MCID: VRT001
MIFTS: 33

Vertebral Artery Occlusion

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Vertebral Artery Occlusion

MalaCards integrated aliases for Vertebral Artery Occlusion:

Name: Vertebral Artery Occlusion 12 15 72
Occlusion and Stenosis of Vertebral Artery 12 33

Classifications:



External Ids:

Disease Ontology 12 DOID:11299
ICD9CM 35 433.2
ICD10 33 I65.0
UMLS 72 C0155724 C0265104

Summaries for Vertebral Artery Occlusion

MalaCards based summary : Vertebral Artery Occlusion, also known as occlusion and stenosis of vertebral artery, is related to basilar artery occlusion and vertebrobasilar insufficiency. An important gene associated with Vertebral Artery Occlusion is GALT (Galactose-1-Phosphate Uridylyltransferase), and among its related pathways/superpathways are Beta-Adrenergic Signaling and IL-1 Family Signaling Pathways. Affiliated tissues include brain, testes and spinal cord, and related phenotypes are growth/size/body region and homeostasis/metabolism

Related Diseases for Vertebral Artery Occlusion

Diseases related to Vertebral Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Related Disease Score Top Affiliating Genes
1 basilar artery occlusion 30.1 SLC25A16 PLG FOSB
2 vertebrobasilar insufficiency 10.6
3 conjugate gaze palsy 10.5 PLG F3
4 cerebral falx meningioma 10.5 PLG F3
5 intestinal impaction 10.4 PLG F3
6 leech infestation 10.4 PLG F3
7 cerebral arterial disease 10.4 SLC25A16 MRAS
8 partial motor epilepsy 10.4 RBFOX3 F3
9 giant hemangioma 10.4 PLG F3
10 femoral neuropathy 10.4 PLG F3
11 blue toe syndrome 10.4 PLG F3
12 nodular ganglioneuroblastoma 10.4 NTRK2 BDNF
13 bow hunter's stroke 10.4
14 aneurysm 10.4
15 anterior cranial fossa meningioma 10.4 PLG F3
16 korean hemorrhagic fever 10.4 PLG F3
17 hemometra 10.3 SLC25A16 F3
18 dysbaric osteonecrosis 10.3 PLG F3
19 intracranial thrombosis 10.3 PLG F3
20 lemierre's syndrome 10.3 SLC25A16 PLG F3
21 pica disease 10.3
22 pathologic nystagmus 10.3
23 syncope 10.3
24 endocardium disease 10.2 PLG F3
25 carotid artery thrombosis 10.2 F3 CSF2
26 cerebrovascular disease 10.2
27 intermediate coronary syndrome 10.2 PLG F3
28 ataxia and polyneuropathy, adult-onset 10.2
29 lateral medullary syndrome 10.2
30 headache 10.2
31 mucopolysaccharidosis, type ii 10.1
32 stroke, ischemic 10.1
33 subclavian steal syndrome 10.1
34 exostosis 10.1
35 brain stem infarction 10.1
36 head injury 10.1
37 hepatic vascular disease 10.1 SST PLG F3
38 vein disease 10.0 SST PLG F3
39 pulmonary artery disease 10.0 PLG F3
40 status epilepticus 10.0 SST NTRK2 BDNF
41 spondylosis, cervical 10.0
42 hydrocephalus 10.0
43 locked-in syndrome 10.0
44 vertebral artery insufficiency 10.0
45 vascular disease 10.0
46 transient cerebral ischemia 10.0
47 spondylosis 10.0
48 cranial nerve palsy 10.0
49 intracranial embolism 10.0
50 congenital hydrocephalus 10.0

Graphical network of the top 20 diseases related to Vertebral Artery Occlusion:



Diseases related to Vertebral Artery Occlusion

Symptoms & Phenotypes for Vertebral Artery Occlusion

MGI Mouse Phenotypes related to Vertebral Artery Occlusion:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.2 BDNF CBSL CSF2 F3 FOSB GALT
2 homeostasis/metabolism MP:0005376 10.13 BDNF CBSL CSF2 F3 GALT NOS2
3 endocrine/exocrine gland MP:0005379 10.08 BDNF CBSL CSF2 GALT NOS2 NTRK2
4 immune system MP:0005387 10.06 CBSL CSF2 F3 GALT MRAS NOS2
5 nervous system MP:0003631 9.96 BDNF CBSL CSF2 F3 FOSB GALT
6 integument MP:0010771 9.91 BDNF CBSL CSF2 F3 NOS2 PLG
7 liver/biliary system MP:0005370 9.8 CBSL GALT NOS2 NTRK2 PLG SOCS2
8 reproductive system MP:0005389 9.76 BDNF CBSL CSF2 GALT NOS2 NTRK2
9 respiratory system MP:0005388 9.56 BDNF CBSL CSF2 F3 NOS2 NTRK2
10 vision/eye MP:0005391 9.17 BDNF CBSL F3 GJA8 NOS2 NTRK2

