MCID: VRT001
MIFTS: 29

Vertebral Artery Occlusion

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Vertebral Artery Occlusion

MalaCards integrated aliases for Vertebral Artery Occlusion:

Name: Vertebral Artery Occlusion 12 15 70
Occlusion and Stenosis of Vertebral Artery 12 32

Classifications:



External Ids:

Disease Ontology 12 DOID:11299
ICD9CM 34 433.2
ICD10 32 I65.0
UMLS 70 C0155724 C0265104

Summaries for Vertebral Artery Occlusion

MalaCards based summary : Vertebral Artery Occlusion, also known as occlusion and stenosis of vertebral artery, is related to basilar artery occlusion and brain stem infarction. An important gene associated with Vertebral Artery Occlusion is CPNE9 (Copine Family Member 9), and among its related pathways/superpathways are Cell adhesion_ECM remodeling and Cell adhesion_Plasmin signaling. Affiliated tissues include spinal cord, brain and heart.

Related Diseases for Vertebral Artery Occlusion

Diseases related to Vertebral Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Related Disease Score Top Affiliating Genes
1 basilar artery occlusion 30.8 PLG PLAT
2 brain stem infarction 30.6 PLG PLAT
3 intracranial embolism 30.4 PLG PLAT
4 posterior cerebral artery infarction 30.2 PLG PLAT
5 carotid artery disease 29.7 PLG PLAT
6 vertebrobasilar insufficiency 10.6
7 aneurysm 10.5
8 bow hunter's stroke 10.5
9 mucopolysaccharidosis, type ii 10.3
10 pica disease 10.3
11 pathologic nystagmus 10.3
12 lateral medullary syndrome 10.3
13 syncope 10.3
14 cerebellar ataxia type 41 10.2 HPCAL4 CPNE9
15 cerebellar ataxia type 42 10.2 HPCAL4 CPNE9
16 basal ganglia cerebrovascular disease 10.2 PLG PLAT
17 ligneous conjunctivitis 10.2 PLG PLAT
18 cerebral falx meningioma 10.2 PLG PLAT
19 basilar artery insufficiency 10.2 PLG PLAT
20 acute pulmonary heart disease 10.2 PLG PLAT
21 acute cor pulmonale 10.2 PLG PLAT
22 inferior myocardial infarction 10.2 PLG PLAT
23 plasminogen deficiency, type i 10.2 PLG PLAT
24 conversion disorder 10.2 PLG PLAT
25 head injury 10.2
26 headache 10.2
27 anterior cerebral artery infarction 10.2 PLG PLAT
28 perforated corneal ulcer 10.2 PLG PLAT
29 hereditary angioedema with normal c1inh 10.2 PLG PLAT
30 central retinal artery occlusion 10.2 PLG PLAT
31 middle cerebral artery infarction 10.2 PLG PLAT
32 occlusion precerebral artery 10.2 PLG PLAT
33 carotid artery thrombosis 10.1 PLG PLAT
34 cardiac tamponade 10.1 PLG PLAT
35 post-thrombotic syndrome 10.1 PLG PLAT
36 intracranial thrombosis 10.1 PLG PLAT
37 carotid artery occlusion 10.1 PLG PLAT
38 stroke, ischemic 10.1
39 hydrocephalus 10.1
40 subclavian steal syndrome 10.1
41 vertebral artery insufficiency 10.1
42 exostosis 10.1
43 transient cerebral ischemia 10.1
44 cranial nerve palsy 10.1
45 osteochondroma 10.1
46 spinal cord injury 10.1
47 thrombophlebitis 10.1 PLG PLAT
48 coronary thrombosis 10.1 PLG PLAT
49 pulmonary artery disease 10.1 PLG PLAT
50 intermediate coronary syndrome 10.0 PLG PLAT

Graphical network of the top 20 diseases related to Vertebral Artery Occlusion:



Diseases related to Vertebral Artery Occlusion

Symptoms & Phenotypes for Vertebral Artery Occlusion

Drugs & Therapeutics for Vertebral Artery Occlusion

Search Clinical Trials , NIH Clinical Center for Vertebral Artery Occlusion

Genetic Tests for Vertebral Artery Occlusion

Anatomical Context for Vertebral Artery Occlusion

MalaCards organs/tissues related to Vertebral Artery Occlusion:

40
Spinal Cord, Brain, Heart

Publications for Vertebral Artery Occlusion

Articles related to Vertebral Artery Occlusion:

(show top 50) (show all 370)
# Title Authors PMID Year
1
Letter to the Editor concerning "Rotational vertebral artery occlusion ('bow hunter syndrome')" by Schulz R, Donoso R, Weissman K (Eur Spine J. 2021 Jan 2. doi:10.1007/s00586-020-06, 680-5). 61
33661395 2021
2
Answer to the Letter to the Editor of P. Missori et al. concerning "Rotational vertebral artery occlusion ('bow hunter syndrome')" by Schulz R, Donoso R, Weissman K (Eur Spine J; 2021 Jan 2. https://doi.org/10.1007/s00586-020-06680-5). 61
33710421 2021
3
Posterior Circulation Endovascular Thrombectomy for Large-Vessel Occlusion: Predictors of Favorable Clinical Outcome and Analysis of First-Pass Effect. 61
33664106 2021
4
A novel angiographic classification for the endovascular recanalization of symptomatic nonacute extracranial vertebral artery occlusion. 61
33722973 2021
5
Ruptured Spinal Aneurysms: Diagnosis and Management Paradigms. 61
33223127 2021
6
Modified Sternocleidomastoid Sparing Approach for Vertebral Artery (V1) to Common Carotid Artery Transposition: 2-Dimensional Operative Video. 61
33611544 2021
7
Multiple Fractures of Cervical Vertebrae Combined with Arcuate Foramen and Vertebral Artery Occlusion: A Case Report and Literature Review. 61
33274600 2021
8
Rotational vertebral artery occlusion ("bow hunter syndrome"). 61
33389200 2021
9
Pyogenic Atlantoaxial Rotational Dislocation Representing Adult Torticollis with Vertebral Artery Occlusion: A Case Report and Review. 61
32889186 2020
10
[A Case of Positional Vertebral Artery Occlusion due to Physiological Cervical Extension with Occipital Condylar Spur]. 61
33353881 2020
11
Cerebellar infarction requiring surgical decompression in patient with COVID 19 pathological analysis and brief review. 61
32835021 2020
12
Dynamic CT angiography of the head and neck in the diagnosis of Bow Hunter's Syndrome: A case report. 61
32983299 2020
13
Natural Prognosis of Pediatric Rotational Vertebral Artery Occlusion: A Reversible Case Report. 61
33342907 2020
14
Endovascular Recanalization for Nonacute Intracranial Vertebral Artery Occlusion According to a New Classification. 61
32838672 2020
15
A Case of Bilateral Hearing Loss. 61
33217290 2020
16
Bow Hunter's Syndrome in Children: A Review of the Literature and Presentation of a New Case in a 12-Year-Old Girl. 61
32507079 2020
17
Endovascular treatment combined with vertebral artery endarterectomy for patients with acute tandem vertebrobasilar artery occlusion. 61
33070898 2020
18
Focal Cerebellar Hyperperfusion After Bypass Surgery for Vertebrobasilar Ischemia: Effect of Cerebrovascular Reactivity as a Potential Predictor of Hyperperfusion. 61
32428717 2020
19
C1-C2 posterior screw fixation in atlantoaxial fractures revisited: technical update based on 127 cases. 61
31823086 2020
20
Endovascular Revascularization of Nonacute Symptomatic Proximal Extracranial Vertebral Artery Occlusion. 61
31629152 2020
21
Bow Hunter's syndrome combined with ipsilateral vertebral artery dissection/pseudoaneurysm: case study and literature review. 61
32009470 2020
22
Pediatric Patient With a Giant Vertebrobasilar Dissecting Aneurysm Successfully Treated With Three Pipeline Embolization Devices. 61
32719653 2020
23
Symptomatic Atherosclerotic Non-acute Intracranial Vertebral Artery Total Occlusion: Clinical Features, Imaging Characteristics, Endovascular Recanalization, and Follow-up Outcomes. 61
33312156 2020
24
Safety and Blood-Flow Outcomes for Hybrid Recanalization in Symptomatic Refractory Long-Segmental Vertebral Artery Occlusion-Results of a Pilot Study. 61
32477250 2020
25
Cervical Spine Ischemic Stroke Complicated by Spastic Quadriparesis and Ogilvie Syndrome: A Case Report and Literature Review. 61
32733721 2020
26
Atlanto-occipital ligament calcification: a novel imaging finding in pediatric rotational vertebral artery occlusion. 61
31511914 2020
27
Positional transient loss of consciousness and hemispheric deficits in the setting of severe four-vessel extracranial cerebrovascular disease. 61
31737804 2019
28
[Reduction of the atlantoaxial dislocation associated with basilar invagination through single-stage posterior approach: using Xuanwu occipital-cervical reduction surgical suite]. 61
