MCID: VRT003
MIFTS: 30

Vertebrobasilar Insufficiency

Categories: Neuronal diseases, Cardiovascular diseases

Aliases & Classifications for Vertebrobasilar Insufficiency

MalaCards integrated aliases for Vertebrobasilar Insufficiency:

Name: Vertebrobasilar Insufficiency 12 44 15 73
Vertebrobasilar Arterial Insufficiency 12
Vertebrobasilar Artery Syndrome 12
Vertebro-Basilar Insufficiency 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13003
ICD10 33 G45.0
ICD9CM 35 435.3
MeSH 44 D014715
UMLS 73 C0042568

Summaries for Vertebrobasilar Insufficiency

MalaCards based summary : Vertebrobasilar Insufficiency, also known as vertebrobasilar arterial insufficiency, is related to subclavian steal syndrome and cervicitis. An important gene associated with Vertebrobasilar Insufficiency is ADGRE2 (Adhesion G Protein-Coupled Receptor E2). The drugs Paclitaxel and Albumin-Bound Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include thalamus, brain and cerebellum.

Wikipedia : 76 Vertebrobasilar insufficiency (VBI) or vertebral-basilar ischemia, also called beauty parlour syndrome... more...

Related Diseases for Vertebrobasilar Insufficiency

Diseases related to Vertebrobasilar Insufficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 27)
# Related Disease Score Top Affiliating Genes
1 subclavian steal syndrome 11.1
2 cervicitis 10.3
3 vertebral artery occlusion 10.1
4 spondylosis 10.1
5 cerebritis 10.1
6 rheumatoid arthritis 9.9
7 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.9
8 arthritis 9.9
9 dementia 9.9
10 thyroiditis 9.9
11 hypersomnia 9.9
12 atlantoaxial subluxation 9.9
13 alzheimer disease 9.8
14 muscle hypertrophy 9.8
15 achromatopsia 9.8
16 insulinoma 9.8
17 sensorineural hearing loss 9.8
18 thoracic outlet syndrome 9.8
19 ischemia 9.8
20 radiculopathy 9.8
21 vascular dementia 9.8
22 carotid artery dissection 9.8
23 binswanger's disease 9.8
24 bow hunter's stroke 9.8
25 sudden sensorineural hearing loss 9.8
26 aneurysm 9.8
27 right aortic arch 9.8

Graphical network of the top 20 diseases related to Vertebrobasilar Insufficiency:



Diseases related to Vertebrobasilar Insufficiency

Symptoms & Phenotypes for Vertebrobasilar Insufficiency

Drugs & Therapeutics for Vertebrobasilar Insufficiency

Drugs for Vertebrobasilar Insufficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2, Phase 3 33069-62-4 36314
2 Albumin-Bound Paclitaxel Phase 2, Phase 3
3
Everolimus Approved Phase 2 159351-69-6 6442177
4
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Drug Eluting Stents Versus Bare Metal Stents for Treatment of Symptomatic Extracranial Vertebral Artery Stenosis Completed NCT03201432 Phase 2, Phase 3
2 Prospective Evaluation of Safety and Efficacy Vertebral Drug-eluting Stent System Unknown status NCT02328781 Phase 2
3 Drug-coated Balloon Angioplasty for Patients With Symptomatic Vertebral Artery Stenosis Recruiting NCT03504657 Phase 2
4 Clinical Results and Restenosis Analysis of Symptomatic Ostial Vertebral Artery Stenosis Treated With Tubular Coronary Stents Unknown status NCT00172458
5 Effects of Spinal Manipulation on Vertebrobasilar and Internal Carotis Arteries in Healthy Population Completed NCT03435159 Not Applicable
6 Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS) Completed NCT00590980
7 Oxygen Concentration and Recovery After Carotid Endarterectomy Completed NCT02991976 Not Applicable
8 Differential Diagnosis for the Causes of Subclavian Steal for Patients With Vascular Access in the Forearm Completed NCT01263301 Not Applicable
9 Remote Ischemic Conditioning for Reducing Stroke Risk of Symptomatic Vertebrobasilar Lesion of Atherosclerosis Not yet recruiting NCT02971462 Not Applicable

