MCID: VSL002
MIFTS: 39

Visual Epilepsy

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Visual Epilepsy

MalaCards integrated aliases for Visual Epilepsy:

Name: Visual Epilepsy 12 15
Epilepsy, Visual 12
Visual Seizure 71
Seizures 44

Classifications:



External Ids:

Disease Ontology 12 DOID:11832
MeSH 44 D012640
NCIt 50 C3980
SNOMED-CT 67 39194005
UMLS 71 C0270824

Summaries for Visual Epilepsy

MalaCards based summary : Visual Epilepsy, also known as epilepsy, visual, is related to early myoclonic encephalopathy and myoclonic epilepsy of lafora, and has symptoms including seizures An important gene associated with Visual Epilepsy is MFSD8 (Major Facilitator Superfamily Domain Containing 8), and among its related pathways/superpathways is Lysosome. The drugs Ethosuximide and Nitrazepam have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe, bone and brain, and related phenotypes are behavior/neurological and nervous system

Related Diseases for Visual Epilepsy

Diseases related to Visual Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 2778)
# Related Disease Score Top Affiliating Genes
1 early myoclonic encephalopathy 31.5 KCTD7 CLN8 CLN6
2 myoclonic epilepsy of lafora 31.0 CLN6 CLN3
3 ceroid lipofuscinosis, neuronal, 6 30.8 MFSD8 CLN8 CLN6 CLN5
4 tay-sachs disease 30.8 CLN6 CLN3
5 adult neuronal ceroid lipofuscinosis 30.5 PPT1 DNAJC5 CLN6
6 glycoproteinosis 30.5 CLN6 CLN3
7 aspartylglucosaminuria 30.3 CLN6 CLN5 CLN3
8 ceroid lipofuscinosis, neuronal, 4a, autosomal recessive 30.2 PPT1 DNAJC5 CLN6 CLN3
9 mucopolysaccharidosis, type iiia 30.1 DNAJC5 CLN6 CLN3
10 progressive myoclonus epilepsy 30.0 KCTD7 CLN6 CLN5 CLN3
11 progressive myoclonus epilepsy 3 29.9 PPT1 MFSD8 KCTD7 CLN8 CLN6
12 unverricht-lundborg syndrome 29.8 PPT1 MFSD8 KCTD7 CLN6 CLN5 CLN3
13 lipid storage disease 29.6 PPT1 CLN8 CLN6 CLN5 CLN3
14 mucopolysaccharidosis iii 29.5 PPT1 MFSD8 DNAJC5 CLN6 CLN5 CLN3
15 electroclinical syndrome 29.5 KCTD7 CLN6
16 ceroid lipofuscinosis, neuronal, 2 29.5 PPT1 MFSD8 DNAJC5 CLN8 CLN6 CLN5
17 ceroid lipofuscinosis, neuronal, 3 29.1 PPT1 MFSD8 KCTD7 DNAJC5 CLN8 CLN6
18 neuronal ceroid-lipofuscinoses 29.0 PPT1 MFSD8 DNAJC5 CLN8 CLN6 CLN5
19 ceroid lipofuscinosis, neuronal, 9 29.0 MFSD8 KCTD7 DNAJC5 CLN8 CLN6 CLN5
20 ceroid lipofuscinosis, neuronal, 11 29.0 PPT1 MFSD8 KCTD7 DNAJC5 CLN8 CLN6
21 ceroid lipofuscinosis, neuronal, 1 28.9 PPT1 MFSD8 KCTD7 DNAJC5 CLN8 CLN6
22 gm2 gangliosidosis 28.9 CLN6 CLN3
23 ceroid lipofuscinosis, neuronal, 7 28.9 PPT1 MFSD8 KCTD7 DNAJC5 CLN8 CLN6
24 ceroid lipofuscinosis, neuronal, 10 28.9 PPT1 MFSD8 KCTD7 DNAJC5 CLN8 CLN6
25 lysosomal storage disease 28.7 PPT1 CLN6 CLN5 CLN3
26 ceroid lipofuscinosis, neuronal, 13 28.7 PPT1 MFSD8 KCTD7 DNAJC5 CLN8 CLN6
27 ceroid lipofuscinosis, neuronal, 8, northern epilepsy variant 28.5 PPT1 MFSD8 KCTD7 ERG28 DNAJC5 CLN8
28 mucopolysaccharidosis-plus syndrome 28.4 PPT1 CLN6 CLN5 CLN3
29 epilepsy 28.3 KCTD7 CLN8 CLN6 CLN5 CLN3
30 neuronal ceroid lipofuscinosis 28.1 PPT1 MFSD8 KCTD7 ERG28 DNAJC5 CLN8
31 seizure disorder 11.9
32 malignant migrating partial seizures of infancy 11.6
33 generalized epilepsy with febrile seizures plus, type 2 11.6
34 febrile seizures 11.6
35 generalized epilepsy with febrile seizures plus, type 7 11.5
36 febrile seizures, familial, 8 11.5
37 generalized epilepsy with febrile seizures plus, type 1 11.5
38 seizures, benign familial infantile, 3 11.5
39 benign neonatal seizures 11.5
40 epilepsy, pyridoxine-dependent 11.5
41 multiple congenital anomalies-hypotonia-seizures syndrome 2 11.5
42 genetic epilepsy with febrile seizures plus 11.5
43 febrile seizures, familial, 11 11.4
44 pyridoxamine 5-prime-phosphate oxidase deficiency 11.4
45 generalized epilepsy with febrile seizures plus, type 9 11.4
46 microcephaly, seizures, and developmental delay 11.4
47 dravet syndrome 11.4
48 seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance 11.4
49 pettigrew syndrome 11.4
50 multiple congenital anomalies-hypotonia-seizures syndrome 1 11.4

