MCID: VNT001
MIFTS: 22

Ventilation Pneumonitis

Categories: Respiratory diseases

Aliases & Classifications for Ventilation Pneumonitis

MalaCards integrated aliases for Ventilation Pneumonitis:

Name: Ventilation Pneumonitis 12 15
Air-Conditioner and Humidifier Lung 12 74
Humidifier Lung 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11289
ICD9CM 36 495.7
SNOMED-CT 69 48347002
ICD10 34 J67.7
UMLS 74 C0155891

Summaries for Ventilation Pneumonitis

Disease Ontology : 12 An extrinsic allergic alveolitis caused by inhalation of antigens from thermophilic actinomycetes species growing in air conditioners and humidifiers. Fungi like Aureobasidium sp and Candida albicans that survive in the contaminated water in humidifiers and air conditioners are also known to cause the disease.

MalaCards based summary : Ventilation Pneumonitis, also known as air-conditioner and humidifier lung, is related to mycobacterium gordonae and bird fancier's lung. An important gene associated with Ventilation Pneumonitis is IGLL1 (Immunoglobulin Lambda Like Polypeptide 1), and among its related pathways/superpathways are Immune response NFAT in immune response and Th17 cell differentiation. Affiliated tissues include lung.

Related Diseases for Ventilation Pneumonitis

Diseases related to Ventilation Pneumonitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 mycobacterium gordonae 10.0
2 bird fancier's lung 9.9
3 farmer's lung 9.9
4 chronic graft versus host disease 9.8 CD4 TNF
5 pneumocystosis 9.8 CD4 TNF
6 melkersson-rosenthal syndrome 9.7 CD4 TNF
7 human immunodeficiency virus infectious disease 9.7 CD4 TNF
8 acquired immunodeficiency syndrome 9.7 CD4 TNF
9 viral infectious disease 9.6 CD4 TNF
10 human immunodeficiency virus type 1 9.5 CD4 TNF

Graphical network of the top 20 diseases related to Ventilation Pneumonitis:



Diseases related to Ventilation Pneumonitis

Symptoms & Phenotypes for Ventilation Pneumonitis

Drugs & Therapeutics for Ventilation Pneumonitis

Search Clinical Trials , NIH Clinical Center for Ventilation Pneumonitis

Genetic Tests for Ventilation Pneumonitis

Anatomical Context for Ventilation Pneumonitis

MalaCards organs/tissues related to Ventilation Pneumonitis:

42
Lung

Publications for Ventilation Pneumonitis

Articles related to Ventilation Pneumonitis:

# Title Authors Year
1
Difference in the phenotypes of bronchoalveolar lavage lymphocytes in patients with summer-type hypersensitivity pneumonitis, farmer's lung, ventilation pneumonitis, and bird fancier's lung: report of a nationwide epidemiologic study in Japan. ( 1902851 )
1991

Variations for Ventilation Pneumonitis

Expression for Ventilation Pneumonitis

Search GEO for disease gene expression data for Ventilation Pneumonitis.

Pathways for Ventilation Pneumonitis

Pathways related to Ventilation Pneumonitis according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.07 CD4 TNF
2
Show member pathways
12.03 CD4 TNF
3
Show member pathways
12.01 CD4 TNF
4
Show member pathways
11.99 CD4 TNF
5
Show member pathways
11.55 CD4 TNF
6 11.47 CD4 TNF
7 11.35 CD4 TNF
8 11.22 CD4 TNF
9 11.13 CD4 TNF
10 11.01 CD4 TNF
11 10.52 CD4 IGLL1
12 10.09 CD4 TNF

GO Terms for Ventilation Pneumonitis

Cellular components related to Ventilation Pneumonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 8.96 CD4 TNF
2 external side of plasma membrane GO:0009897 8.8 CD4 IGLL1 TNF

Biological processes related to Ventilation Pneumonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.43 CD4 TNF
2 defense response to bacterium GO:0042742 9.4 IGLL1 TNF
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.37 CD4 TNF
4 leukocyte migration GO:0050900 9.32 IGLL1 TNF
5 positive regulation of protein phosphorylation GO:0001934 9.26 CD4 TNF
6 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.16 CD4 TNF
7 positive regulation of protein kinase activity GO:0045860 8.96 CD4 TNF
8 immune response GO:0006955 8.8 CD4 IGLL1 TNF

Sources for Ventilation Pneumonitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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