Search NIH Clinical Center for Vertebrobasilar Insufficiency

Cochrane evidence based reviews: vertebrobasilar insufficiency

Genetic Tests for Vertebrobasilar Insufficiency

Anatomical Context for Vertebrobasilar Insufficiency

MalaCards organs/tissues related to Vertebrobasilar Insufficiency:

41
Thalamus, Brain, Cerebellum, Pons, Cortex, Testes, Thyroid

Publications for Vertebrobasilar Insufficiency

Articles related to Vertebrobasilar Insufficiency:

(show top 50) (show all 130)
# Title Authors Year
1
Vertebrobasilar Insufficiency ( 29489229 )
2018
2
Vertebrobasilar Insufficiency Due to Distal Posterior Inferior Cerebellar Artery Compression in Chiari 1.5. ( 28583457 )
2017
3
Congenital Bilateral C2 Transverse Foramina Stenosis Causing Adult-Onset Vertebrobasilar Insufficiency and Posterior Circulation Stroke. ( 28626412 )
2017
4
Subclavian-to-Extracranial Vertebral Artery Bypass in a Patient With Vertebrobasilar Insufficiency: 3-Dimensional Operative Video. ( 28973539 )
2017
5
The association between vertebrobasilar insufficiency and the risk of dementia: a nationwide register-based retrospective cohort study in Taiwan. ( 28838901 )
2017
6
Acupuncture for vertebrobasilar insufficiency vertigo: Protocol for a systematic review and meta-analysis. ( 29390369 )
2017
7
The effect of chinese herbal medicine Banxia Baizhu Tianma Decoction for the treatment of vertebrobasilar insufficiency vertigo: A systematic review and meta-analysis of randomized controlled trials. ( 28434468 )
2017
8
Treatment of vertebrobasilar insufficiency due to stenosis and aneurysm of the vertebral artery. ( 28594803 )
2017
9
Occipital Artery to Anterior Inferior Cerebellar Artery Bypass with Radial Artery Interposition Graft for Vertebrobasilar Insufficiency: 3-Dimensional Operative Video. ( 28922887 )
2017
10
Pathophysiology and Diagnosis of Vertebrobasilar Insufficiency: A Review of the Literature. ( 28680502 )
2017
11
Vertebrobasilar insufficiency and gamma-glutamyltransferase: An emerging relationship demonstrating inflammation and atherosclerosis. ( 27546696 )
2016
12
Association of Sudden Sensorineural Hearing Loss With Vertebrobasilar Insufficiency. ( 27195937 )
2016
13
Rotational vertebrobasilar insufficiency due to compression of a persistent first intersegmental vertebral artery variant: case report. ( 27716015 )
2016
14
Radial Artery Bypass for Intractable Vertebrobasilar Insufficiency: Case Series and Review of the Literature. ( 26284960 )
2015
15
Are there any novel radiological diagnostic clues in magnetic resonance imaging for vertebrobasilar insufficiency? ( 26807367 )
2015
16
Clinical research of persimmon leaf extract and ginkgo biloba extract in the treatment of vertebrobasilar insufficiency. ( 25864752 )
2015
17
The comparative analyses of the auditory evoked potentials and color Doppler sonography findings in patients diagnosed with vertebrobasilar insufficiency. ( 24806547 )
2014
18
Insulinoma clinically misdiagnosed as vertebrobasilar insufficiency in an obese patient with recurrent episodes of loss of consciousness. ( 25062882 )
2014
19
Low scores on the Benton Facial Recognition Test associated with vertebrobasilar insufficiency. ( 23474072 )
2013
20
Diagnostic accuracy of premanipulative vertebrobasilar insufficiency tests: a systematic review. ( 23127991 )
2013
21
The effect of prostaglandin E1 on brainstem blood flow disturbance in an animal model of vertebrobasilar insufficiency. ( 23591797 )
2013
22
Diagnosis and management of vertebrobasilar insufficiency. ( 23378181 )
2013
23
Bow hunter's syndrome causing vertebrobasilar insufficiency in a young male with neck muscle hypertrophy: a case report and literature review. ( 24184499 )
2013
24
Cervical spondylosis: a rare and curable cause of vertebrobasilar insufficiency. ( 24000075 )
2013
25
