MCID: VRL005
MIFTS: 41

Viral Pneumonia

Categories: Infectious diseases, Respiratory diseases

Aliases & Classifications for Viral Pneumonia

MalaCards integrated aliases for Viral Pneumonia:

Name: Viral Pneumonia 12 15 17
Pneumonia, Viral 45 74

Classifications:



External Ids:

Disease Ontology 12 DOID:10533
ICD9CM 36 480 480.9
MeSH 45 D011024
SNOMED-CT 69 75570004
ICD10 34 J12 J12.9
UMLS 74 C0032310

Summaries for Viral Pneumonia

Disease Ontology : 12 A pneumonia described as an inflammatory illness of the lung commonly caused by viruses such as influenza virus, parainfluenza, adenovirus, rhinovirus, herpes simplex virus, respiratory syncytial virus, hantavirus, and cytomegalovirus.

MalaCards based summary : Viral Pneumonia, also known as pneumonia, viral, is related to bacterial pneumonia and bronchiolitis. An important gene associated with Viral Pneumonia is CRP (C-Reactive Protein), and among its related pathways/superpathways are Th17 cell differentiation and T cell receptor signaling pathway. The drugs Ganciclovir and Acyclovir have been mentioned in the context of this disorder. Affiliated tissues include testes, endothelial and neutrophil.

Wikipedia : 77 Viral pneumonia is a pneumonia caused by a virus. Viruses are one of the two major causes of pneumonia,... more...

Related Diseases for Viral Pneumonia

Diseases in the Pneumonia family:

Viral Pneumonia Bacterial Pneumonia

Diseases related to Viral Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 bacterial pneumonia 29.8 CRP IL17A IL6
2 bronchiolitis 29.8 CRP IL17A IL6
3 mycoplasma pneumoniae pneumonia 29.6 CRP IL17A IL6
4 bacterial infectious disease 29.6 CRP IL17A IL6
5 lung disease 29.6 IL17A IL6 NSMCE3
6 malaria 29.2 CR1 CRP IL17A IL6
7 pneumonia 11.6
8 influenza 11.5
9 lung disease, immunodeficiency, and chromosome breakage syndrome 11.1
10 viral infectious disease 10.4
11 cold agglutinin disease 10.3 CRP IL6
12 cryopyrin-associated periodic syndrome 10.3 CRP IL6
13 acute cholangitis 10.3 CRP IL6
14 uremic pruritus 10.3 CRP IL6
15 neutrophilia, hereditary 10.3 CRP IL6
16 spinal disease 10.3 CRP IL6
17 multicentric castleman disease 10.3 CRP IL6
18 relapsing polychondritis 10.3 CRP IL6
19 subacute thyroiditis 10.3 CRP IL6
20 intussusception 10.3 CRP IL6
21 louse-borne relapsing fever 10.3 CRP IL6
22 cecal disease 10.3 CRP IL6
23 pyelitis 10.3 CRP IL6
24 ischemic heart disease 10.3 CRP IL6
25 mesenteric lymphadenitis 10.3 CRP IL6
26 viral meningitis 10.3 CRP IL6
27 hypersensitivity reaction type iii disease 10.3 CRP IL6
28 intermittent explosive disorder 10.3 CRP IL6
29 intermediate coronary syndrome 10.3 CRP IL6
30 systolic heart failure 10.3 CRP IL6
31 prediabetes syndrome 10.3 CRP IL6
32 acute cystitis 10.3 CRP IL6
33 acute pyelonephritis 10.3 CRP IL6
34 pyelonephritis 10.3 CRP IL6
35 apnea, obstructive sleep 10.3 CRP IL6
36 adult-onset still's disease 10.3 CRP IL6
37 polyarteritis nodosa 10.3 CRP IL6
38 angina pectoris 10.3 CRP IL6
39 perinatal necrotizing enterocolitis 10.3 CRP IL6
40 exanthem 10.3 CRP IL6
41 infective endocarditis 10.3 CRP IL6
42 endocarditis 10.3 CRP IL6
43 lymph node disease 10.3 CRP IL6
44 hemorrhagic fever with renal syndrome 10.3 CRP IL6
45 intermittent claudication 10.3 CRP IL6
46 collagen disease 10.3 CRP IL6
47 peripheral artery disease 10.3 CRP IL6
48 pericardial effusion 10.3 CRP IL6
49 sleep disorder 10.3 CRP IL6
50 leptospirosis 10.3 CRP IL6

