MCID: VRT003
MIFTS: 31

Vertebrobasilar Insufficiency

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Vertebrobasilar Insufficiency

MalaCards integrated aliases for Vertebrobasilar Insufficiency:

Name: Vertebrobasilar Insufficiency 12 43 15 17 71
Vertebrobasilar Arterial Insufficiency 12
Vertebrobasilar Artery Syndrome 12
Vertebro-Basilar Insufficiency 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13003
ICD9CM 34 435.3
MeSH 43 D014715
SNOMED-CT 67 64009001
ICD10 32 G45.0
UMLS 71 C0042568

Summaries for Vertebrobasilar Insufficiency

MalaCards based summary : Vertebrobasilar Insufficiency, also known as vertebrobasilar arterial insufficiency, is related to subclavian steal syndrome and pathologic nystagmus. An important gene associated with Vertebrobasilar Insufficiency is GGT1 (Gamma-Glutamyltransferase 1). The drugs Paclitaxel and Albumin-Bound Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and cerebellum.

Wikipedia : 74 Vertebrobasilar insufficiency (VBI) describes a temporary set of symptoms due to decreased blood flow... more...

Related Diseases for Vertebrobasilar Insufficiency

Diseases related to Vertebrobasilar Insufficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 98)
# Related Disease Score Top Affiliating Genes
1 subclavian steal syndrome 11.7
2 pathologic nystagmus 10.5
3 spondylosis, cervical 10.4
4 spondylosis 10.4
5 basilar artery insufficiency 10.3
6 syncope 10.3
7 vertebral artery occlusion 10.3
8 ataxia and polyneuropathy, adult-onset 10.2
9 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
10 cerebrovascular disease 10.2
11 spondyloarthropathy 1 10.2
12 meniere disease 10.2
13 neurofibromatosis, type iv, of riccardi 10.2
14 hydrocephalus 10.2
15 inflammatory spondylopathy 10.2
16 carotid stenosis 10.2
17 normal pressure hydrocephalus 10.2
18 arteriosclerosis 10.2
19 mutism 10.2
20 akinetic mutism 10.2
21 spondylitis 10.2
22 capgras syndrome 10.2
23 subacute delirium 10.2
24 yemenite deaf-blind hypopigmentation syndrome 10.1
25 branchiootic syndrome 1 10.1
26 pica disease 10.1
27 vascular disease 10.1
28 exostosis 10.1
29 carotid artery disease 10.1
30 vulvovaginal candidiasis 10.1 SKAP2 GGT1
31 atherosclerosis susceptibility 10.1
32 sleep apnea 10.1
33 sensorineural hearing loss 10.1
34 amnestic disorder 10.1
35 cortical blindness 10.1
36 vertebral artery insufficiency 10.1
37 basilar artery occlusion 10.1
38 vestibular nystagmus 10.1
39 encephalomalacia 10.1
40 transient cerebral ischemia 10.1
41 bow hunter's stroke 10.1
42 rare surgical neurologic disease 10.1
43 migraine with or without aura 1 10.0
44 narcolepsy 10.0
45 hypersomnia 10.0
46 hepatic vascular disease 9.9 GGT1 EDN1
47 cardiac arrhythmia 9.9
48 deafness, unilateral 9.9
49 hypercholesterolemia, familial, 1 9.9
50 rheumatoid arthritis 9.9

Graphical network of the top 20 diseases related to Vertebrobasilar Insufficiency:



Diseases related to Vertebrobasilar Insufficiency

Symptoms & Phenotypes for Vertebrobasilar Insufficiency

Drugs & Therapeutics for Vertebrobasilar Insufficiency

Drugs for Vertebrobasilar Insufficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2, Phase 3 33069-62-4 36314
2 Albumin-Bound Paclitaxel Phase 2, Phase 3
3
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
4
Everolimus Approved Phase 2 159351-69-6 6442177 70789204
5 Complement C3

