MCID: VSL005
MIFTS: 24

Visual Pathway Disease

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Visual Pathway Disease

MalaCards integrated aliases for Visual Pathway Disease:

Name: Visual Pathway Disease 12 15
Disorder of Visual Pathways 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1393
NCIt 49 C35342
SNOMED-CT 67 54767005
ICD10 32 H47.7 H47.9
UMLS 71 C0155287

Summaries for Visual Pathway Disease

Disease Ontology : 12 An eye disease that affects the neural pathway from the optic nerve to the visual cortex, through which light is interpreted as an image.

MalaCards based summary : Visual Pathway Disease, also known as disorder of visual pathways, is related to pearson marrow-pancreas syndrome and auditory agnosia. An important gene associated with Visual Pathway Disease is SLC26A5 (Solute Carrier Family 26 Member 5), and among its related pathways/superpathways are Mitochondrial protein import and NCAM1 interactions. Affiliated tissues include eye and cortex.

Related Diseases for Visual Pathway Disease

Graphical network of the top 20 diseases related to Visual Pathway Disease:



Diseases related to Visual Pathway Disease

Symptoms & Phenotypes for Visual Pathway Disease

Drugs & Therapeutics for Visual Pathway Disease

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Comparative Study Between Dissociative Treatment and Binocular Interactive Treatment in Amblyopia Recruiting NCT03255707

Search NIH Clinical Center for Visual Pathway Disease

Genetic Tests for Visual Pathway Disease

Anatomical Context for Visual Pathway Disease

MalaCards organs/tissues related to Visual Pathway Disease:

40
Eye, Cortex

Publications for Visual Pathway Disease

Articles related to Visual Pathway Disease:

(show all 17)
# Title Authors PMID Year
1
Homonymous Hemianopic Hyporeflective Retinal Abnormality on Infrared Confocal Scanning Laser Photography: A Novel Sign of Optic Tract Lesion. 61
26172159 2016
2
Clinical characteristics of children with severe visual impairment but favorable retinal structural outcomes from the Early Treatment for Retinopathy of Prematurity (ETROP) study. 61
23522948 2013
3
Severe visual impairment in children with mild or moderate retinal residua following regressed threshold retinopathy of prematurity. 61
17416324 2007
4
Scanning the ocular albinism 1 (OA1) gene for polymorphisms in congenital nystagmus by DHPLC. 61
16754205 2006
5
The prevalence of low vision and blindness in Canada. 61
15905873 2006
6
Sarcoidosis of the anterior visual pathway: 24 new cases. 61
14504590 2003
7
Photophobia in anterior visual pathway disease. 61
11937896 2002
8
The prevalence of strabismus in congenital nystagmus: the influence of anterior visual pathway disease. 61
10530980 1997
9
Monocular nystagmus caused by unilateral anterior visual-pathway disease. 61
8253290 1993
10
The correlation of visual function with posterior retinal structure in severe retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. 61
1580837 1992
11
Kestenbaum's number as an indicator of pupillomotor input asymmetry. 61
2712133 1989
12
Adrenoleukodystrophy: correlating MR imaging with CT. 61
3659373 1987
13
MR of visual pathways in patients with neurofibromatosis. 61
3118676 1987
14
Computer-assisted perimetry in visual pathway disease: neuro-ophthalmic applications. 61
6535331 1984
15
Diagnostic strategies in the management of unexplained visual loss. A cost-benefit analysis. 61
6820458 1981
16
Lipofuscin and transsynaptic degeneration. 61
153644 1978
17
Atypical retinitis pigmentosa masquerading as a nerve fiber bundle lesion. 61
1078938 1975

Variations for Visual Pathway Disease

Expression for Visual Pathway Disease

Search GEO for disease gene expression data for Visual Pathway Disease.

Pathways for Visual Pathway Disease

Pathways related to Visual Pathway Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.72 TIMM8A TIMM13 TIMM10B TIMM10
2 10.52 ST8SIA2 PRNP

GO Terms for Visual Pathway Disease

Cellular components related to Visual Pathway Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial inner membrane GO:0005743 9.65 TIMM8A TIMM29 TIMM13 TIMM10B TIMM10
2 TIM22 mitochondrial import inner membrane insertion complex GO:0042721 9.16 TIMM29 TIMM10B
3 mitochondrial intermembrane space protein transporter complex GO:0042719 9.13 TIMM13 TIMM10B TIMM10
4 mitochondrial intermembrane space GO:0005758 9.02 TIMM8A TIMM29 TIMM13 TIMM10B TIMM10

Biological processes related to Visual Pathway Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein transport GO:0015031 9.65 TIMM8A TIMM29 TIMM13 TIMM10B TIMM10
2 sensory perception of sound GO:0007605 9.5 TIMM13 TIMM10 SLC26A5
3 protein targeting to mitochondrion GO:0006626 9.33 TIMM13 TIMM10B TIMM10
4 chaperone-mediated protein transport GO:0072321 9.13 TIMM8A TIMM13 TIMM10
5 protein import into mitochondrial inner membrane GO:0045039 8.8 TIMM29 TIMM13 TIMM10

Sources for Visual Pathway Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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