MCID: VRT001
MIFTS: 31

Vertebral Artery Occlusion

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Vertebral Artery Occlusion

MalaCards integrated aliases for Vertebral Artery Occlusion:

Name: Vertebral Artery Occlusion 12 15 73
Occlusion and Stenosis of Vertebral Artery 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11299
ICD10 33 I65.0
ICD9CM 35 433.2

Summaries for Vertebral Artery Occlusion

MalaCards based summary : Vertebral Artery Occlusion, also known as occlusion and stenosis of vertebral artery, is related to basilar artery occlusion and conjugate gaze palsy. An important gene associated with Vertebral Artery Occlusion is AARS (Alanyl-TRNA Synthetase), and among its related pathways/superpathways are IL-1 Family Signaling Pathways and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Affiliated tissues include brain and bone, and related phenotypes are growth/size/body region and integument

Related Diseases for Vertebral Artery Occlusion

Diseases related to Vertebral Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Related Disease Score Top Affiliating Genes
1 basilar artery occlusion 29.3 FOSB PLG SLC25A16
2 conjugate gaze palsy 10.6 F3 PLG
3 cerebral falx meningioma 10.6 F3 PLG
4 intestinal impaction 10.6 F3 PLG
5 leech infestation 10.5 F3 PLG
6 giant hemangioma 10.5 F3 PLG
7 blue toe syndrome 10.5 F3 PLG
8 intracranial embolism 10.5 F3 PLG
9 femoral neuropathy 10.5 F3 PLG
10 nodular ganglioneuroblastoma 10.5 BDNF NTRK2
11 cervicitis 10.5
12 anterior cranial fossa meningioma 10.4 F3 PLG
13 dysbaric osteonecrosis 10.4 F3 PLG
14 korean hemorrhagic fever 10.4 F3 PLG
15 cerebral arterial disease 10.4 MRAS SLC25A16
16 lemierre's syndrome 10.3 F3 PLG SLC25A16
17 aneurysm 10.3
18 hemometra 10.3 F3 SLC25A16
19 undetermined early-onset epileptic encephalopathy 10.2 AARS NTRK2
20 carotid artery thrombosis 10.2 CSF2 F3
21 central nervous system disease 10.2 BDNF NOS2 RBFOX3
22 hepatic vascular disease 10.1 F3 PLG SST
23 vein disease 10.1 F3 PLG SST
24 status epilepticus 10.1 BDNF NTRK2 SST
25 vertebrobasilar insufficiency 10.0
26 rheumatoid arthritis 9.9
27 arthritis 9.9
28 ischemia 9.9
29 lateral medullary syndrome 9.9
30 brain stem infarction 9.9
31 bow hunter's stroke 9.9
32 osteochondroma 9.9
33 headache 9.9
34 intermediate coronary syndrome 9.8 F3 PLG
35 nervous system disease 9.7 BDNF CSF2 NOS2 RBFOX3
36 nevus, epidermal 9.7
37 nasopharyngeal carcinoma 9.7
38 hydrocephalus 9.7
39 hemidystonia 9.7
40 thrombosis 9.7
41 nasopharyngitis 9.7
42 acute cervicitis 9.7
43 intracranial aneurysm 9.7
44 vestibular neuronitis 9.7
45 locked-in syndrome 9.7
46 spondylosis 9.7
47 cerebritis 9.7
48 neuronitis 9.7
49 carotid artery dissection 9.7
50 neurofibroma 9.7

Graphical network of the top 20 diseases related to Vertebral Artery Occlusion:



Diseases related to Vertebral Artery Occlusion

Symptoms & Phenotypes for Vertebral Artery Occlusion

MGI Mouse Phenotypes related to Vertebral Artery Occlusion:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.96 NOS2 NTRK2 PLG AARS SOCS2 SST
2 integument MP:0010771 9.7 NOS2 PLG AARS SOCS2 BDNF CSF2
3 nervous system MP:0003631 9.61 FOSB NOS2 NTRK2 PLG AARS SST
4 respiratory system MP:0005388 9.17 NOS2 NTRK2 PLG SOCS2 BDNF CSF2

Drugs & Therapeutics for Vertebral Artery Occlusion

Search Clinical Trials , NIH Clinical Center for Vertebral Artery Occlusion

Genetic Tests for Vertebral Artery Occlusion

Anatomical Context for Vertebral Artery Occlusion

MalaCards organs/tissues related to Vertebral Artery Occlusion:

41
Brain, Bone

Publications for Vertebral Artery Occlusion

Articles related to Vertebral Artery Occlusion:

(show top 50) (show all 149)
# Title Authors Year
1
Traumatic posterior atlantoaxial dislocation with associated C1 Jefferson fracture and bilateral vertebral artery occlusion without odontoid process fracture or neurological deficit. ( 29961910 )
2018
2
Favorable Long-Term Outcomes for Positional Vertebral Artery Occlusion with Treatment Strategy Prioritizing Spinal Fusion Surgery. ( 29572170 )
2018
3
Vertebral Artery Occlusion Causing Facial Colliculus and Opalski Stroke Syndromes Simultaneously. ( 29722745 )
2018
4
Two-stage corrective surgery for severe rigid cervical kyphotic deformity with unilateral vertebral artery occlusion after old blunt trauma: a case report. ( 29531796 )
2018
5
Awareness of traumatic occult lateral mass fracture of the cervical spine triggered by the presence of unilateral vertebral artery occlusion: a case report. ( 29560277 )
2018
6
Successful retrograde recanalization of acute right dominant vertebral artery occlusion through the left posterior communicating artery in a patient with acute vertebrobasilar ischemic stroke. ( 29682138 )
2018
7
Coil Embolization through Collateral Pathway for Ruptured Vertebral Artery Dissecting Aneurysm with Bilateral Vertebral Artery Occlusion. ( 29914759 )
2018
8
Vertebral artery occlusion after anterior cervical discectomy with fusion. ( 29736229 )
2017
9
Evaluation of a Traumatic Vertebral Artery Occlusion. ( 28254602 )
2017
10
Rapid Progression of Vertebral Artery Occlusion After Radiotherapy for Nasopharyngeal Carcinoma. ( 29250760 )
2017
11
Cryptic Recanalization of Chronic Vertebral Artery Occlusion by Head Rotation. ( 28117210 )
2017
12
Combined Use of Intraoperative Indocyanine Green and Dynamic Angiography in Rotational Vertebral Artery Occlusion. ( 29114306 )
2017
13
Congenital Spinal Malformation and Stroke: Aneurysmal Dilatations and Bilateral Rotational Vertebral Artery Occlusion. ( 26679068 )
2016
14
Combined use of intraoperative indocyanine green and dynamic angiography in rotational vertebral artery occlusion. ( 27041076 )
2016
15
Delayed bilateral vertebral artery occlusion after cervical spine injury: a case report. ( 28053772 )
2016
16
Bilateral vertebral artery occlusion without headache in giant cell arteritis. ( 27508209 )
2016
17
Temporary vertebral artery occlusion after C3 fracture dislocation injury and spontaneous resolution following reduction and instrumented fusion: case report and literature review. ( 27798854 )
2016
18
Duplex Ultrasonography-Detected Positional Vertebral Artery Occlusion in Upper Cervical Rheumatoid Arthritis. ( 26583470 )
2016
19
Therapeutic internal carotid or vertebral artery occlusion using the WEB device. ( 26861025 )
2016
20
Bilateral sub-axial rotational vertebral artery occlusion in a setting of a prior cervical construct. ( 27609452 )
2016
21
Vertebral artery occlusion and recanalization after cervical facet dislocation. ( 27535628 )
2016
22
A Novel Canine Model of Acute Vertebral Artery Occlusion. ( 26545253 )
2015
23
Rotational vertebral artery occlusion syndrome: Misnomers and classification. ( 25660966 )
2015
24
Wake-up stroke in a young woman with rotational vertebral artery occlusion due to far-lateral cervical disc herniation. ( 25932602 )
2015
25
Bilateral Medial Medullary Infarction with Nondominant Vertebral Artery Occlusion. ( 26175270 )
2015
26
Corrective spinal surgery may be protective against stroke in patients with blunt traumatic vertebral artery occlusion. ( 26186525 )
2015
27
Ruptured Anterior Spinal Artery Aneurysm Associated with Bilateral Vertebral Artery Occlusion Treated by Surgical Clipping. ( 26079782 )
2015
28
Fusion Surgery for Recurrent Cerebellar Infarctions due to Bilateral Atlanto-axial Rotational Vertebral Artery Occlusion. ( 24732857 )
2014
29
Distal embolic brain infarction due to recanalization of asymptomatic vertebral artery occlusion resulting from cervical spine injury: a case report. ( 25435840 )
