MCID: VRR004
MIFTS: 54

Verrucous Carcinoma

Categories: Cancer diseases, Oral diseases

Aliases & Classifications for Verrucous Carcinoma

MalaCards integrated aliases for Verrucous Carcinoma:

Name: Verrucous Carcinoma 12 15 17
Verrucous Squamous Cell Carcinoma 12
Verrucous Squamous Carcinoma 12
Carcinoma, Verrucous 45
Carcinoma Verrucous 56
Warty Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3737
MeSH 45 D018289
NCIt 51 C3781
SNOMED-CT 69 89906000
UMLS 74 C0206706

Summaries for Verrucous Carcinoma

Disease Ontology : 12 A squamous cell carcinoma that is a diffuse, papillary, non metastasizing, well differentiated, malignant neoplasm of epidermis or oral epithelium.

MalaCards based summary : Verrucous Carcinoma, also known as verrucous squamous cell carcinoma, is related to squamous cell papilloma and papilloma. An important gene associated with Verrucous Carcinoma is MSN (Moesin), and among its related pathways/superpathways are ERK Signaling and PI3K-Akt signaling pathway. The drugs Fluorouracil and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include skin, cervix and brain, and related phenotypes are Decreased viability with paclitaxel and cellular

Wikipedia : 77 Verrucous carcinoma (VC) is an uncommon variant of squamous cell carcinoma. This form of cancer is... more...

Related Diseases for Verrucous Carcinoma

Diseases related to Verrucous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 225)
# Related Disease Score Top Affiliating Genes
1 squamous cell papilloma 30.9 CDKN2A TP53
2 papilloma 30.5 CCND1 CDKN2A KRT10 TP53
3 vulva cancer 30.3 CDKN2A TP53
4 vulva squamous cell carcinoma 30.3 CDKN2A TP53
5 oral leukoplakia 30.2 CCND1 CDKN2A TP53
6 inverted papilloma 30.2 CCND1 CDKN2A TP53
7 oral cancer 30.2 CCND1 CDKN2A TP53
8 squamous cell carcinoma, head and neck 29.7 CCND1 CDKN2A TP53
9 retinoblastoma 29.7 CCND1 CDKN2A MDM2 TP53
10 keratoacanthoma 29.7 KRT10 TP53
11 larynx verrucous carcinoma 12.4
12 esophagus verrucous carcinoma 12.4
13 supraglottis verrucous carcinoma 12.4
14 cervical verrucous carcinoma 12.3
15 vulva verrucous carcinoma 12.3
16 glottis verrucous carcinoma 12.2
17 subglottis verrucous carcinoma 12.2
18 urethral verrucous carcinoma 12.2
19 penis non-invasive verrucous carcinoma 12.2
20 penis verrucous carcinoma 12.1
21 buschke lowenstein tumor 11.5
22 anal buschke-lowenstein tumor 11.5
23 proliferative verrucous leukoplakia 11.2
24 bladder verrucous squamous cell carcinoma 11.1
25 squamous cell carcinoma 10.6
26 penile cancer, adult 10.5
27 oral squamous cell carcinoma 10.4
28 bladder squamous cell carcinoma 10.4 CDKN2A TP53
29 ring chromosome 7 10.4 MDM2 TP53
30 zika virus infection 10.4 MDM2 TP53
31 keratinizing squamous cell carcinoma 10.4 CDKN2A TP53
32 spitz nevus 10.4 CDKN2A TP53
33 actinic cheilitis 10.4 MDM2 TP53
34 bladder carcinoma in situ 10.4 CDKN2A TP53
35 cheilitis 10.4 MDM2 TP53
36 scrotal carcinoma 10.4 CDKN2A TP53
37 thyroid lymphoma 10.4 CDKN2A TP53
38 vulvar disease 10.4 CDKN2A TP53
39 nasal cavity adenocarcinoma 10.4 CDKN2A TP53
40 sclerosing liposarcoma 10.4 MDM2 TP53
41 bartholin's gland disease 10.4 CDKN2A TP53
42 lip cancer 10.4 MDM2 TP53
43 anal squamous cell carcinoma 10.4 CDKN2A TP53
44 infiltrating angiolipoma 10.4 CDKN2A MDM2
45 megaesophagus 10.4 CDKN2A TP53
46 glycogen-rich clear cell breast carcinoma 10.4 CDKN2A TP53
47 gastric adenosquamous carcinoma 10.4 CDKN2A TP53
48 breast papillomatosis 10.4 CCND1 CDKN2A
49 anogenital venereal wart 10.4 CDKN2A TP53
50 sapho syndrome 10.3 MDM2 TP53

Graphical network of the top 20 diseases related to Verrucous Carcinoma:



Diseases related to Verrucous Carcinoma

Symptoms & Phenotypes for Verrucous Carcinoma

GenomeRNAi Phenotypes related to Verrucous Carcinoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with paclitaxel GR00293-A 8.8 KRT10 SLC2A1 TP53

MGI Mouse Phenotypes related to Verrucous Carcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.98 CCND1 CDKN2A LRIG1 MDM2 SLC2A1 TP53
2 homeostasis/metabolism MP:0005376 9.97 CCND1 CDKN2A LRIG1 MDM2 NOTCH4 SLC2A1
3 nervous system MP:0003631 9.86 CCND1 CDKN2A LRIG1 MDM2 NOTCH4 SLC2A1
4 digestive/alimentary MP:0005381 9.8 CCND1 CDKN2A LRIG1 MDM2 TP53
5 neoplasm MP:0002006 9.72 CCND1 CDKN2A LRIG1 MDM2 TP53
6 no phenotypic analysis MP:0003012 9.55 CDKN2A LRIG1 MDM2 SLC2A1 TP53
7 normal MP:0002873 9.43 CCND1 LRIG1 MDM2 MSN NOTCH4 TP53
8 skeleton MP:0005390 9.1 CCND1 CDKN2A LRIG1 MDM2 TP53 TYMP

Drugs & Therapeutics for Verrucous Carcinoma

Drugs for Verrucous Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 210)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluorouracil Approved Phase 3,Phase 2,Phase 1 51-21-8 3385
2
Cisplatin Approved Phase 3,Phase 2,Phase 1,Not Applicable 15663-27-1 2767 441203 84093
3
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
4
Docetaxel Approved, Investigational Phase 3,Phase 2,Phase 1 114977-28-5 148124
5
Cetuximab Approved Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable 205923-56-4 56842117 2333
6
Histamine Approved, Investigational Phase 3 51-45-6 774
7
Doxepin Approved, Investigational Phase 3 1668-19-5 667468 667477
8
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
9
Promethazine Approved, Investigational Phase 3 60-87-7 4927
10
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
11
Cobalt Approved, Experimental Phase 3 7440-48-4 104729
12
leucovorin Approved Phase 3,Phase 1,Phase 2 58-05-9 143 6006
13
Bleomycin Approved, Investigational Phase 3 11056-06-7 5360373
14
Vincristine Approved, Investigational Phase 3 2068-78-2, 57-22-7 5978
15
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
16
Levoleucovorin Approved, Investigational Phase 3 68538-85-2
17
Fluconazole Approved, Investigational Phase 2, Phase 3 86386-73-4 3365
18
Miconazole Approved, Investigational, Vet_approved Phase 2, Phase 3,Phase 1 22916-47-8 4189
19
Cevimeline Approved Phase 3 107233-08-9 25137844 83898
20
Panitumumab Approved, Investigational Phase 3 339177-26-3 50070211
21
Megestrol acetate Approved, Investigational, Vet_approved Phase 3 595-33-5 11683
22
Bevacizumab Approved, Investigational Phase 3,Phase 2,Phase 1 216974-75-3
23
Calcium Approved, Nutraceutical Phase 3 7440-70-2 271
24
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 1,Phase 2 59-30-3 6037
25 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
26 Neurotransmitter Agents Phase 3,Phase 2,Not Applicable
27 Liver Extracts Phase 3,Phase 2,Phase 1,Early Phase 1
28 Peripheral Nervous System Agents Phase 3,Phase 2,Not Applicable
29 Cola Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
30 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 1,Phase 2
31 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
32 Antimetabolites Phase 3,Phase 2,Phase 1
33 Antimitotic Agents Phase 3,Phase 2,Phase 1
34 Immunologic Factors Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
35 Immunosuppressive Agents Phase 3,Phase 2,Phase 1,Early Phase 1
36 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
37 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
38 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
39 Cytochrome P-450 Enzyme Inhibitors Phase 2, Phase 3
40 Anti-Infective Agents Phase 2, Phase 3,Phase 1
41 Autonomic Agents Phase 3,Phase 2,Not Applicable
42 Antineoplastic Agents, Immunological Phase 3,Phase 2,Phase 1,Not Applicable
43 Immunoglobulins Phase 3,Phase 2,Phase 1,Not Applicable
44 Antibodies Phase 3,Phase 2,Phase 1,Not Applicable
45 Antibodies, Monoclonal Phase 3,Phase 2,Phase 1,Not Applicable
46 Histamine Antagonists Phase 3
47 Psychotropic Drugs Phase 3
48 Central Nervous System Depressants Phase 3
49 Antidepressive Agents, Tricyclic Phase 3
50 Antidepressive Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 141)
# Name Status NCT ID Phase Drugs
1 PET/CT Scan-Guided Watchful Waiting or Neck Dissection of Locally Advanced Lymph Node Metastases in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Primary Head And Neck Cancer Unknown status NCT00720070 Phase 3
2 Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy Completed NCT01156142 Phase 3 doxepin hydrochloride
3 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
4 Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Head and Neck Cancer Completed NCT00002476 Phase 3 fluorouracil;leucovorin calcium;methotrexate;vincristine sulfate
5 Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer Completed NCT00090337 Phase 3
6 Study of Nutrition Regimens in Treating Patients With Cancer of the Upper Aerodigestive Tract Completed NCT00765440 Phase 3
7 Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer Completed NCT00002533 Phase 2, Phase 3 fluconazole
8 Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer Completed NCT00017511 Phase 3 cevimeline hydrochloride
9 Radiation Therapy and Cisplatin or Panitumumab in Treating Patients With Locally Advanced Stage III or Stage IV Head and Neck Cancer Completed NCT00820248 Phase 3 cisplatin
10 Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer Completed NCT00006799 Phase 3 megestrol acetate
11 Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Active, not recruiting NCT00588770 Phase 3 Carboplatin;Cisplatin;Docetaxel;Fluorouracil
12 Radiation Therapy With Cisplatin, Docetaxel, or Cetuximab After Surgery in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Active, not recruiting NCT01810913 Phase 2, Phase 3 cisplatin;docetaxel
13 Radiation Therapy With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer Active, not recruiting NCT00956007 Phase 3
14 CD2 Lozenges in Preventing Acute Oral Mucositis in Patients With Head and Neck Cancer Receiving Radiotherapy and Chemotherapy Withdrawn NCT01545687 Phase 3
15 Docetaxel and St. John's Wort in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery Withdrawn NCT00041171 Phase 3 Hypericum perforatum;docetaxel
16 PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Unknown status NCT01816984 Phase 1, Phase 2 PI3K inhibitor BKM120
17 Docetaxel and S-1 Followed By Radiation Therapy and Low-Dose Cisplatin in Treating Patients With Stage III or Stage IV Head and Neck Cancer Unknown status NCT00625937 Phase 2 cisplatin;docetaxel;tegafur-gimeracil-oteracil potassium
18 Cisplatin-Epinephrine Injectable Gel Plus Paclitaxel and Carboplatin in Treating Patients With Recurrent Head and Neck Cancer Unknown status NCT00022217 Phase 2 carboplatin;cisplatin-e therapeutic implant;paclitaxel
19 Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer Unknown status NCT00721513 Phase 2 cisplatin;docetaxel;fluorouracil
20 External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases Unknown status NCT00637637 Phase 2 indinavir sulfate;ritonavir
21 Efficacy of VIUSID® Plus GLIZIGEN® in Patients With Papilloma Virus Esophageal Completed NCT03584308 Phase 2
22 Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery Completed NCT02007200 Phase 2 Soy Isoflavones
23 Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy Completed NCT01256385 Phase 2 Temsirolimus
24 Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy Completed NCT02123511 Phase 2 acetylcysteine
25 Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer Completed NCT00458978 Phase 2 Cediranib Maleate
26 Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab Completed NCT00939627 Phase 2 sorafenib tosylate
27 Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer Completed NCT02048020 Phase 2 paclitaxel;carboplatin
28 Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer. Completed NCT01469429 Phase 1, Phase 2 chemoprevention;chemoprevention
29 Saracatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Completed NCT00513435 Phase 2 saracatinib
30 Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Completed NCT00507767 Phase 2 dasatinib
31 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer Completed NCT00492089 Phase 2 bevacizumab;placebo
32 Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer Completed NCT00114283 Phase 2 lapatinib ditosylate
33 S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Completed NCT00096512 Phase 2 sorafenib tosylate
34 Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancer Completed NCT00101348 Phase 1, Phase 2 erlotinib hydrochloride
35 Bortezomib With or Without Irinotecan in Treating Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Completed NCT00103259 Phase 2 bortezomib;irinotecan hydrochloride
36 Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer Completed NCT01316757 Phase 2 paclitaxel;carboplatin;erlotinib hydrochloride
37 Ixabepilone in Treating Patients With Metastatic or Recurrent Squamous Cell Cancer of the Head and Neck Completed NCT00033618 Phase 2 ixabepilone
38 Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck Completed NCT01044433 Phase 2 lapatinib ditosylate;capecitabine
39 SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Completed NCT00095628 Phase 2 ispinesib
40 Chemotherapy in Treating Patients With Solid Tumors Completed NCT00003103 Phase 1, Phase 2 docetaxel
41 High-dose ICE With Amifostine Completed NCT00003657 Phase 2 Amifostine;Carboplatin;Etoposide;Ifosfamide
42 Oxaliplatin and Capecitabine in Treating Patients With Relapsed or Metastatic Head and Neck Cancer Completed NCT00448552 Phase 2 capecitabine;oxaliplatin
43 Cetuximab and Stereotactic Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery Completed NCT00738868 Phase 2
44 Docetaxel in Treating Patients With Solid Tumors Completed NCT00003565 Phase 2 docetaxel
45 Irinotecan and Cisplatin in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Completed NCT00639769 Phase 2 cisplatin;irinotecan hydrochloride
46 Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and Neck Completed NCT00720304 Phase 2 docetaxel;erlotinib hydrochloride
47 Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Mouth Cancer Completed NCT00004901 Phase 1, Phase 2 ethynyluracil;fluorouracil;hydroxyurea
48 Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor Completed NCT00021047 Phase 1, Phase 2 capecitabine;carboplatin;epirubicin hydrochloride
49 Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors Completed NCT00019331 Phase 2 DetoxPC
50 Gemcitabine and Doxorubicin in Treating Patients With Recurrent or Progressive Head and Neck Cancer Completed NCT00509665 Phase 2 doxorubicin hydrochloride;gemcitabine hydrochloride

Search NIH Clinical Center for Verrucous Carcinoma

Cochrane evidence based reviews: carcinoma, verrucous

Genetic Tests for Verrucous Carcinoma

Anatomical Context for Verrucous Carcinoma

MalaCards organs/tissues related to Verrucous Carcinoma:

42
Skin, Cervix, Brain, Lymph Node, T Cells, Tongue, Colon

Publications for Verrucous Carcinoma

Articles related to Verrucous Carcinoma:

(show top 50) (show all 669)
# Title Authors Year
1
Verrucous carcinoma: An unexpected finding arising from a burn scar. ( 30809566 )
2019
2
Verrucous carcinoma arising in a long standing Buschke-Löwenstein tumor. ( 30997098 )
2019
3
Downregulation of Notch4 - a prognostic marker in distinguishing oral verrucous carcinoma from oral squamous cell carcinoma. ( 29162408 )
2019
4
Verrucous Carcinoma Arising in Association With Giant Condyloma. ( 30185090 )
2019
5
Human papillomavirus infection is not involved in esophageal verrucous carcinoma. ( 30423307 )
2019
6
Lichenoid Characteristics in Premalignant Verrucous Lesions and Verrucous Carcinoma of the Oral Cavity. ( 30671763 )
2019
7
A first case of primary gastric verrucous carcinoma with isolated squamous epithelium in the stomach. ( 30761414 )
2019
8
Verrucous carcinoma on the foot arising in a chronic neuropathic ulcer of leprosy. ( 30841011 )
2019
9
Organ-Sparing Surgery for a Giant Verrucous Carcinoma of the Penile Shaft: A Case Report and Review of the Literature. ( 30918740 )
2019
10
Is primary radiotherapy an acceptable treatment modality for verrucous carcinoma of the larynx? ( 30950508 )
2019
11
Verrucous Carcinoma of the Vulva: A Case Report and Literature Review. ( 31002657 )
2019
12
First case report of malignant peritoneal mesothelioma and oral verrucous carcinoma in a patient with a germline PTEN mutation: a combination of extremely rare diseases with probable further implications. ( 30111295 )
2018
13
BCL-X expression in oral cancer: Comparison between oral squamous cell carcinoma and verrucous carcinoma. ( 29652014 )
2018
14
Syringocystadenoma Papilliferum in Coexistence With Verrucous Carcinoma on the Face. ( 29112527 )
2018
15
Verrucous carcinoma of the oesophagus. ( 28116819 )
2018
16
A population-based analysis of verrucous carcinoma of the oral cavity. ( 28850720 )
2018
17
Epidemiology and survival outcomes of sinonasal verrucous carcinoma in the United States. ( 28865078 )
2018
18
Verrucous carcinoma of the esophagus: A rare entity with a difficult diagnosis. ( 29452967 )
2018
19
Two Cases of Verrucous Carcinoma: Revisiting the Definition. ( 29540646 )
2018
20
A Case of Oral Florid Papillomatosis (Verrucous Carcinoma) With Lack of Evidence for Human Papillomavirus Involvement. ( 29697424 )
2018
21
Verrucous carcinoma of the esophagus-remains a diagnostic enigma. ( 29748561 )
2018
22
Mistaken Diabetic Ulcers: A Case of Bilateral Foot Verrucous Carcinoma. ( 29796321 )
2018
23
Corrigendum to "Mistaken Diabetic Ulcers: A Case of Bilateral Foot Verrucous Carcinoma". ( 29849220 )
2018
24
Recalcitrant lip verrucous carcinoma successfully treated with acitretin after carbon dioxide laser ablation. ( 29998178 )
2018
25
Treatment of verrucous carcinoma in penis with topical aminolevulinic acid photodynamic therapy: An effective and safe treatment method. ( 30205190 )
2018
26
Verrucous carcinoma arising from a previous cystic lesion: a case report. ( 30397593 )
2018
27
Anogenital Verrucous Carcinoma-A case report. ( 30508696 )
2018
28
Cutaneous Verrucous Carcinoma Superimposed on Chronically Inflamed Ileostomy Site Skin: A Case Report. ( 30697301 )
2018
29
A Rare Case of Esophageal Verrucous Squamous Cell Carcinoma in a Patient With Achalasia. ( 28063972 )
2017
30
A clitoral verrucous carcinoma in an area of lichen planus has aggressive features. ( 28061900 )
2017
31
Association of Macrophages With Angiogenesis in Oral Epithelial Dysplasia, Oral Verrucous Carcinoma, and Oral Squamous Cell Carcinoma: An Immunohistochemical Study. ( 26657870 )
2017
32
Human Papilloma Virus-Associated Lips Verrucous Carcinoma in HIV-Infected Male. ( 28565927 )
2017
33
Antioxidant enzymes in oral verrucous carcinoma. ( 27245640 )
2017
34
Laryngeal Verrucous Carcinoma. ( 27484231 )
2017
35
Diagnostic Biomarkers in Oral Verrucous Carcinoma: A Systematic Review. ( 27924463 )
2017
36
Anal verrucous carcinoma is not related to infection with human papillomaviruses and should be distinguished from giant condyloma (Buschke-Löwenstein tumour). ( 28012208 )
2017
37
Adjuvant radiotherapy is not supported in patients with verrucous carcinoma of the oral cavity. ( 28150306 )
2017
38
Verrucous carcinoma of the buccal mucosa with extension to the cheek. ( 28319631 )
2017
39
Rare "Inverted" Verrucous Carcinoma (Carcinoma Cuniculatum) of the Sacrogluteal Region: Case Report and Literature Review. ( 28381141 )
2017
40
Local Excision for the Treatment of Penile Verrucous Carcinoma. ( 28417078 )
2017
41
Good Prognosis Went Badly: Fulminant Evolution of a 29-Year-Old Patient with Verrucous Carcinoma of the Cervix. ( 28498727 )
2017
42
A Giant Cutaneous Horn Projecting from Verrucous Carcinoma of Buccal Mucosa: A Rare Case Report. ( 28511519 )
2017
43
Verrucous carcinoma of the vulva: diagnosis and treatment. ( 28538888 )
2017
44
Comorbidity between HTLV-1-associated adult T-cell lymphoma/leukemia and verrucous carcinoma: a case report. ( 28559645 )
2017
45
Research on miRNA-195 and target gene CDK6 in oral verrucous carcinoma. ( 28621315 )
2017
46
Verrucous carcinoma of foot at an unusual site: Lessons to be learnt. ( 28702408 )
2017
47
Malignant Transformation of a Site of Prior Diabetic Foot Ulceration to Verrucous Carcinoma: A Case Report. ( 29324428 )
2017
48
Oral Verrucous Carcinoma: Ten Year Experience from a Tertiary Care Hospital in India. ( 29333011 )
2017
49
Expression of Cell Cycle-associated Proteins p53, pRb, p16, p27, and Correlation With Survival: A Comparative Study on Oral Squamous Cell Carcinoma and Verrucous Carcinoma. ( 26447892 )
2016
50
Pyoderma Vegetans Misdiagnosed as Verrucous Carcinoma. ( 26825160 )
2016

Variations for Verrucous Carcinoma

Expression for Verrucous Carcinoma

Search GEO for disease gene expression data for Verrucous Carcinoma.

Pathways for Verrucous Carcinoma

Pathways related to Verrucous Carcinoma according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.66 CCND1 CDKN2A MDM2 MSN NOTCH4 TP53
2
Show member pathways
12.82 CCND1 MDM2 NOTCH4 TP53
3
Show member pathways
12.71 CCND1 CDKN2A MDM2 TP53
4
Show member pathways
12.61 CCND1 CDKN2A NOTCH4 TP53
5
Show member pathways
12.5 CCND1 CDKN2A MDM2 NOTCH4 TP53
6
Show member pathways
12.47 CCND1 MDM2 SLC2A1 TP53
7 12.46 CCND1 CDKN2A MDM2 NOTCH4 SLC2A1 TP53
8
Show member pathways
12.45 CCND1 CDKN2A MDM2 TP53
9 12.39 CCND1 CDKN2A MDM2 TP53
10
Show member pathways
12.25 CCND1 CDKN2A MDM2 TP53
11
Show member pathways
12.24 CCND1 MDM2 TP53
12 12.24 CCND1 CDKN2A MDM2 TP53
13 12.23 CCND1 CDKN2A SLC2A1 TP53
14
Show member pathways
12.21 CCND1 CDKN2A TP53
15 12.2 CCND1 CDKN2A MDM2 NOTCH4 TP53
16 12.15 CCND1 MDM2 MSN TP53
17 12.14 CCND1 CDKN2A MDM2 TP53
18
Show member pathways
12.11 CCND1 MDM2 TP53
19 12.01 CCND1 MDM2 TP53
20 12 CCND1 MDM2 TP53
21 12 CCND1 CDKN2A MDM2 TP53
22 11.92 CDKN2A MDM2 TP53
23
Show member pathways
11.91 CCND1 NOTCH4 TP53
24 11.83 CDKN2A MDM2 TP53
25 11.82 CCND1 CDKN2A MDM2 TP53
26 11.74 CCND1 MDM2 TP53
27 11.71 CCND1 CDKN2A MDM2 TP53
28 11.64 CDKN2A MDM2 TP53
29
Show member pathways
11.64 CDKN2A MDM2 TP53
30 11.56 CDKN2A MDM2 TP53
31 11.48 CCND1 MDM2 TP53
32 11.44 CCND1 CDKN2A TP53
33 11.42 CCND1 MDM2 NOTCH4 SLC2A1 TP53
34 11.34 CCND1 MDM2 TP53
35 11.25 SLC2A1 TP53
36 11.19 CDKN2A MDM2 SLC2A1 TP53
37 11.18 CCND1 TP53
38 11.16 MDM2 TP53
39 11.16 CDKN2A MDM2 TP53
40 10.95 CDKN2A MDM2 TP53
41
Show member pathways
10.92 CDKN2A MDM2 TP53
42 10.88 CCND1 CDKN2A MDM2 TP53 TYMP

GO Terms for Verrucous Carcinoma

Cellular components related to Verrucous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.28 CCND1 CDKN2A KRT10 MDM2 MSN NOTCH4

Biological processes related to Verrucous Carcinoma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.71 CDKN2A MDM2 MSN TP53
2 protein sumoylation GO:0016925 9.54 CDKN2A MDM2
3 protein-containing complex assembly GO:0065003 9.54 MDM2 SLC2A1 TP53
4 response to antibiotic GO:0046677 9.52 MDM2 TP53
5 response to steroid hormone GO:0048545 9.51 CCND1 MDM2
6 cellular response to gamma radiation GO:0071480 9.49 MDM2 TP53
7 negative regulation of cell cycle arrest GO:0071157 9.48 CCND1 MDM2
8 positive regulation of protein export from nucleus GO:0046827 9.46 MDM2 TP53
9 response to iron ion GO:0010039 9.43 CCND1 MDM2
10 replicative senescence GO:0090399 9.32 CDKN2A TP53
11 response to magnesium ion GO:0032026 9.26 CCND1 MDM2
12 amyloid fibril formation GO:1990000 9.16 CDKN2A MDM2
13 mitotic G1 DNA damage checkpoint GO:0031571 8.96 CCND1 TP53
14 cellular response to actinomycin D GO:0072717 8.62 MDM2 TP53

Molecular functions related to Verrucous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 9.46 CCND1 CDKN2A MSN TP53
2 SUMO transferase activity GO:0019789 9.26 CDKN2A MDM2
3 enzyme binding GO:0019899 9.26 CCND1 MDM2 MSN TP53
4 disordered domain specific binding GO:0097718 8.8 CDKN2A MDM2 TP53

Sources for Verrucous Carcinoma

3 CDC
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10 dbSNP
11 DGIdb
17 EFO
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31 HGMD
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70 SNOMED-CT via HPO
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