Graphical network of the top 20 diseases related to Visual Epilepsy:



Diseases related to Visual Epilepsy

Symptoms & Phenotypes for Visual Epilepsy

UMLS symptoms related to Visual Epilepsy:


seizures

MGI Mouse Phenotypes related to Visual Epilepsy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.7 CLN3 CLN6 CLN8 DNAJC5 KCTD7 MFSD8
2 nervous system MP:0003631 9.5 CLN3 CLN5 CLN6 CLN8 DNAJC5 MFSD8
3 vision/eye MP:0005391 9.17 CLN3 CLN5 CLN6 CLN8 DNAJC5 MFSD8

Drugs & Therapeutics for Visual Epilepsy

Drugs for Visual Epilepsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 376)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethosuximide Approved Phase 4 77-67-8 3291
2
Nitrazepam Approved Phase 4 146-22-5 4506
3
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
4
Fosphenytoin Approved, Investigational Phase 4 93390-81-9 56339
5
Sertraline Approved Phase 4 79617-96-2 68617
6
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
7
Citalopram Approved Phase 4 59729-33-8 2771
8
Imipramine Approved Phase 4 50-49-7 3696
9
Bupropion Approved Phase 4 34911-55-2, 34841-39-9 444
10
Methohexital Approved Phase 4 151-83-7 9034
11
Norepinephrine Approved Phase 4 51-41-2 439260
12
Lithium carbonate Approved Phase 4 554-13-2
13
Nortriptyline Approved Phase 4 72-69-5 4543
14
Oxcarbazepine Approved Phase 4 28721-07-5 34312
15
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
16
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
17
Ivermectin Approved, Investigational, Vet_approved Phase 4 70288-86-7 6474909
18
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
19
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
20
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
21
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
22
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
23
Tranexamic Acid Approved Phase 4 1197-18-8 5526
24
Succinylcholine Approved Phase 4 306-40-1 5314
25
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
26
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
27
Chlordiazepoxide Approved, Illicit, Investigational Phase 4 58-25-3 2712
28
Remifentanil Approved Phase 4 132875-61-7 60815
29
Histamine Approved, Investigational Phase 4 51-45-6, 75614-87-8 774
30
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
31
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554
32
Phenobarbital Approved, Investigational Phase 4 50-06-6 4763
33
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
34
Rufinamide Approved Phase 4 106308-44-5 129228
35
Topiramate Approved Phase 4 97240-79-4 5284627
36
Valproic acid Approved, Investigational Phase 4 99-66-1 3121
37
Lamotrigine Approved, Investigational Phase 4 84057-84-1 3878
38
Phenytoin Approved, Vet_approved Phase 4 57-41-0 1775
39
Pregabalin Approved, Investigational Phase 4 148553-50-8 5486971
40
Zonisamide Approved, Investigational Phase 4 68291-97-4 5734
41
Lacosamide Approved Phase 4 860352-01-8, 175481-36-4 219078
42
Eslicarbazepine acetate Approved Phase 4 236395-14-5, 75970-99-9 123618
43
Vigabatrin Approved Phase 4 60643-86-9, 68506-86-5 5665
44
Ezogabine Approved, Investigational Phase 4 150812-12-7 121892
45
Clobazam Approved, Illicit Phase 4 22316-47-8 2789
46
Tiagabine Approved, Investigational Phase 4 115103-54-3 60648
47
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
48
Glutamic acid Approved, Nutraceutical Phase 4 56-86-0 33032
49
Inulin Approved, Investigational, Nutraceutical Phase 4 9005-80-5 24763
50
Butyric Acid Experimental, Investigational Phase 4 107-92-6 264

