Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: VSC007
MIFTS: 72

Vascular Disease

Categories: Blood diseases, Cardiovascular diseases, Gastrointestinal diseases, Mental diseases, Neuronal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
Sources

Aliases & Classifications for Vascular Disease

About this section

MalaCards integrated aliases for Vascular Disease:

Name: Vascular Disease 12 15 17
Vascular Diseases 56 44 45 74
Aneurysm 45 64 17 74
Spinal Cord Ischemia 45 17 74
Spinal Cord Vascular Diseases 45 74
Vascular Disease, Susceptibility to 13
Vascular Tissue Disease 12
Vascular Anomaly 56

Classifications:

MalaCards categories:
Anatomical: Mental diseases Gastrointestinal diseases Cardiovascular diseases Neuronal diseases Blood diseases
See all MalaCards categories (disease lists)
ICD10: 34


Sources

Summaries for Vascular Disease

About this section
MedlinePlus : 44 What are vascular diseases? Your vascular system is your body's network of blood vessels. It includes your Arteries, which carry oxygen-rich blood from your heart to your tissues and organs Veins, which carry the blood and waste products back to your heart Capillaries, which are tiny blood vessels that connect your small arteries to your small veins. The walls of the capillaries are thin and leaky, to allow for an exchange of materials between your tissues and blood. Vascular diseases are conditions which affect your vascular system. They are common and can be serious. Some types include Aneurysm - a bulge or "ballooning" in the wall of an artery Atherosclerosis - a disease in which plaque builds up inside your arteries. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Blood clots, including deep vein thrombosis and pulmonary embolism Coronary artery disease and carotid artery disease, diseases that involve the narrowing or blockage of an artery. The cause is usually a buildup of plaque. Raynaud's disease - a disorder that causes the blood vessels to narrow when you are cold or feeling stressed Stroke - a serious condition that happens when blood flow to your brain stops. Varicose veins - swollen, twisted veins that you can see just under the skin Vasculitis - inflammation of the blood vessels What causes vascular diseases? The causes of vascular diseases depend on the specific disease. These causes include Genetics Heart diseases such as high cholesterol and high blood pressure Infection Injury Medicines, including hormones Sometimes the cause is unknown. Who is at risk for vascular diseases? The risk factors for vascular diseases can vary, depending on the specific disease. But some of the more common risk factors include Age - your risk of some diseases goes up as you get older Conditions that can affect the heart and blood vessels, such as diabetes or high cholesterol Family history of vascular or heart diseases Infection or injury that damages your veins Lack of exercise Obesity Pregnancy Sitting or standing still for long periods of time Smoking What are the symptoms of vascular diseases? The symptoms for each disease are different. How are vascular diseases diagnosed? To make a diagnosis, your health care provider will do a physical exam and ask about your symptoms and medical history. You may have imaging tests and/or blood tests. How are vascular diseases treated? Which treatment you get depends on which vascular disease you have and how severe it is. Types of treatments for vascular diseases include Lifestyle changes, such as eating a heart-healthy diet and getting more exercise Medicines, such as blood pressure medicines, blood thinners, cholesterol medicines, and clot-dissolving drugs. In some cases, providers use a catheter to send medicine directly to a blood vessel. Non-surgical procedures, such as angioplasty, stenting, and vein ablation Surgery Can vascular diseases be prevented? There are steps you can take to help prevent vascular diseases: Make healthy lifestyle changes, such as eating a heart-healthy diet and getting more exercise Don't smoke. If you are already a smoker, talk to your health care provider for help in finding the best way for you to quit. Keep your blood pressure and cholesterol in check If you have diabetes, control your blood sugar Try not to sit or stand for up long periods of time. If you do need to sit all day, get up and move around every hour or so. If you traveling on a long trip, you can also wear compression stockings and regularly stretch your legs.

