Aliases & Classifications for Vein Disease

Summaries for Vein Disease

Disease Ontology : 12 A vascular disease that is located in a vein.

MalaCards based summary : Vein Disease, also known as disorder of vein, is related to varicose veins and portal vein thrombosis, and has symptoms including vein pain An important gene associated with Vein Disease is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Lidocaine and Rivaroxaban have been mentioned in the context of this disorder. Affiliated tissues include a vein, skin and bone, and related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for Vein Disease

Diseases related to Vein Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 171)
# Related Disease Score Top Affiliating Genes
1 varicose veins 32.4 F2 F5 MTHFR SERPINC1
2 portal vein thrombosis 31.3 AFP F2 F5 MTHFR SERPINC1
3 thrombophlebitis 28.7 F2 F5 F8 MTHFR PLAT SERPINC1
4 pulmonary embolism 28.3 ALB F2 F3 F5 MTHFR PLAT
5 thrombosis 27.8 F2 F3 F5 MTHFR PLAT PROC
6 venous insufficiency 11.0
7 paracetamol poisoning 11.0 F2 F5
8 inferior vena cava interruption 11.0 F5 MTHFR
9 antipyrine metabolism 10.9 ALB F2
10 non-a-e hepatitis 10.9 ALB F2
11 mesenteric vascular occlusion 10.9 F2 MTHFR
12 amaurosis fugax 10.9 F5 MTHFR
13 neonatal stroke 10.9 MTHFR PROC
14 livedoid vasculopathy 10.8 F2 F5 MTHFR
15 hemoglobin e disease 10.8 F2 F5
16 cryptogenic cirrhosis 10.8 F2 F5 MTHFR
17 porencephaly 10.8 F2 F5 MTHFR
18 ischemic neuropathy 10.8 F2 MTHFR
19 sticky platelet syndrome 10.8 F5 SERPINC1
20 abdominal tuberculosis 10.8 ALB F2
21 arteritic anterior ischemic optic neuropathy 10.8 F2 F5 MTHFR
22 prothrombin deficiency, congenital 10.8 F2 F5 SERPINC1
23 ischemic colitis 10.8 F2 F5 SERPINC1
24 sneddon syndrome 10.7 F2 F5 SERPINC1
25 cerebral palsy 10.7 F2 F5 MTHFR
26 acute liver failure 10.7 ALB F2 F5
27 osteonecrosis 10.7 F2 MTHFR SERPINC1
28 meningococcemia 10.7 F5 PROC SERPINC1
29 nutritional deficiency disease 10.7 ALB F2 MTHFR
30 fibrinolytic defect 10.7 PLAT SERPINC1
31 hypersplenism 10.7 ALB F2 SERPINC1
32 kwashiorkor 10.7 ALB F2
33 qualitative platelet defect 10.6 F2 F3
34 hepatic tuberculosis 10.6 ALB F2
35 heparin-induced thrombocytopenia 10.6 F3 SERPINC1
36 intermittent claudication 10.6 ALB F2 SERPINC1
37 homocystinuria 10.6 F5 MTHFR SERPINC1
38 burns 10.6 ALB SERPINC1
39 alpha-2-plasmin inhibitor deficiency 10.6 F2 PLG SERPINC1
40 conjugate gaze palsy 10.6 F3 PLG
41 anterior spinal artery syndrome 10.6 F2 PLG SERPINC1
42 severe pre-eclampsia 10.6 ALB F5 SERPINC1
43 spinal cord infarction 10.6 F2 F5 MTHFR SERPINC1
44 sudden sensorineural hearing loss 10.6 F2 F5 MTHFR SERPINC1
45 argentine hemorrhagic fever 10.6 PLAT SERPINC1
46 antithrombin iii deficiency 10.6 F2 F5 MTHFR SERPINC1
47 central retinal vein occlusion 10.5 F2 F5 MTHFR SERPINC1
48 patent foramen ovale 10.5 F2 F5 MTHFR SERPINC1
49 placental abruption 10.5 F2 F5 MTHFR SERPINC1
50 ischemic optic neuropathy 10.5 F2 F5 MTHFR SERPINC1

Graphical network of the top 20 diseases related to Vein Disease:



Diseases related to Vein Disease

Symptoms & Phenotypes for Vein Disease

UMLS symptoms related to Vein Disease:


vein pain

MGI Mouse Phenotypes related to Vein Disease:

46 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.47 EVL ALB BLOC1S2 F2 ADAM17 EPAS1
2 mortality/aging MP:0010768 10.38 EVL ALB BLOC1S2 F2 ADAM17 EPAS1
3 cardiovascular system MP:0005385 10.36 EVL BLOC1S2 ADAM17 EPAS1 PARVA PLAT
4 growth/size/body region MP:0005378 10.3 ADAM17 EPAS1 F3 PARVA F5 F2
5 hematopoietic system MP:0005397 10.29 EVL BLOC1S2 ADAM17 EPAS1 PLAT F2
6 behavior/neurological MP:0005386 10.26 AFP EVL BLOC1S2 F3 F5 F2
7 immune system MP:0005387 10.22 EVL ADAM17 EPAS1 F3 F2 F8
8 nervous system MP:0003631 10.2 EVL BLOC1S2 F2 ADAM17 EPAS1 PLAT
9 embryo MP:0005380 10.19 BLOC1S2 ADAM17 EPAS1 PARVA F5 F2
10 liver/biliary system MP:0005370 10.09 AFP ALB BLOC1S2 EPAS1 F5 SERPINC1
11 integument MP:0010771 10.06 ADAM17 F3 F5 F2 MTHFR PLG
12 muscle MP:0005369 9.97 ALB ADAM17 EPAS1 F3 PARVA PROC
13 normal MP:0002873 9.86 EVL ALB ADAM17 F3 F2 RAB3D
14 reproductive system MP:0005389 9.76 AFP ADAM17 F8 F2 MTHFR PLG
15 respiratory system MP:0005388 9.56 ADAM17 EPAS1 F2 F3 PROC PLAT
16 vision/eye MP:0005391 9.23 BLOC1S2 ADAM17 EPAS1 F3 MTHFR PLG

