Vulva Squamous Cell Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: VLV034 MIFTS: 33	Vulva Squamous Cell Carcinoma Categories: Reproductive diseases, Rare diseases, Cancer diseases, Skin diseases
Genes Variations Tissues Related diseases Publications Pathways Drugs Download Expand all tables

Sources

Aliases & Classifications for Vulva Squamous Cell Carcinoma

MalaCards integrated aliases for Vulva Squamous Cell Carcinoma:

Name: Vulva Squamous Cell Carcinoma ¹² ¹⁵

Squamous Cell Carcinoma of Vulva ¹² ⁷³

Vulvar Squamous Cell Carcinoma ¹² ⁵⁹

Squamous Cell Carcinoma of the Vulva ⁵⁹

Vulvar Epidermoid Carcinoma ¹²

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases
Anatomical: Reproductive diseases Skin diseases

See all MalaCards categories (disease lists)

Orphanet: ⁵⁹

Rare gynaecological and obstetric diseases

External Ids:

Disease Ontology ¹² DOID:2101

NCIt ⁵⁰ C4052

SNOMED-CT ⁶⁸ 254895003

Orphanet ⁵⁹ ORPHA494448

UMLS ⁷³ C0280856

Sources

Summaries for Vulva Squamous Cell Carcinoma

Disease Ontology : ¹² A vulva carcinoma and has material basis in squamous cells and is located in the epidermis of the vulvar tissue.

MalaCards based summary : Vulva Squamous Cell Carcinoma, also known as squamous cell carcinoma of vulva, is related to squamous cell carcinoma and prostate disease. An important gene associated with Vulva Squamous Cell Carcinoma is MEG3 (Maternally Expressed 3
LncRNAs (MEG3 and MALAT1) were also identified as potential biomarkers as they also correlated with VSCC carcinogenesis.
Dysfunction Pattern: Expression), and among its related pathways/superpathways are Photodynamic therapy-induced AP-1 survival signaling. and Oncogene Induced Senescence. The drugs Cisplatin and Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include the epidermis of the vulvar tissue, lymph node and skin.

Sources

Related Diseases for Vulva Squamous Cell Carcinoma

Diseases related to Vulva Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)

#	Related Disease	Score	Top Affiliating Genes
1	squamous cell carcinoma	29.3	CDKN2A MALAT1 SERPINB3 TP53
2	prostate disease	10.8	MALAT1 MEG3
3	malignant glioma	10.7	MALAT1 MEG3
4	brain stem astrocytic neoplasm	10.7	CDKN2A TP53
5	keratinizing squamous cell carcinoma	10.7	CDKN2A TP53
6	spitz nevus	10.7	CDKN2A TP53
7	bladder carcinoma in situ	10.6	CDKN2A TP53
8	bartholin's gland benign neoplasm	10.6	CDKN2A TP53
9	thyroid lymphoma	10.6	CDKN2A TP53
10	nasal cavity adenocarcinoma	10.6	CDKN2A TP53
11	bone squamous cell carcinoma	10.6	CDKN2A TP53
12	pituitary adenoma	10.6	MALAT1 MEG3
13	scrotal carcinoma	10.6	CDKN2A TP53
14	anal squamous cell carcinoma	10.6	CDKN2A TP53
15	glycogen-rich clear cell breast carcinoma	10.6	CDKN2A TP53
16	gastric adenosquamous carcinoma	10.6	CDKN2A TP53
17	oral leukoplakia	10.6	CDKN2A TP53
18	anogenital venereal wart	10.6	CDKN2A TP53
19	megaesophagus	10.6	CDKN2A TP53
20	ovarian epithelial cancer	10.6	MALAT1 MEG3
21	cervix uteri carcinoma in situ	10.6	CDKN2A TP53
22	schneiderian carcinoma	10.6	CDKN2A TP53
23	meningeal melanomatosis	10.6	CDKN2A TP53
24	dedifferentiated liposarcoma	10.6	CDKN2A TP53
25	suppressor of tumorigenicity 3	10.6	CDKN2A TP53
26	embryonal sarcoma	10.6	MALAT1 TP53
27	oropharynx cancer	10.6	CDKN2A TP53
28	endocervical adenocarcinoma	10.6	CDKN2A TP53
29	cervix small cell carcinoma	10.6	CDKN2A TP53
30	necrotizing sialometaplasia	10.6	CDKN2A TP53
31	basaloid squamous cell carcinoma	10.6	CDKN2A TP53
32	biliary tract neoplasm	10.6	CDKN2A TP53
33	optic nerve neoplasm	10.5	CDKN2A TP53
34	recessive dystrophic epidermolysis bullosa	10.5	CDKN2A TP53
35	squamous cell papilloma	10.5	CDKN2A TP53
36	pre-malignant neoplasm	10.5	CDKN2A TP53
37	juvenile pilocytic astrocytoma	10.5	CDKN2A TP53
38	barrett's adenocarcinoma	10.5	CDKN2A TP53
39	cervix carcinoma	10.5	CDKN2A TP53
40	tonsil cancer	10.5	CDKN2A SERPINB3
41	gastrointestinal system benign neoplasm	10.5	CDKN2A TP53
42	skin squamous cell carcinoma	10.5	CDKN2A TP53
43	cellular schwannoma	10.5	CDKN2A TP53
44	penile cancer	10.4	CDKN2A TP53
45	anal canal squamous cell carcinoma	10.4	CDKN2A SERPINB3
46	pancreatic ductal carcinoma	10.4	CDKN2A TP53
47	bladder squamous cell carcinoma	10.4	CDKN2A TP53
48	in situ carcinoma	10.4	CDKN2A TP53
49	central nervous system lymphoma	10.4	CDKN2A TP53
50	anus cancer	10.4	CDKN2A SERPINB3

