Aliases & Classifications for Vaginitis

MalaCards integrated aliases for Vaginitis:

Name: Vaginitis 12 44 45 15 74
Infective Vaginitis 74


External Ids:

Disease Ontology 12 DOID:2170
ICD9CM 36 616.1 616.10
MeSH 45 D014627
NCIt 51 C26911
SNOMED-CT 69 30800001

Summaries for Vaginitis

MedlinePlus : 44 What is vaginitis? Vaginitis, also called vulvovaginitis, is an inflammation or infection of the vagina. It can also affect the vulva, which is the external part of a woman's genitals. Vaginitis can cause itching, pain, discharge, and odor. Vaginitis is common, especially in women in their reproductive years. It usually happens when there is a change in the balance of bacteria or yeast that are normally found in your vagina. There are different types of vaginitis, and they have different causes, symptoms, and treatments. What causes vaginitis? Bacterial vaginosis (BV) is the most common vaginal infection in women ages 15-44. It happens when there is an imbalance between the "good" and "harmful" bacteria that are normally found in a woman's vagina. Many things can change the balance of bacteria, including Taking antibiotics Douching Using an intrauterine device (IUD) Having unprotected sex with a new partner Having many sexual partners Yeast infections (candidiasis) happen when too much candida grows in the vagina. Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. You may have too much growing in the vagina because of Antibiotics Pregnancy Diabetes, especially if it is not well-controlled Corticosteroid medicines Trichomoniasis can also cause vaginitis. Trichomoniasis is a common sexually transmitted disease. It is caused by a parasite. You can also have vaginitis if you are allergic or sensitive to certain products that you use. Examples include vaginal sprays, douches, spermicides, soaps, detergents, or fabric softeners. They can cause burning, itching, and discharge. Hormonal changes can also cause vaginal irritation. Examples are when you are pregnant or breastfeeding, or when you have gone through menopause. Sometimes you can have more than one cause of vaginitis at the same time. What are the symptoms of vaginitis? The symptoms of vaginitis depend on which type you have. With BV, you may not have symptoms. You could have a thin white or gray vaginal discharge. There may be an odor, such as a strong fish-like odor, especially after sex. Yeast infections produce a thick, white discharge from the vagina that can look like cottage cheese. The discharge can be watery and often has no smell. Yeast infections usually cause the vagina and vulva to become itchy and red. You may not have symptoms when you have trichomoniasis. If you do have them, they include itching, burning, and soreness of the vagina and vulva. You may have burning during urination. You could also have gray-green discharge, which may smell bad. How is the cause of vaginitis diagnosed? To find out the cause of your symptoms, your health care provider may Ask you about your medical history Do a pelvic exam Look for vaginal discharge, noting its color, qualities, and any odor Study a sample of your vaginal fluid under a microscope In some cases, you may need more tests. What are the treatments for vaginitis? The treatment depends on which type of vaginitis you have. BV is treatable with antibiotics. You may get pills to swallow, or cream or gel that you put in your vagina. During treatment, you should use a condom during sex or not have sex at all. Yeast infections are usually treated with a cream or with medicine that you put inside your vagina. You can buy over-the-counter treatments for yeast infections, but you need to be sure that you do have a yeast infection and not another type of vaginitis. See your health care provider if this is the first time you have had symptoms. Even if you have had yeast infections before, it is a good idea to call your health care provider before using an over-the-counter treatment. The treatment for trichomoniasis is usually a single-dose antibiotic. Both you and your partner(s) should be treated, to prevent spreading the infection to others and to keep from getting it again. If your vaginitis is due to an allergy or sensitivity to a product, you need to figure out which product is causing the problem. It could be a product that you started using recently. Once you figure it out, you should stop using the product. If the cause of your vaginitis is a hormonal change, your health care provider may give you estrogen cream to help with your symptoms. Can vaginitis cause other health problems? It is important to treat BV and trichomoniasis, because having either of them can increase your risk for getting HIV or another sexually transmitted disease. If you are pregnant, BV or trichomoniasis can increase your risk for preterm labor and preterm birth. Can vaginitis be prevented? To help prevent vaginitis Do not douche or use vaginal sprays Use a condom when having sex Avoid clothes that hold in heat and moisture Wear cotton underwear

MalaCards based summary : Vaginitis, also known as infective vaginitis, is related to postmenopausal atrophic vaginitis and trichomoniasis, and has symptoms including leukorrhea, vaginal pruritus and vaginal odor. An important gene associated with Vaginitis is ESR1 (Estrogen Receptor 1), and among its related pathways/superpathways are Pathways in cancer and IL-17 Family Signaling Pathways. The drugs Cranberry and Apricot have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and cervix, and related phenotypes are cardiovascular system and growth/size/body region

Disease Ontology : 12 A vaginal disease that is characterized by inflammation of the vagina.

