Vas Deferens, Congenital Bilateral Aplasia of, X-Linked disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

CBAVDX MCID: VSD001 MIFTS: 28	Vas Deferens, Congenital Bilateral Aplasia of, X-Linked (CBAVDX) Categories: Genetic diseases, Reproductive diseases
Genes Variations Tissues Related diseases Publications Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

MalaCards integrated aliases for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Name: Vas Deferens, Congenital Bilateral Aplasia of, X-Linked ⁵⁶ ²⁹ ⁶

Cbavdx ⁵⁶ ¹² ⁷³

Congenital Bilateral Absence of Vas Deferens, X-Linked ⁵⁶ ²⁹

Male Urogenital Diseases ⁴³ ⁷¹

Congenital Bilateral Aplasia of the Vas Deferens, X-Linked ⁷³

X-Linked Congenital Bilateral Absence of Vas Deferens ¹²

Characteristics:

OMIM:

⁵⁶

Inheritance:
x-linked

HPO:

³¹

vas deferens, congenital bilateral aplasia of, x-linked:
Inheritance x-linked inheritance

Classifications:

MalaCards categories:
Global: Genetic diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0111863

OMIM ⁵⁶ 300985

OMIM Phenotypic Series ⁵⁶ PS277180

MeSH ⁴³ D052801

MedGen ⁴¹ C4310815 CN238523

SNOMED-CT via HPO ⁶⁸ 263934009 300506000 425558002 more

UMLS ⁷¹ C1720894

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Summaries for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

OMIM : ⁵⁶ Congenital bilateral absence of the vas deferens (CBAVD) is found in more than 25% of men with obstructive azoospermia, involving a complete or partial defect of the Wolffian duct derivatives. In 80% of men with CBAVD (see 277180), mutations are identified in the CFTR gene (602421). The forms caused by mutations in the CFTR and ADGRG2 genes are clinically indistinguishable (summary by Patat et al., 2016). (300985)

MalaCards based summary : Vas Deferens, Congenital Bilateral Aplasia of, X-Linked, also known as cbavdx, is related to renal hypodysplasia/aplasia 1 and vas deferens, congenital bilateral aplasia of, and has symptoms including pathological conditions, signs and symptoms An important gene associated with Vas Deferens, Congenital Bilateral Aplasia of, X-Linked is ADGRG2 (Adhesion G Protein-Coupled Receptor G2). The drugs Tamsulosin and Adrenergic alpha-Antagonists have been mentioned in the context of this disorder. Affiliated tissues include prostate, and related phenotypes are azoospermia and absent vas deferens

Disease Ontology : ¹² A congenital bilateral absence of vas deferens that has material basis in mutation in ADGRG2 on chromosome Xp22.13.

UniProtKB/Swiss-Prot : ⁷³ Congenital bilateral aplasia of the vas deferens, X-linked: A disease characterized by bilateral absence of vas deferens, obstructive azoospermia, and infertility.

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Related Diseases for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Diseases related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score
1	renal hypodysplasia/aplasia 1	10.3
2	vas deferens, congenital bilateral aplasia of	10.3
3	azoospermia	10.3
4	infertility	10.3
5	male infertility	9.8
6	balanoposthitis	9.8
7	urethritis	9.8
8	prostatitis	9.8

Graphical network of the top 20 diseases related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

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Symptoms & Phenotypes for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Human phenotypes related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

³¹

#	Description	HPO Frequency	HPO Source Accession
1	azoospermia ³¹		HP:0000027
2	absent vas deferens ³¹		HP:0012873

Symptoms via clinical synopsis from OMIM:

⁵⁶

Genitourinary Internal Genitalia Male:
azoospermia
absent vas deferens
low semen volume
reduced testicular volume (in some patients)
acid ph of semen (in some patients)
more

Clinical features from OMIM:

300985

UMLS symptoms related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

pathological conditions, signs and symptoms

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Drugs & Therapeutics for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Drugs for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Tamsulosin

Approved, Investigational

Phase 2, Phase 3

106133-20-4

129211

Synonyms:

(−)-tamsulosin

(R)-(−)-tamsulosin

(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulphonamide

106133-20-4

5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide

5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide

5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide

5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide

5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulphonamide

5-{(2R)-2-[(2-{[2-(ethyloxy)phenyl]oxy}ethyl)amino]propyl}-2-(methyloxy)benzenesulfonamide

AC1L2V76

BIDD:GT0261

C07124

C20H28N2O5S

CHEBI:9398

CHEMBL836

CID129211

D08560

DB00706

Flomax

Flomax (TN)

Flowmax

FT-0082894

Harnal

HMS2090P15

LS-31578

MolPort-003-850-388

NCGC00167442-01

Omnic

Pradif

STK626950

Tamsolusin

Tamsulon

Tamsulon (TN)

tamsulosin

Tamsulosin

TAMSULOSIN

Tamsulosin (INN)

Tamsulosin [INN:BAN]

Tamsulosin hydrochloride

Tamsulosina

Tamsulosina [INN-Spanish]

Tamsulosine

Tamsulosine [INN-French]

Tamsulosinum

Tamsulosinum [INN-Latin]

UNII-G3P28OML5I

YM-617

Adrenergic alpha-Antagonists

Phase 2, Phase 3

Cholinergic Agents

Phase 2, Phase 3

Adrenergic Agents

Phase 2, Phase 3

Adrenergic Antagonists

Phase 2, Phase 3

Muscarinic Antagonists

Phase 2, Phase 3

Tolterodine tartrate

Phase 2, Phase 3

124937-52-6

Cholinergic Antagonists

Phase 2, Phase 3

Adrenergic alpha-1 Receptor Antagonists

Phase 2, Phase 3

Neurotransmitter Agents

Phase 2, Phase 3

Selenium

Approved, Investigational, Vet_approved

Phase 2

7782-49-2

Synonyms:

Se(2+)

Se2+

Selanediide

Selen

Selenide

Selenide(2-)

Selenio

Sélénium

Selenium dication

Selenium elemental

Selenium ion (se2+)

Selenium metallicum

Selenium, elemental

Tocopherol

Approved, Investigational

Phase 2

1406-66-2, 54-28-4

14986

Synonyms:

3,4-dihydro-2,7,8-Trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol

7,8-Dimethyltocol

7,8-dimethyltocolo-Xylotocopherol

Abortosan

adisseo Brand OF tocopherol

Alcala brand OF tocopherol acetate

Aliud brand OF tocopherol

Antioxidans e-hevert

Aquasol e

Arkopharma brand OF tocopherol acetate

AstraZeneca brand OF tocopherol acetate

Atarost brand OF tocopherol acetate

Ausrichter brand OF tocopherol

Auxina e

Balkanpharma brand OF tocopherol

Bayer brand OF tocopherol acetate

bio e

Biocur brand OF tocopherol acetate

biopto-e

Biosan

Bioweyxin

Blackmores brand OF tocopherol

Bottger brand OF tocopherol acetate

Cambridge laboratories brand OF tocopherol actetate

Dal e

Dal vita brand OF vitamin e succinate

Dal-e

Dal-vita brand OF vitamin e succinate

Davitamon

Dermorelle

Detulin

D-gamma-Tocopherol

DL-alpha-Tocopherol

DL-a-Tocopherol

DL-α-tocopherol

Dragees, vitamin-e

e Ferol

e Mulsin

e Vicotrat

e Vitamin e

Ecoro

e-Ferol

Elex verla

Embial

e-Mulsin

Ephynal

Eplonat

Equivit e

Eu rho brand OF tocopherol

EUNOVA vitamin e

Eusovit

e-Vicotrat

EVI-mirale, vitamin-e

Evion

e-Vitamin-ratiopharm

GNR Pharma brand OF tocopherol actetate

GNR-Pharma brand OF tocopherol actetate

Grace brand OF tocopherol

Grunwalder brand OF tocopherol

g-Tocopherol

Hervert brand OF tocopherol acetate

Heyl brand OF tocopherol acetate

Hydrovit e

ICN brand OF tocopherol acetate

Infirmarius rovit brand OF tocopherol

Infirmarius-rovit brand OF tocopherol

Internation animal health brand OF tocopherol acetate

Jenapharm brand OF tocopherol

Kentucky brand OF tocopherol

Kohler brand OF tocopherol

Lasar

Malton e

medphano Brand OF tocopherol acetate

Merck brand OF tocopherol acetate

Methyltocols

Micorvit e

MIP brand OF tocopherol acetate

Mowivit vitamin e

Mucos brand OF tocopherol acetate

Organon brand OF tocopherol acetate

O-Xylotocopherol

puncto e

Ratiopharm brand OF tocopherol

Richelet brand OF tocopherol acetate

Richtavit e

Riemser brand OF tocopherol

Roche nicholas brand OF tocopherol acetate

Rodisma med brand OF tocopherol

Rodisma-med brand OF tocopherol

Sanavitan S

Sanum kehlbeck brand OF tocopherol actetate

Sanum-kehlbeck brand OF tocopherol actetate

Schwarzhaupt brand OF tocopherol acetate

Sciencex brand OF tocopherol acetate

Scot tussin brand OF tocopherol acetate

Scot-tussin brand OF tocopherol acetate

Snow-e muscle, energy and feritility

Spondyvit

Stadapharm brand OF tocopherol

Steigerwald brand OF tocopherol acetate

Strathmann brand OF tocopherol

tocoferol

tocoferoles

Tocolion

Tocopa

Tocopharm

Tocopherol

tocophérol

Tocopherol ausrichter brand

Tocopherol balkanpharma brand

Tocopherol bayer

Tocopherol grace brand

Tocopherol grunwalder brand

Tocopherol infirmarius-rovit brand

Tocopherol kentucky brand

Tocopherol ratiopharm brand

Tocopherol rodisma-med brand

Tocopherol stadapharm brand

Tocopherol togal brand

Tocopherol twardy brand

Tocopherol verla brand

Tocopherol wiedemann brand

Tocopherol worwag brand

Tocopherols

Tocovital

Togal brand OF tocopherol

Togasan vitamin e

Troyapharm brand OF tocopherol acetate

Twardy brand OF tocopherol

Unique e

uno Vit

uno-Vit

UnoVit

Verla brand OF tocopherol

Veyx brand OF tocopherol

Vibolex

Vit e hydrosol

Vit. e stada

Vita e

Vita plus e

Vita-e

VitaE

Vitagutt vitamin e

Vitamin e al

Vitamin e dragees

Vitamin e evi mirale

Vitamin e gamma

Vitamin e MP

Vitamin e natur

Vitamin e sanum

Vitamin e suspension

Vitamin e, mowivit

Vitamin e, togasan

Vitamin e, vitagutt

Vitamin emp

Vitamin e-MP

Vitamin-e dragees

Vitamine e GNR

Vitamin-e evi-mirale

Vita-plus e

VitaPlus e

Vitazell

Wiedemann brand OF tocopherol

Wiedemann brand OF vitamin e succinate

Woelm brand OF tocopherol acetate

Worwag brand OF tocopherol

γ-tocopherol

Lycopene

Approved, Investigational

Phase 2

502-65-8

53477748

Vitamin E

Approved, Nutraceutical, Vet_approved

Phase 2

59-02-9

14985

Synonyms:

(+)-alpha-Tocopherol

(+)-a-Tocopherol

(+)-α-tocopherol

(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL

(2R)-3,4-dihydro-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol

(2R,4'r,8'r)-alpha-Tocopherol

(2R,4'r,8'r)-a-Tocopherol

(2R,4'r,8'r)-α-tocopherol

(2R,4'R,8'R)-α-tocopherol

(R,R,R)-alpha-Tocopherol

(R,R,R)-a-Tocopherol

(R,R,R)-α-tocopherol

5,7,8-trimethyltocol

5,7,8-Trimethyltocol

a-D-Tocopherol

alpha-delta-Tocopherol

alpha-tocopherol

alpha-Tocopherol

Amino-Opti-E

Aquasol E

a-Tocopherol

D-alpha-Tocopherol

Daltose

D-a-Tocopherol

delta-alpha-Tocopherol

Denamone

d-α-tocopherol

D-α-tocopherol

E-200 I.U. Softgels

E-Complex-600

E-Ferol

Eprolin

E-Vitamin succinate

Gordo-Vite E

Phytogermin

Phytogermine

RRR-alpha-Tocopherol

RRR-alpha-Tocopheryl

Tocopherol

Vitamin e

Vitamin ea

Vitamin Plus E Softgells

Vitec

α-tocopherol

Vitamin D3

Approved, Nutraceutical

Phase 2

67-97-0

5280795 6221

Synonyms:

()-Vitamin D3

(+)-vitamin D3

(+)-Vitamin D3

(1S,3Z)-3-[(2E)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol

(3 beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

(3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(3Β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol

(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(5Z,7E)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

1406-16-2

25(OH)D

47763_SUPELCO

57651-82-8

67-97-0

7-DEHYDROCHOLESTEROL

7-Dehydrocholesterol activated

7-Dehydrocholesterol, Activated

7-Dehydrocholesterol, irradiated

7-Dehydrocholestrol, activated

8024-19-9

8050-67-7

89193_FLUKA

9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol

9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol

9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol

9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol

AB1002422

AC-11697

AC1L1ECK

AC1L1M23

AC1LU7IZ

AC1NQXLN

AC1NR2UO

AC1NR2UR

AC1NR2UU

AC1NS4AJ

AC1NSHJX

AC1O5EOF

AC1O7GAV

AC1O7GQ3

AC1O8FEU

AC1O8PWJ

AC1OF2GI

AC1OF2GL

AC1OIEW5

AC1OIEWB

ACon1_001997

ACTIVATED

Activated 7-dehydrocholesterol

Arachitol

Bio-0845

bmse000507

BPBio1_000460

BSPBio_000418

BSPBio_002408

C05443

C1357_SIAL

C27H44O

C9756_SIGMA

C9774_SIAL

Calciol

CAS-67-97-0

CCRIS 5813

CCRIS 6286

CHEBI:283119

CHEBI:28940

CHEMBL1042

CHEMBL432780

cholecalciferol

Cholecalciferol

Cholecalciferol (D3)

Cholecalciferol (JP15/USP)

Cholecalciferol [USAN:BAN:JAN]

Cholecalciferol, D3

Cholecalciferols

Cholecalciferolum

CID10000117

CID10045875

CID10340013

CID10883523

CID10894379

CID11014566

CID11025493

CID11058152

CID11463269

CID1548921

CID2735

CID5280795

CID5283710

CID5283711

CID5283712

CID5353527

CID5363362

CID6221

CID6432644

CID6604201

CID6604662

CID6708595

CID6713938

CID6992015

CID6992016

CID7067439

CID7067440

CID7251172

CID7251174

CID9821465

Colecalciferol

Colecalciferol (INN)

Colecalciferolo

Colecalciferolo [DCIT]

Colecalciferolum

Colecalciferolum [INN-Latin]

Colecalcipherol

D00188

D3-Vicotrat

D3-Vigantol

DB00169

Delsterol

Delta-D

Delta-D (TN)