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 A Randomized Trial for Treatment of Symptomatic Extracranial Vertebral Artery Stenosis: Drug Eluting Stents Versus Bare Metal Stents Completed NCT03201432 Phase 2, Phase 3
2 Prospective Multi-center Single-arm Target Value Clinical Trial for Evaluating Clinical Use Safety and Efficacy of the Firehorus Vertebral Artery Rapamycin-target-eluting Stent System Unknown status NCT02328781 Phase 2
3 Drug-coated Balloon Angioplasty for Patients With Symptomatic Vertebral Artery Stenosis Recruiting NCT03504657 Phase 2
4 Clinical Results and Restenosis Analysis of Symptomatic Ostial Vertebral Artery Stenosis Treated With Tubular Coronary Stents Unknown status NCT00172458
5 Remote Ischemic Conditioning for Reducing Stroke Risk of Symptomatic Vertebrobasilar Lesion of Atherosclerosis Unknown status NCT02971462
6 Effects of High Inspiratory Oxygen on Cerebral Tissue Oxygenation and Patient Recovery After Carotid Endarterectomy Completed NCT02991976
7 The Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS) Study Completed NCT00590980
8 Comparison the Effects of Manual and Instrumental Chiropractic Spinal Manipulation on Vertebrobasilar and Internal Carotis Arteries in Healthy Population Completed NCT03435159
9 Immediate Effect of a Single Cervical Spinal Manipulation on Cervical Movement Pattern Completed NCT04059692
10 Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER) Recruiting NCT03999983
11 Outpatient Office Based Endovascular Procedures Enrolling by invitation NCT04054440
12 Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke II (VERiTASII) Not yet recruiting NCT03729817

Search NIH Clinical Center for Vertebrobasilar Insufficiency

Cochrane evidence based reviews: vertebrobasilar insufficiency

Genetic Tests for Vertebrobasilar Insufficiency

Anatomical Context for Vertebrobasilar Insufficiency

MalaCards organs/tissues related to Vertebrobasilar Insufficiency:

40
Brain, Cortex, Cerebellum, Thalamus, Pons, Testes, Bone

Publications for Vertebrobasilar Insufficiency

Articles related to Vertebrobasilar Insufficiency:

(show top 50) (show all 817)
# Title Authors PMID Year
1
Magnetic resonance angiography and transcranial Doppler ultrasound findings in patients with a clinical diagnosis of vertebrobasilar insufficiency. 61
31967281 2020
2
Left Vertebral Artery to Common Carotid Artery Transposition in a Patient With Bilateral Vertebral Insufficiency: 3-Dimensional Operative Video. 61
31980819 2020
3
Positional transient loss of consciousness and hemispheric deficits in the setting of severe four-vessel extracranial cerebrovascular disease. 61
31737804 2019
4
Should we abandon positional testing for vertebrobasilar insufficiency? 61
31767531 2019
5
Comparative effectiveness of Ginkgo injections for treating vertebrobasilar insufficiency: A systematic review and network meta-analysis. 61
31746018 2019
6
Persistent trigeminal artery in a patient with posterior circulation stroke treated with rt-PA: case report. 61
31656167 2019
7
Sixth Cranial Nerve Palsy and Vertigo Caused by Vertebrobasilar Insufficiency. 61
31591859 2019
8
Internal Thoracic Artery to Vertebral Artery Bypass Surgery: A Cadaveric Feasibility Study. 61
31284060 2019
9
Vertebrobasilar ischemia (VBI) related neuro-ophthalmic syndromes after routine activities involving hyperextension or rotation of the neck (hairdresser syndrome). 61
31570813 2019
10
Comorbidity clusters in generalized osteoarthritis among female patients: A cross-sectional study. 61
31522761 2019
11
Rare cause of Bow Hunter's syndrome due to an aberrant course of a vertebral artery. 61
31340945 2019
12
Extracranial-to-Intracranial Bypass for Refractory Vertebrobasilar Insufficiency. 61
30926554 2019
13
[SERUM CONTENTS OF SUBSTANCE P, ENDOTHELIN-1 AND VASOACTIVE INTESTINAL PEPTIDE IN CHILDREN WITH RECURRENT BRONCHITIS AND VERTEBROBASILAR INSUFFICIENCY]. 61
31322514 2019
14
Arcuate foramen: "Anatomical variation shape or adaptation legacy?" 61
30656416 2019
15
Carotid-vertebral artery bypass with saphenous vein graft for symptomatic vertebrobasilar insufficiency. 61
30717073 2019
16
Bow Hunter Syndrome with Associated Pseudoaneurysm. 61
30463807 2019
17
Possible role for glucagon in the control of Paget's disease of bone. 61
30683679 2019
18
Compression Syndromes of the Vertebral Artery at the Craniocervical Junction. 61
30610316 2019
19
Bilateral vertebral artery occlusion after cervical spine fracture dislocation. 61
30684719 2019
20
Significance of Provocative Perfusion Computed Tomography for Evaluation of Bow Hunter Syndrome. 61
30261398 2019
21
Unstable os odontoideum contributing to cervical myelopathy and obstructive sleep apnea. 61
31528461 2019
22
Atheroma of the Innominate Artery Presenting as a Transient Ischemic Attack. 61
30956913 2019
23
[Comparative analysis of results of revascularization of the first segment of vertebral arteries]. 61
31149996 2019
24
Bow Hunter's Syndrome: Surgical Vertebral Artery Decompression Guided by Dynamic Intraoperative Angiography. 61
30059781 2018
25
Percutaneous endovascular therapy for symptomatic chronic total occlusion of the left subclavian artery. 61
29546434 2018
26
Emergency Superficial Temporal Artery-Superior Cerebellar Artery Bypass for the Refractory Vertebrobasilar Insufficiency with Partial Mastoidectomy. 61
30010066 2018
27
Risk of posterior circulation stroke in patients with cervical spondylosis: A nationwide, population-based study. 61
30172083 2018
28
C2-C3 Anterior Cervical Arthrodesis in the Treatment of Bow Hunter's Syndrome: Case Report and Review of the Literature. 61
30053560 2018
29
Anomalous left subclavian artery from the pulmonary artery in a neonate. 61
29860892 2018
30
An attempt to measure the diametric relationship between slow and quick phases of nystagmus. 61
29355067 2018
31
FEATURES OF HEMODYNAMICS IN VERTEBROBASILAR ARTERIAL SYSTEM IN YOUNG PEOPLE, DEPENDING ON BIOMECHANICAL DISORDERS OF THE MUSCULOSKELETAL SYSTEM. 61
30204094 2018
32
The oculomotor-tentorial triangle. Part 2: a microsurgical workspace for vascular lesions in the crural and ambient cisterns. 61
29957110 2018
33
Vertebrobasilar Artery Stroke as the Heralding Sign of Systemic Lupus Erythematosus. 61
29306594 2018
34
Beauty parlor stroke syndrome due to a bone fragment from an osteophyte of the atlas: case report. 61
29372864 2018
35
Pathogenetic Role of Endothelial Dysfunction in Idiopathic Vestibulopathy. 61
29658088 2018
36
Subclavian-to-Extracranial Vertebral Artery Bypass in a Patient With Vertebrobasilar Insufficiency: 3-Dimensional Operative Video. 61
28973539 2018
37
[Non-drug therapy of vertigo]. 61
30251976 2018
38
[Efficacy of carotid endarterectomy in patients with vertebrobasilar insufficiency without significant lesion of vertebral arteries]. 61
30531777 2018
39
[Clinical efficacy of reconstructive operations on the third (V3) segment of the vertebral artery]. 61
29688207 2018
40
Bow Hunter's Syndrome in a Patient with a Right Hypoplastic Vertebral Artery and a Dynamically Compressible Left Vertebral Artery. 61
29492144 2018
41
Determinants of long-term outcome in patients after percutaneous stent-assisted management of symptomatic subclavian or innominate artery stenosis or occlusion. 61
28846540 2017
42
Rotational Vertebral Artery Dissection Secondary to Anomalous Entrance into Transverse Foramen. 61
28943421 2017
43
FEATURES OF FORMATION OF COLLATERAL CIRCULATION IN PATIENTS WITH SUBCLAVIAN STEAL SYNDROME. 61
29328023 2017
44
Acupuncture for vertebrobasilar insufficiency vertigo: Protocol for a systematic review and meta-analysis. 61
29390369 2017
45
Hybrid Technique for the Treatment of Refractory Vertebrobasilar Insufficiencies. 61
28843759 2017
46
Internal Maxillary Artery to Upper Posterior Circulation Bypass Using a Superficial Temporal Artery Graft: Surgical Anatomy and Feasibility Assessment. 61
28826714 2017
47
Occipital Artery to Anterior Inferior Cerebellar Artery Bypass with Radial Artery Interposition Graft for Vertebrobasilar Insufficiency: 3-Dimensional Operative Video. 61
28922887 2017
48
Combined Use of Intraoperative Indocyanine Green and Dynamic Angiography in Rotational Vertebral Artery Occlusion. 61
29114306 2017
49
Surgical Treatment of Rotational Vertebral Artery Syndrome Induced by Spinal Tumor: A Case Report and Literature Review. 61
29018650 2017
50
Bow hunter's syndrome in a patient with vertebral artery atresia, an arcuate foramen, and unilateral deafness: a case report. 61
28828133 2017

Variations for Vertebrobasilar Insufficiency

Expression for Vertebrobasilar Insufficiency

Search GEO for disease gene expression data for Vertebrobasilar Insufficiency.

Pathways for Vertebrobasilar Insufficiency

GO Terms for Vertebrobasilar Insufficiency

Sources for Vertebrobasilar Insufficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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