Wikipedia : 77 Vaginitis, also known as vulvovaginitis, is inflammation of the vagina and vulva. Symptoms may include... more...

Related Diseases for Vaginitis

Diseases related to Vaginitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 785)
# Related Disease Score Top Affiliating Genes
1 postmenopausal atrophic vaginitis 34.4 AR ESR1 ESR2
2 trichomoniasis 32.6 CXCL8 LAP3
3 endometritis 32.0 ESR1 IL1B IL6
4 chlamydia 31.9 CXCL8 IL1B IL6
5 chorioamnionitis 31.9 CXCL8 IL1B IL6
6 vaginal disease 31.7 CXCL8 DEFB4A EZR IL1B IL6 LAP3
7 bacterial vaginosis 31.5 CXCL8 DEFB4A IL1B IL6 LAP3
8 female reproductive system disease 31.4 CXCL8 ESR1 ESR2 IL6
9 cervicitis 30.4 CXCL8 DEFB4A
10 toxic shock syndrome 30.4 CXCL8 IL1B IL6
11 peritonitis 30.1 CXCL8 IL1B IL6
12 endometriosis 30.0 CXCL8 ESR1 ESR2 IL1B IL6
13 vulvar vestibulitis syndrome 30.0 ESR1 IL1B
14 estrogen excess 29.8 ESR1 ESR2
15 haemophilus influenzae 29.8 CXCL8 IL1B
16 endometrial stromal sarcoma 29.8 CXCL8 ESR1 IL6
17 meningitis 29.7 CXCL8 IL1B IL6
18 preterm premature rupture of the membranes 29.7 CXCL8 IL1B IL6 SPTB
19 colitis 29.6 ABCB1 CXCL8 IL1B IL6
20 endometrial disease 29.6 CXCL8 ESR1 IL1B IL6
21 streptococcal toxic-shock syndrome 29.5 CXCL8 IL6
22 crohn's colitis 29.5 CXCL8 IL1B
23 pyelonephritis 29.5 CXCL8 IL1B IL6
24 pneumonia 29.5 CXCL8 IL1B IL6
25 placenta disease 29.5 CXCL8 IL1B IL6
26 ulcerative colitis 29.4 ABCB1 CXCL8 IL1B IL6
27 prostatitis 29.3 CXCL8 IL1B IL6
28 leptospirosis 29.3 CXCL8 IL1B IL6
29 appendicitis 29.3 CXCL8 IL1B IL6
30 bacterial meningitis 29.3 CXCL8 IL1B IL6
31 contact dermatitis 29.3 CXCL8 IL1B IL6
32 osteomyelitis 29.3 CXCL8 IL1B IL6
33 osteoporosis 29.2 AR ESR1 ESR2 IL1B IL6
34 behcet syndrome 29.1 CXCL8 IL1B IL6
35 inflammatory bowel disease 29.1 ABCB1 CXCL8 IL1B IL6
36 bacterial infectious disease 29.0 CXCL8 DEFB4A IL1B IL6
37 gingivitis 28.8 CXCL8 DEFB4A IL1B IL6
38 vaginal cancer 12.6
39 vaginal discharge 12.5
40 vaginal atresia 12.4
41 vaginal yolk sac tumor 12.4
42 vaginal adenosarcoma 12.4
43 vaginal carcinosarcoma 12.3
44 vaginal spindle cell epithelioma 12.3
45 vaginal mullerian papilloma 12.2
46 vaginal adenoma 12.2
47 vaginal tubulovillous adenoma 12.2
48 vaginal glandular tumor 12.2
49 vaginal squamous papilloma 12.2
50 vaginal squamous tumor 12.2

Graphical network of the top 20 diseases related to Vaginitis:

Diseases related to Vaginitis

Symptoms & Phenotypes for Vaginitis

UMLS symptoms related to Vaginitis:

leukorrhea, vaginal pruritus, vaginal odor, vaginal discomfort, vaginal pain or burning

MGI Mouse Phenotypes related to Vaginitis:

# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.03 ABCB1 AR ESR1 ESR2 FN1 IL1B
2 growth/size/body region MP:0005378 10.02 ABCB1 AR ESR1 ESR2 EZR FN1
3 hematopoietic system MP:0005397 10.02 ABCB1 AR ESR1 ESR2 EZR FN1
4 immune system MP:0005387 10 ABCB1 AR ESR1 ESR2 EZR FN1
5 digestive/alimentary MP:0005381 9.88 ABCB1 AR ESR1 ESR2 EZR IL6
6 liver/biliary system MP:0005370 9.7 ABCB1 AR ESR1 ESR2 FN1 IL6
7 neoplasm MP:0002006 9.43 AR ESR1 ESR2 FN1 IL1B IL6
8 reproductive system MP:0005389 9.17 ABCB1 AR ESR1 ESR2 FN1 IL6

Drugs & Therapeutics for Vaginitis

Drugs for Vaginitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 213)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Cranberry Approved, Investigational Phase 4,Not Applicable
2 Apricot Approved Phase 4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 22916-47-8 4189
Clotrimazole Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 23593-75-1 2812
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable 18323-44-9 29029
Ethinyl Estradiol Approved Phase 4,Phase 2 57-63-6 5991
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-28-2 5757
Etonogestrel Approved, Investigational Phase 4 54048-10-1 6917715 40976
Polyestradiol phosphate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 28014-46-2
Desogestrel Approved Phase 4 54024-22-5 40973
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable 443-48-1 4173
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
Nystatin Approved, Vet_approved Phase 4,Phase 3 1400-61-9 11953884
Azithromycin Approved Phase 4,Phase 3,Not Applicable 83905-01-5 447043 55185
Fluconazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 86386-73-4 3365
Neomycin Approved, Vet_approved Phase 4,Phase 3 1404-04-2 8378
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
Tinidazole Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 19387-91-8 5479
Dequalinium Approved, Investigational Phase 4,Phase 3 6707-58-0
Terconazole Approved Phase 4,Phase 3,Early Phase 1,Not Applicable 67915-31-5 441383
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 57-83-0 5994
Secnidazole Approved Phase 4,Phase 3 3366-95-8
Norethindrone Approved Phase 4,Phase 2 68-22-4 6230
Lidocaine Approved, Vet_approved Phase 4,Phase 2 137-58-6 3676
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
Chlorquinaldol Approved Phase 4 72-80-0
Norethindrone enanthate Experimental Phase 4 3836-23-5
29 Acidophilus Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
30 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
31 Estrogens Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
33 Estrogens, Conjugated (USP) Phase 4,Phase 3,Phase 1,Not Applicable
34 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
35 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
36 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 1,Not Applicable
37 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
38 Clindamycin palmitate Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
39 Steroid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
40 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
41 Antitubercular Agents Phase 4,Not Applicable
42 Antifungal Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
43 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable
44 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable
45 Clindamycin phosphate Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
46 Estradiol 17 beta-cypionate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
47 Contraceptive Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
48 Contraceptives, Oral Phase 4,Phase 3,Phase 2
49 Estradiol 3-benzoate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Progestins Phase 4,Phase 3,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 303)
# Name Status NCT ID Phase Drugs
1 Probiotics Capsule as Supplemental Therapy for Group B Streptococci Infection and Vaginitis During Pregnancy Unknown status NCT01779193 Phase 4
2 Vaginal and Urinary Microbiome Trial Unknown status NCT02869165 Phase 4 Premarin vaginal cream;Apricot kernel oil
3 Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections Unknown status NCT02860845 Phase 4 Antibiotic (Clindamycin);Antifungal (Clotrimazole)
4 Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers Unknown status NCT01448291 Phase 4 Etonogestrel /Ethinyl Estradiol Contraceptive Vaginal Ring
5 The Efficacy and Safety Study of Clindamycin Palmitate Hydrochloride Dispersible Tablet Treatment of Bacterial Vaginosis Unknown status NCT03080740 Phase 4 Clindamycin palmitate hydrochloride dispersible tablet;Metronidazole Tablet
6 Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4 N-Acetyl cysteine;Metronidazole + N-Acetyl cysteine;metronidazole
7 Probiotic Versus Placebo as Adjuvant for Bacterial Vaginosis Treatment During Pregnancy Unknown status NCT01558388 Phase 4 Lactobacillus acidophilus;Placebo
8 Open Study of the Efficacy of the Local Treatment With Polygynax of Bacterial and/or Mycotic Vaginitis Completed NCT02444481 Phase 4 Polygynax combinaison of polymyxin, Neomycin and Nystatin
9 Oral Low-molecular Weight Hyaluronic Acid in the Treatment of Atrophic Vaginitis Completed NCT02014428 Phase 4 Placebo