Comorbidity relations with Viral Pneumonia via Phenotypic Disease Network (PDN):


Acute Cystitis Bronchitis
Chronic Myocardial Ischemia Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Hypothyroidism Ischemic Heart Disease
Postinflammatory Pulmonary Fibrosis Respiratory Failure

Graphical network of the top 20 diseases related to Viral Pneumonia:



Diseases related to Viral Pneumonia

Symptoms & Phenotypes for Viral Pneumonia

Drugs & Therapeutics for Viral Pneumonia

Drugs for Viral Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 36)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ganciclovir Approved, Investigational Phase 4 82410-32-0 3454
2
Acyclovir Approved Phase 4 59277-89-3 2022
3
Oseltamivir Approved Phase 4 204255-11-8, 196618-13-0 65028
4 Anti-Infective Agents Phase 4,Phase 3,Not Applicable
5 Antiviral Agents Phase 4,Phase 3
6 Nucleic Acid Synthesis Inhibitors Phase 4
7 Ganciclovir triphosphate Phase 4
8 Antibiotics, Antitubercular Phase 4
9 Antitubercular Agents Phase 4
10 Anti-Bacterial Agents Phase 4,Not Applicable
11
Fluticasone Approved, Experimental Phase 3 90566-53-3 62924
12
Hydrocortisone Approved, Vet_approved Phase 3 50-23-7 5754
13
Hydrocortisone acetate Approved, Vet_approved Phase 3 50-03-3
14 Dermatologic Agents Phase 3
15 Respiratory System Agents Phase 3
16 Peripheral Nervous System Agents Phase 3
17 Anti-Allergic Agents Phase 3
18 Bronchodilator Agents Phase 3
19 Anti-Inflammatory Agents Phase 3
20 Anti-Asthmatic Agents Phase 3
21 Autonomic Agents Phase 3
22 Hydrocortisone-17-butyrate Phase 3
23 Hydrocortisone hemisuccinate Phase 3
24 Hydrocortisone 17-butyrate 21-propionate Phase 3
25
Erythromycin Approved, Investigational, Vet_approved Not Applicable 114-07-8 441411 12560
26
Azithromycin Approved Not Applicable 83905-01-5 447043 55185
27
Nitric Oxide Approved 10102-43-9 145068
28
Ceftriaxone Approved 73384-59-5 5479530 5361919
29
Levofloxacin Approved, Investigational 100986-85-4 149096
30
Spiramycin Approved 24916-50-5
31
Ofloxacin Approved 82419-36-1 4583
32 Gastrointestinal Agents Not Applicable
33 Erythromycin Ethylsuccinate Not Applicable
34 Erythromycin stearate Not Applicable
35 Erythromycin Estolate Not Applicable
36 Cephalosporins Not Applicable

Interventional clinical trials:

(show all 21)
# Name Status NCT ID Phase Drugs
1 PTH - Preemptive Treatment for Herpesviridae Unknown status NCT02152358 Phase 4 Aciclovir;Ganciclovir;Placebo
2 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
3 Rapid Empiric Treatment With Oseltamivir Study (RETOS) Completed NCT01248715 Phase 4 oseltamivir
4 Inhaled Corticosteroids in U-5 Children With Acute Respiratory Infection in Uganda: A Randomised Trial Completed NCT01868113 Phase 3 Inhaled corticosteroid
5 A Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Non-Hospitalized Participants With Influenza A Infection Who Are at Risk of Developing Complications Recruiting NCT03381196 Phase 3 Pimodivir 600 mg;Placebo
6 A Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Hospitalized Participants With Influenza A Infection Recruiting NCT03376321 Phase 3 Pimodivir 600 mg;Placebo
7 Low Doses Corticosteroids as Adjuvant Therapy for the Treatment of Severe H1N1 Flu Terminated NCT01014364 Phase 3 hydrocortisone;isotonic saline
8 Inhaled GM-CSF for Respiratory Virus-Associated Severe Pneumonia Withdrawn NCT02601365 Phase 1 Sargramostim 0.04 mcg/kg/dose;Sargramostim 0.2mcg/kg/dose;Sargramostim 1 mcg/kg/dose
9 A Registry Study on Xiyanping(a Chinese Medicine Injection) Used in Fifty Hospitals Unknown status NCT01612572
10 The Impact of Simultaneous Presence of Viral and Bacterial Pathogens on Therapy and Course of Severe Pneumonia Unknown status NCT02203110
11 Effectiveness Study of Integrative Treatment for Pediatric Community Acquired Pneumonia Unknown status NCT02362906 Not Applicable Xiyanping injection;wind-heat formula granules;phlegm-heat formula granules;Fu-xiong San;second generation cephalosporin;Erythromycin;Azithromycin
12 Surveillance of Hospitalised Pneumonia and Bacterial Meningitis in Tône District, Togo, 2010-2013 Unknown status NCT01747369
13 Severe Pandemic H1N1 Infection in ICU: Comparative Resource Utilization Completed NCT01485237
14 Serum and Bronchoalveolar Inflammatory Parameters in Patients With Severe Adult Respiratory Distress Syndrome Completed NCT03641690
15 Pneumonia in the Intensive Care Unit (ICU) Setting Completed NCT02685930
16 Long-term Outcome and Lung Capacity in Survivors of ARDS Due to Influenza A (H1N1) v2009 The RESPIFLU Study Completed NCT01271842
17 Procalcitonin Test for Differentiation of the Cause of Pneumonia Active, not recruiting NCT03350802
18 Managing Bacterial Pneumonia in Children Without Antimicrobials Not yet recruiting NCT03256474
19 Use of TREM-1 Protein to Differentiate Viral and Bacterial Pneumonias in Intubated Children Withdrawn NCT00645619
20 Clinical Pediatric Pneumonia Score in Critically Ill Children Withdrawn NCT02139384
21 Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For CAP Withdrawn NCT01662258 Not Applicable

Search NIH Clinical Center for Viral Pneumonia

Cochrane evidence based reviews: pneumonia, viral

Genetic Tests for Viral Pneumonia

Anatomical Context for Viral Pneumonia

MalaCards organs/tissues related to Viral Pneumonia:

42
Testes, Endothelial, Neutrophil, Kidney, Monocytes, Lymph Node, Eye

Publications for Viral Pneumonia

Articles related to Viral Pneumonia:

(show top 50) (show all 167)
# Title Authors Year
1
High mortality from viral pneumonia in patients with cancer. ( 31081422 )
2019
2
Viral pneumonia: which patients should we focus on? ( 31081438 )
2019
3
Application of metabolomics in viral pneumonia treatment with traditional Chinese medicine. ( 30911327 )
2019
4
Does atopy affect the course of viral pneumonia? ( 28634031 )
2018
5
The Impact of Pneumococcal Vaccination on Bacterial and Viral Pneumonia in Western Australian Children: Record Linkage Cohort Study of 469589 Births, 1996-2012. ( 29069315 )
2018
6
Stewardship opportunities in viral pneumonia: Why not the immunocompromised? ( 29423923 )
2018
7
Radiographic and CT Features of Viral Pneumonia. ( 29757717 )
2018
8
Viral pneumonia: etiologies and treatment. ( 29680828 )
2018
9
Impact of angiotensin-converting enzyme inhibitors and statins on viral pneumonia. ( 30948970 )
2018
10
Influenza and Viral Pneumonia. ( 30390743 )
2018
11
Hemorrhagic encephalitis associated with H3N2 influenza A viral pneumonia. ( 29440541 )
2018
12
YKL-40 levels are associated with disease severity and prognosis of viral pneumonia, but not available in bacterial pneumonia in children. ( 30514252 )
2018
13
Application of extracorporeal membrane oxygenation in patients with severe acute respiratory distress syndrome induced by avian influenza A (H7N9) viral pneumonia: national data from the Chinese multicentre collaboration. ( 29310581 )
2018
14
Bacterial and viral pneumonia: New insights from the Drakenstein Child Health Study. ( 28687247 )
2017
15
Severe viral pneumonia in adults: what is important for the ICU physician? ( 28633583 )
2017
16
Viral Pneumonia in Patients with Hematopoietic Cell Transplantation and Hematologic Malignancies. ( 28477640 )
2017
17
Effect of low-to-moderate-dose corticosteroids on mortality of hospitalized adolescents and adults with influenza A(H1N1)pdm09 viral pneumonia. ( 28464462 )
2017
18
Retrospective review of epidemic viral pneumonia cases in Turkey: A multicenter study. ( 28413489 )
2017
19
Vaccines in the Prevention of Viral Pneumonia. ( 28159157 )
2017
20
Epidemiology of Viral Pneumonia. ( 28159152 )
2017
21
Secondary organizing pneumonia following viral pneumonia caused by severe influenza B: a case report and literature reviews. ( 28810835 )
2017
22
Emodin Inhibition of Influenza A Virus Replication and Influenza Viral Pneumonia via the Nrf2, TLR4, p38/JNK and NF-kappaB Pathways. ( 29057806 )
2017
23
Viral Pneumonia in Patients with Hematologic Malignancy or Hematopoietic Stem Cell Transplantation. ( 28159165 )
2017
24
Viral Pneumonia and Acute Respiratory Distress Syndrome. ( 28159154 )
2017
25
Protective effects of Yinhuapinggan granule on mice with influenza viral pneumonia. ( 26655878 )
2016
26
Graft Loss and CLAD-Onset Is Hastened by Viral Pneumonia After Lung Transplantation. ( 27467538 )
2016
27
Adjuvant Corticosteroid Treatment in Adults With Influenza A (H7N9) Viral Pneumonia. ( 26934144 )
2016
28
Review of Non-Bacterial Infections in Respiratory Medicine: Viral Pneumonia. ( 25957460 )
2015
29
Impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: an opportunity for stewardship. ( 26577540 )
2015
30
The Serum Value of NO and IL-17 were Increased in Children with Influenza A Viral Pneumonia. ( 26642702 )
2015
31
CAUSATIVE AGENTS OF SEVERE COMMUNITY ACQUIRED VIRAL PNEUMONIA AMONG CHILDREN IN EASTERN THAILAND. ( 26867384 )
2015
32
Epidemiology, Co-Infections, and Outcomes of Viral Pneumonia in Adults: An Observational Cohort Study. ( 26683973 )
2015
33
IgA level in plasma as a differential factor for influenza infection in severe viral pneumonia. ( 24380719 )
2014
34
Epidemiology, etiology, x-ray features, importance of co-infections and clinical features of viral pneumonia in developing countries. ( 24410617 )
2014
35
Combination therapy with hepatocyte growth factor and oseltamivir confers enhanced protection against influenza viral pneumonia. ( 24894172 )
2014
36
Middle East respiratory syndrome (MERS): a new zoonotic viral pneumonia. ( 25089913 )
2014
37
Aging exacerbates damage and delays repair of alveolar epithelia following influenza viral pneumonia. ( 25265939 )
2014
38
Predictors of viral pneumonia in patients with community-acquired pneumonia. ( 25531901 )
2014
39
Viral pneumonia in severe respiratory failure. ( 24602995 )
2014
40
Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia. ( 23344833 )
2013
41
Gravity-dependent opacity in pure influenza viral pneumonia. ( 23370759 )
2013
42
Predictors of viral pneumonia: the need for viral testing in all patients hospitalized for nursing home-acquired pneumonia. ( 23441872 )
2013
43
Are statins beneficial for viral pneumonia? ( 23633609 )
2013
44
Effect of the Haoqinqingdan decoction on damp-heat syndrome in rats with influenza viral pneumonia. ( 23790339 )
2013
45
Influenza and endemic viral pneumonia. ( 24094391 )
2013
46
A patient who survived primary seasonal influenza viral pneumonia: histologic findings obtained via bronchoscopy. ( 24334588 )
2013
47
H7N9 viral pneumonia: asymmetric and irregular changes on computed tomography. ( 24342341 )
2013
48
Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque. ( 22491448 )
2012
49
Radiological findings in 210 paediatric patients with viral pneumonia: a retrospective case study. ( 22514104 )
2012
50
Alveolar epithelial cells orchestrate DC function in murine viral pneumonia. ( 22996662 )
2012

Variations for Viral Pneumonia

Expression for Viral Pneumonia

Search GEO for disease gene expression data for Viral Pneumonia.

Pathways for Viral Pneumonia

GO Terms for Viral Pneumonia

Cellular components related to Viral Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromosome, telomeric region GO:0000781 8.96 NSMCE3 SMC5
2 Smc5-Smc6 complex GO:0030915 8.62 NSMCE3 SMC5

Biological processes related to Viral Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 8.96 CRP IL6
2 negative regulation of lipid storage GO:0010888 8.62 CRP IL6

Sources for Viral Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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