
Application of SIS (saline infusion sonohysterography) in diagnosis of perforated transverse vaginal septum. ( 29458895 )
2018
2
Comparison of Uphold<sup>TM</sup> Vaginal Mesh Procedure with Hysterectomy or Uterine Preservation for the Treatment of Pelvic Organ Prolapse. ( 29930249 )
2018
3
CXCL17 Chemokine-Dependent Mobilization of CXCR8<sup>+</sup>CD8<sup>+</sup> Effector Memory and Tissue-Resident Memory T Cells in the Vaginal Mucosa Is Associated with Protection against Genital Herpes. ( 29549178 )
2018
4
Risk of major congenital malformations following first-trimester exposure to vaginal azoles used for treating vulvovaginal candidiasis: a population-based retrospective cohort study. ( 29790255 )
2018
5
The effect of vaginal microbial communities on colonization by Staphylococcus aureus with the gene for toxic shock syndrome toxin 1 (TSST-1): a case-control study. ( 29762733 )
2018
6
Novel management of vaginal chronic graft-versus-host disease causing haematometra and haematocolpos. ( 29705733 )
2018
7
Predictors for dislodgment of vaginal pessary within one year in women with pelvic organ prolapse. ( 29290215 )
2018
8
Retinal vein occlusion associated with combined hormonal contraceptive vaginal ring use. ( 29862193 )
2018
9
Vulvo-vaginal lichen planus: A focussed review for the clinician. ( 29961956 )
2018
10
Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis. ( 29632854 )
2018
11
Vaginal bleeding and a giant ovarian cyst in an infant with 21-hydroxylase deficiency. ( 29252197 )
2018
12
Are previous episodes of bacterial vaginosis a predictor for vaginal symptoms in breast cancer patients treated with aromatase inhibitors? ( 29409388 )
2018
13
Metatranscriptome Analysis of the Vaginal Microbiota Reveals Potential Mechanisms for Protection against Metronidazole in Bacterial Vaginosis. ( 29875146 )
2018
14
Inguinal Hyperhidrosis: Case Report of an Uncommon Cause of Vaginitis. ( 29421341 )
2018
15
A Long-Standing Primary Vaginal Paraganglioma-Coexisting with Esophageal Carcinoma. ( 29887722 )
2018
16
Prevention practices of vaginitis among Malaysian women and its associated factors. ( 29526143 )
2018
17
Comparison of Postoperative Short-Term Outcomes between Tension-Free Vaginal Mesh Surgery Using the Capioa8c SLIM Suture Capturing Device and Conventional TVM Surgery for Pelvic Organ Prolapse. ( 29805449 )
2018
18
Microbial Culturomics Broadens Human Vaginal Flora Diversity: Genome Sequence and Description of Prevotella lascolaii sp. nov. Isolated from a Patient with Bacterial Vaginosis. ( 29447068 )
2018
19
Total Colpectomy Increases the Risk of Postoperative Hydronephrosis in Vaginal Cancer Patients. ( 29469636 )
2018
20
Blood transfusion after vaginal hysterectomy for pelvic organ prolapse. ( 29872988 )
2018
21
Clinical Predictors of Successful Vaginal Myomectomy for Prolapsed Pedunculated Uterine Leiomyoma. ( 29449196 )
2018
22
Can surgical reconstruction of vaginal and ligamentous laxity cure over active bladder symptoms in women with pelvic organ prolapse? ( 29908047 )
2018
23
Is non-response to fluconazole maintenance therapy for recurrent Candida vaginitis related to sensitization to atopic reactions? ( 29469170 )
2018
24
Abnormal vaginal microbioma is associated with severity of localized provoked vulvodynia. Role of aerobic vaginitis and Candida in the pathogenesis of vulvodynia. ( 29934834 )
2018
25
Crimean-Congo hemorrhagic fever with hepatic impairment and vaginal hemorrhage: a case report. ( 29724249 )
2018
26
Correction to: Association between vaginal bulge and anatomical pelvic organ prolapse during pregnancy and postpartum: an observational study. ( 29356859 )
2018
27
Saccharomyces cerevisiae-based probiotic as novel anti-fungal and anti-inflammatory agent for therapy of vaginal candidiasis. ( 29380641 )
2018
28
Magnetic resonance imaging of vaginal support structure before and after Vecchietti procedure in women with Mayer-Rokitansky-KA1ster-Hauser syndrome. ( 29603118 )
2018
29
The effect of a vaginal suppository formulation of dill (Anethum graveolens) in comparison to clotrimazole vaginal tablet on the treatment of vulvovaginal candidiasis. ( 29553834 )
2018
30
Synchronous, but separate, bladder and vaginal rhabdomyosarcoma: a novel genetic case report. ( 29900825 )
2018
31
Antifungal activity of essential oils against azole-resistant and azole-susceptible vaginal Candida glabrata strains. ( 29746162 )
2018
32
Functioning left uterine horn with cervico-vaginal atresia and ovarian maldescent - an unclassified MA1llerian anomaly treated with horn-vaginal anastomosis. ( 29553867 )
2018
33
Quality of life following vaginal reconstructive versus obliterative surgery for treating advanced pelvic organ prolapse. ( 29379997 )
2018
34
Tetraglochin cristatum (Britton) Roth: a medicinal plant from the Argentinean highlands with potential use in vaginal candidiasis. ( 29307753 )
2018
35
Vaginal atresia and cervical agenesis combined with asymmetric septate uterus: A case report of a new genital malformation and literature review. ( 29505013 )
2018
36
Vaginal leiomyoma in a chinchilla (Chinchilla Laniger). ( 29964294 )
2018
37
Vaginal Discharge in a Pre-pubertal Girl Posing a Diagnostic Challenge. ( 29872604 )
2018
38
Response of lactating dairy cows with or without purulent vaginal discharge to gonadotropin-releasing hormone and prostaglandin F2I+. ( 29385599 )
2018
39
Diagnostic Performance of a Molecular Test versus Clinician Assessment of Vaginitis. ( 29643195 )
2018
40
The Etiology of Vaginal Discharge Syndrome in Zimbabwe: Results from the Zimbabwe STI Etiology Study. ( 29465674 )
2018
41
A Rare Case of Pediatric Vaginal Yolk Sac Tumor. ( 29548872 )
2018
42
Iron restriction to clinical isolates of <i>Candida albicans</i> by the novel chelator DIBI inhibits growth and increases sensitivity to azoles <i>in vitro</i> and <i>in vivo</i> in a murine model of experimental vaginitis. ( 29844048 )
2018
43
Chlorhexidine vaginal preparation versus standard treatment at caesarean section to reduce endometritis and prevent sepsis-a feasibility study protocol (the PREPS trial). ( 29881638 )
2018
44
Proanthocyanidin polymeric tannins from Stryphnodendron adstringens are effective against Candida spp. isolates and for vaginal candidiasis treatment. ( 29325916 )
2018
45
Candida vaginitis: virulence, host response and vaccine prospects. ( 29538739 )
2018
46
Combined laparoscopic and vaginal cervicovaginal reconstruction using acellular porcine small intestinal submucosa (SIS) graft in a patient with Mayer-Rokitansky-KA1ster-Hauser syndrome (U5aC4V4). ( 29890355 )
2018
47
The Effect of Prangos Ferulacea Vaginal Cream on Accelerating the Recovery of Bacterial Vaginosis: A Randomized Controlled Clinical Trial. ( 29607339 )
2018
48
<i>'Lactobacillus raoultii'</i> sp. nov., a new bacterium isolated from the vaginal flora of a woman with bacterial vaginosis. ( 29204281 )
2018
49
Implementation of vaginal cleansing prior to cesarean delivery to decrease endometritis rates. ( 29343134 )
2018
50
Vaginitis. ( 29671518 )
2018

