MCID: VSL003
MIFTS: 33

Visual Agnosia

Categories: Eye diseases, Mental diseases

Aliases & Classifications for Visual Agnosia

MalaCards integrated aliases for Visual Agnosia:

Name: Visual Agnosia 12 15
Primary Visual Agnosia 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:0060155
MeSH 44 C531604
UMLS 70 C2930796

Summaries for Visual Agnosia

Disease Ontology : 12 An agnosia that is a loss of the ability to visually recognize objects.

MalaCards based summary : Visual Agnosia, also known as primary visual agnosia, is related to apperceptive agnosia and dysgraphia. An important gene associated with Visual Agnosia is PSEN2 (Presenilin 2), and among its related pathways/superpathways are Neuroscience and Alzheimers Disease. Affiliated tissues include cortex, temporal lobe and brain, and related phenotypes are renal/urinary system and vision/eye

Wikipedia : 73 Visual agnosia is an impairment in recognition of visually presented objects. It is not due to a deficit... more...

Related Diseases for Visual Agnosia

Diseases related to Visual Agnosia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 apperceptive agnosia 30.8 PSEN2 GRN
2 dysgraphia 30.8 MAPT GRN
3 associative agnosia 30.7 MAPT GRN
4 prosopagnosia 30.6 PSEN2 MAPT HNMT GRN
5 posterior cortical atrophy 30.5 MAPT APOE
6 finger agnosia 30.4 PCAT2 MAPT
7 alexia 30.2 PSEN2 PCAT2 MAPT GRN APOE
8 agraphia 30.2 PCAT2 MAPT GRN APOE
9 amnestic disorder 30.1 PSEN1 MAPT APOE
10 apraxia 30.1 PSEN1 MAPT GRN APOE
11 aphasia 29.9 PSEN2 PSEN1 MAPT GRN APOE
12 akinetopsia 29.9 PHC1 HNMT
13 brain injury 29.9 MAPT APOE
14 simultanagnosia 29.5 PSEN2 PSEN1 PCAT2 MAPT APOE
15 ideomotor apraxia 29.5 PSEN2 MAPT GRN APOE
16 semantic dementia 29.5 PSEN1 MAPT GRN APOE
17 movement disease 29.4 PSEN1 MAPT GRN APOE
18 dementia 29.2 PSEN2 PSEN1 MAPT GRN APOE
19 speech and communication disorders 29.2 PSEN2 PSEN1 MAPT GRN APOE
20 nominal aphasia 29.2 PSEN1 PCAT2 MAPT GRN APOE
21 gerstmann syndrome 29.2 PSEN2 PSEN1 PCAT2 MAPT GRN APOE
22 agnosia 11.6
23 kluver-bucy syndrome 11.2
24 spastic paraplegia 14 11.0
25 yemenite deaf-blind hypopigmentation syndrome 10.2
26 head injury 10.2
27 frontotemporal lobar degeneration with tdp43 inclusions, grn-related 10.1 MAPT GRN
28 alzheimer disease 9 10.1 PSEN1 MAPT
29 cerebral amyloid angiopathy, itm2b-related, 1 10.1 PSEN2 PSEN1
30 writing disorder 10.1 MAPT GRN
31 anosognosia 10.1 PSEN1 APOE
32 frontotemporal dementia and/or amyotrophic lateral sclerosis 7 10.1 MAPT GRN
33 subjective cognitive decline 10.1 MAPT APOE
34 alzheimer disease 10 10.1 MAPT APOE
35 echolalia 10.1 MAPT GRN
36 binswanger's disease 10.1 MAPT APOE
37 ataxia and polyneuropathy, adult-onset 10.1
38 achromatopsia 10.1
39 vascular disease 10.1
40 age-related hearing loss 10.1 MAPT APOE
41 gerstmann-straussler disease 10.0 PSEN2 PSEN1 MAPT
42 mutism 10.0 MAPT GRN
43 mild cognitive impairment 10.0 MAPT APOE
44 autotopagnosia 10.0 PHC1 HNMT
45 alzheimer disease 7 10.0 MAPT APOE
46 arteriolosclerosis 10.0 MAPT APOE
47 progressive non-fluent aphasia 10.0 PSEN1 MAPT GRN
48 perry syndrome 10.0 MAPT GRN
49 cerebral amyloid angiopathy, app-related 10.0 PSEN2 PSEN1 APOE
50 alzheimer disease 4 10.0 PSEN2 PSEN1 APOE

Graphical network of the top 20 diseases related to Visual Agnosia:



Diseases related to Visual Agnosia

Symptoms & Phenotypes for Visual Agnosia

MGI Mouse Phenotypes related to Visual Agnosia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.35 APOE GRN MAPT PSEN1 PSEN2
2 vision/eye MP:0005391 9.1 APOE GRN MAPT PHC1 PSEN1 PSEN2