Interventional clinical trials:

(show top 50) (show all 868)
# Name Status NCT ID Phase Drugs
1 Prospective Open Label Evaluation of Clobazam Adjunctive Treatment of Adults With Refractory Focal Epilepsy: A Pilot Study Unknown status NCT02726919 Phase 4 Clobazam
2 A Randomised Controlled Trial of the Ketogenic Diet in the Treatment of Epilepsy in Children Under the Age of Two Years Unknown status NCT02205931 Phase 4 Antiepileptic drug therapy
3 Efficacy of Levetiracetam in Control of Neonatal Seizures Unknown status NCT03107507 Phase 4 Levetiracetam;Phenobarbital
4 Efficacy of Phenytoin in the Prophylaxis of Seizures of Patients With Pneumococcal Meningitis at Least 50 Yrs Old. A Multi-center Comparative Randomized Double-blind and Placebo-controlled Clinical Trial Unknown status NCT01478035 Phase 4 Phenytoin;placebo
5 Hyperventilation and ECT Seizure Duration: Effects on Cerebral Oxygen Saturation, and Therapeutic Outcome With Comparisons Between Etomidate and Ketamine in Patients With Major Depressive Disorder Unknown status NCT02924090 Phase 4 Etomidate;Ketamine
6 A Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Evaluation of Lamotrigine Adjunctive Therapy in Subjects Wtih Primary Generalized Tonic-Clonic Seizures Completed NCT00043901 Phase 4 lamotrigine
7 TOPAMAX� (Topiramate) Initiated as Monotherapy in Epilepsy (TIME): A Multicenter, Outpatient, Open-Label, Study to Evaluate the Dosing, Effectiveness and Safety of TOPAMAX� as Monotherapy in the Treatment of Epilepsy in Clinical Practice Completed NCT00266604 Phase 4 Topiramate
8 A Multicentre, Randomised, Active Comparator, Parallel Group Study To Compare The Effect On Cognition Of Adjunctive Therapy With Zonisamide Versus Sodium Valproate Completed NCT00713622 Phase 4 Zonisamide;Sodium valproate
9 IV Keppra in the Emergency Department for Prevention of Early Recurrent Seizures Completed NCT00510783 Phase 4 Keppra;Fosphenytoin;Dilantin
10 The Comparision of Different Doses of Sevoflurane for Induction of General Anesthesia in Electroconvulsive Therapy Completed NCT01905904 Phase 4 sevorane
11 Efficacy and Safety of Eslicarbazepine Acetate as First Add-on to Levetiracetam or Lamotrigine Monotherapy or as Later Adjunctive Treatment for Subjects With Uncontrolled Partial-onset Seizures: A Multicenter, Open-label, Non-randomized Trial Completed NCT03116828 Phase 4 Eslicarbazepine acetate;Eslicarbazepine Acetate
12 A Controlled Study of Ultrabrief Pulsewidth ECT (Electroconvulsive Therapy) Completed NCT00870805 Phase 4
13 The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled Study Completed NCT02208492 Phase 4 Levetiracetam;Carabamazepine
14 Medication Treatment Following Neuropsychologic, Dichotic and f-MRI Tests in Depressed Outpatients With Repeat f-MRI Following Treatment Completed NCT00296777 Phase 4 Escitalopram;Bupropion;Imipramine
15 Comparison Study of Efficacy and Safety of Levetiracetam Versus Valproate in Treatment of Idiopathic Generalized Tonic-clonic Seizures Completed NCT03940326 Phase 4 Levetiracetam;Valproate
16 Medication and Psychotherapy Treatment Trial for Psychogenic Nonepileptic Seizures Completed NCT00835627 Phase 4 sertraline