MalaCards based summary : Vascular Disease, also known as vascular diseases, is related to peripheral vascular disease and hepatic vascular disease, and has symptoms including angina pectoris, edema and chest pain. An important gene associated with Vascular Disease is MIR145 (MicroRNA 145), and among its related pathways/superpathways are Fluid shear stress and atherosclerosis and Selenium Micronutrient Network. The drugs Testosterone undecanoate and Testosterone enanthate have been mentioned in the context of this disorder. Affiliated tissues include endothelial, testes and kidney, and related phenotypes are cardiovascular system and homeostasis/metabolism

Disease Ontology : 12 A cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart.

NINDS : 55 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  A cerebral aneurysm can press on a nerve or surrounding tissue in the brain, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are more common in women than in men. These aneurysms can occur anywhere in the brain. Some small aneurysms may not show signs and are usually detected during imaging tests for other medical conditions. The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. A larger aneurysm that is steadily growing may produce symptoms such as numbness, pain above and behind the eye, and paralysis on one side of the face. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

PubMed Health : 64 About aneurysm: An aneurysm (AN-u-rism) is a balloon-like bulge in an artery. Arteries are blood vessels that carry oxygen-rich blood to your body.Arteries have thick walls to withstand normal blood pressure. However, certain medical problems, genetic conditions, and trauma can damage or injure artery walls. The force of blood pushing against the weakened or injured walls can cause an aneurysm.An aneurysm can grow large and rupture (burst) or dissect. A rupture causes dangerous bleeding inside the body. A dissection is a split in one or more layers of the artery wall. The split causes bleeding into and along the layers of the artery wall.Both rupture and dissection often are fatal.

Wikipedia : 77 Vascular disease is a class of diseases of the blood vessels – the arteries and veins of the circulatory... more...