10 Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections Completed NCT01697826 Phase 4 ClinSupV3 -soft gelatin capsule;ClinSupV3ER- Extended release tablet
11 Vaginal Estrogens Comparative Trial on Pelvic Organ Prolapse Patients Completed NCT03032848 Phase 4 Conjugated Estrogen;Promestriene;Estriol;Vaginal Moisturizer - Cream
12 Periodical Presumptive Treatment for the Control of Gonococcal Infections Among Sex Workers Completed NCT01329588 Phase 4 Monthly antibiotic;Monthly placebo
13 Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity Completed NCT02445989 Phase 4 NuvaRing
14 Safety and Tolerability of Metronidazole Gel 1.3% Completed NCT02392026 Phase 4 Metronidazole Gel
15 Treatment of Bacterial Vaginosis Combined With Human Lactobacilli Completed NCT01245322 Phase 4 lactobacilli
16 Treatment of Bacterial Vaginosis (BV) With Tinidazole Completed NCT00334633 Phase 4 tinidazole, metronidazole
17 Treatment of Bacterial Vaginosis Completed NCT00324818 Phase 4 metronidazole and azithromycin
18 Lactoserum (Dermacyd Femina®) and Prevention of Recurrence of Bacterial Vaginosis Completed NCT00556179 Phase 4 Lactoserum (Dermacyd Femina®)
19 Prevention of Very Preterm Delivery by Testing for and Treatment of Bacterial Vaginosis Completed NCT00642980 Phase 4 Clindamycin;Placebo;Clindamycin
20 Clindamycin to Reduce Preterm Birth in a Low Resource Setting Completed NCT01800825 Phase 4 Clindamycin;Placebo
21 Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis Completed NCT02248506 Phase 4
22 Comparative Efficacy Study of 10 mg Dequalinium Chloride (Fluomizin) in the Treatment of Vulvovaginal Candidiasis Completed NCT02242695 Phase 4 Fluomizin vaginal tablets;Canesten vaginal tablets
23 Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasis Completed NCT02180828 Phase 4 Clotrimazole vaginal tablet;Fluconazole
24 Terconazole Vaginal Suppository vs Fluconazole for the Treatment of Severe Vulvovaginal Candidiasis Completed NCT02180100 Phase 4 Terconazole Vaginal Suppository;Fluconazole
25 Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina Completed NCT00194324 Phase 4 Miconazole nitrate
26 Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Study Completed NCT00464542 Phase 4 Metronidazole
27 Prevention of Preterm Birth in Pregnant Women at Risk Identified by Ultrasound: Evaluation of Two Treatment Strategies Completed NCT01643980 Phase 4 Vaginal micronized progesterone
28 Honghe Fujie Lotion for the Treatment of Bacterial Vaginosis Recruiting NCT03446443 Phase 4 Honghe Fujie lotion;Metronidazole Suppositories
29 Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis Recruiting NCT02042287 Phase 4 Metronidazole
30 Postmenopausal Pessary Users: Estrogen Versus Trimosan Recruiting NCT03943823 Phase 4 Estrogen vaginal cream;Trimo-San vaginal gel
31 Evaluate the Safety of a Single Oral Dose of Solosec™ (Secnidazole) 2g for the Treatment of Adolescent Girls With BV Recruiting NCT03937869 Phase 4 Secnidazole
32 Probiotics as Adjuvant Treatment for Bacterial Vaginosis Recruiting NCT03894813 Phase 4 "Probiotics" and "Metronidazole";Metronidazole Vaginal
33 The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis Recruiting NCT02905890 Phase 4 Norethisterone enantate
34 Oral Metronidazole With Lactobacillus Vaginal Suppositories to Prevent Recurrence of Bacterial Vaginosis Recruiting NCT03099408 Phase 4 Metronidazole Oral;"Metronidazole" and "Lactobacillus"
35 Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunity Active, not recruiting NCT02432404 Phase 4 NuvaRing
36 Evaluation of Efficacy and Safety of Gynomax® XL Ovule Not yet recruiting NCT03839875 Phase 4 Gynomax® XL Vaginal Ovule
37 Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection Not yet recruiting NCT03532464 Phase 4 azithromycin;doxycycline
38 Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse Not yet recruiting NCT03939715 Phase 4
39 Colposeptine for the Treatment of Bacterial Vaginosis Terminated NCT01153958 Phase 4 Colposeptine;Metronidazole
40 Saginil in vs. Placebo for Gynecologic Oncology Patients Affected by Vaginitis Unknown status NCT01420510 Phase 2, Phase 3 Adelmidrol vaginal gel;Placebo vaginal gel
41 Safety and Efficacy Study of Gynevac Lactobacillus Vaccine in the Treatment of Bacterial Vaginosis Unknown status NCT02173184 Phase 3
42 A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosis Unknown status NCT01089348 Phase 2, Phase 3 Lactofiltrum + Metronidazole;Metronidazole
43 Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infections Unknown status NCT02186145 Phase 3 Association of metronidazole; nystatin and dexamethasone;Flagyl
44 Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis Unknown status NCT00889356 Phase 3 Clindamycin 100mg and Ketoconazole 400mg;Tetracycline 100mg and Amphotericin B 50mg
45 Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery Unknown status NCT00491270 Phase 3
46 Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery Unknown status NCT01152528 Phase 3
47 The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients Unknown status NCT00536848 Phase 2, Phase 3 Metronidazole
48 Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community Unknown status NCT00124878 Phase 3
49 Performance Proof of Product Developed to Detect Abnormal Vaginal pH Unknown status NCT01542606 Phase 3
50 Assessment of the Efficacy of POLYGYNAX® in the Empirical Treatment of Infectious Vaginitis Completed NCT02515656 Phase 3 POLYGYNAX®;GYNODAKTARIN®;Placebo