Graphical network of the top 20 diseases related to Vulva Squamous Cell Carcinoma:

Sources

Symptoms & Phenotypes for Vulva Squamous Cell Carcinoma

Sources

Drugs & Therapeutics for Vulva Squamous Cell Carcinoma

Drugs for Vulva Squamous Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Cisplatin

Approved

Phase 3,Phase 2,Phase 1

15663-27-1

84093 441203 2767

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatine

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

Paclitaxel

Approved, Vet_approved

Phase 2

33069-62-4

36314

Synonyms:

(2AR-(2aalpha,4b,4abeta,6b,9a(a r*,betas*),11a,12a,12balpha))-b-(benzoylamino)-a-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4b,4abeta,6b,9a(a r*,betas*),11a,12a,12balpha))-b-(benzoylamino)-a-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4β,4abeta,6β,9α(α r*,betas*),11α,12α,12balpha))-β-(benzoylamino)-α-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4β,4abeta,6β,9α(α r*,betas*),11α,12α,12balpha))-β-(benzoylamino)-α-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

157069-30-2

33069-62-4

5b,20-Epoxy-1,2-a,4,7b,10b,13a-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5b,20-Epoxy-1,2-a,4,7b,10b,13a-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5β,20-epoxy-1,2-α,4,7β,10β,13α-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5β,20-epoxy-1,2-α,4,7β,10β,13α-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

7 Epi taxol

7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.

7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.

7-epi-Paclitaxel

7-Epipaclitaxel

7-Epi-paclitaxel

7-epi-Taxol

7-Epitaxol

7-Epi-taxol

AB00513812

ABI 007

abi-007

ABI007

ABI-007

Abraxane

Abraxane (TN)