Drugs & Therapeutics for Vein Disease

Drugs for Vein Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 90)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
2
Rivaroxaban Approved Phase 4,Phase 3 366789-02-8
3
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
4
Sodium Tetradecyl Sulfate Approved, Investigational Phase 4,Not Applicable 1191-50-0, 139-88-8 14492 5248
5
Polidocanol Approved Phase 4 9002-92-0
6
Racepinephrine Approved Phase 4 329-65-7 838
7
Serine Approved, Nutraceutical Phase 4,Phase 3 56-45-1 5951
8 Aminaftone Phase 4
9 Coagulants Phase 4,Phase 3
10 Hemostatics Phase 4,Phase 3
11 Pharmaceutical Solutions Phase 4,Not Applicable
12 Anticoagulants Phase 4,Phase 3
13 Anti-Inflammatory Agents Phase 4,Not Applicable
14
protease inhibitors Phase 4,Phase 3
15 Respiratory System Agents Phase 4
16 Central Nervous System Depressants Phase 4
17 Adrenergic Agents Phase 4
18 Adrenergic Agonists Phase 4
19 Adrenergic alpha-Agonists Phase 4
20 Serine Proteinase Inhibitors Phase 4,Phase 3
21 Adrenergic beta-Agonists Phase 4
22 Mydriatics Phase 4
23 Sodium Channel Blockers Phase 4
24 Neurotransmitter Agents Phase 4
25 HIV Protease Inhibitors Phase 4,Phase 3
26 Anesthetics Phase 4
27 Anesthetics, Local Phase 4
28 Diuretics, Potassium Sparing Phase 4
29 Vasoconstrictor Agents Phase 4
30 Anti-Arrhythmia Agents Phase 4
31 Anti-Asthmatic Agents Phase 4
32 Peripheral Nervous System Agents Phase 4
33 Epinephryl borate Phase 4
34 Factor Xa Inhibitors Phase 4,Phase 3
35 Antithrombin III Phase 4,Phase 3
36 Autonomic Agents Phase 4
37 Antithrombins Phase 4,Phase 3
38 Bronchodilator Agents Phase 4
39 Calamus Nutraceutical Phase 4,Not Applicable
40
Warfarin Approved Phase 3 81-81-2 6691 54678486
41
Heparin Approved, Investigational Phase 3,Not Applicable 9005-49-6 772 46507594
42 Nadroparin Approved, Investigational Phase 3 9041-08-1
43
Tinzaparin Approved Phase 3 9005-49-6, 9041-08-1 25244225
44
Dalteparin Approved Phase 3 9005-49-6
45
Enoxaparin Approved Phase 3 9005-49-6 772
46
Citric Acid Approved, Nutraceutical, Vet_approved Phase 3 77-92-9 311
47 calcium heparin Phase 3,Not Applicable
48 Fibrinolytic Agents Phase 3
49 Heparin, Low-Molecular-Weight Phase 3
50 Tin Fluorides Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 70)
# Name Status NCT ID Phase Drugs
1 Compression Aided Management of Edema in Patients With C3 Venous Disease Unknown status NCT00766974 Phase 4
2 Efficacy on Pain Following a Procedure for Injecting Sclerotherapeutic Foam Into the Great Saphenous Vein Completed NCT01368159 Phase 4
3 ClosureFAST vs. Laser Ablation for the Treatment of GSV Disease: A Multicenter, Single-Blinded, Randomized Study. Completed NCT00509392 Phase 4
4 Iliac Vein Stenting in Advanced Chronic Venous Insufficiency Completed NCT02149212 Phase 4 Phlebotonic
5 Rivaroxaban With Diosmine in Long-term Treatment of DVT Recruiting NCT03413618 Phase 4 Rivaroxaban;Diosmin
6 Laser Ablation Versus Mechanochemical Ablation Trial Recruiting NCT02627846 Phase 4 Lidocaine with 1:200,000 epinephrine solution;Lidocaine with 1:200,000 epinephrine solution;Sodium Bicarbonate;Sodium Tetradecyl Sulphate
7 Study of Antiinflammatory Effects of Detralex (Daflon) Enrolling by invitation NCT01654016 Phase 4 Detralex
8 Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs Withdrawn NCT02988063 Phase 4 Polidocanol Endovenous Microfoam (PEM)
9 RCT Comparing Standard Cannula Delivered FS, UGFS and ClariVein® in the Management of SVI Withdrawn NCT02010437 Phase 4 Sodium Tetradecyl Sulphate (STS)
10 Efficacy and Safety of Diosmin 600mg Versus Placebo on Painful Symptomatology in Patients With Chronic Venous Disease of Lower Limbs Completed NCT01532882 Phase 3 Diosmin;Placebo
11 The Influence of Compression Stockings on Skin's Barrier Function at Patients With Chronic Venous Disease Completed NCT00196443 Phase 2, Phase 3
12 Efficacy on Volume Reduction and Tolerance of Progressiv' Medical Compressive Therapy (MCT) V0322 BC in Patients With Chronic Venous Oedema Completed NCT01402921 Phase 3
13 Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis Completed NCT00790335 Phase 3 Recombinant tissue plasminogen activator (rt-PA)
14 The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome Completed NCT00143598 Phase 3