Search NIH Clinical Center for Vaginitis

Inferred drug relations via UMLS 74 / NDF-RT 52 :

Cochrane evidence based reviews: vaginitis

Genetic Tests for Vaginitis

Anatomical Context for Vaginitis

MalaCards organs/tissues related to Vaginitis:

Testes, Colon, Cervix, Ovary, Uterus, T Cells, Kidney

Publications for Vaginitis

Articles related to Vaginitis:

(show top 50) (show all 1229)
# Title Authors Year
Vaginitis, Coronary Artery Disease, Hypertension in Children, COPD, Alzheimer Disease. ( 31038905 )
Bacterial Vaginosis and Desquamative Inflammatory Vaginitis. ( 30865815 )
Bacterial Vaginosis and Desquamative Inflammatory Vaginitis. Reply. ( 30865816 )
The antiviral activity of arbidol hydrochloride against herpes simplex virus type II (HSV-2) in a mouse model of vaginitis. ( 30612085 )
Plasma cell vulvitis presenting as postmenopausal atrophic vaginitis - a case report. ( 31018733 )
Molecular-based Testing for Sexually Transmitted Infections Using Samples Previously Collected for Vaginitis Diagnosis. ( 30084883 )
Calophyllum inophyllum in vaginitis treatment: Stimulated by electroporation with an in vitro approach. ( 30465335 )
Aerobic vaginitis in late pregnancy and outcomes of pregnancy. ( 30467614 )
Accuracy of the BD MAX™ vaginal panel in the diagnosis of infectious vaginitis. ( 30685805 )
Erratum for Savage et al., "Iron Restriction to Clinical Isolates of Candida albicans by the Novel Chelator DIBI Inhibits Growth and Increases Sensitivity to Azoles In Vitro and In Vivo in a Murine Model of Experimental Vaginitis". ( 30696693 )
PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis. ( 30792037 )
Comparison of the effect of hyaluronic acid and estrogen on atrophic vaginitis in menopausal women: A systematic review. ( 30798700 )
Case Report: Efficient and Cost-Effective Diagnosis of Vaginitis. ( 30874418 )
Successful mast-cell-targeted treatment of chronic dyspareunia, vaginitis, and dysfunctional uterine bleeding. ( 30964355 )
In Vitro Activity of Fenticonazole against Candida and Bacterial Vaginitis Isolates Determined by Mono- or Dual-Species Testing Assays. ( 31061161 )
Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis. ( 29632854 )
Bacterial Vaginosis and Desquamative Inflammatory Vaginitis. ( 30575452 )
Efficacy and safety of combined high-dose interferon and red light therapy for the treatment of human papillomavirus and associated vaginitis and cervicitis: A prospective and randomized clinical study. ( 30213012 )
Application of conjugated estrogen cream in the treatment of postmenopausal atrophic vaginitis. ( 30463825 )
Inguinal Hyperhidrosis: Case Report of an Uncommon Cause of Vaginitis. ( 29421341 )
Is non-response to fluconazole maintenance therapy for recurrent Candida vaginitis related to sensitization to atopic reactions? ( 29469170 )
Prevention practices of vaginitis among Malaysian women and its associated factors. ( 29526143 )
Candida vaginitis: virulence, host response and vaccine prospects. ( 29538739 )
Diagnostic Performance of a Molecular Test versus Clinician Assessment of Vaginitis. ( 29643195 )
