MCID: VTM003
MIFTS: 20

Vitamin Metabolic Disorder

Categories: Metabolic diseases

Aliases & Classifications for Vitamin Metabolic Disorder

MalaCards integrated aliases for Vitamin Metabolic Disorder:

Name: Vitamin Metabolic Disorder 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050718

Summaries for Vitamin Metabolic Disorder

Disease Ontology : 12 An inherited metabolic disorder resulting from a deficiency in vitamin or vitamin cofactor transport or metabolism.

MalaCards based summary : Vitamin Metabolic Disorder is related to vitamin b12 deficiency and vitamin e, familial isolated deficiency of. An important gene associated with Vitamin Metabolic Disorder is GIF (Gastric Intrinsic Factor), and among its related pathways/superpathways are Metabolism and HIV Life Cycle.

Related Diseases for Vitamin Metabolic Disorder

Graphical network of the top 20 diseases related to Vitamin Metabolic Disorder:



Diseases related to Vitamin Metabolic Disorder

Symptoms & Phenotypes for Vitamin Metabolic Disorder

Drugs & Therapeutics for Vitamin Metabolic Disorder

Search Clinical Trials , NIH Clinical Center for Vitamin Metabolic Disorder

Genetic Tests for Vitamin Metabolic Disorder

Anatomical Context for Vitamin Metabolic Disorder

Publications for Vitamin Metabolic Disorder

Variations for Vitamin Metabolic Disorder

Expression for Vitamin Metabolic Disorder

Search GEO for disease gene expression data for Vitamin Metabolic Disorder.

Pathways for Vitamin Metabolic Disorder

Pathways related to Vitamin Metabolic Disorder according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.73 AMN CD320 CUBN GIF MMADHC MTHFR
2
Show member pathways
13.4 AMN CD320 CUBN GIF MMADHC MTR
3
Show member pathways
12.46 AMN CD320 CUBN GIF MMADHC MTHFR
4
Show member pathways
12.13 CUBN GIF MTHFR MTR MUT TCN1
5
Show member pathways
11.98 MTHFR MTR MUT
6
Show member pathways
11.78 MTHFR MTR TCN2
7
Show member pathways
11.19 AMN CD320 CUBN GIF MMADHC MTR
8 10.93 AMN CD320 CUBN GIF MMADHC MTR
9 10.92 CUBN GIF TCN2
10
Show member pathways
10.34 AMN CUBN GIF

GO Terms for Vitamin Metabolic Disorder

Cellular components related to Vitamin Metabolic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 9.5 AMN CUBN GIF
2 clathrin-coated pit GO:0005905 9.4 AMN CUBN
3 endocytic vesicle GO:0030139 9.37 AMN CUBN
4 endosome membrane GO:0010008 9.33 AMN CD320 CUBN
5 brush border membrane GO:0031526 9.26 AMN CUBN
6 endosome GO:0005768 9.26 AMN CUBN GIF TCN2
7 lysosomal lumen GO:0043202 8.8 CUBN GIF TCN2

Biological processes related to Vitamin Metabolic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin metabolic process GO:0009235 9.61 AMN CD320 CUBN GIF MMADHC MTR
2 cobalt ion transport GO:0006824 9.33 GIF TCN1 TCN2
3 high-density lipoprotein particle clearance GO:0034384 9.32 AMN CUBN
4 homocysteine metabolic process GO:0050667 9.26 MTHFR MUT
5 cobalamin transport GO:0015889 9.1 AMN CD320 CUBN GIF TCN1 TCN2

Molecular functions related to Vitamin Metabolic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin binding GO:0031419 9.17 CD320 CUBN GIF MTR MUT TCN1
2 modified amino acid binding GO:0072341 8.96 MTHFR MUT

Sources for Vitamin Metabolic Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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