MCID: VSL006
MIFTS: 7

Visual Pathway and Hypothalamic Glioma, Childhood

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Visual Pathway and Hypothalamic Glioma, Childhood

MalaCards integrated aliases for Visual Pathway and Hypothalamic Glioma, Childhood:

Name: Visual Pathway and Hypothalamic Glioma, Childhood 52

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


Summaries for Visual Pathway and Hypothalamic Glioma, Childhood

MalaCards based summary : Visual Pathway and Hypothalamic Glioma, Childhood The drugs Temozolomide and Carboplatin have been mentioned in the context of this disorder. Affiliated tissues include brain and eye.

Related Diseases for Visual Pathway and Hypothalamic Glioma, Childhood

Symptoms & Phenotypes for Visual Pathway and Hypothalamic Glioma, Childhood

Drugs & Therapeutics for Visual Pathway and Hypothalamic Glioma, Childhood

Drugs for Visual Pathway and Hypothalamic Glioma, Childhood (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Temozolomide Approved, Investigational Phase 1 85622-93-1 5394
2
Carboplatin Approved Phase 1 41575-94-4 10339178 498142 38904
3
Vincristine Approved, Investigational Phase 1 2068-78-2, 57-22-7 5978
4
Etoposide Approved Phase 1 33419-42-0 36462
5
Lenograstim Approved, Investigational Phase 1 135968-09-1
6
Irinotecan Approved, Investigational Phase 1 97682-44-5, 100286-90-6 60838
7
Valproic acid Approved, Investigational Phase 1 99-66-1 3121
8
Topotecan Approved, Investigational Phase 1 119413-54-6, 123948-87-8 60700
9 Protein Kinase Inhibitors Phase 1
10
Erlotinib Hydrochloride Phase 1 183319-69-9 176871
11 Alkylating Agents Phase 1
12 Antimitotic Agents Phase 1
13 Etoposide phosphate Phase 1
14 Neurotransmitter Agents Phase 1
15 Central Nervous System Depressants Phase 1
16 GABA Agents Phase 1
17 Anticonvulsants Phase 1
18 Antimanic Agents Phase 1
19 Tranquilizing Agents Phase 1
20 Psychotropic Drugs Phase 1
21 Topoisomerase Inhibitors Phase 1
22 topoisomerase I inhibitors Phase 1
23
Donepezil Approved Early Phase 1 120014-06-4 3152
24 Nootropic Agents Early Phase 1
25 Cholinergic Agents Early Phase 1
26 Cholinesterase Inhibitors Early Phase 1

Interventional clinical trials:

(show all 11)
# Name Status NCT ID Phase Drugs
1 Phase I Studies of TARCEVA™ (ERLOTINIB HYDROCHLORIDE, OSI-774) as Single Agent in Children With Refractory and Relapsed Malignant Brain Tumors and in Combination With Irradiation in Newly Diagnosed Brain Stem Glioma Unknown status NCT00360854 Phase 1 erlotinib hydrochloride
2 High Dose Carboplatin Combined With Oral VP-16 In The Treatment Of Pediatric CNS Malignancies Completed NCT00053118 Phase 1 carboplatin;etoposide
3 A Phase I Study of Temozolomide, Oral Irinotecan, and Vincristine for Children With Refractory Solid Tumors Completed NCT00138216 Phase 1 irinotecan hydrochloride;temozolomide;vincristine sulfate
4 A Phase I Study of Valproic Acid in Children With Recurrent/Progressive Solid Tumors Including CNS Tumors Completed NCT00107458 Phase 1 valproic acid
5 A Phase I Study of MK-0752 in Pediatric Patients With Recurrent or Refractory CNS Malignancies Terminated NCT00572182 Phase 1 MK-0752
6 A Phase I Pharmacokinetic Optimal Dosing Study of Intraventricular Topotecan for Children With Neoplastic Meningitis Terminated NCT00112619 Phase 1 topotecan hydrochloride
7 Translation Study for Children and Adolescents With Low Grade Glioma Unknown status NCT00891722
8 A Pilot Study Using Carboplatin, Vincristine And Temozolomide For Children ≤ 10 Years With Progressive/Symptomatic Low-Grade Gliomas Completed NCT00077207 carboplatin;temozolomide;vincristine sulfate
9 A Pilot Study of Donepezil Hydrochloride in Pediatric Brain Tumor Survivors After Cranial Irradiation Completed NCT00452868 Early Phase 1 Donepezil
10 Cooperative Multicenter Study for Children and Adolescents With Low Grade Glioma Completed NCT00276640 vincristine, carboplatin;vincristine, carboplatin, etoposide
11 Evaluation of Cerebral Spinal Fluid (CSF) Proteome and Angiogenesis Proteins in Children With Newly Diagnosed Central Nervous System Tumors Withdrawn NCT00897858

Search NIH Clinical Center for Visual Pathway and Hypothalamic Glioma, Childhood

Genetic Tests for Visual Pathway and Hypothalamic Glioma, Childhood

Anatomical Context for Visual Pathway and Hypothalamic Glioma, Childhood

MalaCards organs/tissues related to Visual Pathway and Hypothalamic Glioma, Childhood:

40
Brain, Eye

Publications for Visual Pathway and Hypothalamic Glioma, Childhood

Variations for Visual Pathway and Hypothalamic Glioma, Childhood

Expression for Visual Pathway and Hypothalamic Glioma, Childhood

Search GEO for disease gene expression data for Visual Pathway and Hypothalamic Glioma, Childhood.

Pathways for Visual Pathway and Hypothalamic Glioma, Childhood

GO Terms for Visual Pathway and Hypothalamic Glioma, Childhood

Sources for Visual Pathway and Hypothalamic Glioma, Childhood

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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