15 Randomized Controlled Trial of Anticoagulation vs. Placebo for a First Symptomatic Isolated Distal Deep-vein Thrombosis (IDDVT) Completed NCT00421538 Phase 3 nadroparine calcium;Placebo
16 Crenobalneotherapy in the Treatment of Chronic Venous Insufficiency Completed NCT01956318 Phase 3
17 PRP ULCERAS: Clinical Trial Phase III Active, not recruiting NCT02213952 Phase 3 Platelet-Rich Plasma
18 Study of Combined Topical Growth Factor and Protease Inhibitor in Chronic Wound Healing Not yet recruiting NCT02845466 Phase 3
19 Calcium Dobesilate for Chronic Venous Wounds Suspended NCT00979836 Phase 3 Calcium Dobesilate
20 Rivaroxaban Anticoagulation for Superficial Vein Thrombosis Suspended NCT02123524 Phase 3 Rivaroxaban;Placebo
21 Great Saphenous Vein Electrocoagulation Unknown status NCT02139085 Phase 2
22 Non-Healing Ulcers Without Critical Limb Ischemia Unknown status NCT01666093 Phase 2
23 Treatment of Claudication With a Peristaltic Pulse Pneumatic Device Unknown status NCT01007604 Phase 2
24 Surface NeuroMuscular Electrical Stimulation in the Treatment of Chronic Venous Leg Ulcers Completed NCT01801891 Phase 2
25 Cooling Lower Leg Skin to Prevent Venous Leg Ulcers in Patients With Poor Vein Circulation Completed NCT01509599 Phase 1, Phase 2
26 Physical Conditioning in Management of Chronic Venous Insufficiency Completed NCT00013273 Phase 2
27 Mesoglycan (Prisma®) Versus Placebo in Secondary Prevention of the Superficial Venous Thrombosis Recruiting NCT03428711 Phase 2 Mesoglycan Oral Tablet;Placebo Oral Tablet
28 EXPLORATORY ASSESSMENT OF THE EFFECTS OF CYCLO 3 ® FORT (Ruscus Extract, Hesperidin Methyl Chalcone, Ascorbic Acid) OR MICRONISED PURIFIED FLAVONOID FRACTION ON VASCULAR PARAMETERS AND BIOMARKERS IN WOMEN SUFFERING FROM CHRONIC VENOUS DISEASE (CEAP C2 OR Withdrawn NCT02907320 Phase 2 CYCLO 3 ® FORT;MPFF;placebo CYCLO 3 ® FORT;placebo MPFF
29 Elastic Compression in Chronic Venous Disease Unknown status NCT02641600 Not Applicable
30 Venous Pressure Measurement of the Great Saphenous Vein Using Controlled Compression Ultrasound in Healthy Persons and Patients With Chronic Venous Disease as a New Non Invasive Method for Investigation of the Pathophysiology in Primary Varicose Veins Unknown status NCT01000909
31 Prevalence of Onychodystrophy in Patients With Chronic Venous Disease of the Lower Limbs Completed NCT02731222
32 Evaluating the Occurence of New and Progression of Existing Peripheral Venous Disease in Leg Veins Completed NCT00508079
33 Prevalence of MTHFR Polymorphisms in Venous Disease Completed NCT01993914
34 Estrogen Receptors and Chronic Venous Disease Completed NCT02558426
35 FOAM-study, Cost Minimization Study Comparing Surgery Versus Duplex Guided Foam Sclerotherapy of Varicose Veins Completed NCT01103258 Not Applicable
36 Epidemiology of Venous Disease Completed NCT00005392
37 Venous Insufficiency and Neuromuscular Stimulation Completed NCT02137499 Not Applicable
38 Pen Torch Transillumination: Shedding Light on Difficult Venepuncture Completed NCT02570568 Not Applicable
39 Copper Impact on Venous Insufficiency and Lipodermatosclerosis Completed NCT03283800 Not Applicable
40 LLLT of Trophic Ulcers of Lower Extremities and Chronic Venous Insufficiency Completed NCT03104985 Not Applicable
41 Manual Lymphatic Drainage in Chronic Venous Insufficiency: a Randomized Controlled Trial Completed NCT01899482 Not Applicable
42 Evaluating the Relationship Between Blood Clotting Disorders, Inflammation, and Obesity in Individuals With Venous Disorders and Post-Thrombotic Syndrome Completed NCT00395265
43 Compression Therapy Versus Surgery in the Treatment of Superficial Venous Reflux Completed NCT01701661 Not Applicable
44 Non-Invasive Management of Chronic Venous Insufficiency Completed NCT00950378
45 Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator Veins Completed NCT00565604 Not Applicable
46 ClosureFAST - Radiofrequency Great Saphenous Vein Treatment Completed NCT00842296 Not Applicable
47 New Genetic Mutations in Thromboembolic Venous Disease Idiopathic. Study "FIT GENETIQUE". Recruiting NCT02841085
48 Ongoing Registry of Treatment of Chronic Venous Diseases Recruiting NCT03035747
49 Effect of Standing, Lying and Stockings on Blood Bio-markers (v.1) Recruiting NCT02662127 Not Applicable
50 Haemorrhages and Thromboembolic Venous Disease of the Postpartum Recruiting NCT02443610