2014
30
Preoperative visualization of the marginal tentorial artery as an unusual collateral pathway in a patient with symptomatic bilateral vertebral artery occlusion undergoing arterial bypass surgery: A 7.0-T magnetic resonance imaging study. ( 25422785 )
2014
31
Fusion surgery for recurrent cerebellar infarctions due to bilateral atlantoaxial rotational vertebral artery occlusion. ( 24918470 )
2014
32
Spontaneous atraumatic vertebral artery occlusion due to physiological cervical extension: case report. ( 24438424 )
2014
33
Delayed Brain Infarction due to Bilateral Vertebral Artery Occlusion Which Occurred 5 Days after Cervical Trauma. ( 25328652 )
2014
34
Evaluation of Rotational Vertebral Artery Occlusion Using Ultrasound Facilitates the Detection of Arterial Dissection in the Atlas Loop. ( 25307799 )
2014
35
Rotational vertebral artery occlusion secondary to adjacent-level degeneration following anterior cervical discectomy and fusion. ( 24745352 )
2014
36
Upbeat nystagmus during head rotation in rotational vertebral artery occlusion. ( 24691903 )
2014
37
Atypical Anterior Spinal Artery Infarction due to Left Vertebral Artery Occlusion Presenting with Bilateral Hand Weakness. ( 24829605 )
2014
38
Endovascular reconstruction of vertebral artery occlusion prior to basilar thrombectomy in a series of six patients presenting with acute symptomatic basilar thrombosis. ( 23737492 )
2013
39
Coronary subclavian steal from a left internal thoracic artery coronary bypass graft due to ipsilateral subclavian artery stenosis and an arteriovenous graft in a hemodialysis patient with left vertebral artery occlusion. ( 23728554 )
2013
40
Rotational vertebral artery occlusion associated with occipitoatlantal assimilation, atlantoaxial subluxation, and basilar impression. ( 23287744 )
2013
41
Traumatic, high-cervical, coronal-plane spondyloptosis with unilateral vertebral artery occlusion: treatment using a prophylactic arterial bypass graft, open reduction, and instrumented segmental fusion. ( 24286529 )
2013
42
Osteochondroma of C1 causing vertebral artery occlusion. ( 22844969 )
2013
43
A Ruptured Aneurysm Arising at the Leptomeningeal Collateral Circulation from the Extracranial Vertebral Artery to the Posterior Inferior Cerebellar Artery Associated with Bilateral Vertebral Artery Occlusion. ( 24321776 )
2013
44
Bilateral mechanical rotational vertebral artery occlusion. ( 23465174 )
2013
45
Impact of contralateral carotid or vertebral artery occlusion in patients undergoing carotid endarterectomy or carotid artery stenting. ( 24360588 )
2013
46
Endovascular angioplasty for extracranial vertebral artery occlusion without visualization of the stump of the artery ostium. ( 23803622 )
2013
47
Rotational vertebral artery occlusion: mechanisms and long-term outcome. ( 23696552 )
2013
48
Death due to extensive cervicomedullary infarction following iatrogenic vertebral artery occlusion. ( 22350824 )
2012
49
Stenting of a symptomatic long-segment extracranial vertebral artery occlusion. ( 21990790 )
2011
50
Traumatic Carotid Artery Dissection and Bilateral Vertebral Artery Occlusion after a Horse Attack: An Unusual Combination and Etiology. ( 21830193 )
2011

Variations for Vertebral Artery Occlusion

Expression for Vertebral Artery Occlusion

Search GEO for disease gene expression data for Vertebral Artery Occlusion.

Pathways for Vertebral Artery Occlusion

Pathways related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.58 F3 FOSB NOS2
2 11.34 BDNF NTRK2 SST
3 9.77 BDNF NTRK2

GO Terms for Vertebral Artery Occlusion

Biological processes related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron apoptotic process GO:0043524 9.33 AARS BDNF NTRK2
2 cytokine-mediated signaling pathway GO:0019221 9.26 CSF2 F3 NOS2 SOCS2
3 brain-derived neurotrophic factor receptor signaling pathway GO:0031547 8.62 BDNF NTRK2

Sources for Vertebral Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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