MCID: VTM021
MIFTS: 13

Vitamin K Antagonists Toxicity or Dose Selection

Categories: Rare diseases

Aliases & Classifications for Vitamin K Antagonists Toxicity or Dose Selection

MalaCards integrated aliases for Vitamin K Antagonists Toxicity or Dose Selection:

Name: Vitamin K Antagonists Toxicity or Dose Selection 59

Classifications:



External Ids:

Orphanet 59 ORPHA413674

Summaries for Vitamin K Antagonists Toxicity or Dose Selection

MalaCards based summary : Vitamin K Antagonists Toxicity or Dose Selection is related to diffuse alveolar hemorrhage and phenytoin toxicity. Among its related pathways/superpathways are Arachidonic acid metabolism and Linoleic acid metabolism.

Related Diseases for Vitamin K Antagonists Toxicity or Dose Selection

Diseases related to Vitamin K Antagonists Toxicity or Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 diffuse alveolar hemorrhage 9.6 CYP2C9 VKORC1
2 phenytoin toxicity 9.5 CYP2C9 VKORC1
3 atrial fibrillation 8.9 CYP4F2 VKORC1
4 coumarin resistance 8.7 CYP2C9 CYP4F2 VKORC1

Symptoms & Phenotypes for Vitamin K Antagonists Toxicity or Dose Selection

Drugs & Therapeutics for Vitamin K Antagonists Toxicity or Dose Selection

Search Clinical Trials , NIH Clinical Center for Vitamin K Antagonists Toxicity or Dose Selection

Genetic Tests for Vitamin K Antagonists Toxicity or Dose Selection

Anatomical Context for Vitamin K Antagonists Toxicity or Dose Selection

Publications for Vitamin K Antagonists Toxicity or Dose Selection

Variations for Vitamin K Antagonists Toxicity or Dose Selection

Expression for Vitamin K Antagonists Toxicity or Dose Selection

Search GEO for disease gene expression data for Vitamin K Antagonists Toxicity or Dose Selection.

Pathways for Vitamin K Antagonists Toxicity or Dose Selection

GO Terms for Vitamin K Antagonists Toxicity or Dose Selection

Cellular components related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.33 CYP2C9 CYP4F2 VKORC1
2 endoplasmic reticulum membrane GO:0005789 9.13 CYP2C9 CYP4F2 VKORC1
3 organelle membrane GO:0031090 8.62 CYP2C9 CYP4F2

Biological processes related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.43 CYP2C9 CYP4F2 VKORC1
2 blood coagulation GO:0007596 9.32 CYP4F2 VKORC1
3 epoxygenase P450 pathway GO:0019373 9.16 CYP2C9 CYP4F2
4 omega-hydroxylase P450 pathway GO:0097267 8.96 CYP2C9 CYP4F2
5 drug metabolic process GO:0017144 8.8 CYP2C9 CYP4F2 VKORC1

Molecular functions related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 iron ion binding GO:0005506 9.37 CYP2C9 CYP4F2
2 heme binding GO:0020037 9.32 CYP2C9 CYP4F2
3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.26 CYP2C9 CYP4F2
4 monooxygenase activity GO:0004497 9.16 CYP2C9 CYP4F2
5 oxidoreductase activity GO:0016491 9.13 CYP2C9 CYP4F2 VKORC1
6 arachidonic acid epoxygenase activity GO:0008392 8.62 CYP2C9 CYP4F2

Sources for Vitamin K Antagonists Toxicity or Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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