Search NIH Clinical Center for Vein Disease

Genetic Tests for Vein Disease

Anatomical Context for Vein Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Vein Disease:

19
A Vein

MalaCards organs/tissues related to Vein Disease:

41
Skin, Bone

Publications for Vein Disease

Articles related to Vein Disease:

(show all 41)
# Title Authors Year
1
Early clinical experience using telemedicine for the management of patients with varicose vein disease. ( 28969485 )
2017
2
CHIVA - A prospective study of a vein sparing technique for the management of varicose vein disease. ( 28431588 )
2017
3
Guidelines of the First International Consensus Conference on Endovenous Thermal Ablation for Varicose Vein Disease - ETAV Consensus Meeting 2012. ( 24534341 )
2014
4
Evaluation of apoptosis in varicose vein disease complicated by superficial vein thrombosis. ( 25007903 )
2014
5
Cost analysis of endovenous catheter ablation versus surgical stripping for treatment of superficial venous insufficiency and varicose vein disease. ( 26992979 )
2014
6
Molecular characterization and population structure of blackberry vein banding associated virus, new Ampelovirus associated with yellow vein disease. ( 24126200 )
2013
7
Platelet distribution width and saphenous vein disease in patients after CABG. Association with graft occlusion. ( 22955688 )
2013
8
One-shot scleroembolization: a new technique for the treatment of varicose veins disease of lower extremities. Preliminary results. ( 23934946 )
2013
9
A review of familial, genetic, and congenital aspects of primary varicose vein disease. ( 22896013 )
2012
10
The hemodynamic paradox as a phenomenon triggering recurrent reflux in varicose vein disease. ( 23997567 )
2012
11
The significance of upper arm cephalic vein disease in vascular access creation. ( 23020965 )
2012
12
Molecular and biological characterization of pepper yellow vein Mali virus (PepYVMV) isolates associated with pepper yellow vein disease in Burkina Faso. ( 21080204 )
2011
13
Increased vein wall apoptosis in varicose vein disease is related to venous hypertension. ( 21262580 )
2011
14
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase. ( 20881312 )
2011
15
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase. ( 21690171 )
2011
16
Endovenous laser ablation for the treatment of recurrent varicose vein disease--a single centre experience. ( 20227536 )
2010
17
Pathogenic mechanisms in varicose vein disease: the role of hypoxia and inflammation. ( 20632821 )
2010
18
Chronic venous insufficiency: current management of varicose vein disease. ( 20336886 )
2010
19
Minimally invasive vein surgery: latest options for vein disease. ( 20506452 )
2010
20
Further evidence of Mirafiori lettuce big-vein virus but not of Lettuce big-vein associated virus with big-vein disease in lettuce. ( 18944196 )
2008
21
Changes in the wall of the great saphenous vein at consecutive stages in patients suffering from chronic vein disease of the lower limbs. ( 17985316 )
2007
22
The economics of vein disease. ( 17911565 )
2007
23
A begomovirus associated with Ageratum yellow vein disease in Indonesia: evidence for natural recombination between tomato leaf curl Java virus and Ageratum yellow vein virus-[Java]. ( 17294343 )
2007
24
Surgical correction of varicose vein disease under micronized diosmin protection (results of the Russian multicenter controlled trial DEFANS). ( 18004259 )
2007
25
Selection of saphenous vein conduit in varicose vein disease. ( 16564256 )
2006
26
The histopathology of varicose vein disease. ( 17067976 )
2006
27
The DNA beta satellite component associated with ageratum yellow vein disease encodes an essential pathogenicity protein (betaC1). ( 15183051 )
2004
28
Nucleotide sequence and genomic organization of an ophiovirus associated with lettuce big-vein disease. ( 12388823 )
2002
29
Adaptation from whitefly to leafhopper transmission of an autonomously replicating nanovirus-like DNA component associated with ageratum yellow vein disease. ( 11907341 )
2002
30
Pathogenicity of a natural recombinant associated with ageratum yellow vein disease: implications for geminivirus evolution and disease aetiology. ( 11259188 )
2001
31
A unique virus complex causes Ageratum yellow vein disease. ( 10841581 )
2000
32
A nanovirus-like DNA component associated with yellow vein disease of Ageratum conyzoides: evidence for interfamilial recombination between plant DNA viruses. ( 10544139 )
1999
33
Symptomatology of vein disease. ( 7728483 )
1995
34
Unsuspected preexisting saphenous vein disease: an unrecognized cause of vein bypass failure. ( 1728668 )
1992
35
The management of varicose vein disease. ( 287952 )
1979
36
The modern treatment of varicose vein disease. ( 4520459 )
1973
37
Phlebography in varicose vein disease. ( 5014478 )
1972
38
Mesenteric vein disease. ( 13740328 )
1961
39
Yellow-vein disease of citrus and studies of interactions between yellow-vein and other viruses of citrus. ( 13843232 )
1960
40
Pulmonary embolism; its incidence, significance, and relation to antecedent vein disease. ( 18111784 )
1949
41
Pulmonary embolism; its incidence, significance, and relation to antecedent vein disease. ( 18877800 )
1948

