MCID: VST005
MIFTS: 24

Vestibular Gland Benign Neoplasm

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Vestibular Gland Benign Neoplasm

MalaCards integrated aliases for Vestibular Gland Benign Neoplasm:

Name: Vestibular Gland Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060088

Summaries for Vestibular Gland Benign Neoplasm

Disease Ontology : 12 A female reproductive organ benign neoplasm that is located in the vestibular gland.

MalaCards based summary : Vestibular Gland Benign Neoplasm is related to minor vestibular glands adenoma and basaloid lung carcinoma. An important gene associated with Vestibular Gland Benign Neoplasm is PGR (Progesterone Receptor), and among its related pathways/superpathways are Proteoglycans in cancer and Gastric cancer. Affiliated tissues include vestibular gland, breast and ovary, and related phenotypes are limbs/digits/tail and neoplasm

Related Diseases for Vestibular Gland Benign Neoplasm

Diseases related to Vestibular Gland Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)
# Related Disease Score Top Affiliating Genes
1 minor vestibular glands adenoma 11.3
2 basaloid lung carcinoma 10.0 TP53 PGR
3 apocrine adenosis of breast 10.0 TP53 PGR
4 breast sarcoma 10.0 TP53 PGR
5 cervical adenoma malignum 10.0 TP53 PGR
6 peritoneal serous adenocarcinoma 10.0 TP53 PGR
7 primary peritoneal carcinoma 10.0 TP53 PGR
8 malignant spiradenoma 10.0 TP53 PGR
9 chordoid glioma 10.0 TP53 PGR
10 vulvar dystrophy 10.0 TP53 PGR
11 sweat gland benign neoplasm 10.0 TP53 PGR
12 papillary serous adenocarcinoma 10.0 TP53 PGR
13 pleomorphic carcinoma 10.0 TP53 PGR
14 papillary adenocarcinoma 9.9 TP53 PGR
15 oropharynx cancer 9.9 TP53 PGR
16 cervical adenocarcinoma 9.9 TP53 ESR1
17 serous cystadenocarcinoma 9.9 TP53 PGR
18 cystadenocarcinoma 9.9 TP53 PGR
19 carcinosarcoma 9.9 TP53 PGR
20 leiomyoma 9.9 PGR ESR1
21 uterine carcinosarcoma 9.9 TP53 PGR
22 ovarian serous cystadenocarcinoma 9.9 TP53 PGR
23 glassy cell carcinoma of the cervix 9.9 PGR ESR1
24 breast intraductal papillomatosis 9.9 PGR ESR1
25 familial ovarian cancer 9.9 TP53 ESR1
26 intraductal papilloma 9.9 PGR ESR1
27 nipple carcinoma 9.9 PGR ESR1
28 bartholin's gland adenoid cystic carcinoma 9.9 PGR ESR1
29 uterine corpus adenosarcoma 9.9 PGR ESR1
30 chronic tympanitis 9.9 PGR ESR1
31 granulomatous endometritis 9.9 PGR ESR1
32 endometritis 9.9 PGR ESR1
33 uterine body mixed cancer 9.9 TP53 ESR1
34 vulvar syringoma 9.9 PGR ESR1
35 lung leiomyoma 9.9 PGR ESR1
36 adult type testicular granulosa cell tumor 9.9 PGR ESR1
37 breast scirrhous carcinoma 9.9 PGR ESR1
38 oncocytic breast carcinoma 9.9 PGR ESR1
39 cervical clear cell adenocarcinoma 9.9 PGR ESR1
40 breast papillary carcinoma 9.9 PGR ESR1
41 papillary carcinoma 9.9 PGR ESR1
42 liver leiomyoma 9.9 PGR ESR1
43 intravenous leiomyomatosis 9.9 PGR ESR1
44 leiomyomatosis 9.9 PGR ESR1
45 breast adenoid cystic carcinoma 9.9 PGR ESR1
46 breast metaplastic carcinoma 9.9 PGR ESR1
47 intracranial meningioma 9.9 PGR ESR1
48 vulvar leiomyoma 9.9 PGR ESR1
49 breast adenoma 9.9 PGR ESR1
50 lipid-rich carcinoma 9.8 PGR ESR1

Graphical network of the top 20 diseases related to Vestibular Gland Benign Neoplasm:



Diseases related to Vestibular Gland Benign Neoplasm

Symptoms & Phenotypes for Vestibular Gland Benign Neoplasm

MGI Mouse Phenotypes related to Vestibular Gland Benign Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 limbs/digits/tail MP:0005371 9.33 ESR1 PGR TP53
2 neoplasm MP:0002006 9.13 ESR1 PGR TP53
3 no phenotypic analysis MP:0003012 8.8 ESR1 PGR TP53

Drugs & Therapeutics for Vestibular Gland Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Vestibular Gland Benign Neoplasm

Genetic Tests for Vestibular Gland Benign Neoplasm

Anatomical Context for Vestibular Gland Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Vestibular Gland Benign Neoplasm:

19
Vestibular Gland

MalaCards organs/tissues related to Vestibular Gland Benign Neoplasm:

40
Breast, Ovary, Lung, Cervix, Bone, Smooth Muscle, Liver

Publications for Vestibular Gland Benign Neoplasm

Variations for Vestibular Gland Benign Neoplasm

Expression for Vestibular Gland Benign Neoplasm

Search GEO for disease gene expression data for Vestibular Gland Benign Neoplasm.

Pathways for Vestibular Gland Benign Neoplasm

Pathways related to Vestibular Gland Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1 11.81 TP53 ESR1
2
Show member pathways
11.8 TP53 PGR ESR1
3 11.66 TP53 ESR1
4 11.6 PGR ESR1
5 11.52 TP53 ESR1
6
Show member pathways
11.44 PGR ESR1
7
Show member pathways
11.32 PGR ESR1
8
Show member pathways
11.15 PGR ESR1
9 10.88 TP53 ESR1
10 10.72 TP53 ESR1
11 10.17 TP53 ESR1

GO Terms for Vestibular Gland Benign Neoplasm

Cellular components related to Vestibular Gland Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin GO:0000785 8.8 TP53 PGR ESR1

Biological processes related to Vestibular Gland Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.54 TP53 PGR ESR1
2 negative regulation of gene expression GO:0010629 9.43 TP53 PGR ESR1
3 transcription initiation from RNA polymerase II promoter GO:0006367 9.4 PGR ESR1
4 steroid hormone mediated signaling pathway GO:0043401 9.32 PGR ESR1
5 negative regulation of production of miRNAs involved in gene silencing by miRNA GO:1903799 9.16 TP53 ESR1
6 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899 8.96 TP53 ESR1
7 intracellular steroid hormone receptor signaling pathway GO:0030518 8.62 PGR ESR1

Molecular functions related to Vestibular Gland Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 9.65 TP53 PGR ESR1
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.63 TP53 PGR ESR1
3 zinc ion binding GO:0008270 9.61 TP53 PGR ESR1
4 DNA-binding transcription factor activity GO:0003700 9.54 TP53 PGR ESR1
5 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.43 TP53 PGR ESR1
6 ATPase binding GO:0051117 9.4 PGR ESR1
7 nuclear receptor activity GO:0004879 9.32 PGR ESR1
8 steroid binding GO:0005496 9.16 PGR ESR1
9 enzyme binding GO:0019899 9.13 TP53 PGR ESR1
10 steroid hormone receptor activity GO:0003707 8.62 PGR ESR1

Sources for Vestibular Gland Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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