Sources

Related Diseases for Vascular Disease

About this section

Diseases related to Vascular Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1577)
# Related Disease Score Top Affiliating Genes
1 peripheral vascular disease 35.0 ACE CRP SELP SERPINE1 VEGFA VWF
2 hepatic vascular disease 34.6 EDN1 MTHFR NOS3 SERPINE1 VWF
3 retinal vascular disease 34.4 ACE INS MTHFR VEGFA
4 buerger disease 33.6 MTHFR NOS3 SERPINE1
5 autosomal dominant polycystic kidney disease 33.3 ACE EDN1 NOS3 VEGFA
6 arteriosclerosis 32.9 ACE APOE CRP EDN1 ELN INS
7 thrombosis 32.8 MTHFR SELP SERPINE1 VWF
8 ischemia 32.7 ACE EDN1 KNG1 NOS3 SELP VEGFA
9 arteries, anomalies of 32.6 ACE APOE CRP EDN1 INS KNG1
10 cerebrovascular disease 32.6 ACE APOE CRP INS MMP9 MTHFR
11 renal artery disease 32.4 ACE NOS3
12 portal vein thrombosis 32.2 MTHFR SELP SERPINE1
13 vein disease 32.2 MTHFR SERPINE1 VEGFA
14 intermittent claudication 32.0 ACE CRP SELP SERPINE1 VEGFA VWF
15 aortic valve disease 1 31.7 ACE CRP ELN VWF
16 diabetes mellitus 31.5 ACE CRP EDN1 INS MIR145 NOS3
17 homocysteinemia 31.3 CRP MTHFR NOS3
18 heart disease 31.3 ACE APOE CRP EDN1 ELN INS
19 takayasu arteritis 31.2 CRP MMP9 VWF
20 kidney disease 31.2 ACE APOE CRP EDN1 INS NOS3
21 pulmonary hypertension 31.2 ACE EDN1 MIR21 NOS3 VWF
22 coronary artery anomaly 31.2 ACE CRP EDN1 KNG1 NOS3 SELP
23 impotence 31.2 EDN1 KNG1 NOS3
24 chronic kidney failure 31.2 ACE CRP EDN1 INS MTHFR NOS3
25 hemifacial spasm 31.2 MTHFR NOS3 VEGFA
26 coronary stenosis 31.2 ACE APOE CRP SERPINE1 VWF
27 atrial fibrillation 31.1 ACE CRP SELP VWF
28 ischemic colitis 31.0 MMP9 SERPINE1 VEGFA
29 retinal artery occlusion 31.0 ACE MTHFR SERPINE1 VEGFA
30 aortic disease 31.0 APOE CRP ELN MMP9
31 orthostatic intolerance 31.0 EDN1 ELN NOS3
32 systemic scleroderma 31.0 ACE CRP EDN1 SELP
33 sleep apnea 31.0 ACE APOE CRP EDN1 INS NOS3
34 ischemic heart disease 30.9 ACE APOE CRP MTHFR NOS3
35 atherosclerosis susceptibility 30.9 APOE CRP INS NOS3 SERPINE1
36 carotid stenosis 30.9 ACE APOE CRP MMP9 MTHFR SELP
37 aortic valve disease 2 30.9 ACE CRP ELN VWF
38 diabetes mellitus, noninsulin-dependent 30.9 ACE APOE CRP EDN1 INS MIR125A
39 limb ischemia 30.8 ACE EDN1 NOS3 VEGFA VWF
40 antiphospholipid syndrome 30.8 MTHFR SELP VWF
41 coronary heart disease 1 30.8 ACE APOE CRP INS MIR145 MTHFR
42 diabetic neuropathy 30.8 ACE INS VEGFA
43 aortic aneurysm, familial abdominal, 1 30.8 APOE ELN MMP9
44 peripheral artery disease 30.8 ACE CRP NOS3 SELP VEGFA
45 lipid metabolism disorder 30.8 ACE APOE CRP INS SERPINE1
46 angina pectoris 30.7 ACE CRP EDN1 NOS3
47 sexual disorder 30.7 ACE EDN1 NOS3
48 retinal vein occlusion 30.7 MTHFR SERPINE1 VEGFA
49 heart valve disease 30.6 ACE CRP ELN VWF
50 lemierre's syndrome 30.6 CRP KNG1 MTHFR SERPINE1

Graphical network of the top 20 diseases related to Vascular Disease:



Diseases related to Vascular Disease
Sources

Symptoms & Phenotypes for Vascular Disease

About this section

UMLS symptoms related to Vascular Disease:


angina pectoris, edema, chest pain, flushing, leg cramps, warm skin, vein pain

MGI Mouse Phenotypes related to Vascular Disease:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.06 ACE APOE CRP EDN1 INS MMP9
2 homeostasis/metabolism MP:0005376 9.93 ACE APOE CRP EDN1 INS MMP9
3 digestive/alimentary MP:0005381 9.8 APOE EDN1 INS MMP9 NOS3 VEGFA
4 liver/biliary system MP:0005370 9.56 ACE APOE INS MTHFR NOS3 SELP
5 renal/urinary system MP:0005367 9.28 ACE APOE EDN1 INS MMP9 NOS3
Sources

Drugs & Therapeutics for Vascular Disease

About this section

PubMedHealth treatment related to Vascular Disease: 64

Aortic aneurysms are treated with medicines and surgery. Small aneurysms that are found early and aren’t causing symptoms may not need treatment. Other aneurysms need to be treated.The goals of treatment may include:Preventing the aneurysm from growingPreventing or reversing damage to other body structuresPreventing or treating a rupture or dissectionAllowing you to continue doing your normal daily activitiesTreatment for an aortic aneurysm is based on its size. Your doctor may recommend routine testing to make sure an aneurysm isn't getting bigger. This method usually is used for aneurysms that are smaller than 5 centimeters (about 2 inches) across.How often you need testing (for example, every few months or every year) is based on the size of the aneurysm and how fast it's growing. The larger it is and the faster it's growing, the more often you may need to be checked.

