VUR3
MCID: VSC025
MIFTS: 21
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Vesicoureteral Reflux 3 (VUR3)
Categories:
Fetal diseases, Genetic diseases, Nephrological diseases, Rare diseases
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MalaCards integrated aliases for Vesicoureteral Reflux 3:
Characteristics:HPO:31Classifications:
MalaCards categories:
Global: Genetic diseases Fetal diseases Rare diseases Anatomical: Nephrological diseases |
UniProtKB/Swiss-Prot :
73
Vesicoureteral reflux 3: A disease belonging to the group of congenital anomalies of the kidney and urinary tract. It is characterized by the reflux of urine from the bladder into the ureters and sometimes into the kidneys, and is a risk factor for urinary tract infections. Primary disease results from a developmental defect of the ureterovesical junction. In combination with intrarenal reflux, the resulting inflammatory reaction may result in renal injury or scarring, also called reflux nephropathy. Extensive renal scarring impairs renal function and may predispose patients to hypertension, proteinuria, renal insufficiency and end-stage renal disease.
MalaCards based summary : Vesicoureteral Reflux 3, is also known as vur3. An important gene associated with Vesicoureteral Reflux 3 is SOX17 (SRY-Box Transcription Factor 17). Affiliated tissues include kidney, and related phenotypes are polyhydramnios and vesicoureteral reflux |
Diseases in the Familial Vesicoureteral Reflux family:
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Human phenotypes related to Vesicoureteral Reflux 3:31
Symptoms via clinical synopsis from OMIM:56Clinical features from OMIM:613674 |
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MalaCards organs/tissues related to Vesicoureteral Reflux 3:40
Kidney
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Articles related to Vesicoureteral Reflux 3:
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ClinVar genetic disease variations for Vesicoureteral Reflux 3:6
UniProtKB/Swiss-Prot genetic disease variations for Vesicoureteral Reflux 3:73
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Search
GEO
for disease gene expression data for Vesicoureteral Reflux 3.
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