Drugs & Therapeutics for Vertebral Artery Occlusion

Search Clinical Trials , NIH Clinical Center for Vertebral Artery Occlusion

Genetic Tests for Vertebral Artery Occlusion

Anatomical Context for Vertebral Artery Occlusion

MalaCards organs/tissues related to Vertebral Artery Occlusion:

41
Brain, Testes, Spinal Cord, Bone

Publications for Vertebral Artery Occlusion

Articles related to Vertebral Artery Occlusion:

(show top 50) (show all 337)
# Title Authors PMID Year
1
Prevention of Thromboembolic Infarction After Surgery for Traumatic Cervical Fracture with Vertebral Artery Occlusion by Preoperative Endovascular Coil Embolization. 38
31207373 2019
2
Traumatic posterior atlantoaxial dislocation with associated C1 Jefferson fracture and bilateral vertebral artery occlusion without odontoid process fracture or neurological deficit. 38
29961910 2019
3
Successful endovascular coil embolisation of a ruptured V1-segment vertebral artery dissecting aneurysm making a fistula with the adjacent vein. 38
31171534 2019
4
Steroid refractory giant cell arteritis with bilateral vertebral artery occlusion and middle cerebellar peduncle infarction. 38
31188339 2019
5
Resolution of Hypoxic Tissue in Cerebellar Hemispheres After Arterial Bypass Surgery in a Patient With Symptomatic Bilateral Vertebral Artery Occlusion: A 18F-FRP170 PET Study. 38
30688740 2019
6
Rotational vertebral artery occlusion secondary to completely extraosseous vertebral artery. 38
30619984 2019
7
Bilateral vertebral artery occlusion after cervical spine fracture dislocation. 38
30684719 2019
8
Rotational vertebral artery occlusion in a patient with basilar invagination. 38
30652932 2019
9
Intravenous Thrombolysis in Posterior Circulation Stroke. 38
31080436 2019
10
Compression Syndromes of the Vertebral Artery at the Craniocervical Junction. 38
30610316 2019
11
Bithalamic Infarction (Artery of Percheron Occlusion) after Anterior Cervical Discectomy and Fusion. 38
31011457 2019
12
Fine margin between crossed sensory and contralateral sensory loss: A case report. 38
29937417 2018
13
Bidirectional Transradial and Transfemoral Approach for Stent-Assisted Coil Embolization of Right Subclavian Artery Saccular Aneurysm. 38
29716478 2018
14
C2-C3 Anterior Cervical Arthrodesis in the Treatment of Bow Hunter's Syndrome: Case Report and Review of the Literature. 38
30053560 2018
15
Coil Embolization through Collateral Pathway for Ruptured Vertebral Artery Dissecting Aneurysm with Bilateral Vertebral Artery Occlusion. 38
29914759 2018
16
Resolution of traumatic bilateral vertebral artery injury. 38
29497851 2018
17
Favorable Long-Term Outcomes for Positional Vertebral Artery Occlusion with Treatment Strategy Prioritizing Spinal Fusion Surgery. 38
29572170 2018
18
Vertebral Artery Occlusion Causing Facial Colliculus and Opalski Stroke Syndromes Simultaneously. 38
29722745 2018
19
The role of argon in stroke. 38
30112168 2018
20
Successful retrograde recanalization of acute right dominant vertebral artery occlusion through the left posterior communicating artery in a patient with acute vertebrobasilar ischemic stroke. 38
29682138 2018
21
Cerebellar infarction after posterior direct reduction and fixation to treat an unstable Jefferson fracture: a case report. 38
29307021 2018
22
Vertebral Artery Stump Syndrome. 38
29151515 2018
23
Clinical significance of reversal of flow in the vertebral artery identified on cerebrovascular duplex ultrasound. 38
28935292 2018
24
Iatrogenic Vascular Injuries Due to Spinal Surgeries: Endovascular Perspective. 38
28191625 2018
25
Awareness of traumatic occult lateral mass fracture of the cervical spine triggered by the presence of unilateral vertebral artery occlusion: a case report. 38