Variations for Vein Disease

Expression for Vein Disease

Search GEO for disease gene expression data for Vein Disease.

Pathways for Vein Disease

Pathways related to Vein Disease according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.93 ALB F2 F3 F5 F8 PLAT
2
Show member pathways
12.52 F2 F3 F5 F8 PROC PROS1
3
Show member pathways
12.1 ALB F2 MTHFR PLAT PLG
4
Show member pathways
11.81 F2 F3 F5 F8 PLAT PLG
5 11.76 F3 PARVA PLG
6
Show member pathways
11.69 F2 PROC PROS1
7 11.42 F2 F3 F5 F8 PLAT PLG
8 11.25 AFP ALB F2
9 10.94 ADAM17 PLAT PLG
10 10.67 F2 PROC PROS1
11 10.57 PLAT PLG

GO Terms for Vein Disease

Cellular components related to Vein Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 9.72 ALB F2 PLG PROS1 SERPINC1
2 platelet alpha granule lumen GO:0031093 9.55 ALB F5 F8 PLG PROS1
3 Golgi lumen GO:0005796 9.54 F2 PROC PROS1
4 endoplasmic reticulum lumen GO:0005788 9.5 AFP ALB F2 F5 F8 PROC
5 extracellular space GO:0005615 9.4 AFP ALB F2 F3 F5 F8
6 extracellular region GO:0005576 10.03 AFP ALB F2 F3 F5 F8

Biological processes related to Vein Disease according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.88 AFP ALB EPAS1 F5 PROC SERPINC1
2 ER to Golgi vesicle-mediated transport GO:0006888 9.83 F2 F5 F8 PROC PROS1
3 response to hypoxia GO:0001666 9.78 ADAM17 EPAS1 MTHFR PLAT
4 platelet degranulation GO:0002576 9.72 ALB F5 F8 PLG PROS1
5 cellular protein metabolic process GO:0044267 9.7 AFP ALB F2 F5 PLG PROC
6 signal peptide processing GO:0006465 9.63 F2 PROC PROS1
7 blood coagulation GO:0007596 9.61 F2 F3 F5 F8 PLAT PLG
8 fibrinolysis GO:0042730 9.56 F2 PLAT PLG PROS1
9 blood coagulation, intrinsic pathway GO:0007597 9.54 F2 F8
10 peptidyl-glutamic acid carboxylation GO:0017187 9.54 F2 PROC PROS1
11 negative regulation of blood coagulation GO:0030195 9.52 PROC PROS1
12 regulation of blood coagulation GO:0030193 9.51 F2 SERPINC1
13 negative regulation of fibrinolysis GO:0051918 9.49 F2 PLG
14 hemostasis GO:0007599 9.23 F2 F3 F5 F8 PLG PROC

Molecular functions related to Vein Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.65 ADAM17 F2 PLAT PLG PROC
2 copper ion binding GO:0005507 9.33 ALB F5 F8
3 serine-type peptidase activity GO:0008236 9.26 F2 PLAT PLG PROC
4 serine-type endopeptidase activity GO:0004252 9.02 F2 F3 PLAT PLG PROC

Sources for Vein Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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