Drugs for Vascular Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1309)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Testosterone undecanoate Approved, Investigational Phase 4,Phase 2 5949-44-0
2
Testosterone enanthate Approved Phase 4,Phase 2 315-37-7 9416
3
Methyltestosterone Approved Phase 4,Phase 2 58-18-4 6010
4
Testosterone Approved, Experimental, Investigational Phase 4,Phase 2 58-22-0, 481-30-1 10204 6013
5
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 33069-62-4 36314
6
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-78-2 2244
7
Ramipril Approved Phase 4,Phase 3,Phase 2,Not Applicable 87333-19-5 5362129
8
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 120202-66-6, 113665-84-2 60606
9
Simvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 79902-63-9 54454
10
Ustekinumab Approved, Investigational Phase 4 815610-63-0
11
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 657-24-9 14219 4091
12
Exenatide Approved, Investigational Phase 4 141758-74-9 15991534
13
Famotidine Approved Phase 4,Phase 2 76824-35-6 3325
14
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 51-45-6 774
15
Esomeprazole Approved, Investigational Phase 4,Phase 1 161796-78-7, 161973-10-0, 119141-88-7 9568614 4594
16
Enalapril Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 75847-73-3 40466924 5362032
17
Enalaprilat Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 76420-72-9 6917719
18
Iodine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 7553-56-2 807
19
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
20
Teicoplanin Approved, Investigational Phase 4 61036-62-2
21
Metronidazole Approved Phase 4,Not Applicable 443-48-1 4173
22
Povidone Approved Phase 4,Early Phase 1 9003-39-8
23
Povidone-iodine Approved Phase 4,Early Phase 1,Not Applicable 25655-41-8
24
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 55-56-1 2713 9552079
25
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
26
Sevelamer Approved Phase 4 52757-95-6
27
Cilostazol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 73963-72-1 2754
28
Ticagrelor Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 274693-27-5 9871419
29
Pravastatin Approved Phase 4,Phase 3,Phase 2,Not Applicable 81093-37-0 54687
30
Manidipine Approved, Investigational Phase 4,Phase 3 89226-50-6
31
Amlodipine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 88150-42-9 2162
32
Midodrine Approved Phase 4,Phase 3 133163-28-7, 42794-76-3 4195
33
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 299-42-3 9294
34
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 59-42-7 6041
35
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 90-82-4 7028
36
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1491-59-4 4636
37
Norepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-41-2 439260
38
Remifentanil Approved Phase 4,Phase 3,Not Applicable 132875-61-7 60815
39
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
40
Nifedipine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 21829-25-4 4485
41
Ondansetron Approved Phase 4,Phase 2,Phase 3,Not Applicable 99614-02-5 4595
42
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 10102-43-9 145068
43
Sevoflurane Approved, Vet_approved Phase 4,Not Applicable 28523-86-6 5206
44
Desflurane Approved Phase 4,Not Applicable 57041-67-5 42113
45
Bisoprolol Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 66722-44-9 2405
46
Telmisartan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 144701-48-4 65999
47
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 58-93-5 3639
48
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 11128-99-7, 68521-88-0, 4474-91-3 172198
49
Amiloride Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2609-46-3, 2016-88-8 16231
50
Captopril Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 62571-86-2 44093

Interventional clinical trials:

(show top 50) (show all 10000)
# Name Status NCT ID Phase Drugs
1 Testosterone for Peripheral Vascular Disease Unknown status NCT00504712 Phase 4 Testosterone;0.9% saline
2 The Efficacy Assessment of Intravitreal Injection of Conbercept in Patients With Polypoidal Choroidal Vasculopathy (PCV) Unknown status NCT03159884 Phase 4 Conbercept
3 Intravitreal Aflibercept for Neovascular Polypoidal Choroidal Vasculopathy (RIVAL Trial) Unknown status NCT02092532 Phase 4 Rescue Intravitreal Aflibercept Injection
4 Paclitaxel Eluting Balloon and Conventional Balloon for In-Stent Restenosis of the Superficial Femoral Artery Unknown status NCT01083394 Phase 4
5 Efficacy Study of Stenting, Paclitaxel Eluting Balloon or Atherectomy to Treat Peripheral Artery Disease Unknown status NCT00986752 Phase 4
6 Optimized Strategy for Diabetic Patients With Critical Limb Ischemia(Part II) (DCLI-II) Unknown status NCT01173094 Phase 4
7 Optimized Strategy for Diabetic Patients With Critical Limb Ischemia(Part I) Unknown status NCT01171703 Phase 4
8 Comparison of Stent and Prothesis Bypass in Superficial Femoral Artery Unknown status NCT01147419 Phase 4
9 Ramipril and Clopidogrel in Oxidative Stress, Vascular Inflammation and Endothelial Dysfunction in Type 2 Diabetes and Diabetic Nephropathy Unknown status NCT01743014 Phase 4 Ramipril;Clopidogrel
10 Living With Statins - Interventional Exercise Study Unknown status NCT02796378 Phase 4 Training+Simvastatin+Q10-placebo;Training+Simvastatin-placebo+Q10-placebo;Training+Simvastatin+Q10
11 Early Warning and Optimization Strategy in Carotid Endarterectomy Unknown status NCT01210937 Phase 4
12 Study Effects of Ginkgo Biloba Extract on Endothelial Cell Function and Genetic Effects on the Response to Ginkgo Biloba Extract in Diabetic Patients With Stable Coronary Artery Disease Unknown status NCT01038050 Phase 4 Ginkgo Biloba Extract (GBE)
13 The Difference of Microparticles in Patients With Psoriasis Vulgaris Who Received Stelara(Ustekinumab) Unknown status NCT02693470 Phase 4 Ustekinumab
14 Evaluate the Effect of Exenatide Treatment on Coronary Artery Endothelial Function Unknown status NCT02584075 Phase 4 Byetta (Exenatide);Glucophage ( Metformin Hydrochloride)
15 Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer Dyspepsia Unknown status NCT00978159 Phase 4 esomeprazole;Famotidine
16 LDL-C Lowering Efficacy and Safety of Rosuvastatin 20 mg/Day to10 mg/Day in Chinese ACS(Acute Coronary Syndrome) Patients Unknown status NCT02077257 Phase 4 Rosuvastatin
17 Anti-Hypertensive Agent (ACEi) and Heart Function Improvement in Association With Rho Kinase Activity Changes in Human Unknown status NCT01069042 Phase 4 Enalapril
18 The Amputation Surgical Site Infection Trial (ASSIT) Unknown status NCT02018094 Phase 4 Co-amoxiclav;Iodine;Metronidazole;Chlorhexidine;Teicoplanin;Clindamycin
19 Graz Study on the Risk of Atrial Fibrillation Unknown status NCT01461434 Phase 4
20 How Bone is Made in Children Receiving Dialysis Unknown status NCT01799317 Phase 4 Vitamin D2
21 Safety and Efficacy Study of OmniWave Endovascular System to Treat Deep Vein Thrombosis Unknown status NCT00640731 Phase 4
22 Lovaza Mechanisms of Action Unknown status NCT01301794 Phase 4
23 Residual Platelet Activity In Advanced Peripheral Artery Disease Unknown status NCT01627431 Phase 4 Acetylsalicylic acid;Clopidogrel
24 Platelets Induced Vasodilation, in Vitro and in Vivo Study Unknown status NCT00152646 Phase 4 placebo, aspirine, clopidogrel
25 Paclitaxel Eluting Stent or Exercise for Thigh Atherosclerosis Unknown status NCT02033135 Phase 4