Deparal

Dihydrocholesterol

DivK1c_006276

Duphafral D3 1000

Ebivit

EINECS 200-673-2

EINECS 215-797-2

EPA Pesticide Chemical Code 202901

FeraCol

HMS1569E20

HMS2092M12

HSDB 820

I05-0041

Irradiated 7-dehydrocholesterol

KBio1_001220

KBio2_001643

KBio2_004211

KBio2_006779

KBio3_001628

KBioGR_001602

KBioSS_001643

LMST03020001

LMST03020219

LMST03020220

LMST03020221

LS-1570

LS-825

LT00244775

MEGxm0_000458

Micro-dee

MolPort-001-740-051

MolPort-001-785-972

MolPort-003-666-021

MolPort-004-946-964

NCGC00016301-01

NCGC00017328-01

NCGC00091072-01

NCGC00142511-01

NCGC00159331-02

NCGC00159331-04

NCGC00178668-01

NCGC00179565-01

NCGC00179565-02

NEO Dohyfral D3

NSC 375571

NSC375571

NSC-375571

Oleovitamin D3

Prestwick_63

Prestwick0_000429

Prestwick1_000429

Prestwick2_000429

Prestwick3_000429

Provitamine

Provitina

Rampage

Ricketon

SMP1_000068

SPBio_001298

SPBio_002357

SpecPlus_000180

Spectrum_001163

Spectrum2_001369

Spectrum3_000764

Spectrum4_001201

SR-05000001559

SR-05000001559-3

ST057172

TNP00266

Trivitan

UNII-1C6V77QF41

UPCMLD-DP152

UPCMLD-DP152:001

Vi-de-3-hydrosol

Vigorsan

VITAMIN D

Vitamin D 3

vitamin d-3

Vitamin D3

Vitamin D-3

Vitamin D3 emulsifiable

VITAMIN D3 POWDER

VITAMIN_D3

Vitinc Dan-Dee-3

ZINC04474460

ZINC04492874

ZINC04492875

ZINC04492876

ZINC04492878

δ-D

Vitamin D

Approved, Nutraceutical, Vet_approved

Phase 2

1406-16-2

Tocotrienol

Investigational

Phase 2

6829-55-6

Tea

Phase 2

Trace Elements

Phase 2

Vitamins

Phase 2

Antioxidants

Phase 2

Hormones

Phase 2

Protective Agents

Phase 2

Nutrients

Phase 2

Tocotrienols

Phase 2

Micronutrients

Phase 2

Calcium, Dietary

Phase 2

Tocopherols

Phase 2

Radiation-Protective Agents

Phase 2

Calciferol

Phase 2

Anti-Inflammatory Agents

Phase 2

Calcium

Nutraceutical

Phase 2

7440-70-2

271

Synonyms:

Blood coagulation factor XIII

Ca(2+)

Ca2+

Calcio

Calcium

Calcium element

CALCIUM ion

Calcium, doubly charged positive ion

Calcium, elemental

Coagulation factor XIII

Elemental calcium

Factor XIII

Factor XIII a chain

Factor XIII a-chain

Factor XIII transamidase

Factor XIII, coagulation

Fibrin stabilizing factor

Fibrinase

Kalzium

Laki lorand factor

Laki-lorand factor

Stabilizing factor, fibrin

Transamidase, factor XIII

XIII, coagulation factor

Nimodipine

Approved, Investigational

66085-59-4

4497

Synonyms:

1,4-Dihydro-2,6-dimethyl-4-(3&prime

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester

1-methylethyl 2-(methyloxy)ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 3-beta-methoxyethyl ester 5-isopropyl ester

2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 3-b-methoxyethyl ester 5-isopropyl ester

2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 3-β-methoxyethyl ester 5-isopropyl ester

2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester

2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-b-methoxyethyl ester 5-isopropyl ester

2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-methoxyethyl ester 5-isopropyl ester

2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-methoxyethyl ester 5-isopropyl ester

2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

2-Methoxyethyl-1-methylethyl ester

3-(2-methoxyethyl) 5-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

3,5-pyridinecarboxylic acid 2-methoxyethyl 1-methylethyl ester

3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl), 2-methoxyethyl 1-methylethyl ester

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-methoxyethyl 1-methylethyl ester

3-O-(2-methoxyethyl) 5-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-N,N-dimethyl-2,2-diphenyl-butanamide