Abraxane I.V. Suspension

Abraxis BioScience brand of albumin-bound paclitaxel

AC1L1IOG

AC1L1VJI

AC1L9AVF

AC-675

ACon1_002231

albumin-bound paclitaxel

Ambotz33069-62-4

ANX-513

Anzatax

Asotax

BIDD:PXR0046

Bio-0076

Bio1_000362

Bio1_000851

Bio1_001340

Bio2_000416

Bio2_000896

BMS 181339-01

BMS-181339

BMS-181339-01

BPBio1_000320

BRD-A23723433-001-01-2

BRD-A28746609-001-04-0

BRD-K62008436-001-03-1

Bris taxol

Bristaxol

BSPBio_000290

BSPBio_001152

BSPBio_002614

C07394

C466458

C47H51NO14

Capxol

CCRIS 8143

CHEBI:103439

CHEBI:45863

CHEMBL100910

CHEMBL418410

CHEMBL48

CID36314

CID441276

CID4666

CID6713921

CID6915727

cMAP_000068

CPD-8718

D00491

DB01229

DHP-107

DHP-208

DivK1c_000441

DRG-0190

DTS-301

Ebetaxel

EmPAC

Epitaxol

EU-0101201

Genaxol

Genetaxyl

Genexol

Genexol-PM

HMS1362J13

HMS1568O12

HMS1792J13

HMS1922K08

HMS1990J13

HMS2090D07

HMS2093K15

HMS501G03

HSDB 6839

I06-0014

IDI1_000441

IDI1_002171

Intaxel

KBio1_000441

KBio2_000492

KBio2_002016

KBio2_002509

KBio2_003060

KBio2_004584

KBio2_005077

KBio2_005628

KBio2_007152

KBio2_007645

KBio3_000903

KBio3_000904

KBio3_001834

KBio3_002987

KBioGR_000492

KBioGR_001893

KBioGR_002509

KBioSS_000492

KBioSS_002016

KBioSS_002517

LipoPac

LMPR0104390001

Lopac0_001201

LS-31070

MBT 0206

MEGxp0_001940

Micellar Paclitaxel

Mitotax

MLS000863266

MLS001077297

MLS002154218

MLS002172439

MLS002695976

MolPort-001-742-627

MolPort-003-665-783

MolPort-003-932-365

MPI-5018

nab-paclitaxel

Nanotaxel

NCGC00024995-02

NCGC00024995-03

NCGC00024995-04

NCGC00024995-05

NCGC00024995-06

NCGC00024995-07

NCGC00164367-01

NCGC00164367-02

NCGC00164367-03

nchembio.188-comp1

nchembio.2007.34-comp9

nchembio.215-comp9

nchembio853-comp6

NCI60_000601

Neuro_000060

NINDS_000441

NK 105

Nova-12005

NP-010981

NSC 125973

NSC125973

NSC-125973

NSC358882

OAS-PAC-100

OncoGel

Onxal

Onxol

Onxol, Taxol, Nov-Onxol, Paclitaxel

P1632

Paclical

Pacligel

paclitaxel

Paclitaxel

Paclitaxel (JAN/USP)

Paclitaxel (JAN/USP/INN)

Paclitaxel (Taxol)

Paclitaxel [USAN:INN:BAN]

Paclitaxel, (4 alpha)-isomer

Paxceed

Paxene

Paxoral

Plaxicel

Praxel

Prestwick0_000155

Prestwick1_000155

Prestwick2_000155

Prestwick3_000155

Probes2_000350

QW 8184

S1150_Selleck

S-8184 Paclitaxel Injectable Emulsion

SDCCGMLS-0066823.P001

SDP-013

SMP1_000228

SMR000394086

SMR000857385

SPBio_000943

SPBio_002229

Spectrum_001536

SPECTRUM1503908

Spectrum2_000872

Spectrum3_001057

Spectrum4_001197

Spectrum5_001491

ST50306996

T 7402

T1912_SIGMA

T7191_SIGMA

T7402_SIGMA

TA1

TaxAlbin

Taxol

TAXOL

TAXOL (TN)

Taxol a

Taxol A

Taxol Konzentrat

TAXOL, 10-EPI,

Taxol, bris

Taxol.RTM. (Registered Trademark)

TXL

UNII-P88XT4IS4D

UPCMLD-DP108:001

UPCMLD-DP108:002

Vascular Wrap

weekly paclitaxel

Xorane

Yewtaxan

Gemcitabine

Approved

Phase 2

95058-81-4

60750

Synonyms:

103882-84-4

122111-03-9

2',2'-DFDC

2',2'-DiF-dC

2',2'-difluoro-2'-Deoxycytidine

2',2'-Difluoro-2'-deoxycytidine

2',2'-Difluorodeoxycytidine

2'-Deoxy-.beta.-D-2',2'-difluorocytidine

2'-Deoxy-2',2'-difluorocytidine

2'-Deoxy-2',2''-difluorocytidine-5'-O-monophosphate

2'-Deoxy-2'-difluorocytidine

4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-amino-1-((2R,4R,5R)-3,3-difluoro-4-Hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one

95058-81-4

AB1004842

AC1L1TUQ

C07650

CCRIS 8984

CHEBI:175901

CHEMBL888

CID60750

Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine

D02368

DB00441

DDFC

DFdC

DFDC

DFdCyd

Folfugem

Gamcitabine

Gemcel

Gemcin

Gemcitabin

Gemcitabina

Gemcitabina [INN-Spanish]

gemcitabine

Gemcitabine

Gemcitabine (USAN/INN)