Drugs & Therapeutics for Visual Agnosia

Search Clinical Trials , NIH Clinical Center for Visual Agnosia

Cochrane evidence based reviews: primary visual agnosia

Genetic Tests for Visual Agnosia

Anatomical Context for Visual Agnosia

MalaCards organs/tissues related to Visual Agnosia:

40
Cortex, Temporal Lobe, Brain, Eye, Amygdala, Occipital Lobe, Bone Marrow

Publications for Visual Agnosia

Articles related to Visual Agnosia:

(show top 50) (show all 404)
# Title Authors PMID Year
1
Complementary deficits in perceptual classification in pure alexia and acquired prosopagnosia - New insights from two classic cases. 61
33676958 2021
2
Cerebral trauma-induced dyschromatopsia in the left hemifield: case presentation. 61
33504343 2021
3
Asymmetric Bálint's syndrome with multimodal agnosia, bilateral agraphesthesia, and ineffective kinesthetic reading due to subcortical hemorrhage in the left parieto-occipito-temporal area. 61
33103577 2020
4
Left Parietal Tumors Presenting with Smartphone Icon Visual Agnosia: Two Cases of a Modern Presentation of Gerstmann Syndrome. 61
32673807 2020
5
Sexual Behavioral Disinhibition Associated with Nucleus Lentiformis Lesion: A Forensic Neuroscience Perspective Through a Case. 61
32525581 2020
6
Altered large-scale organization of shape processing in visual agnosia. 61
32574843 2020
7
Difficulty differentiating a case of posterior cortical atrophy from a psychogenic disturbance of vision. 61
30997705 2020
8
The neuropsychological rehabilitation of visual agnosia and Balint's syndrome. 61
29366371 2019
9
Real-world size coding of solid objects, but not 2-D or 3-D images, in visual agnosia patients with bilateral ventral lesions. 61
30987739 2019
10
Role of Population Receptive Field Size in Complex Visual Dysfunctions: A Posterior Cortical Atrophy Model. 61
31403655 2019
11
Atypical non-progressive semantic impairment following allogeneic bone marrow transplantation in a patient with Waldenström's macroglobulinemia: A case report. 61
30468103 2019
12
Klüver-Bucy Syndrome Following Traumatic Brain Injury: A Systematic Synthesis and Review of Pharmacological Treatment From Cases in Adolescents and Adults. 61
30376788 2019
13
Differentiation of Types of Visual Agnosia Using EEG. 61
31735907 2018
14
Visual crowding in pure alexia and acquired prosopagnosia. 61
29902952 2018
15
The contribution of facial dynamics to subtle expression recognition in typical viewers and developmental visual agnosia. 61
29723598 2018
16
Pure optic ataxia and visual hemiagnosia - extending the dual visual hypothesis. 61
28258660 2018
17
Pediatric Klüver-Bucy Syndrome: Report of Two Cases and Review of the Literature. 61
29237192 2018
18
Optic ataxia: beyond the dorsal stream cliché. 61
29519460 2018
19
The Klüver-Bucy Syndrome. 61
29145186 2018
20
Minor Hemisphere Major Syndromes. 61
29145178 2018
21
Functional Anatomy of the Inferior Longitudinal Fasciculus: From Historical Reports to Current Hypotheses. 61
30283306 2018
22
Perceptual integration and attention in human extrastriate cortex. 61
29093537 2017
23
A novel PSEN1 (S230N) mutation causing early-onset Alzheimer's Disease associated with prosopagnosia, hoarding, and Parkinsonism. 61
28764909 2017
24
Visual agnosia and focal brain injury. 61
28843416 2017
25
Rise and fall of the two visual systems theory. 61
28545844 2017
26
Agnosic vision is like peripheral vision, which is limited by crowding. 61
28284488 2017
27
[Brodmann Areas 17, 18, and 19 in the Human Brain: An Overview]. 61
28424394 2017
28
Visual Dysfunction in Posterior Cortical Atrophy. 61
28861031 2017
29
Clinical manifestations and morphological changes in one case with post-stroke Klüver-Bucy syndrome. 61
28730259 2017
30
Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). 61
27777020 2016
31
Pearls & Oy-sters: Visual agnosia: An overlooked cortical sign. 61
27821572 2016
32
Visual attention in posterior stroke and relations to alexia. 61
26970141 2016
33
Mesiotemporal Disconnection and Hypoactivity in Klüver-Bucy Syndrome: Case Series and Literature Review. 61
27380585 2016
34
Dissociation of the Reach and the Grasp in the destriate (V1) monkey Helen: a new anatomy for the dual visuomotor channel theory of reaching. 61
27056084 2016
35
Partial Kluver-Bucy syndrome secondary to tubercular meningitis. 61
27530874 2016
36
Can patients without early, prominent visual deficits still be diagnosed of posterior cortical atrophy? 61
27423559 2016
37
Visual agnosia. 61
26358494 2016
38
The contribution of single case studies to the neuroscience of vision. 61
27061638 2016
39
[Higher Brain Dysfunction in Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS)]. 61
26873235 2016
40
Prosopagnosia: current perspectives. 61
28539812 2016
41
[Visual Texture Agnosia in Humans]. 61
26062585 2015
42
Posterior cortical atrophy as an extreme phenotype of GRN mutations. 61
25546130 2015
43
Cognitive problems related to vertebrobasilar circulation. 61
26738337 2015
44
Visual form-processing deficits: a global clinical classification. 61
22652145 2014
45
When apperceptive agnosia is explained by a deficit of primary visual processing. 61
24607265 2014
46
Randomized controlled trials in frontotemporal dementia: cognitive and behavioral outcomes. 61
24921043 2014
47
[Mind and brain "Kasane-egaki (Oomori, S.)"]. 61
24864566 2014
48
Posterior cortical atrophy--a prototypical case of dementia beginning with visual symptoms: case report. 61
24232949 2013
49
Klüver-Bucy syndrome after unilateral frontotemporal resection in a child with tuberous sclerosis. 61
23636147 2013
50
Is the right anterior temporal variant of prosopagnosia a form of 'associative prosopagnosia' or a form of 'multimodal person recognition disorder'? 61
23579426 2013