17 Optimization of Electroconvulsive Therapy Completed NCT00045916 Phase 4 Nortriptyline;Venlafaxine;Lithium
18 A Randomized, Double-blind, Parallel-group Multi-center Comparative Flexible-dose Trial Of Pregabalin Versus Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures. Completed NCT00537940 Phase 4 Pregabalin;Gabapentin
19 A Randomised Controlled Trial of Standard Bilateral Electroconvulsive Therapy Versus High-dose Unilateral Electroconvulsive Therapy for Severe Depression Completed NCT01907217 Phase 4 Methohexitone;Suxamethonium
20 A 24-week Prospective Open-label Multicenter Study to Evaluate the Effect on Seizure Frequency, Safety and Tolerability of Oxcarbazepine Monotherapy in Children With Partial Seizures Completed NCT00275912 Phase 4 Oxcarbazepine
21 A Multicenter, Single-arm, Open-label, Postmarketing Safety Study to Evaluate the Risk of Seizure Among Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated With Enzalutamide Who Are at Potential Increased Risk of Seizure Completed NCT01977651 Phase 4 Enzalutamide
22 A 24-Week Prospective, Open-Label, Multicenter Study to Evaluate the Effect on Seizure Frequency, Safety and Tolerability of Oxcarbazepine Monotherapy in Adult Patients With Partial Seizures Completed NCT00275925 Phase 4 Oxcarbazepine
23 Antipyretics for Preventing Recurrences of Febrile Seizures Completed NCT00568217 Phase 4 Diclofenac, Paracetamol, Ibuprofen
24 Comparison Between Melatonin and Diazepam for Prevention of Recurrent Simple Febrile Seizures: Randomized Clinical Trial Completed NCT03631901 Phase 4 oral melatonin;oral diazepam
25 A Prospective, Randomized, Open-label Clinical Trial to Assess Fever Following Simultaneous Versus Sequential Administration of PCV13, DTaP Vaccine and IIV in Young Children Completed NCT03165981 Phase 4
26 Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy: A Randomized Clinical Trial Completed NCT03052998 Phase 4 Ivermectin
27 Phase II Feasibility Study to Evaluate the Efficacy and Safety of Perampanel in Seizure Patients With Primary Glial Brain Tumors Completed NCT02363933 Phase 4 Perampanel
28 A Prospective, Randomized Study Evaluating the Efficacy and Safety of Early Diuresis Following Colorectal Surgery Completed NCT02351934 Phase 4 Furosemide;Celecoxib;Gabapentin
29 OAETREAT Extra Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy: a Completed NCT03852303 Phase 4 ivermectin
30 Gabapentin as an Adjunct to Paracervical Block for Perioperative Pain Management for Surgical Abortion: a Randomized Controlled Trial Completed NCT02944656 Phase 4 Gabapentin;Placebo
31 Pregabalin In Partial Seizures (Preps) : An Open-Label, International, Multicenter Add-On Therapy Trial Completed NCT00141427 Phase 4 Pregabalin
32 A Prospective, Open-label Study of the Structure and Function of the Retina in Adult Patients With Refractory Complex Partial Seizures Treated With Vigabatrin (Sabril®) Completed NCT01278173 Phase 4 Sabril
33 Effect of Carbamazepine and Oxcarbazepine on Serum Neuron-specific Enolase and S100B in Focal Seizures Completed NCT02705768 Phase 4 Carbamazepine;Oxcarbazepine
34 Efficacy and Safety of Intramuscular Midazolam Compared to Buccal Midazolam in Pediatric Seizures: A Randomized Controlled Trial Completed NCT02897856 Phase 4 Buccal midazolam;Intramuscular midazolam
35 An Open-label, Randomized, Multi-centre, Superiority Study to Compare, in Patients With Partial Onset Seizures, the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Added Antiepileptic Drug Completed NCT01630057 Phase 4 Adjunctive Zonisamide;Replacement with Zonisamide
36 Affective and Cognitive Consequences of ECT Completed NCT00487500 Phase 4
37 Gabapentin as an Adjunct for Pain Management During Dilation and Evacuation: A Double-blind Randomized Controlled Trial Completed NCT03635905 Phase 4 Gabapentin;Placebo
38 A Prospective, Phase 4, Open-Label, Twelve-Week Study to Examine the Cognitive Impact and Tolerability of Levetiracetam (Keppra) in Elderly Patients With Seizures of Partial Onset Completed NCT01318408 Phase 4 Levetiracetam
39 A Randomized, Open-label, Parallel Group, Multi-center, Comparative, Phase IV Trial of Levetiracetam (LEV) Versus Topiramate (TPM) as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects With Refractory Partial Onset Seizures Completed NCT01229735 Phase 4 Levetiracetam;Topiramate
40 Multicenter, Open-label Trial Evaluating the Efficacy and Safety of Perampanel Added to Monotherapy in Patients With Partial Onset Seizures With or Without Secondary Generalization Completed NCT02726074 Phase 4 Perampanel
41 PROSPECTIVE RANDOMIZED 12-WEEK CONTROLLED STUDY OF VISUAL FIELD CHANGE IN SUBJECTS WITH PARTIAL SEIZURES RECEIVING PREGABALIN OR PLACEBO Completed NCT00351611 Phase 4 Lyrica (pregabalin);placebo
42 Lyrica (Pregabalin) Administered As An Add-On Therapy For Partial Seizures (LEADER) An Open-Label, Multicenter Add-On Therapy Trial Completed NCT00288639 Phase 4 Pregabalin
43 An Open Label Study Of Zonegran (Zonisamide) In Patients With Partial Onset Seizures Completed NCT00215592 Phase 4 Zonegran
44 Treatment for Psychogenic Nonepileptic Seizures: A Pilot, 12 Week, Prospective, Randomized, Placebo-controlled, Double-blind, Clinical Trial of Sertraline in the Treatment of Comorbid Psychiatric Disorders in NES Completed NCT00159965 Phase 4 sertraline;placebo
45 Post-authorization, Observational and Prospective Follow up Study to Evaluate Effectiveness and Tolerability of Zonisamide as Adjunctive Therapy in Patients With Partial Onset Seizures Treated With Two Antiepileptic Drugs Completed NCT00659958 Phase 4 Zonisamide
46 An Open-Label, Multicenter, Multinational Study of Lacosamide as First Add-On Anti-epileptic Drug (AED) Treatment in Subjects With Partial-Onset Seizures Completed NCT00955357 Phase 4 Lacosamide
47 Assessment of Seizure Prophylaxis Protocols Using Intravenous Levetiracetam in a Neuroscience Intensive Care Unit Completed NCT00618436 Phase 4 Levetiracetam;Phenytoin
48 Prospective Trial of Intravenous Levetiracetam in Patients With Primary Brain Tumors and at Least One Symptomatic Seizure Who Undergo Biopsy or Cytoreductive Surgery (HELLO-study) Completed NCT00571155 Phase 4 levetiracetam
49 Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy: A Randomized, add-on Placebo-controlled Clinical Trial Completed NCT03590197 Phase 4 Melatonin 3 mg
50 Effect of Bupropion on Seizure Threshold in Depressed Patients Completed NCT03126682 Phase 4 Wellbutrin SR 300Mg Extended-Release Tablet

Search NIH Clinical Center for Visual Epilepsy

Cochrane evidence based reviews: seizures

Genetic Tests for Visual Epilepsy

Anatomical Context for Visual Epilepsy

MalaCards organs/tissues related to Visual Epilepsy:

40
Temporal Lobe, Bone, Brain, Prostate, Bone Marrow, Eye, Cortex

Publications for Visual Epilepsy

Articles related to Visual Epilepsy:

# Title Authors PMID Year
1
Visual seizure annotation and automated seizure detection using behind-the-ear electroencephalographic channels. 61
32160324 2020
2
Early Seizure Detection by Applying Frequency-Based Algorithm Derived from the Principal Component Analysis. 61
28860984 2017
3
Visual epilepsy in glioblastoma multiforme. 61
19803301 2008
4
Panic attacks in the differential diagnosis and treatment of resistant epilepsy. 61
12112726 2002
5
[A case of visual seizure suspected of mirror-focus generation]. 61
3145823 1988
6
[Visual epilepsy--4. Pattern activation and clinical and EEG findings]. 61
4473292 1974
7
[Visual epilepsy. 3. Red flicker stimulation activation and clinical and EEG findings]. 61
4798620 1973
8
[Visual epilepsy. 2. Off-PS activation and clinical and EEG findings]. 61
4798619 1973
9
[Visual epilepsy. 1. On, off activation and clinical-EEG findings]. 61
4737461 1973

Variations for Visual Epilepsy

Expression for Visual Epilepsy

Search GEO for disease gene expression data for Visual Epilepsy.

Pathways for Visual Epilepsy

Pathways related to Visual Epilepsy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.03 PPT1 MFSD8 CLN5 CLN3

GO Terms for Visual Epilepsy

Cellular components related to Visual Epilepsy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.91 PPT1 MFSD8 KCTD7 ERG28 DNAJC5 CLN8
2 endoplasmic reticulum GO:0005783 9.77 ERG28 CLN8 CLN6 CLN5 CLN3
3 membrane raft GO:0045121 9.5 PPT1 CLN6 CLN3
4 synaptic vesicle GO:0008021 9.33 PPT1 DNAJC5 CLN3
5 lysosome GO:0005764 9.26 PPT1 MFSD8 CLN5 CLN3
6 lysosomal membrane GO:0005765 8.92 MFSD8 DNAJC5 CLN5 CLN3

Biological processes related to Visual Epilepsy according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 visual perception GO:0007601 9.65 PPT1 CLN8 CLN6
2 negative regulation of neuron apoptotic process GO:0043524 9.58 PPT1 DNAJC5 CLN3
3 protein catabolic process GO:0030163 9.56 PPT1 CLN8 CLN6 CLN5
4 neuron development GO:0048666 9.55 PPT1 MFSD8
5 neurotransmitter secretion GO:0007269 9.54 PPT1 DNAJC5
6 adult locomotory behavior GO:0008344 9.52 PPT1 CLN8
7 neuromuscular process controlling balance GO:0050885 9.51 CLN8 CLN3
8 associative learning GO:0008306 9.5 PPT1 CLN8 CLN3
9 autophagosome maturation GO:0097352 9.49 MFSD8 CLN3
10 negative regulation of proteolysis GO:0045861 9.46 CLN8 CLN3
11 cellular protein catabolic process GO:0044257 9.43 PPT1 CLN8
12 positive regulation of pinocytosis GO:0048549 9.37 PPT1 CLN3
13 cellular macromolecule catabolic process GO:0044265 9.33 PPT1 CLN8 CLN6
14 lysosomal lumen acidification GO:0007042 9.26 PPT1 CLN6 CLN5 CLN3
15 lysosome organization GO:0007040 9.1 PPT1 MFSD8 CLN8 CLN6 CLN5 CLN3

Molecular functions related to Visual Epilepsy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lysophosphatidic acid binding GO:0035727 8.96 PPT1 CLN6
2 sulfatide binding GO:0120146 8.8 PPT1 CLN6 CLN3

Sources for Visual Epilepsy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....