MCID: VST001
MIFTS: 36

Vestibular Neuronitis

Categories: Ear diseases, Neuronal diseases

Aliases & Classifications for Vestibular Neuronitis

Summaries for Vestibular Neuronitis

Disease Ontology : 12 A inner ear infectious disease caused by a viral infection which involves inflammation of the vestibular nerve. It usually results as a complication of an upper respiratory infection. This causes sudden and severe vertigo, nausea and vomiting. Auditory symptoms are usually absent.

MalaCards based summary : Vestibular Neuronitis, also known as epidemic neurolabyrinthitis, is related to labyrinthitis and viral labyrinthitis. An important gene associated with Vestibular Neuronitis is RTEL1 (Regulator Of Telomere Elongation Helicase 1). The drugs Prednisolone and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include eye and testes, and related phenotypes are Synthetic lethal with vaccinia virus (VACV) infection and embryo

Wikipedia : 76 Labyrinthitis, also known as vestibular neuritis, is the inflammation of the inner ear. It results in a... more...

Related Diseases for Vestibular Neuronitis

Graphical network of the top 20 diseases related to Vestibular Neuronitis:



Diseases related to Vestibular Neuronitis

Symptoms & Phenotypes for Vestibular Neuronitis

GenomeRNAi Phenotypes related to Vestibular Neuronitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with vaccinia virus (VACV) infection GR00362-A 8.8 CACNA1A PIR SALL1

MGI Mouse Phenotypes related to Vestibular Neuronitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 9.55 LMX1A PIR RTEL1 SALL1 TCOF1
2 growth/size/body region MP:0005378 9.43 CACNA1A LMX1A PIR RTEL1 SALL1 TCOF1
3 nervous system MP:0003631 9.02 CACNA1A LMX1A RTEL1 SALL1 TCOF1

Drugs & Therapeutics for Vestibular Neuronitis

Drugs for Vestibular Neuronitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 38)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
3
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3 302-25-0
4
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3 2921-57-5
5
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
6
Prednisolone hemisuccinate Experimental Phase 4,Phase 3 2920-86-7
7 Hormone Antagonists Phase 4,Phase 3,Phase 2
8 Antiemetics Phase 4,Phase 3
9 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
10 Neuroprotective Agents Phase 4,Phase 3
11 Prednisolone acetate Phase 4,Phase 3
12 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
13 Hormones Phase 4,Phase 3,Phase 2
14 glucocorticoids Phase 4,Phase 3,Phase 2
15 Autonomic Agents Phase 4,Phase 3
16 Gastrointestinal Agents Phase 4,Phase 3
17 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
18 Peripheral Nervous System Agents Phase 4,Phase 3
19 Protective Agents Phase 4,Phase 3
20 Methylprednisolone acetate Phase 4,Phase 3
21 Betamethasone Valerate Phase 4 2152-44-5
22 Anti-Asthmatic Agents Phase 4,Phase 3
23 Betamethasone benzoate Phase 4
24 Betamethasone sodium phosphate Phase 4
25 Respiratory System Agents Phase 4,Phase 3
26 Betamethasone-17,21-dipropionate Phase 4
27
Cilostazol Approved, Investigational Phase 3 73963-72-1 2754
28 Ginkgo Phase 3
29 Bronchodilator Agents Phase 3
30 Phosphodiesterase Inhibitors Phase 3
31 Vasodilator Agents Phase 3
32 Platelet Aggregation Inhibitors Phase 3
33 Phosphodiesterase 3 Inhibitors Phase 3
34 Fibrinolytic Agents Phase 3
35
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
36
Dexamethasone Approved, Investigational, Vet_approved Early Phase 1 50-02-2 5743
37
Dexamethasone acetate Approved, Investigational, Vet_approved Early Phase 1 1177-87-3
38 BB 1101 Early Phase 1

Interventional clinical trials:

(show all 19)
# Name Status NCT ID Phase Drugs
1 Acute Unilateral Vestibulopathy and Corticosteroid Treatment Recruiting NCT02912182 Phase 4 Betamethasone;Placebo;Prednisolone
2 The Efficacy of Steroid Therapy in Vestibular Neuritis Completed NCT02098330 Phase 3 Ginkgo biloba & Methylprednisolone;Ginkgo biloba
3 Effect of Renexin Tablet in Patients With Recurrent Vestibulopathy Terminated NCT01895400 Phase 3 Renexin (cilostazol 100mg + gingko biloba extract 80 mg);Placebo
4 Prednisone Treatment for Vestibular Neuronitis Completed NCT00271791 Phase 2 Prednisone;Prednisone
5 Complementary/Alternative Medicine for Abnormality in the Vestibular (Balance) System Completed NCT00032383 Phase 1, Phase 2
6 The Role of Corticosteroids and Vestibular Exercises in Recovery of Vestibular Neuritis Unknown status NCT01231009 Early Phase 1 Corticosteroids
7 Characterisation of Cortical Vestibular Evoked Potentials (C-VEPs) Unknown status NCT02463695 Not Applicable
8 Vestibular System in Migrainous Vertigo Patients Unknown status NCT00901953
9 Game Based Vestibular Exercise for Home Rehabilitation Unknown status NCT02134444 Not Applicable
10 Recovery of Visual Acuity in People With Vestibular Deficits Completed NCT00411216 Not Applicable
11 Home-based Computer Gaming in Vestibular Rehabilitation Completed NCT01943955 Not Applicable
12 Clinical Evaluation of a Novel Balance, Vestibular and Oculomotor Assessment Tool Completed NCT02171312
13 Spatial Orientation and Vestibular Function Completed NCT02212847 Not Applicable
14 To Study the Characteristics of Different Types of Vertigo in Patients Attending the Ear Nose & Throat (ENT) Clinics. Completed NCT02213120
15 MRIPositive Diagnosis of Vestibular Neuritis Using Fluid Attenuated Inversion Recuperation (FLAIR) Sequence on a 1.5 Tesla Recruiting NCT03452410
16 Assessment and Treatment of Patients With Long-term Dizziness in Primary Care Recruiting NCT02655575 Not Applicable
17 Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT) Recruiting NCT02483429 Not Applicable
18 Simultaneous Recordings of Cervical and Ocular Vestibular-evoked Myogenic Potentials Enrolling by invitation NCT03049683
19 Vestibulopathy With Vestibulo Ocular Reflex (VOR) Gain Deficit Not yet recruiting NCT03271775 Not Applicable

Search NIH Clinical Center for Vestibular Neuronitis

Cochrane evidence based reviews: vestibular neuronitis

Genetic Tests for Vestibular Neuronitis

Anatomical Context for Vestibular Neuronitis

MalaCards organs/tissues related to Vestibular Neuronitis:

41
Eye, Testes

Publications for Vestibular Neuronitis

Articles related to Vestibular Neuronitis:

(show top 50) (show all 75)
# Title Authors Year
1
Bell's palsy and vestibular neuronitis. ( 25015516 )
2014
2
Investigation of seasonal variability of vestibular neuronitis. ( 24063368 )
2013
3
Vestibular evoked myogenic potentials in vestibular neuronitis. ( 22368986 )
2011
4
Comorbid intracranial vertebral artery asymmetry as a risk factor for severe vestibular neuronitis. ( 21317672 )
2011
5
Herpes simplex virus type 1 in saliva of patients with vestibular neuronitis: a preliminary study. ( 22045284 )
2011
6
Treatment of acute vestibular neuronitis with glucocorticoids. ( 21817947 )
2011
7
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Bet 1: steroids for patients with vestibular neuronitis. ( 19850811 )
2009
8
[Late and sudden recovery of sudden deafness or vestibular neuronitis]. ( 17692812 )
2007
9
Herpes encephalitis preceded by ipsilateral vestibular neuronitis. ( 16246566 )
2005
10
A prospective study on the course of anxiety after vestibular neuronitis. ( 15046973 )
2004
11
Vestibular neuronitis in pilots: follow-up results and implications for flight safety. ( 12567089 )
2003
12
Lipoprotein (a) and acute-phase response in patients with vestibular neuronitis. ( 14636287 )
2003
13
Vestibular neuronitis: a viral neuropathy. ( 12077899 )
2002
14
Vestibular neuronitis in children: study of medium and long term follow-up. ( 10967381 )
2000
15
Vestibular neuronitis. ( 10431900 )
1999
16
The pathology of facial and vestibular neuronitis. ( 10442771 )
1999
17
A proposal for introducing a modified vestibular index in neurotology. The classification of vestibular neuronitis. ( 8891479 )
1996
18
Comparative study on gait abnormality in patients with vestibular neuronitis and patients with large acoustic neuroma. ( 7610866 )
1995
19
Central disorders in vestibular neuronitis. ( 7610868 )
1995
20
A case with symptoms of vestibular neuronitis caused by an intramedullary lesion. ( 7642999 )
1995
21
Enhanced MRI in patients with vestibular neuronitis. ( 7610885 )
1995
22
Vestibular neuronitis in aged patients: results from an epidemiological survey by questionnaire in Japan. ( 8470501 )
1993
23
Vestibular neuronitis: epidemiological survey by questionnaire in Japan. ( 8470507 )
1993
24
Follow-up of square drawing test in vestibular neuronitis. ( 8470497 )
1993
25
A clinical observation of benign paroxysmal positional vertigo (BPPV) after vestibular neuronitis (VN). ( 8470503 )
1993
26
Vestibular neuronitis in children. ( 8470500 )
1993
27
Vestibular compensation in vestibular neuronitis: evaluation of positional nystagmus and caloric nystagmus. ( 8470494 )
1993
28
Relationship between GBST and equilibrium examination in vestibular neuronitis. ( 8470491 )
1993
29
Vestibular neuronitis. Proceedings of an international symposium on vestibular ganglia and vestibular neuronitis. Yamaguchi, Japan, 14-16 September, 1991. ( 8470473 )
1993
30
Progress of caloric response of vestibular neuronitis. ( 8470487 )
1993
31
Prolonged dysequilibrium in three cases with vestibular neuronitis: efficacy of vestibular rehabilitation. ( 8470498 )
1993
32
Vestibular compensation in vestibular neuronitis. Long-term follow-up evaluation. ( 8379299 )
1993
33
Serum viral antibody titer in vestibular neuronitis. ( 8385868 )
1993
34
Bilateral vestibular neuronitis. ( 8470502 )
1993
35
Vestibular neuronitis: a review of a common cause of vertigo in general practice. ( 8323804 )
1993
36
Neuroborreliosis in the etiology of vestibular neuronitis. ( 8470505 )
1993
37
Interpretation of the combined galvanic test. Findings from cases with vestibular neuronitis. ( 8470490 )
1993
38
Clinical observation of 32 cases of vestibular neuronitis. ( 8470478 )
1993
39
Vestibular neuronitis evaluated by the combined galvanic test. ( 8470489 )
1993
40
Recovery of the vestibular function after vestibular neuronitis. ( 8470496 )
1993
41
A clinical study of vestibular neuronitis. ( 1897712 )
1991
42
Compensatory process of vestibular neuronitis. From findings of combined galvanic test and caloric test. ( 1927436 )
1991
43
Serovirological study of vestibular neuronitis. ( 2635537 )
1989
44
Vestibular neuronitis. Pathogenesis in the view of virological study of CSF. ( 2635536 )
1989
45
Vestibular neuronitis. An otoneurological evaluation. ( 3068952 )
1988
46
Vestibular neuronitis in childhood. ( 3245418 )
1988
47
Vestibular neuronitis--serum and CSF virus antibody titer. ( 3017280 )
1986
48
Neurotologic evidence of central and peripheral involvement in patients with vestibular neuronitis. ( 3931027 )
1985
49
Vestibular neuronitis: the experience at Harare Central Hospital, Zimbabwe: case report. ( 4076038 )
1985
50
Vestibular neuronitis: neurotological findings and progress. ( 4022591 )
1985

Variations for Vestibular Neuronitis

Expression for Vestibular Neuronitis

Search GEO for disease gene expression data for Vestibular Neuronitis.

Pathways for Vestibular Neuronitis

GO Terms for Vestibular Neuronitis

Biological processes related to Vestibular Neuronitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 central nervous system neuron differentiation GO:0021953 8.62 CACNA1A LMX1A

Molecular functions related to Vestibular Neuronitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ion channel activity GO:0005216 8.62 CACNA1A SLC9C1

Sources for Vestibular Neuronitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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