66085-59-4

9736, Bay e

AB00513963

AC-11694

AC1L1IAS

AC1Q4G7S

Admon

Almirall brand OF nimodipine

Almirall Brand of Nimodipine

Alpharma brand OF nimodipine

Alpharma Brand of Nimodipine

andromaco Brand OF nimodipine

Andromaco Brand of Nimodipine

BAY e 9736

Bay-E 9736

Bay-e-9736

Bayer brand OF nimodipine

Bayer Brand of Nimodipine

Bayvit brand OF nimodipine

Bayvit Brand of Nimodipine

Bayvit, nimodipino

Bio-0178

Bio1_000118

Bio1_000607

Bio1_001096

Bio2_000117

Bio2_000597

BPBio1_000876

Brainal

BRD-A58048407-001-06-3

BRN 0459792

BSPBio_000796

BSPBio_001397

BSPBio_002412

C07267

C21H26N2O7

Calnit

Cantabria brand OF nimodipine

Cantabria Brand of Nimodipine

CBiol_001832

CHEBI:160965

CHEBI:465248

CHEMBL1428

CHEMBL40792

CID4497

CPD000058300

D00438

D009553

DB00393

DivK1c_006812

DRG-0139

e 9736, Bay

EG-1961

EINECS 266-127-0

Elan brand OF nimodipine

Elan Brand of Nimodipine

Esteve brand OF nimodipine

Esteve Brand of Nimodipine

EU-0100891

FT-0082761

Hexal brand OF nimodipine

Hexal Brand of Nimodipine

Hexal, nimodipin

HMS1361F19

HMS1570H18

HMS1791F19

HMS1922E04

HMS1989F19

HMS2052M05

HMS2089H13

HMS2093G11

I06-0230

IDI1_033867

isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid

isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate

Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate

Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylic acid

KBio1_001756

KBio2_000117

KBio2_002403

KBio2_002685

KBio2_004971

KBio2_005253

KBio2_007539

KBio3_000233

KBio3_000234

KBio3_001632

KBioGR_000117

KBioGR_001262

KBioSS_000117

KBioSS_002408

Kenesil

Lopac0_000891

LS-131292

MLS000069381

MLS000863294

MLS001076550

MLS002154061

MLS002172461

Modus

MolPort-001-840-190

N-149

N149_SIGMA

NCGC00015714-04

NCGC00015714-12

NCGC00024675-02

NCGC00024675-03

NCGC00024675-04

NCGC00024675-05

NCGC00024675-06

NCGC00024675-07

NCGC00024675-08

NCGC00024675-09

nchembio.476-comp9

nchembio.79-comp6

Nimodipin hexal

Nimodipin Hexal

Nimodipin isis

Nimodipin ISIS

nimodipine

Nimodipine

Nimodipine (USAN/INN)

Nimodipine [USAN:BAN:INN]

Nimodipin-isis

NimodipinISIS

Nimodipin-ISIS

Nimodipino

Nimodipino [INN-Spanish]

nimodipino Bayvit

Nimodipino Bayvit

Nimodipinum

Nimodipinum [INN-Latin]

NimoGel

Nimotop

NIMOTOP (TN)

Nimotop(TM)

Nimotop, Nimodipine

-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl-1-methylethyl Ester

Nymalize

Periplum

Periplum, Nimotop, BRN 0459792, DRG-0139

Prestwick0_000918

Prestwick1_000918

Prestwick2_000918

Prestwick3_000918

Remontal

S1747_Selleck

SAM001246890

SMR000058300

SPBio_001464

SPBio_002985

SpecPlus_000716

Spectrum_001880

SPECTRUM1503600

Spectrum2_001562

Spectrum3_000766

Spectrum4_000791

Spectrum5_001687

STK642934

UNII-57WA9QZ5WH

Vita brand OF nimodipine

Vita Brand of Nimodipine

Desflurane

Approved

57041-67-5

42113

Synonyms:

(+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether

(±)-2-difluoromethyl 1,2,2,2-tetrafluoroethyl ether

1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane

1,1,1,2-tetrafluoro-2-(Difluoromethoxy)ethane

2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane

57041-67-5

AC1L274J

AC1Q4ICY

Baxter anaesthesia brand OF desflurane

Baxter brand OF desflurane

C07519

C3H2F6O

CHEBI:4445

CHEMBL1200733

CID42113

D00546

DB01189

Desflurane

DESFLURANE

Desflurane (JAN/USP/INN)

Desflurane [USAN:INN]

Desflurano

Desflurano [INN-Spanish]

Desfluranum

Desfluranum [INN-Latin]

difluoromethyl 1,2,2,2-tetrafluoroethyl ether

Difluoromethyl 1,2,2,2-tetrafluoroethyl ether

I 653

I653

I-653

LS-65505

MolPort-001-776-387

Ohmeda brand OF desflurane

PC6781E

r-e 236ea1

Suprane

Suprane (TN)