31510735 2019
29
The Vertebral Artery Convergence to the Cervical Spine in Elders. 61
32337923 2019
30
Bilateral vertebral artery occlusion without stroke secondary to giant cell arteritis. 61
31575840 2019
31
Prevention of Thromboembolic Infarction After Surgery for Traumatic Cervical Fracture with Vertebral Artery Occlusion by Preoperative Endovascular Coil Embolization. 61
31207373 2019
32
Letter to the Editor. Endovascular revascularization for symptomatic extracranial vertebral artery occlusion. 61
31473674 2019
33
C2-3 Fracture Dislocation and Bilateral Vertebral Artery Occlusion Without Neurological Injury: A Case Report. 61
31687311 2019
34
Traumatic posterior atlantoaxial dislocation with associated C1 Jefferson fracture and bilateral vertebral artery occlusion without odontoid process fracture or neurological deficit. 61
29961910 2019
35
Steroid refractory giant cell arteritis with bilateral vertebral artery occlusion and middle cerebellar peduncle infarction. 61
31188339 2019
36
Successful endovascular coil embolisation of a ruptured V1-segment vertebral artery dissecting aneurysm making a fistula with the adjacent vein. 61
31171534 2019
37
Resolution of Hypoxic Tissue in Cerebellar Hemispheres After Arterial Bypass Surgery in a Patient With Symptomatic Bilateral Vertebral Artery Occlusion: A 18F-FRP170 PET Study. 61
30688740 2019
38
Rotational vertebral artery occlusion secondary to completely extraosseous vertebral artery. 61
30619984 2019
39
Lateral Medullary Syndrome Due to Left Vertebral Artery Occlusion in a Boy Postflexion Neck Injury. 61
31763345 2019
40
Rotational vertebral artery occlusion in a patient with basilar invagination. 61
30652932 2019
41
Bilateral vertebral artery occlusion after cervical spine fracture dislocation. 61
30684719 2019
42
Bithalamic Infarction (Artery of Percheron Occlusion) after Anterior Cervical Discectomy and Fusion. 61
31011457 2019
43
Compression Syndromes of the Vertebral Artery at the Craniocervical Junction. 61
30610316 2019
44
Intravenous Thrombolysis in Posterior Circulation Stroke. 61
31080436 2019
45
Bidirectional Transradial and Transfemoral Approach for Stent-Assisted Coil Embolization of Right Subclavian Artery Saccular Aneurysm. 61
29716478 2018
46
Fine margin between crossed sensory and contralateral sensory loss: A case report. 61
29937417 2018
47
C2-C3 Anterior Cervical Arthrodesis in the Treatment of Bow Hunter's Syndrome: Case Report and Review of the Literature. 61
30053560 2018
48
Coil Embolization through Collateral Pathway for Ruptured Vertebral Artery Dissecting Aneurysm with Bilateral Vertebral Artery Occlusion. 61
29914759 2018
49
Resolution of traumatic bilateral vertebral artery injury. 61
29497851 2018
50
Favorable Long-Term Outcomes for Positional Vertebral Artery Occlusion with Treatment Strategy Prioritizing Spinal Fusion Surgery. 61
29572170 2018

Variations for Vertebral Artery Occlusion

Expression for Vertebral Artery Occlusion

Search GEO for disease gene expression data for Vertebral Artery Occlusion.

Pathways for Vertebral Artery Occlusion

Pathways related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.11 PLG PLAT
2 10.95 PLG PLAT
3 10.84 PLG PLAT
4 10.32 PLG PLAT
5 9.74 PLG PLAT

GO Terms for Vertebral Artery Occlusion

Cellular components related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 synapse GO:0045202 9.46 NCDN LY6H CPNE6 CLSTN3
2 glutamatergic synapse GO:0098978 9.43 PLAT CLSTN3 CACNG3
3 integral component of postsynaptic density membrane GO:0099061 8.96 CLSTN3 CACNG3
4 dendrite GO:0030425 8.92 NCDN CPNE6 CLSTN3 CACNG3

Biological processes related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of dendrite extension GO:1903861 8.96 CPNE9 CPNE6
2 fibrinolysis GO:0042730 8.62 PLG PLAT

Molecular functions related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium-dependent phospholipid binding GO:0005544 8.62 CPNE9 CPNE6

Sources for Vertebral Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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