26 Efficacy of Self-Expanding Nitinol S.M.A.R.T CONTROL Stent Versus Life Stent For The Atherosclerotic Femoro-Popliteal Arterial Disease Unknown status NCT01653600 Phase 4
27 Cilostazol Versus Aspirin for Primary Prevention of Atherosclerotic Events Unknown status NCT00886574 Phase 4 Cilostazol;Aspirin
28 Bedside Testing of CYP2C19 Gene for Treatment of Patients With PCI With Antiplatelet Therapy Unknown status NCT01823185 Phase 4 clopidogrel;Ticagrelor or prasugrel
29 Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy Unknown status NCT01023373 Phase 4 Medical treatment
30 The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoris Unknown status NCT01325818 Phase 4 pravastatin, rosuvastatin
31 Manidipine Versus Amlodipine in Patients With Hypertension Unknown status NCT03106597 Phase 4 Manidipine 20mg;Amlodipine 10mg
32 Minimization of Intradialytic Hypotension Using Cardiography-Guided Intervention Unknown status NCT03080441 Phase 4 Midodrine
33 Norepinephrine and Phenylephrine for Maternal Cardiac Output During Spinal Anesthesia for Elective Cesarean Delivery Unknown status NCT02969239 Phase 4 Norepinephrine;Phenylephrine
34 Effect of Controlled Hypotension on Cerebral Oxygen Saturation Unknown status NCT02967029 Phase 4 Esmolol Hydrochloride;Remifentanil Hydrochloride
35 Nifedipine GITS and Amlodipine Besylate on Recovery of Blood Pressure Rhythm and Arterial Stiffness Unknown status NCT02940548 Phase 4 Nifedipine GITS;Amlodipine besylate
36 Reduction in Spinal-induced Hypotension With Ondansetron in Parturients Undergoing Caesarean Section Unknown status NCT02913768 Phase 4 Ondansetron;Normal saline
37 L-arginine Treatment in Mild Hypertension Unknown status NCT02894723 Phase 4
38 Antihypertensive Treatment in Masked Hypertension for Target Organ Protection Unknown status NCT02893358 Phase 4 Allisartan Isoproxil;Placebo
39 Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension Unknown status NCT02834845 Phase 4 Sevoflurane;Desflurane
40 The Effect of the Timing of Colloid and Crystalloid Infusions on Postspinal Hypotension After Spinal Anesthesia for Caesarian Section Unknown status NCT02680678 Phase 4
41 Multifactorial Intervention on Cardiovascular Risk Factors in Subjects With Peripheral Arterial Disease Unknown status NCT00144937 Phase 4 Stepwise therapy for dyslipidemia, hypertension and diabetes
42 BRAVE Study With Uncontrolled Essential Hypertension (BRAVE Study) Unknown status NCT02398929 Phase 4 Bisoprolol 2.5 mg;Placebo
43 Colloid Preload Versus Colloid Coload During Cesarean Deliveries Unknown status NCT02393196 Phase 4 hydroxyethyl starch (% 6 HES 130/0.4) (Voluven®);hydroxyethyl starch (%6 HES 130/0.4) (Voluven®)
44 INTERVENCION Trial Unknown status NCT02373163 Phase 4 Hydrochlorothiazide;Amlodipine;Telmisartan
45 Comparison of Single and Combination Diuretics in Low-Renin Hypertension Unknown status NCT02351973 Phase 4 Hydrochlorthiazide;Amiloride;Hydrochlorthiazide and Amiloride
46 The Efficacy of a Combination of Telmisartan/S-Amlodipine Compared With Telmisartan Monotherapy Unknown status NCT02231788 Phase 4 Telminuvo®Tab. 40/2.5mg;Telmitrend®Tab. 80mg
47 Treatment of Hypertension in Tibetan Adult Population Unknown status NCT02217852 Phase 4 Nitrendipine;Hydrochlorothiazide;Captopril,Hydrochlorothiazide;Beijing hypotensive No.0
48 Treatment of HYpertension: Morning Versus Evening Unknown status NCT02214498 Phase 4 Enalapril/hydrochlorothiazide;Placebo
49 The Short-term Efficacy of Gastrodia and Uncaria Drink in Treating Hypertension Unknown status NCT02156024 Phase 4 Gastrodia and Uncaria Drink
50 Chlorthalidone and HCTZ Impacts on Platelet Activation Unknown status NCT02100462 Phase 4 Chlorthalidone 12.5 mg;Hydrochlorothiazide 25 mg;Aspirin 81 mg

