MCID: VNT001
MIFTS: 25

Ventilation Pneumonitis

Categories: Respiratory diseases

Aliases & Classifications for Ventilation Pneumonitis

MalaCards integrated aliases for Ventilation Pneumonitis:

Name: Ventilation Pneumonitis 12 15
Air-Conditioner and Humidifier Lung 12 73
Humidifier Lung 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11289
ICD10 33 J67.7
ICD9CM 35 495.7
SNOMED-CT 68 195990006 48347002
UMLS 73 C0155891

Summaries for Ventilation Pneumonitis

Disease Ontology : 12 An extrinsic allergic alveolitis caused by inhalation of antigens from thermophilic actinomycetes species growing in air conditioners and humidifiers. Fungi like Aureobasidium sp and Candida albicans that survive in the contaminated water in humidifiers and air conditioners are also known to cause the disease.

MalaCards based summary : Ventilation Pneumonitis, also known as air-conditioner and humidifier lung, is related to bird fancier's lung and selective igg deficiency disease. An important gene associated with Ventilation Pneumonitis is IGLL1 (Immunoglobulin Lambda Like Polypeptide 1), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include lung.

Related Diseases for Ventilation Pneumonitis

Diseases related to Ventilation Pneumonitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 162)
# Related Disease Score Top Affiliating Genes
1 bird fancier's lung 29.6 CD79A IGLL1
2 selective igg deficiency disease 10.0 CD40LG CD79A
3 c1q nephropathy 10.0 CD40LG CD79A
4 meningovascular neurosyphilis 10.0 CD40LG CD79A
5 alpha chain disease 10.0 CD40LG CD79A
6 brill-zinsser disease 10.0 CD40LG CD79A
7 exudative glomerulonephritis 10.0 CD40LG CD79A
8 cork-handlers' disease 10.0 CD40LG CD79A
9 salpingo-oophoritis 10.0 CD40LG CD79A
10 early yaws 10.0 CD40LG CD79A
11 chronic interstitial cystitis 10.0 CD40LG CD79A
12 axillary adenitis 10.0 CD40LG CD79A
13 cryofibrinogenemia 10.0 CD40LG CD79A
14 trichostrongyloidiasis 10.0 CD40LG CD79A
15 subacute bacterial endocarditis 10.0 CD40LG CD79A
16 heterophyiasis 10.0 CD40LG CD79A
17 immunoglobulin g deficiency 10.0 CD40LG CD79A
18 orbital granuloma 10.0 CD40LG CD79A
19 transient hypogammaglobulinemia of infancy 10.0 CD40LG CD79A
20 hyperglobulinemic purpura 10.0 CD40LG CD79A
21 gastroduodenitis 10.0 CD40LG CD79A
22 bacterial conjunctivitis 10.0 CD40LG CD79A
23 agammaglobulinemia, non-bruton type 10.0 CD79A IGLL1
24 heavy chain disease 10.0 CD40LG CD79A
25 ophthalmia neonatorum 10.0 CD40LG CD79A
26 immunoglobulin a deficiency 1 10.0 CD40LG CD79A
27 parotid disease 10.0 CD40LG CD79A
28 cerebral arteritis 10.0 CD40LG CD79A
29 selective immunoglobulin deficiency disease 10.0 CD40LG CD79A
30 geniculate herpes zoster 10.0 CD40LG CD79A
31 erythema elevatum diutinum 10.0 CD40LG CD79A
32 sporotrichosis 10.0 CD40LG CD79A
33 fallopian tube disease 10.0 CD40LG CD79A
34 hyperimmunoglobulin syndrome 10.0 CD40LG CD79A
35 congenital syphilis 10.0 CD40LG CD79A
36 monoclonal paraproteinemia 10.0 CD40LG CD79A
37 salpingitis 10.0 CD40LG CD79A
38 ocular toxoplasmosis 10.0 CD40LG CD79A
39 dysgammaglobulinemia 10.0 CD40LG CD79A
40 acute maxillary sinusitis 10.0 CD40LG CD79A
41 chronic polyneuropathy 10.0 CD40LG CD79A
42 spinocerebellar ataxia, autosomal recessive 10 10.0 CD40LG CD79A
43 parasitic ichthyosporea infectious disease 10.0 CD40LG CD79A
44 cd40 ligand deficiency 10.0 CD40LG CD79A
45 rhinosporidiosis 10.0 CD40LG CD79A
46 secondary syphilis 10.0 CD40LG CD79A
47 yellow nail syndrome 10.0 CD40LG CD79A
48 congenital toxoplasmosis 10.0 CD40LG CD79A
49 chorioretinitis 10.0 CD40LG CD79A
50 asymptomatic neurosyphilis 10.0 CD40LG CD79A

Graphical network of the top 20 diseases related to Ventilation Pneumonitis:



Diseases related to Ventilation Pneumonitis

Symptoms & Phenotypes for Ventilation Pneumonitis

Drugs & Therapeutics for Ventilation Pneumonitis

Search Clinical Trials , NIH Clinical Center for Ventilation Pneumonitis

Genetic Tests for Ventilation Pneumonitis

Anatomical Context for Ventilation Pneumonitis

MalaCards organs/tissues related to Ventilation Pneumonitis:

41
Lung

Publications for Ventilation Pneumonitis

Articles related to Ventilation Pneumonitis:

# Title Authors Year
1
Difference in the phenotypes of bronchoalveolar lavage lymphocytes in patients with summer-type hypersensitivity pneumonitis, farmer's lung, ventilation pneumonitis, and bird fancier's lung: report of a nationwide epidemiologic study in Japan. ( 1902851 )
1991

Variations for Ventilation Pneumonitis

Expression for Ventilation Pneumonitis

Search GEO for disease gene expression data for Ventilation Pneumonitis.

Pathways for Ventilation Pneumonitis

Pathways related to Ventilation Pneumonitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.42 CD4 CD40LG
2 11.22 CD4 CD79A
3 10.68 CD4 CD40LG
4 10.49 CD4 CD40LG CD79A IGLL1

GO Terms for Ventilation Pneumonitis

Cellular components related to Ventilation Pneumonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.92 CD4 CD40LG CD79A IGLL1

Biological processes related to Ventilation Pneumonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell receptor signaling pathway GO:0050853 9.37 CD79A IGLL1
2 T cell costimulation GO:0031295 9.32 CD4 CD40LG
3 B cell differentiation GO:0030183 9.26 CD40LG CD79A
4 positive regulation of T cell proliferation GO:0042102 9.16 CD4 CD40LG
5 immune response GO:0006955 9.13 CD4 CD40LG IGLL1
6 B cell proliferation GO:0042100 8.62 CD40LG CD79A

Sources for Ventilation Pneumonitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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