MCID: VLV050
MIFTS: 24

Vulvar Adenocarcinoma

Categories: Reproductive diseases, Rare diseases, Cancer diseases

Aliases & Classifications for Vulvar Adenocarcinoma

MalaCards integrated aliases for Vulvar Adenocarcinoma:

Name: Vulvar Adenocarcinoma 59 73
Adenocarcinoma of the Vulva 59

Classifications:



External Ids:

Orphanet 59 ORPHA494454

Summaries for Vulvar Adenocarcinoma

MalaCards based summary : Vulvar Adenocarcinoma, also known as adenocarcinoma of the vulva, is related to adenocarcinoma and vulva adenocarcinoma. An important gene associated with Vulvar Adenocarcinoma is RB1 (RB Transcriptional Corepressor 1), and among its related pathways/superpathways are TNFR1 Pathway and Glioma. The drug Cisplatin has been mentioned in the context of this disorder.

Related Diseases for Vulvar Adenocarcinoma

Graphical network of the top 20 diseases related to Vulvar Adenocarcinoma:



Diseases related to Vulvar Adenocarcinoma

Symptoms & Phenotypes for Vulvar Adenocarcinoma

Drugs & Therapeutics for Vulvar Adenocarcinoma

Drugs for Vulvar Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 1 15663-27-1 84093 441203 2767

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vulvar Cancer Suspended NCT02595879 Phase 1 Cisplatin;Triapine

Search NIH Clinical Center for Vulvar Adenocarcinoma

Genetic Tests for Vulvar Adenocarcinoma

Anatomical Context for Vulvar Adenocarcinoma

Publications for Vulvar Adenocarcinoma

Articles related to Vulvar Adenocarcinoma:

(show all 11)
# Title Authors Year
1
Vulvar Adenocarcinoma With Neuroendocrine Differentiation: A Case Report. ( 28157827 )
2017
2
FDG-PET/CT of Vulvar Adenocarcinoma With Diffuse Metastases. ( 27187733 )
2016
3
Vulvar adenocarcinoma: visual resemblance to a vulvar abscess. ( 23761517 )
2013
4
An unexpected complete remission of advanced intestinal-type vulvar adenocarcinoma after neoadjuvant chemotherapy: a case report and a literature review. ( 24307962 )
2013
5
Skull metastasis in primary vulvar adenocarcinoma of the Bartholin's gland: a case report. ( 15936060 )
2005
6
Liposomal doxorubicin for treatment of metastatic chemorefractory vulvar adenocarcinoma. ( 12468332 )
2002
7
Primary vulvar adenocarcinoma of cloacogenic origin. ( 11531187 )
2001
8
Radiotherapy with concurrent chemotherapy for vulvar adenocarcinoma associated with extramammary Paget's disease. ( 11161871 )
2001
9
Paget's disease of the vulva: prevalence of associated vulvar adenocarcinoma, invasive Paget's disease, and recurrence after surgical excision. ( 9914572 )
1999
10
Cutaneous metastasis from vulvar adenocarcinoma. ( 8002143 )
1994
11
Vulvar adenocarcinoma of apocrine gland (Paget's disease of the vulva). Report of a patient. ( 14426499 )
1960

Variations for Vulvar Adenocarcinoma

Expression for Vulvar Adenocarcinoma

Search GEO for disease gene expression data for Vulvar Adenocarcinoma.

Pathways for Vulvar Adenocarcinoma

Pathways related to Vulvar Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 32)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.44 RB1 TP53
2
Show member pathways
12.32 RB1 TP53
3
Show member pathways
12.31 RB1 TP53
4
Show member pathways
12.25 RB1 TP53
5
Show member pathways
12.24 RB1 TP53
6
Show member pathways
12.15 RB1 TP53
7
Show member pathways
12.14 RB1 TP53
8
Show member pathways
12.1 RB1 TP53
9 12.08 RB1 TP53
10 12.01 RB1 TP53
11
Show member pathways
11.97 RB1 TP53
12 11.95 RB1 TP53
13
Show member pathways
11.93 RB1 TP53
14
Show member pathways
11.92 RB1 TP53
15 11.87 RB1 TP53
16 11.86 RB1 TP53
17
Show member pathways
11.82 RB1 TP53
18 11.73 RB1 TP53
19 11.7 RB1 TP53
20 11.62 RB1 TP53
21 11.62 RB1 TP53
22
Show member pathways
11.56 RB1 TP53
23 11.56 RB1 TP53
24 11.5 RB1 TP53
25 11.46 RB1 TP53
26 11.37 RB1 TP53
27 11.31 RB1 TP53
28
Show member pathways
11.24 RB1 TP53
29 11.12 RB1 TP53
30 10.86 RB1 TP53
31 10.62 RB1 TP53
32 9.97 RB1 TP53

GO Terms for Vulvar Adenocarcinoma

Cellular components related to Vulvar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 PML body GO:0016605 8.62 RB1 TP53

Biological processes related to Vulvar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.26 RB1 TP53
2 negative regulation of cell proliferation GO:0008285 9.16 RB1 TP53
3 cell cycle arrest GO:0007050 8.96 RB1 TP53
4 Ras protein signal transduction GO:0007265 8.62 RB1 TP53

Molecular functions related to Vulvar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.26 RB1 TP53
2 transcription factor binding GO:0008134 9.16 RB1 TP53
3 ubiquitin protein ligase binding GO:0031625 8.96 RB1 TP53
4 disordered domain specific binding GO:0097718 8.62 RB1 TP53

Sources for Vulvar Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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