Search NIH Clinical Center for Vascular Disease

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: vascular diseases

Sources

Genetic Tests for Vascular Disease

About this section
Sources

Anatomical Context for Vascular Disease

About this section

MalaCards organs/tissues related to Vascular Disease:

42
Endothelial, Testes, Kidney, Eye, Brain, Heart, Bone Marrow
Sources

Publications for Vascular Disease

About this section

Articles related to Vascular Disease:

(show top 50) (show all 5730)
# Title Authors Year
1
Long Non-Coding RNA in Vascular Disease and Aging. ( 30893946 )
2019
2
Vascular Disease and Dementia: Lipoprotein(a) as a Neglected Link. ( 31096303 )
2019
3
Correction to: Sex and Gender Differences in Ischemic Heart Disease: Endocrine Vascular Disease Approach (EVA) Study Design. ( 30756360 )
2019
4
Pulmonary arterial compliance is a useful predictor of pulmonary vascular disease in congenital heart disease. ( 30225809 )
2019
5
Cerebrospinal Fluid Biomarkers in Idiopathic Normal Pressure Hydrocephalus versus Alzheimer's Disease and Subcortical Ischemic Vascular Disease: A Systematic Review. ( 30741681 )
2019
6
Automated CT quantification methods for the assessment of interstitial lung disease in collagen vascular diseases: A systematic review. ( 30777211 )
2019
7
Outcomes of minor amputations in patients with peripheral vascular disease over a 10-year period at a tertiary care institution. ( 30157719 )
2019
8
Outcomes of Wound Healing and Limb Loss After Transmetatarsal Amputation in the Presence of Peripheral Vascular Disease. ( 30583781 )
2019
9
Guidelines for Peripheral Vascular Disease: Where Is the Evidence? ( 30608871 )
2019
10
Strength of Evidence Underlying the American Heart Association/American College of Cardiology Guidelines on Endovascular and Surgical Treatment of Peripheral Vascular Disease. ( 30608884 )
2019
11
Hospital Discharge Teaching for Patients with Peripheral Vascular Disease. ( 30736938 )
2019
12
Four-Limb Blood Pressure Measurement with an Oscillometric Device: a Tool for Diagnosing Peripheral Vascular Disease. ( 30747289 )
2019
13
Outcomes in patients with peripheral vascular disease following percutaneous coronary intervention. ( 30790432 )
2019
14
Noncontrast Magnetic Resonance Angiography for the Diagnosis of Peripheral Vascular Disease. ( 31088154 )
2019
15
Vascular Teams in Peripheral Vascular Disease. ( 31097169 )
2019
16
Translational research in retinal vascular disease. An approach. ( 30801973 )
2019
17
Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis. ( 30847414 )
2019
18
A comparative study on the effect of argan oil versus fish oil on risk factors for cardio-vascular disease in high-fat-fed rats. ( 30153577 )
2019
19
Impact of Vascular Disease, Amputation Level, and the Mismatch Between Balance Ability and Balance Confidence in a Cross-Sectional Study of the Likelihood of Falls Among People With Limb Loss: Perception Versus Reality. ( 30188335 )
2019
20
Early Pulmonary Vascular Disease in Preterm Infants Is Associated with Late Respiratory Outcomes in Childhood. ( 30303395 )
2019
21
Pulmonary Vascular Disease in Premature Infants. Early Predictive Models of Late Respiratory Morbidity. ( 30395723 )
2019
22
Genome-edited MSCs that express GCP-2 and SDF-1α might be a novel therapeutic strategy for the treatment of ischemic vascular disease. ( 30449331 )
2019
23