29560277 2018
26
Two-stage corrective surgery for severe rigid cervical kyphotic deformity with unilateral vertebral artery occlusion after old blunt trauma: a case report. 38
29531796 2018
27
A Case of Medullary Infarction Presented Initial Symptoms Similar to Meniere's Disease. 38
29036757 2018
28
A young woman with traumatic vertebral artery occlusion: a case report. 38
30386540 2018
29
Rotational Vertebral Artery Dissection Secondary to Anomalous Entrance into Transverse Foramen. 38
28943421 2017
30
Temporary vertebral artery occlusion after C3 fracture dislocation injury and spontaneous resolution following reduction and instrumented fusion: case report and literature review. 38
27798854 2017
31
Combined Use of Intraoperative Indocyanine Green and Dynamic Angiography in Rotational Vertebral Artery Occlusion. 38
29114306 2017
32
Vertebral artery occlusion after anterior cervical discectomy with fusion. 38
29736229 2017
33
Multimodal Therapy for Non-Superacute Vertebral Basilar Artery Occlusion. 38
29118803 2017
34
The Dual Role of Cerebral Autoregulation and Collateral Flow in the Circle of Willis After Major Vessel Occlusion. 38
27831856 2017
35
Bow Hunter's Syndrome: Surgical Management (Video) and Review of the Literature. 38
28450231 2017
36
Rapid Progression of Vertebral Artery Occlusion After Radiotherapy for Nasopharyngeal Carcinoma. 38
29250760 2017
37
Evaluation of a Traumatic Vertebral Artery Occlusion. 38
28254602 2017
38
Endovascular vs. medical therapy in symptomatic vertebral artery stenosis: a meta-analysis. 38
27544500 2017
39
Ocular Manifestation of a Cervical Spine Injury: An Adult Case of Traumatic Atlantoaxial Rotatory Subluxation Manifesting with Nystagmus. 38
28254538 2017
40
Cryptic Recanalization of Chronic Vertebral Artery Occlusion by Head Rotation. 38
28117210 2017
41
Atlantoaxial Stabilization Using C1 and C2 Laminar Screw Fixation. 38
28443177 2017
42
Posterior Fossa Craniectomy with Endovascular Therapy of Giant Fusiform Basilar Artery Aneurysms: A New Approach to Consider? 38
27810459 2017
43
Bilateral Subaxial Rotational Vertebral Artery Occlusion in a Setting of a Prior Cervical Construct. 38
27609452 2017
44
Endovascular Management of a Combined Subclavian and Vertebral Artery Injury in an Unstable Polytrauma Patient: Case Report and Literature Review. 38
28246625 2017
45
Vertebral Artery Occlusion and Recanalization After Cervical Facet Dislocation. 38
27535628 2016
46
Large animal canine endovascular ischemic stroke models: A review. 38
27496066 2016
47
Bilateral vertebral artery occlusion without headache in giant cell arteritis. 38
27508209 2016
48
Combined use of intraoperative indocyanine green and dynamic angiography in rotational vertebral artery occlusion. 38
27041076 2016
49
Preoperative catheter spinal angiography and embolization of cervical spinal tumors: Outcomes from a single center. 38
27020696 2016
50
Therapeutic internal carotid or vertebral artery occlusion using the WEB device. 38
26861025 2016

Variations for Vertebral Artery Occlusion

Expression for Vertebral Artery Occlusion

Search GEO for disease gene expression data for Vertebral Artery Occlusion.

Pathways for Vertebral Artery Occlusion

GO Terms for Vertebral Artery Occlusion

Biological processes related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 activation of phospholipase C activity GO:0007202 9.26 NTRK2 BDNF
2 neurotrophin TRK receptor signaling pathway GO:0048011 9.16 NTRK2 BDNF
3 positive regulation of non-membrane spanning protein tyrosine kinase activity GO:1903997 8.96 NTRK2 BDNF
4 brain-derived neurotrophic factor receptor signaling pathway GO:0031547 8.62 NTRK2 BDNF

Sources for Vertebral Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....