Vaginitis: Diagnosis and Treatment. ( 29671516 )
Vaginitis. ( 29671518 )
Therapeutic Approaches to Atrophic Vaginitis in Postmenopausal Women: A Systematic Review with a Network Meta-analysis of Randomized Controlled Trials. ( 29765921 )
Iron Restriction to Clinical Isolates of Candida albicans by the Novel Chelator DIBI Inhibits Growth and Increases Sensitivity to Azoles In Vitro and In Vivo in a Murine Model of Experimental Vaginitis. ( 29844048 )
Abnormal vaginal microbioma is associated with severity of localized provoked vulvodynia. Role of aerobic vaginitis and Candida in the pathogenesis of vulvodynia. ( 29934834 )
Sexual behaviour and extra-genital colonisation in women treated for recurrent Candida vulvo-vaginitis. ( 29998617 )
Effect of vaginal suppository on bacterial vaginitis based on Persian medicine (Iranian traditional medicine): a randomised double blind clinical study. ( 30084707 )
Effect of pea protein plus grape seed dry extract on a murine model of Candida albicans induced vaginitis. ( 30256168 )
17β-estradiol vaginal tablet versus conjugated equine estrogen vaginal cream to relieve menopausal atrophic vaginitis. ( 30358715 )
Cervical Ectropion May Be a Cause of Desquamative Inflammatory Vaginitis. ( 28460993 )
Tyndallized lactic ferments: new possible therapies in treating vaginitis. ( 28116891 )
Syndromic Diagnosis in Evaluation of Women with Symptoms of Vaginitis. ( 28210940 )
Determination of factors affecting relapse of vaginitis among reproductive-aged women: An experimental study. ( 28243399 )
An epidemiological study on vaginitis in 6,150 women of reproductive age in Shanghai. ( 28255605 )
Highly efficient treatment of aerobic vaginitis with simple acidic buffered gels: The importance of pH and buffers on the microenvironment of vaginas. ( 28414136 )
Prevalence of vaginitis in different age groups among females in Greece. ( 28468531 )
Vaginitis: Beyond the Basics. ( 28499528 )
Aerobic vaginitis: no longer a stranger. ( 28502874 )
Clinical Validation of a Test for the Diagnosis of Vaginitis. ( 28594779 )
Overexpression of Candida albicans Secreted Aspartyl Proteinases 2 or 5 is not sufficient for exacerbation of immunopathology in a murine model of vaginitis. ( 28760935 )
Effect of the vaginal pessaries Melanizol® and Klimedeks® on the glycogen level in the vaginal tissue of rats on the background of experimental vaginitis. ( 28914070 )
Clinical Validation of a Test for the Diagnosis of Vaginitis. ( 28937557 )
Role of Molecular Biology in Diagnosis and Characterization of Vulvo-Vaginitis in Clinical Practice. ( 29017160 )
Chitosan Ascorbate Nanoparticles for the Vaginal Delivery of Antibiotic Drugs in Atrophic Vaginitis. ( 29048359 )
Loop-Mediated Isothermal Amplification on Crude DNA as a Point-of-Care Test for the Diagnosis of Mycoplasma-Related Vaginitis During Early Pregnancy. ( 29272448 )
The Threat of Aerobic Vaginitis to Pregnancy and Neonatal Morbidity. ( 29624945 )

Variations for Vaginitis

Expression for Vaginitis

Search GEO for disease gene expression data for Vaginitis.

Pathways for Vaginitis

Pathways related to Vaginitis according to GeneCards Suite gene sharing:

(show all 29)
# Super pathways Score Top Affiliating Genes
1 12.52 AR CXCL8 ESR1 ESR2 FN1 IL6
Show member pathways
Show member pathways
11.98 AR EZR IL6
Show member pathways
11.91 FN1 IL1B IL6
5 11.88 CXCL8 IL1B IL6
6 11.79 CXCL8 FN1 IL1B IL6
7 11.78 AR ESR1 ESR2
Show member pathways
11.75 AR ESR1 ESR2
9 11.75 CXCL8 IL1B IL6
10 11.73 CXCL8 FN1 IL1B IL6
11 11.72 CXCL8 IL1B IL6
12 11.67 CXCL8 FN1 IL1B IL6
13 11.66 CXCL8 IL1B IL6
Show member pathways
15 11.56 CXCL8 IL1B IL6
Show member pathways
11.55 CXCL8 IL1B IL6
17 11.54 CXCL8 FN1 IL1B IL6
18 11.53 CXCL8 EZR FN1
19 11.46 CXCL8 IL1B IL6
20 11.39 CXCL8 IL1B IL6
21 11.38 CXCL8 IL1B IL6
22 11.31 AR IL1B IL6
23 11.23 AR CXCL8 ESR2 IL1B IL6
24 11.15 CXCL8 EZR FN1
25 11.07 CXCL8 EZR IL1B IL6
26 11 ESR1 ESR2
27 10.89 CXCL8 EZR FN1 IL1B IL6
28 10.61 CXCL8 FN1 IL6
29 10.1 ESR1 ESR2

GO Terms for Vaginitis

Biological processes related to Vaginitis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.8 AR CXCL8 IL1B IL6
2 positive regulation of transcription, DNA-templated GO:0045893 9.72 AR ESR1 ESR2 IL1B IL6
3 cytokine-mediated signaling pathway GO:0019221 9.67 CXCL8 FN1 IL1B IL6
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.65 AR IL1B IL6
5 cell-cell signaling GO:0007267 9.56 AR ESR2 IL1B SH2D1A
6 negative regulation of neurogenesis GO:0050768 9.52 IL1B IL6
7 intracellular estrogen receptor signaling pathway GO:0030520 9.46 ESR1 ESR2
8 mammary gland alveolus development GO:0060749 9.43 AR ESR1
9 positive regulation of glial cell proliferation GO:0060252 9.4 IL1B IL6
10 positive regulation of gene expression GO:0010628 9.35 AR EZR FN1 IL1B IL6
11 positive regulation of neutrophil chemotaxis GO:0090023 9.21 CXCL8
12 positive regulation of neuroinflammatory response GO:0150078 9.16 IL1B IL6
13 positive regulation of DNA-binding transcription factor activity GO:0051091 8.92 ESR1 ESR2 IL1B IL6

Molecular functions related to Vaginitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.73 AR ESR1 ESR2 FN1
2 ATPase binding GO:0051117 9.54 AR ESR1 EZR
3 steroid hormone receptor activity GO:0003707 9.43 AR ESR1 ESR2
4 estrogen receptor activity GO:0030284 9.32 ESR1 ESR2
5 estrogen response element binding GO:0034056 9.16 ESR1 ESR2
6 nuclear receptor activity GO:0004879 9.13 AR ESR1 ESR2
7 steroid binding GO:0005496 8.8 AR ESR1 ESR2
8 protein binding GO:0005515 10.22 ABCB1 AR CXCL8 DEFB4A DLAT ESR1

Sources for Vaginitis

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
33 HPO
34 ICD10
35 ICD10 via Orphanet
39 LifeMap
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
56 Novoseek
59 OMIM via Orphanet
63 PubMed
71 SNOMED-CT via Orphanet
73 Tocris
75 UMLS via Orphanet
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