Gemcitabine HCl

Gemcitabine hydrochloride

Gemcitabine stereoisomer

Gemcitabine, (alpha-D-threo-pentofuranosyl)-isomer

Gemcitabine, (beta-D-threo-pentafuranosyl)-isomer

Gemcitabine, (D-threo-pentafuranosyl)-isomer

Gemcitabinum

Gemcitabinum [INN-Latin]

GemLip

Gemtro

Gemzar

Gemzar (hydrochloride)

GEO

HMS2089P10

HSDB 7567

Inno-D07001

LS-59139

LY 188011

LY188011

LY-188011

NCGC00168784-01

NChemBio.2007.10-comp25

nchembio.573-comp7

nchembio.90-comp2

NSC 613327

NSC613327

TL8005979

UNII-B76N6SBZ8R

Zefei

ZINC18279854

nivolumab

Approved

Phase 2

946414-94-4

Erlotinib Hydrochloride

Phase 2

183319-69-9

176871

Protein Kinase Inhibitors

Phase 2

Albumin-Bound Paclitaxel

Phase 2

Antimitotic Agents

Phase 2

Antineoplastic Agents, Phytogenic

Phase 2

Antibodies

Phase 2

Immunoglobulins

Phase 2

Anti-Infective Agents

Phase 2

Antimetabolites

Phase 2

Antimetabolites, Antineoplastic

Phase 2

Antiviral Agents

Phase 2

Immunosuppressive Agents

Phase 2

Antibodies, Monoclonal

Phase 2

Formaldehyde

Approved, Vet_approved

50-00-0

712

Synonyms:

Aldeide formica

Fannoform

Formaldehyd

Formaldehyde solution

Formalin

FORMALIN

Formalina

Formaline

Formalith

Formic aldehyde

Formol

Methaldehyde

Methanal

Methyl aldehyde

Methylene glycol

Methylene oxide

Oxomethane

Oxomethylene

Oxymethylene

Paraform

Paraformaldehyde

Dimenhydrinate

Approved

523-87-5

441281

Synonyms:

(O-Benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate

2-(diphenylmethoxy)-N,N-dimethylethanaminium 8-chloro-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide

2-benzhydryloxyethyl(dimethyl)azanium

8-chloro-1,3-dimethyl-2-oxopurin-6-olate

8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)

8-chloro-1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)

AC1L9AVV

Benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline

beta-Dimethylaminoethyl benzhydryl ether 1,3-dimethyl-8-chloroxanthine

CAS-523-87-5

CHEBI:4604

CID441281

D00520

DB00985

Dimenhidrinato

Dimenhydrinate (JP15/USP/INN)

Dimenhydrinatum

Diphenhydramine 8-chlorotheophyllinate

Diphenhydramine 8-chlorotheophylline

Diphenhydramine theoclate

Diphenhydrinate

Dramamine (TN)

HMS1568F12

N,N-Dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate

NCGC00017026-01

O-Benzhydryldimethylaminoethanol 8-chlorotheophyllinate

Prestwick_892

Ethanol

Approved

64-17-5

702

Synonyms:

(C6-C9)Alkyl alcohol

[CH2Me(OH)]

[OEtH]

