MCID: VRL001
MIFTS: 25

Viral Laryngitis

Categories: Infectious diseases, Oral diseases, Respiratory diseases

Aliases & Classifications for Viral Laryngitis

MalaCards integrated aliases for Viral Laryngitis:

Name: Viral Laryngitis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3436
NCIt 49 C27305
UMLS 71 C0853195

Summaries for Viral Laryngitis

Disease Ontology : 12 A acute laryngitis which is caused by viral infection.

MalaCards based summary : Viral Laryngitis is related to herpes zoster and emphysematous cholecystitis. An important gene associated with Viral Laryngitis is DOCK11 (Dedicator Of Cytokinesis 11). The drugs Oregano and Peppermint have been mentioned in the context of this disorder. Related phenotype is integument.

Related Diseases for Viral Laryngitis

Diseases in the Laryngitis family:

Chronic Laryngitis Viral Laryngitis
Acute Laryngitis

Diseases related to Viral Laryngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 167)
# Related Disease Score Top Affiliating Genes
1 herpes zoster 29.5 TRPV1 CRP CD40LG
2 emphysematous cholecystitis 10.4 GPT CRP
3 tinea unguium 10.3 GPT CRP
4 photokeratitis 10.3 TRPV1 TRPA1
5 dentin sensitivity 10.3 TRPV1 TRPA1
6 epstein-barr virus hepatitis 10.3 GPT CD40LG
7 heterophyiasis 10.3 GPT CD40LG
8 progressive familial heart block, type ib 10.3 TRPV1 TRPA1
9 hepatic tuberculosis 10.3 GPT GGT1
10 sick building syndrome 10.3 TRPV1 TRPA1
11 non-alcoholic steatohepatitis 10.3 GPT GGT1
12 heart aneurysm 10.3 GPT CRP
13 cauda equina syndrome 10.3 PROC CRP
14 opportunistic bacterial infectious disease 10.2 CRP CABIN1
15 catastrophic antiphospholipid syndrome 10.2 PROC CD40LG
16 paralytic ileus 10.2 GPT CRP
17 nocardiosis 10.2 CRP CABIN1
18 coronary aneurysm 10.2 GPT CRP
19 subungual glomus tumor 10.2 TRPV1 CRP
20 large intestine lipoma 10.2 GPT CRP
21 orbital plasma cell granuloma 10.2 CRP CD40LG
22 chronic orbital inflammation 10.1 CRP CD40LG
23 japanese spotted fever 10.1 CRP CD40LG
24 inferolateral myocardial infarct 10.1 GGT1 CST3
25 neuroretinitis 10.1 CRP CD40LG
26 fatty liver disease, nonalcoholic 1 10.1 GPT GGT1
27 kwashiorkor 10.1 GPT CRP
28 intracranial sinus thrombosis 10.1 CRP CD40LG
29 optic papillitis 10.1 CRP CD40LG
30 late congenital syphilis 10.1 CRP CD40LG
31 tertiary syphilis 10.1 CRP CD40LG
32 epiglottitis 10.1 CRP CD40LG
33 functional gastric disease 10.1 TRPV1 GPT CRP
34 mononeuritis of upper limb and mononeuritis multiplex 10.1 CRP CD40LG
35 mononeuritis multiplex 10.1 CRP CD40LG
36 paine syndrome 10.1 TRPV1 TRPA1 CABIN1
37 aortitis 10.1 CRP CD40LG
38 subacute bacterial endocarditis 10.1 CRP CD40LG
39 cerebritis 10.1 CRP CD40LG
40 cat-scratch disease 10.1 CRP CD40LG
41 parotid disease 10.1 CRP CD40LG
42 early congenital syphilis 10.1 CRP CD40LG
43 lipoma of colon 10.1 GPT CRP
44 acute kidney failure 10.1 GPT CST3 CABIN1
45 bacterial conjunctivitis 10.1 CRP CD40LG
46 laryngitis 10.1
47 maxillary sinusitis 10.1 CRP CD40LG
48 abdominal tuberculosis 10.1 CRP CD40LG
49 malignant essential hypertension 10.0 PROC CD40LG CABIN1
50 tenosynovitis 10.0 CRP CD40LG

Graphical network of the top 20 diseases related to Viral Laryngitis:



Diseases related to Viral Laryngitis

Symptoms & Phenotypes for Viral Laryngitis

MGI Mouse Phenotypes related to Viral Laryngitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.23 ANK1 CD40LG GGT1 IGFBP7 SAR1B TRPA1

Drugs & Therapeutics for Viral Laryngitis

Drugs for Viral Laryngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Oregano Approved Phase 1, Phase 2
2
Peppermint Approved Phase 1, Phase 2
3
Rosemary Experimental Phase 1, Phase 2
4 Eucalyptus Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Some Aromatic Medical Plants. Completed NCT00611390 Phase 1, Phase 2

Search NIH Clinical Center for Viral Laryngitis

Genetic Tests for Viral Laryngitis

Anatomical Context for Viral Laryngitis

Publications for Viral Laryngitis

Articles related to Viral Laryngitis:

# Title Authors PMID Year
1
Viral laryngitis: a mimic and a monster - range, presentation, management. 61
26397458 2015
2
[Child dyspnea]. 61
26165098 2015
3
[Pseudomembranous upper respiratory tract infection caused by herpes simplex virus in an adult]. 61
12553120 2002
4
Herpes simplex viral laryngitis. 61
10855577 2000
5
[Diagnosis and therapy of hoarseness]. 61
8927909 1996
6
Hoarseness. From viral laryngitis to glottic cancer. 61
8153040 1994
7
[Herpes of the larynx. Apropos of 3 cases]. 61
8210094 1993
8
[Viral laryngitis]. 61
13816462 1960

Variations for Viral Laryngitis

Expression for Viral Laryngitis

Search GEO for disease gene expression data for Viral Laryngitis.

Pathways for Viral Laryngitis

GO Terms for Viral Laryngitis

Biological processes related to Viral Laryngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 zymogen activation GO:0031638 9.4 GGT2 GGT1
2 regulation of immune system process GO:0002682 9.37 GGT2 GGT1
3 detection of chemical stimulus involved in sensory perception of pain GO:0050968 9.32 TRPV1 TRPA1
4 thermoception GO:0050955 9.26 TRPV1 TRPA1
5 peptide modification GO:0031179 9.16 GGT2 GGT1
6 leukotriene D4 biosynthetic process GO:1901750 9.13 GGTLC3 GGT2 GGT1
7 glutathione catabolic process GO:0006751 8.8 GGTLC3 GGT2 GGT1

Molecular functions related to Viral Laryngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium-release channel activity GO:0015278 9.16 TRPV1 TRPA1
2 peptidyltransferase activity GO:0000048 8.96 GGT2 GGT1
3 glutathione hydrolase activity GO:0036374 8.8 GGTLC3 GGT2 GGT1

Sources for Viral Laryngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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