The diagnosis of vertebrobasilar insufficiency using transcranial Doppler ultrasound. ( 23251187 )
2012
26
Evaluation of patients with vertigo of vertebrobasilar insufficiency origin using auditory brainstem response, electronystagmography, and transcranial Doppler. ( 22299665 )
2012
27
Isolated sudden hearing loss as a warning sign of vertebrobasilar insufficiency. ( 22892808 )
2012
28
The impact of laser irradiation on global stability in patients with vertebrobasilar insufficiency: a clinical report. ( 21873949 )
2011
29
The clinical reasoning of musculoskeletal physiotherapists in relation to the assessment of vertebrobasilar insufficiency: a qualitative study. ( 20381404 )
2010
30
Vertebrobasilar insufficiency due to right aortic arch with isolation of the left subclavian artery. ( 19198039 )
2009
31
Vertebrobasilar insufficiency presenting as isolated positional vertigo or dizziness: a double-blind retrospective cohort study. ( 19688845 )
2009
32
Giant cell arteritis revealed by vertebrobasilar insufficiency. ( 19208584 )
2009
33
Carotid artery dissection and vertebrobasilar insufficiency. ( 19584618 )
2009
34
Positional vertebral artery compression and vertebrobasilar insufficiency due to a herniated cervical disc. ( 19769514 )
2009
35
Surgical management of vertebrobasilar insufficiency due to pathology of the second-third segments of the vertebral artery. ( 20394339 )
2009
36
Multichannel computed tomography angiography and its role in the evaluation of rotational vertebrobasilar insufficiency. ( 18303305 )
2008
37
Forty-six cases of vertebrobasilar insufficiency treated by acupuncture plus intravenous infusion of ligustrazine. ( 19226890 )
2008
38
Is mechanical deformation of the suboccipital vertebral artery during cervical spine rotation responsible for vertebrobasilar insufficiency? ( 17624896 )
2008
39
Correlations of arterial hemodynamics with the severity of clinical manifestations of vertebrobasilar insufficiency. ( 19489320 )
2008
40
Rotational vertebrobasilar insufficiency due to dynamic compression of the dominant vertebral artery by the thyroid cartilage and occlusion of the contralateral vertebral artery at C1-2 level. ( 18298678 )
2008
41
Treatment of vertebrobasilar insufficiency--associated vertigo with a fixed combination of cinnarizine and dimenhydrinate. ( 18616088 )
2008
42
"Stretched loop sign" of the vertebral artery: a predictor of vertebrobasilar insufficiency in atlantoaxial dislocation. ( 16935639 )
2006
43
Endovascular treatment of supra-aortic extracranial stenoses in patients with vertebrobasilar insufficiency symptoms. ( 16718428 )
2006
44
Vertebrobasilar insufficiency. ( 16533485 )
2006
45
Comparison of vertebral artery velocity and flow volume measurements for diagnosis of vertebrobasilar insufficiency using color duplex sonography. ( 15837402 )
2005
46
Screening for vertebrobasilar insufficiency in patients with neck pain: manual therapy decision-making in the presence of uncertainty. ( 15966541 )
2005
47
Reactivity of rat basilar artery to serotonin after short-term ischemia of hindbrain and during chronic vertebrobasilar insufficiency. ( 16027866 )
2005
48
The role of SPECT imaging in the diagnosis of vertebrobasilar insufficiency. ( 15753788 )
2005
49
Clinical diagnosis of vertebrobasilar insufficiency: resident's case problem. ( 16294985 )
2005
50
Betahistine in vertebrobasilar insufficiency. ( 15732521 )
2004

Variations for Vertebrobasilar Insufficiency

Expression for Vertebrobasilar Insufficiency

Search GEO for disease gene expression data for Vertebrobasilar Insufficiency.

Pathways for Vertebrobasilar Insufficiency

GO Terms for Vertebrobasilar Insufficiency

Sources for Vertebrobasilar Insufficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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