Variations for Visual Agnosia

Expression for Visual Agnosia

Search GEO for disease gene expression data for Visual Agnosia.

Pathways for Visual Agnosia

Pathways related to Visual Agnosia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.09 PSEN2 PSEN1 MAPT APOE
2 11.43 PSEN2 PSEN1 MAPT APOE
3 10.88 PSEN2 PSEN1
4 10.8 PSEN2 PSEN1
5 10.68 PSEN2 PSEN1
6 10.58 PSEN2 PSEN1 MAPT APOE
7 9.85 PSEN2 PSEN1

GO Terms for Visual Agnosia

Cellular components related to Visual Agnosia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 centrosome GO:0005813 9.62 SLF1 PSEN2 PSEN1 HNMT
2 membrane raft GO:0045121 9.58 PSEN2 PSEN1 MAPT
3 neuronal cell body GO:0043025 9.46 PSEN2 PSEN1 MAPT APOE
4 growth cone GO:0030426 9.43 PSEN2 PSEN1 MAPT
5 dendritic shaft GO:0043198 9.37 PSEN2 PSEN1
6 ciliary rootlet GO:0035253 8.96 PSEN2 PSEN1
7 gamma-secretase complex GO:0070765 8.62 PSEN2 PSEN1

Biological processes related to Visual Agnosia according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.76 PSEN1 MAPT APOE
2 negative regulation of neuron apoptotic process GO:0043524 9.7 PSEN1 GRN APOE
3 regulation of synaptic plasticity GO:0048167 9.6 PSEN1 MAPT
4 positive regulation of protein complex assembly GO:0031334 9.59 SLF2 SLF1
5 gene expression GO:0010467 9.58 PSEN1 APOE
6 positive regulation of catalytic activity GO:0043085 9.57 PSEN2 PSEN1
7 positive regulation of dendritic spine development GO:0060999 9.56 PSEN1 APOE
8 membrane protein ectodomain proteolysis GO:0006509 9.55 PSEN2 PSEN1
9 membrane protein intracellular domain proteolysis GO:0031293 9.54 PSEN2 PSEN1
10 astrocyte activation GO:0048143 9.51 PSEN1 MAPT
11 positive regulation of double-strand break repair GO:2000781 9.49 SLF2 SLF1
12 amyloid-beta metabolic process GO:0050435 9.48 PSEN2 PSEN1
13 amyloid precursor protein catabolic process GO:0042987 9.46 PSEN2 PSEN1
14 amyloid precursor protein metabolic process GO:0042982 9.43 PSEN1 APOE
15 amyloid-beta formation GO:0034205 9.4 PSEN2 PSEN1
16 Notch receptor processing GO:0007220 9.37 PSEN2 PSEN1
17 Notch receptor processing, ligand-dependent GO:0035333 9.32 PSEN2 PSEN1
18 protein localization to site of double-strand break GO:1990166 9.26 SLF2 SLF1
19 positive regulation of maintenance of mitotic sister chromatid cohesion GO:0034184 9.16 SLF2 SLF1
20 positive regulation of amyloid fibril formation GO:1905908 8.96 PSEN1 APOE
21 astrocyte activation involved in immune response GO:0002265 8.62 PSEN1 GRN

Molecular functions related to Visual Agnosia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aspartic-type endopeptidase activity GO:0004190 9.16 PSEN2 PSEN1
2 lipoprotein particle binding GO:0071813 8.96 MAPT APOE
3 aspartic endopeptidase activity, intramembrane cleaving GO:0042500 8.62 PSEN2 PSEN1

Sources for Visual Agnosia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....