02483_FLUKA

02851_FLUKA

02853_FLUKA

02854_FLUKA

02855_FLUKA

02856_FLUKA

02856_SIAL

02857_FLUKA

02857_SIAL

02858_FLUKA

02858_SIAL

02860_FLUKA

02865_FLUKA

02865_SIAL

02870_FLUKA

02870_SIAL

02875_FLUKA

02877_FLUKA

02878_FLUKA

02882_FLUKA

02882_SIAL

02883_FLUKA

02884_FLUKA

02890_FLUKA

02890_SIAL

02891_FLUKA

02891_SIAL

100C.NPA

121182-78-3

187380_ALDRICH

187380_SIAL

1-Hydroxyethane

24102_RIEDEL

24102_SIAL

24103_RIEDEL

24103_SIAL

24105_RIEDEL

24105_SIAL

24106_RIEDEL

24106_SIAL

24194_RIEDEL

24194_SIAL

245119_ALDRICH

245119_SIAL

270741_ALDRICH

270741_SIAL

277649_ALDRICH

277649_SIAL

2858_SIGMA

29221_FLUKA

32205_RIEDEL

32205_SIAL

32221_RIEDEL

32221_SIAL

32294_RIEDEL

32294_SIAL

34870_SIAL

34963_RIEDEL

39278_FLUKA

40210_ALDRICH

40210_RIEDEL

41322_FLUKA

458600_ALDRICH

458600_SIAL

459828_ALDRICH

459828_SIAL

459836_ALDRICH

459836_SIAL

459844_SIAL

48075_SUPELCO

493511_SIAL

493538_ALDRICH

493538_SIAL

493546_ALDRICH

493546_SIAL

64-17-5

676829_SIAL

68475-56-9

71076-86-3

71329-38-9

8000-16-6

8024-45-1

absolute alcohol

Absolute alcohol

Absolute Alcohol

Absolute ethanol

Absolute Ethanol

Absolute ethyl alcohol

AC1L19TW

AC1Q31MM

Aethanol

Aethanol [German]

Aethylalkohol

AHD 2000

AI3-01706

Alcare hand degermer

Alcare Hand Degermer

alcohol

Alcohol

Alcohol (ethyl)

Alcohol (USP)

Alcohol [USP]

ALCOHOL 5% IN D5-W

Alcohol anhydrous

Alcohol Anhydrous

Alcohol dehydrated

Alcohol denatured

alcohol etilico

Alcohol etilico

Alcohol etílico

Alcohol, absolute

Alcohol, Absolute

Alcohol, anhydrous

Alcohol, dehydrated

Alcohol, Dehydrated

Alcohol, denatured

Alcohol, diluted

Alcohol, Diluted

Alcohol, ethyl

Alcohol, grain

Alcohol, Grain

Alcohols

Alcohols, C1-3

Alcohols, C30

Alcohols, C6-9

Alcool ethylique

Alcool Ethylique

Alcool éthylique

Alcool etilico

Alcool Etilico

Algrain

Alkohol

Alkohol [German]

Alkoholu etylowego

Alkoholu Etylowego

Aminoethanol

Anhydrol

Anhydrol PM 4085

Anhydrous alcohol

Anhydrous ethanol

Äthanol

Äthylalkohol

Beta-Aminoethanol

Beta-Aminoethyl Alcohol

Beta-Ethanolamine

Beta-Hydroxyethylamine

bmse000297

C00469

C2H5OH

C2H6O

Caswell No. 426

Caswell No. 430

CCRIS 945

CDA 19

CDA 19-200

CHEBI:16236

CHEMBL545

CID702

Colamine

Cologne spirit

Cologne Spirit

Cologne spirits

D000431

D00068

DB00898

Dehydrated alcohol

Dehydrated ethanol

Dehydrated Ethanol

Denatured alcohol

Denatured Alcohol

Denatured Alcohol Cd-10

Denatured Alcohol Cd-5

Denatured Alcohol Cd-5a

Denatured Alcohol Sd-1

Denatured Alcohol Sd-13a

Denatured Alcohol Sd-17

Denatured Alcohol Sd-23a

Denatured Alcohol Sd-28

Denatured Alcohol Sd-30

Denatured Alcohol Sd-39b

Denatured Alcohol Sd-39c

Denatured Alcohol Sd-3a

Denatured Alcohol Sd-40m

Denatured ethanol

Denatured Ethanol

Desinfektol el

Desinfektol EL

Diluted alcohol

Distilled spirits

E2385_SIGMA

E7023_ALDRICH

E7023_SIAL

E7148_ALDRICH

E7148_SIAL

E7517_SIGMA

EINECS 200-578-6

EINECS 270-649-4

Envision Conditioner Pdd 9020

EOH

EOX

Esumiru WK 88

ETA

etanol

Etanol

Etanolo

Etanolo [Italian]

ethanol

éthanol

Ethanol (9CI)

Ethanol [JAN]