Simultaneous double arm automated blood pressure measurement for the screening of subjects with potential vascular disease: a community study. ( 30460865 )
2019
24
BIOMECHANICAL FORCES AND OXIDATIVE STRESS: IMPLICATIONS FOR PULMONARY VASCULAR DISEASE. ( 30623676 )
2019
25
Vegetable diversity in relation with subclinical atherosclerosis and 15-year atherosclerotic vascular disease deaths in older adult women. ( 30656478 )
2019
26
Trained immunity and diabetic vascular disease. ( 30659160 )
2019
27
HDAC9 complex inhibition improves smooth muscle-dependent stenotic vascular disease. ( 30674723 )
2019
28
Alterations of White Matter Integrity in Subcortical Ischemic Vascular Disease with and Without Cognitive Impairment: a TBSS Study. ( 30685818 )
2019
29
A study on role and mechanism of TLR4/NF-κB pathway in cognitive impairment induced by cerebral small vascular disease. ( 30689560 )
2019
30
Metabolomics as an Innovative Tool for a Personalised Approach to Vascular Disease. ( 30718034 )
2019
31
Osteopontin in Vascular Disease. ( 30727754 )
2019
32
The pathophysiological basis of vascular disease. ( 30755702 )
2019
33
Epigenetic Mechanisms in Monocytes/Macrophages Regulate Inflammation in Cardiometabolic and Vascular Disease. ( 30760015 )
2019
34
Insulin resistance is associated with subclinical vascular disease in humans. ( 30788044 )
2019
35
Small GTPases and Their Role in Vascular Disease. ( 30791562 )
2019
36
Effect of patent ductus arteriosus on pulmonary vascular disease. ( 30811787 )
2019
37
Assessement of Vascular Event Prevention and Cognitive Function Among Older Adults With Preexisting Vascular Disease or Diabetes: A Secondary Analysis of 3 Randomized Clinical Trials. ( 30821829 )
2019
38
The Effectiveness of Exercise on Cognitive Performance in Individuals with Known Vascular Disease: A Systematic Review. ( 30832238 )
2019
39
Adipokine Dysregulation and Insulin Resistance with Atherosclerotic Vascular Disease: Metabolic Syndrome or Independent Sequelae? ( 30835048 )
2019
40
miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease. ( 30847421 )
2019
41
Altered functional connectivity in patients with subcortical ischemic vascular disease: A resting-state fMRI study. ( 30910630 )
2019
42
Diagnostic accuracy and efficiency of combined acquisition of low-dose time-resolved and single-phase high-resolution contrast-enhanced magnetic resonance angiography in a single session for pre-angiographic evaluation of spinal vascular disease. ( 30921365 )
2019
43
Spinal vascular disease: a neglected cause of myelopathy. ( 30948558 )
2019
44
Altered static and dynamic functional network connectivity in Alzheimer's disease and subcortical ischemic vascular disease: shared and specific brain connectivity abnormalities. ( 30950567 )
2019
45
Combustion Particle-Induced Changes in Calcium Homeostasis: A Contributing Factor to Vascular Disease? ( 30955163 )
2019
46
Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China. ( 30955975 )
2019
47
Porto-sinusoidal vascular disease: proposal and description of a novel entity. ( 30957754 )
2019
48
Modulating Adaptive Immunity in Vascular Disease: CD4 to the Fore. ( 30975300 )
2019
49
Baseline fasting plasma insulin levels predict risk for major adverse cardiovascular events among patients with diabetes and high-risk vascular disease: Insights from the ACCELERATE trial. ( 31014095 )
2019
50
Risk of vascular disease and cognitive function in very old adults. ( 31018885 )
2019