MCID: VRC006
MIFTS: 8

Voriconazole Toxicity

Categories: Rare diseases

Aliases & Classifications for Voriconazole Toxicity

MalaCards integrated aliases for Voriconazole Toxicity:

Name: Voriconazole Toxicity 58

Classifications:



External Ids:

Orphanet 58 ORPHA240921

Summaries for Voriconazole Toxicity

MalaCards based summary : Voriconazole Toxicity is related to ataxia and polyneuropathy, adult-onset and aspergillosis. An important gene associated with Voriconazole Toxicity is CYP2C19 (Cytochrome P450 Family 2 Subfamily C Member 19). Affiliated tissues include lung.

Related Diseases for Voriconazole Toxicity

Diseases related to Voriconazole Toxicity via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 ataxia and polyneuropathy, adult-onset 9.9
2 aspergillosis 9.9
3 toxic shock syndrome 9.9

Symptoms & Phenotypes for Voriconazole Toxicity

Drugs & Therapeutics for Voriconazole Toxicity

Search Clinical Trials , NIH Clinical Center for Voriconazole Toxicity

Genetic Tests for Voriconazole Toxicity

Anatomical Context for Voriconazole Toxicity

MalaCards organs/tissues related to Voriconazole Toxicity:

40
Lung

Publications for Voriconazole Toxicity

Articles related to Voriconazole Toxicity:

# Title Authors PMID Year
1
Disseminated cerebral aspergillosis complicated by thrombotic microangiopathy. 61
31334000 2019
2
VORICONAZOLE TOXICITY IN MULTIPLE PENGUIN SPECIES. 61
26667545 2015
3
Voriconazole toxicity masquerading as septic shock. 61
25139693 2015
4
Voriconazole metabolism, toxicity, and the effect of cytochrome P450 2C19 genotype. 61
24403552 2014
5
Genetic variation in plant CYP51s confers resistance against voriconazole, a novel inhibitor of brassinosteroid-dependent sterol biosynthesis. 61
23335967 2013
6
Observational study of the clinical efficacy of voriconazole and its relationship to plasma concentrations in patients. 61
21768513 2011
7
Voriconazole toxicity related to polymorphisms in CYP2C19. 61
21507170 2011
8
Effect of cytochrome P450 2C19 genotype on voriconazole exposure in cystic fibrosis lung transplant patients. 61
21038076 2011
9
Hallucinations during voriconazole therapy. 61
18491963 2008

Variations for Voriconazole Toxicity

Expression for Voriconazole Toxicity

Search GEO for disease gene expression data for Voriconazole Toxicity.

Pathways for Voriconazole Toxicity

GO Terms for Voriconazole Toxicity

Sources for Voriconazole Toxicity

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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