Ethanol 200 proof

Ethanol 200 Proof

Ethanol Absolute

Ethanol Absolute Bp

Ethanol Anhydrous

Ethanol Extra Pure

Ethanol solution

Ethanol Vapor

Ethanol, Silent Spirit

Ethanol, undenatured

Ethanolum anhydricum

Ethicap

Ethyl alc

ethyl alcohol

Ethyl alcohol

Ethyl Alcohol

Ethyl Alcohol & Water, 10%

Ethyl Alcohol & Water, 20%

Ethyl Alcohol & Water, 30%

Ethyl Alcohol & Water, 40%

Ethyl Alcohol & Water, 5%

Ethyl Alcohol & Water, 50%

Ethyl Alcohol & Water, 60%

Ethyl Alcohol & Water, 70%

Ethyl Alcohol & Water, 80%

Ethyl Alcohol & Water, 95%

Ethyl Alcohol & Water, 96%

Ethyl alcohol anhydrous

Ethyl Alcohol Anhydrous

Ethyl alcohol in alcoholic beverages

Ethyl alcohol usp

Ethyl Alcohol, Anhydrous

Ethyl Alcohol, Denatured

Ethyl hydrate

Ethyl Hydrate

Ethyl hydroxide

Ethyl Hydroxide

Ethylalcohol

Ethylalcohol [Dutch]

Ethylol

Ethylolamine

Ethyloxy Group

EtOH

Etylowy alkohol

FEMA No. 2419

FEMA Number 2419

Fermentation alcohol

Glycinol

grain alcohol

Grain alcohol

Hinetoless

HSDB 531

HSDB 82

Hydroxyethane

HYDROXYETHYL GROUP

I14-12648

IMS 99

Infinity pure

Infinity Pure

Jaysol

Jaysol S

LS-1539

LTBB002977

Lux

Methylated spirit

Methylated Spirit Mineralised

Methylcarbinol

Molasses alcohol

MolPort-001-785-844

NCGC00091458-01

nchem.651-comp3c

nchembio.552-comp10

nchembio.94-comp20

NCI-C03134

NSC 85228

NSC85228

Oxydimethylene Group

potato Alcohol

Potato alcohol

Punctilious ethyl alcohol

Pyro

QMHAIh@

Reagent Alcohol

Ru-Tuss Expectorant

SDA 3A

SDA 40-2

SDM No. 37

Sekundasprit

Silent spirit

Spirit

Spirits of wine

Spirits OF wine

spiritus vini

Spiritus vini

Spirt

SY Fresh M

Synasol

Tecsol

Tecsol C

Thanol

Thiofaco M-50

Undenatured ethanol

UNII-3K9958V90M

USAF EK-1597

WLN: Q2

Hydrogen peroxide

Approved, Vet_approved

7722-84-1

784

Synonyms:

[OH(OH)]

Adeka super el

Albone

Albone 35

Albone DS

Anti-keim 50

Asepticper

Baquashock

CIX

Clarigel gold

Crestal whitestrips

Crystacide

Dentasept

Deslime LP

Dihydrogen dioxide

H2O2

Hioxyl

Hipox

HOOH

Hybrite

Hydrogen dioxide

Hydrogen peroxide (H2O2)

Hydroperoxide

Inhibine

Lase peroxide

Lensan a

Magic bleaching

Metrokur

Mirasept

Nite white excel 2

Odosat D

Opalescence xtra

Oxigenal

Oxydol

Oxyfull

Oxysept

Oxysept I

Pegasyl

Perhydrol

Perone

Peroxaan

Peroxclean

Peroxide, hydrogen

Quasar brite

Select bleach

Superoxol

T-Stuff

Whiteness HP

Whitespeed

Xtra white

Pharmaceutical Solutions

Interventional clinical trials:

(show all 14)

#	Name	Status	NCT ID	Phase	Drugs
1	Radiation Therapy or Surgery in Treating Patients With Previously Untreated Vulva Cancer With Positive Groin Lymph Nodes	Completed	NCT00898352	Phase 3
2	Lymphatic Mapping in Treating Patients With Stage I or Stage II Cancer of the Vulva	Completed	NCT00003325	Phase 3
3	Radiation Therapy With or Without Cisplatin in Treating Patients With Stage I, Stage II, or Stage III Cancer of the Vulva	Terminated	NCT00006096	Phase 3	cisplatin
4	Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Cancer of the Vulva	Completed	NCT00068406	Phase 2	Cisplatin
5	Erlotinib in Women With Squamous Cell Carcinoma of the Vulvar	Completed	NCT00476476	Phase 2	Erlotinib
6	Paclitaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Cancer of the Vulva	Completed	NCT00014599	Phase 2	paclitaxel
7	Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Cancer of the Vulva	Recruiting	NCT01595061	Phase 2	Cisplatin;Gemcitabine Hydrochloride
8	Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers	Recruiting	NCT02978625	Phase 2
9	Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vulvar Cancer	Suspended	NCT02595879	Phase 1	Cisplatin;Triapine
10	Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their Precursors	Unknown status	NCT02735109	Not Applicable
11	Conservative Management With Isolated Sentinel Lymph Node Biopsy in Vulvar Cancer Patients.	Completed	NCT00315159	Not Applicable
12	Collecting Tumor Samples From Patients With Gynecological Tumors	Completed	NCT00897442
13	OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer	Completed	NCT00900302
14	Observation in Patients With Early-Stage Vulvar Cancer Undergoing Sentinel Lymph Node Dissection	Active, not recruiting	NCT01500512