Variations for Vaginitis

Expression for Vaginitis

Search GEO for disease gene expression data for Vaginitis.

Pathways for Vaginitis

Pathways related to Vaginitis according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.7 ABCB1 CXCL8 IL1B IL6 PRF1
2 12.61 AR CXCL8 ESR1 ESR2 IL6
3
Show member pathways
12.07 CXCL8 DEFB4A IL1B IL6
4
Show member pathways
11.96 AR EZR IL6
5 11.86 CXCL8 IL1B IL6
6 11.83 CXCL8 IL1B IL6
7 11.79 CXCL8 IL1B IL6
8 11.76 CXCL8 IL1B IL6
9 11.73 CXCL8 IL1B IL6
10 11.73 AR ESR1 ESR2
11
Show member pathways
11.68 AR ESR1 ESR2
12 11.67 CXCL8 IL1B IL6
13 11.63 CXCL8 IL1B IL6
14 11.57 CXCL8 IL1B IL6
15
Show member pathways
11.47 CXCL8 DEFB4A IL1B IL6
16 11.45 CXCL8 IL1B IL6
17
Show member pathways
11.43 CXCL8 IL1B IL6
18 11.32 CXCL8 IL1B IL6
19 11.23 CXCL8 IL1B IL6
20 11.23 AR CXCL8 ESR2 IL1B IL6
21 11.19 CXCL8 IL1B IL6
22 10.99 AR IL1B IL6
23 10.98 ESR1 ESR2
24 10.89 CXCL8 IL6
25 9.86 ESR1 ESR2

GO Terms for Vaginitis

Biological processes related to Vaginitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.76 AR CXCL8 IL1B IL6
2 positive regulation of gene expression GO:0010628 9.67 AR EZR IL1B IL6
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.58 AR IL1B IL6
4 cell-cell signaling GO:0007267 9.56 AR ESR2 IL1B SH2D1A
5 positive regulation of transcription, DNA-templated GO:0045893 9.55 AR ESR1 ESR2 IL1B IL6
6 positive regulation of leukocyte chemotaxis GO:0002690 9.48 CXCL8 IL6
7 intracellular estrogen receptor signaling pathway GO:0030520 9.43 ESR1 ESR2
8 mammary gland alveolus development GO:0060749 9.32 AR ESR1
9 steroid hormone mediated signaling pathway GO:0043401 9.13 AR ESR1 ESR2
10 positive regulation of DNA binding transcription factor activity GO:0051091 8.92 ESR1 ESR2 IL1B IL6

Molecular functions related to Vaginitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase binding GO:0051117 9.58 AR ESR1 EZR
2 steroid hormone receptor activity GO:0003707 9.54 AR ESR1 ESR2
3 nuclear receptor activity GO:0004879 9.33 AR ESR1 ESR2
4 estrogen receptor activity GO:0030284 9.32 ESR1 ESR2
5 estrogen response element binding GO:0034056 9.26 ESR1 ESR2
6 steroid binding GO:0005496 9.13 AR ESR1 ESR2
7 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding GO:0038052 8.62 ESR1 ESR2
8 protein binding GO:0005515 10.25 ABCB1 AR CXCL8 DEFB4A DLAT ESR1

Sources for Vaginitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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