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MCID: VSC025
MIFTS: 17
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Vesicoureteral Reflux 3
Categories:
Genetic diseases, Fetal diseases, Rare diseases
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MalaCards integrated aliases for Vesicoureteral Reflux 3:
Characteristics:HPO:32Classifications: |
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UniProtKB/Swiss-Prot
:
75
Vesicoureteral reflux 3: A disease belonging to the group of congenital anomalies of the kidney and urinary tract. It is characterized by the reflux of urine from the bladder into the ureters and sometimes into the kidneys, and is a risk factor for urinary tract infections. Primary disease results from a developmental defect of the ureterovesical junction. In combination with intrarenal reflux, the resulting inflammatory reaction may result in renal injury or scarring, also called reflux nephropathy. Extensive renal scarring impairs renal function and may predispose patients to hypertension, proteinuria, renal insufficiency and end-stage renal disease.
MalaCards based summary : Vesicoureteral Reflux 3, is also known as vur3. An important gene associated with Vesicoureteral Reflux 3 is SOX17 (SRY-Box 17). Affiliated tissues include kidney, and related phenotypes are hydroureter and vesicoureteral reflux
Description from OMIM:
613674
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Diseases in the Familial Vesicoureteral Reflux family:
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Symptoms via clinical synopsis from OMIM:57Clinical features from OMIM:613674Human phenotypes related to Vesicoureteral Reflux 3:32
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MalaCards organs/tissues related to Vesicoureteral Reflux 3:41
Kidney
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Genes related to Vesicoureteral Reflux 3 (1 elite genes):
- Elite gene
- Cancer Census gene in COSMIC
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UniProtKB/Swiss-Prot genetic disease variations for Vesicoureteral Reflux 3:75
ClinVar genetic disease variations for Vesicoureteral Reflux 3:6
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Search
GEO
for disease gene expression data for Vesicoureteral Reflux 3.
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