Search NIH Clinical Center for Vulva Squamous Cell Carcinoma

Sources

Genetic Tests for Vulva Squamous Cell Carcinoma

Sources

Anatomical Context for Vulva Squamous Cell Carcinoma

The Foundational Model of Anatomy Ontology organs/tissues related to Vulva Squamous Cell Carcinoma:

¹⁹

The Epidermis Of The Vulvar Tissue

MalaCards organs/tissues related to Vulva Squamous Cell Carcinoma:

⁴¹

Lymph Node, Skin

Sources

Publications for Vulva Squamous Cell Carcinoma

Articles related to Vulva Squamous Cell Carcinoma:

#	Title	Authors	Year
1	Tumor-to-tumor metastasis with endometrial carcinoma metastatic to squamous cell carcinoma of vulva: the first reported case. ( 24283863 )	Wimmer J.L....Ro J.Y.	2013
2	The definition of optimal inguinal femoral nodal dissection in the management of vulva squamous cell carcinoma. ( 17473950 )	Le T....Fung-Kee-Fung M.	2007

Sources

Genes for Vulva Squamous Cell Carcinoma

Genes related to Vulva Squamous Cell Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	MEG3	Maternally Expressed 3 LncRNAs (MEG3 and MALAT1) were also identified as potential biomarkers as they also correlated with VSCC carcinogenesis. Dysfunction Pattern: Expression	RNA Gene	150	Experimental evidence: Expression ³⁹	27633334
2	MALAT1	Metastasis Associated Lung Adenocarcinoma Transcript 1 LncRNAs (MEG3 and MALAT1) were also identified as potential biomarkers as they also correlated with VSCC carcinogenesis. Dysfunction Pattern: Expression	RNA Gene	150	Experimental evidence: Expression ³⁹	27633334
3	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	16.35	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	TP53	Tumor Protein P53	Protein Coding	15.66	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	PLXDC2	Plexin Domain Containing 2	Protein Coding	15.26	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	SH3GL2	SH3 Domain Containing GRB2 Like 2, Endophilin A1	Protein Coding	14.85	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	SERPINB3	Serpin Family B Member 3	Protein Coding	14.47	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	CD109	CD109 Molecule	Protein Coding	14.45	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	CASP14	Caspase 14	Protein Coding	14.36	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	ARID2	AT-Rich Interaction Domain 2	Protein Coding	14.32	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

Sources

Variations for Vulva Squamous Cell Carcinoma

Cosmic variations for Vulva Squamous Cell Carcinoma:

⁹

(show top 50) (show all 130)

