MCID: VRL002
MIFTS: 29

Variola Minor

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Variola Minor

MalaCards integrated aliases for Variola Minor:

Name: Variola Minor 12 15 74
Cottonpox 12
Alastrim 12
Whitepox 12
Milkpox 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9153
ICD9CM 36 050.1
MeSH 45 D012899
NCIt 51 C34365
SNOMED-CT 69 72294005
UMLS 74 C0001906

Summaries for Variola Minor

Disease Ontology : 12 A smallpox that results in milder infection, located in skin, has material basis in Variola virus. The infection results in_formation_of lesions.

MalaCards based summary : Variola Minor, also known as cottonpox, is related to variola major and smallpox. An important gene associated with Variola Minor is SPAG9 (Sperm Associated Antigen 9), and among its related pathways/superpathways are Creation of C4 and C2 activators and Complement and coagulation cascades. Affiliated tissues include skin, skin and testes.

Wikipedia : 77 Smallpox was an infectious disease caused by one of two virus variants, Variola major and Variola minor.... more...

Related Diseases for Variola Minor

Diseases related to Variola Minor via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 variola major 11.6
2 smallpox 11.6
3 monkeypox 10.5
4 chickenpox 10.1
5 cowpox 10.1
6 vaccinia 10.1
7 cardiomyopathy, familial hypertrophic, 2 9.6 CD55 SPAG9

Graphical network of the top 20 diseases related to Variola Minor:



Diseases related to Variola Minor

Symptoms & Phenotypes for Variola Minor

Drugs & Therapeutics for Variola Minor

Search Clinical Trials , NIH Clinical Center for Variola Minor

Genetic Tests for Variola Minor

Anatomical Context for Variola Minor

The Foundational Model of Anatomy Ontology organs/tissues related to Variola Minor:

20
Skin

MalaCards organs/tissues related to Variola Minor:

42
Skin, Testes

Publications for Variola Minor

Articles related to Variola Minor:

(show top 50) (show all 55)
# Title Authors Year
1
Variola minor in coalfield areas of England and Wales, 1921-34: Geographical determinants of a national smallpox epidemic that spread out of effective control. ( 28351006 )
2017
2
Differentiation of Variola major and Variola minor variants by MGB-Eclipse probe melt curves and genotyping analysis. ( 19345728 )
2009
3
Optimal vaccination schemes for epidemics among a population of households, with application to variola minor in Brazil. ( 17089950 )
2006
4
Alastrim smallpox variola minor virus genome DNA sequences. ( 10639322 )
2000
5
Comparative studies of gamma-interferon receptor-like proteins of variola major and variola minor viruses. ( 8612768 )
1996
6
The group selection of variola minor in the Americas: an anthroponootic analogue for the myxomatosis epizootic in Australia. ( 2423858 )
1986
7
The virology of variola minor. Correlation of laboratory tests with the geographic distribution and human virulence of variola isolates. ( 3004200 )
1986
8
The pathogenicity of variola virus. A comparison of the growth of standard strains of variola major and variola minor viruses in cell cultures from human embryos. ( 6296226 )
1982
9
Sequential analysis of the influence of sex on the spread of the disease variola minor. ( 7278313 )
1981
10
Facial scarring after varicella. A comparison with variola major and variola minor. ( 7315828 )
1981
11
Multivariate analysis of the role of school-attendance status in the introduction of variola minor into the household. ( 7330690 )
1981
12
Residual skin changes in patients who have recovered from variola minor. ( 6966543 )
1980
13
Population-dynamics models and a sequential test in the analysis of the influence of household setting on the spread of Variola minor. ( 7401659 )
1980
14
An analysis of the influence of age and school-attendance status on the spread of variola minor. ( 431093 )
1979
15
Variola minor in Bragança Paulista county, 1956. Observations on the clinical course of variola minor and on pregnancy in women with the disease. ( 498383 )
1979
16
Variola minor in Braganca Paulista County, 1956: household aggregation of the disease and the influence of household size on the attack rate. ( 762399 )
1979
17
Variola minor in Bragança Paulista County, 1956: propagating-rate analysis of the spread of variola minor in two elementary schools. ( 743767 )
1978
18
Variola minor in Bragança Paulista County, 1956. Distribution of onset of cases in the two schools including most school children with variola. ( 743773 )
1978
19
Variola minor in Bragança Paulista County, 1956. Respiratory manifestations in cases of variola and in household contacts of cases. ( 580911 )
1977
20
Analysis of the incidence of variola minor in an outbreak by use of a mathematical model. ( 842777 )
1977
21
Variola minor in Braganca Paulista county, 1956: a trend-surface analysis. ( 848476 )
1977
22
Variola minor in Bragança Paulista County, 1956. Plan of the serological study and some general results. ( 199364 )
1976
23
Variola minor in Bragança Paulista County, 1956: overall description of the epidemic and of its study. ( 1010665 )
1976
24
Variola minor in Bragança Paulista county, 1956. Attack rates in various population units of the two schools including most students with the disease. ( 1247007 )
1976
25
Variola minor in Braganca Paulista County, 1956. Flow of the epidemic through the schools of the county. ( 1163174 )
1975
26
Variola minor in Bragança Paulista County, 1956: lack of evidence indicating the influence of contaminated classrooms on spread of the disease. ( 4522722 )
1974
27
Variola minor in Bragança Paulista County, 1956: space-time interactions among variola minor cases in two elementary schools. ( 4811176 )
1974
28
Spread of variola minor among vaccinated members of a household. ( 4767569 )
1973
29
Epidemiology of variola minor in Brazil based on a study of 33 outbreaks. ( 4537480 )
1972
30
A clinical and laboratory study of smallpox in Brazil. Accuracy of the laboratory diagnosis of smallpox in patients with Brazilian variola minor infection. ( 5533180 )
1970
31
The clinical and laboratory diagnosis of variola minor (alastrim). ( 4319183 )
1970
32
The inhibition of variola minor virus multiplication by rifampicin. ( 4321450 )
1970
33
The survival of smallpox virus (variola minor) in natural circumstances. ( 4299528 )
1968
34
Sociological factors in the spread of variola minor in a semi-rural school district. ( 5239071 )
1968
35
Variola minor. Observations and experiences in Staffordshire, England, during 1966. ( 4292686 )
1967
36
The mechanism of spread of variola minor in a hospital ward. ( 5304374 )
1967
37
Variola minor in the United States. ( 6047884 )
1967
38
Spread of variola minor in households. ( 6081380 )
1967
39
Variola minor. A preliminary report from the Birmingham Hospital region. ( 4160887 )
1966
40
Variola minor. ( 5939180 )
1966
41
Diagnosis of variola minor. ( 5945552 )
1966
42
Methisazone in prevention of variola minor among contacts. ( 4159212 )
1965
43
CLINICAL AND SUBCLINICAL VARIOLA MINOR IN A WARD OUTBREAK. ( 14271927 )
1965
44
VARIOLA MINOR IN A PRIMARY SCHOOL. ( 14139778 )
1964
45
LOSS OF IMMUNITY AGAINST VACCINIA AFTER ATTACK OF VARIOLA MINOR. ( 14171101 )
1964
46
Epidemic of variola minor in a suburb of São Paulo. ( 19316438 )
1963
47
The laboratory differentiation between variola major and variola minor. ( 13888357 )
1961
48
Smallpox and alastrim; use of the chick embryo to distinguish between the viruses of variola major and variola minor. ( 13429852 )
1957
49
Secondary bacterial infection of the skin lesions of Variola minor. ( 13054531 )
1953
50
Variola minor in Rochdale and district, 1951-52. ( 13056133 )
1953

Variations for Variola Minor

Expression for Variola Minor

Search GEO for disease gene expression data for Variola Minor.

Pathways for Variola Minor

GO Terms for Variola Minor

Cellular components related to Variola Minor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 8.92 CD46 CD55 ITM2B SPAG9

Biological processes related to Variola Minor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 complement activation, classical pathway GO:0006958 9.16 CD46 CD55
2 regulation of complement activation GO:0030449 8.96 CD46 CD55
3 viral entry into host cell GO:0046718 8.62 CD46 CD55

Molecular functions related to Variola Minor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 virus receptor activity GO:0001618 8.62 CD46 CD55

Sources for Variola Minor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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