UNII-CRS35BZ94Q

Zeneca brand OF desflurane

Anesthetics

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Combined Behavioral and Drug Treatment of Overactive Bladder in Men	Completed	NCT01175382	Phase 2, Phase 3	Tolterodine + tamsulosin
2	A Randomized, Double-Blind Study of Combination Vitamin E, Selenium and Lycopene vs. Placebo in Men Undergoing Radical Prostatectomy for Prostate Cancer	Completed	NCT00844792	Phase 2	Placebo
3	The Impact of Antioxidants on MRI Markers of Cell Proliferation and Hypoxia Among Men on Active Surveillance With Early Stage Prostate Cancer	Completed	NCT00744549	Phase 2	Placebo
4	Comparing Gas Consumption With Conventional Low Flow Ventilation and Gas Control Systems From Two Different Anesthesia Machines: Flow-i and Aisys	Completed	NCT02774031

Search NIH Clinical Center for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Cochrane evidence based reviews: male urogenital diseases

Sources

Genetic Tests for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Genetic tests related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

#	Genetic test	Affiliating Genes
1	Vas Deferens, Congenital Bilateral Aplasia of, X-Linked ²⁹	ADGRG2
2	Congenital Bilateral Absence of Vas Deferens, X-Linked ²⁹

Sources

Anatomical Context for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

MalaCards organs/tissues related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

⁴⁰

Prostate

Sources

Publications for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Articles related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

#	Title	Authors	PMID	Year
1	Truncating Mutations in the Adhesion G Protein-Coupled Receptor G2 Gene ADGRG2 Cause an X-Linked Congenital Bilateral Absence of Vas Deferens. ⁶ ⁵⁶	Patat O...Bieth E	27476656	2016
2	[Mycoplasma genitalium and male urogenital diseases: An update]. ⁶¹	Liu W...Shang XJ	30173450	2018
3	Effects of a dietary supplement on chronic pelvic pain syndrome (Category IIIA), leucocytospermia and semen parameters. ⁶¹	Lombardo F...Gandini L	22053857	2012

Sources

Genes for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Genes related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	ADGRG2	Adhesion G Protein-Coupled Receptor G2	Protein Coding	1008.71	Molecular basis known ⁵⁶ Pathogenic ⁶ Genetic Tests ²⁹ GeneCards inferred via : Variants (show sections)	27476656

Sources

Variations for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

ClinVar genetic disease variations for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

⁶ ‎‎ ‎‎ ‎‎

#	Gene	Name	Type	Significance	ClinVarId	dbSNP ID	GRCh37 Pos	GRCh38 Pos
1	ADGRG2	NM_001079858.3(ADGRG2):c.2845del (p.Cys949fs)	deletion	Pathogenic	253013	rs879255538	X:19013038-19013038	X:18994920-18994920
2	ADGRG2	NM_001079858.3(ADGRG2):c.2002_2006delinsAGA (p.Leu668fs)	indel	Pathogenic	253014	rs879255539	X:19021188-19021192	X:19003070-19003074
3	ADGRG2	NM_001079858.3(ADGRG2):c.1545dup (p.Glu516Ter)	duplication	Pathogenic	253015	rs774488954	X:19026118-19026119	X:19008000-19008001

Sources

Expression for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Search GEO for disease gene expression data for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked.

Sources

Pathways for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Sources

GO Terms for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Sources

Sources for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia

Vas Deferens, Congenital Bilateral Aplasia of, X-Linked (CBAVDX)

Aliases & Classifications for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

MalaCards integrated aliases for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Characteristics:

OMIM:

HPO:

Classifications:

External Ids:

Summaries for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Related Diseases for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Diseases related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Symptoms & Phenotypes for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Human phenotypes related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Symptoms via clinical synopsis from OMIM:

Clinical features from OMIM:

UMLS symptoms related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Drugs & Therapeutics for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Drugs for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Cochrane evidence based reviews: male urogenital diseases

Genetic Tests for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Genetic tests related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Anatomical Context for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

MalaCards organs/tissues related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Publications for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Articles related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Genes for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Genes related to Vas Deferens, Congenital Bilateral Aplasia of, X-Linked (1 elite genes):

Variations for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

ClinVar genetic disease variations for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked:

Expression for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Pathways for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

GO Terms for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked

Sources for Vas Deferens, Congenital Bilateral Aplasia of, X-Linked