#	Cosmic Mut ID	Gene Symbol	COSMIC Disease Classification (Primary site, Site subtype, Primary histology, Histology subtype)	Mutation CDS	Mutation AA	GRCh38 Location	Conf
1	COSM10662	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.743G>A	p.R248Q	17:7674220-7674220	17
2	COSM10905	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.451C>T	p.P151S	17:7675161-7675161	17
3	COSM44645	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.527G>C	p.C176S	17:7675085-7675085	17
4	COSM6932	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.733G>A	p.G245S	17:7674230-7674230	17
5	COSM10659	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.817C>T	p.R273C	17:7673803-7673803	17
6	COSM10656	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.742C>T	p.R248W	17:7674221-7674221	17
7	COSM10660	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.818G>A	p.R273H	17:7673802-7673802	17
8	COSM10724	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.839G>C	p.R280T	17:7673781-7673781	17
9	COSM10648	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.524G>A	p.R175H	17:7675088-7675088	17
10	COSM43559	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.517G>T	p.V173L	17:7675095-7675095	17
11	COSM45114	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.702C>A	p.Y234*	17:7674261-7674261	17
12	COSM10867	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.797G>A	p.G266E	17:7673823-7673823	17
13	COSM44365	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.607G>T	p.V203L	17:7674924-7674924	17
14	COSM10726	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.856G>A	p.E286K	17:7673764-7673764	17
15	COSM10790	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.455C>T	p.P152L	17:7675157-7675157	17
16	COSM43861	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.502C>T	p.H168Y	17:7675110-7675110	17
17	COSM44319	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.405C>A	p.C135*	17:7675207-7675207	17
18	COSM43734	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.528C>A	p.C176*	17:7675084-7675084	17
19	COSM43905	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.590T>G	p.V197G	17:7674941-7674941	17
20	COSM10667	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.646G>A	p.V216M	17:7674885-7674885	17
21	COSM45679	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.868C>T	p.R290C	17:7673752-7673752	17
22	COSM10704	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.844C>T	p.R282W	17:7673776-7673776	17
23	COSM10768	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.535C>T	p.H179Y	17:7675077-7675077	17
24	COSM43837	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.843C>G	p.D281E	17:7673777-7673777	17
25	COSM10722	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.853G>A	p.E285K	17:7673767-7673767	17
26	COSM11133	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.725G>C	p.C242S	17:7674238-7674238	17
27	COSM11998	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.534C>A	p.H178Q	17:7675078-7675078	17
28	COSM10663	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.916C>T	p.R306*	17:7673704-7673704	17
29	COSM43657	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.569C>T	p.P190L	17:7674962-7674962	17
30	COSM43955	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.514G>A	p.V172I	17:7675098-7675098	17
31	COSM44942	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.339C>G	p.F113L	17:7676030-7676030	17
32	COSM44808	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.503A>C	p.H168P	17:7675109-7675109	17
33	COSM11073	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.1024C>T	p.R342*	17:7670685-7670685	17
34	COSM10812	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.722C>T	p.S241F	17:7674241-7674241	17
35	COSM6845277	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.670G>C	p.E224Q	17:7674861-7674861	17
36	COSM43818	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.413C>T	p.A138V	17:7675199-7675199	17
37	COSM10735	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.638G>A	p.R213Q	17:7674893-7674893	17
38	COSM44120	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.532C>T	p.H178Y	17:7675080-7675080	17
39	COSM44383	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.518T>G	p.V173G	17:7675094-7675094	17
40	COSM44094	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.716A>G	p.N239S	17:7674247-7674247	17
41	COSM10647	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.404G>T	p.C135F	17:7675208-7675208	17
42	COSM10645	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.527G>T	p.C176F	17:7675085-7675085	17
43	COSM46185	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.775G>C	p.D259H	17:7674188-7674188	17
44	COSM43689	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.482C>T	p.A161V	17:7675130-7675130	17
45	COSM10771	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.749C>T	p.P250L	17:7674214-7674214	17
46	COSM10935	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.722C>A	p.S241Y	17:7674241-7674241	17
47	COSM10758	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.659A>G	p.Y220C	17:7674872-7674872	17
48	COSM11166	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.406C>T	p.Q136*	17:7675206-7675206	17
49	COSM119021	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.993+1G>C	p.?	17:7673534-7673534	17
50	COSM43947	TP53	vulva,NS,carcinoma,squamous cell carcinoma	c.614A>G	p.Y205C	17:7674917-7674917	17

Sources

Expression for Vulva Squamous Cell Carcinoma

Search GEO for disease gene expression data for Vulva Squamous Cell Carcinoma.

Sources

Pathways for Vulva Squamous Cell Carcinoma

Pathways related to Vulva Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Photodynamic therapy-induced AP-1 survival signaling. ¹	11.03	CDKN2A TP53
2	Oncogene Induced Senescence ⁶⁶	10.76	CDKN2A TP53
3	Inhibition of Ribosome Biogenesis by p14(ARF) ⁶⁴	10.5	CDKN2A TP53
4	TP53 Network ¹ Show member pathways Activation, translocation and oligomerization of BAX ⁶⁶	10.3	CDKN2A TP53
5	LncRNA-mediated mechanisms of therapeutic resistance ¹	9.7	MEG3 TP53

Sources

GO Terms for Vulva Squamous Cell Carcinoma

Biological processes related to Vulva Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	replicative senescence	GO:0090399	8.62	CDKN2A TP53

Molecular functions related to Vulva Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	disordered domain specific binding	GO:0097718	8.62	CDKN2A TP53

Sources

Sources for Vulva Squamous Cell Carcinoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia