MCID: VLV016
MIFTS: 23

Vulvar Apocrine Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulvar Apocrine Adenocarcinoma

MalaCards integrated aliases for Vulvar Apocrine Adenocarcinoma:

Name: Vulvar Apocrine Adenocarcinoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:6448
NCIt 49 C40308
UMLS 71 C2202741

Summaries for Vulvar Apocrine Adenocarcinoma

Disease Ontology : 12 A vulva adenocarcinoma that has material basis in apocrine glands.

MalaCards based summary : Vulvar Apocrine Adenocarcinoma is related to mammary paget's disease and apocrine adenocarcinoma. An important gene associated with Vulvar Apocrine Adenocarcinoma is PIP (Prolactin Induced Protein), and among its related pathways/superpathways are Developmental Biology and Cytoskeletal Signaling. Related phenotype is digestive/alimentary.

Related Diseases for Vulvar Apocrine Adenocarcinoma

Diseases related to Vulvar Apocrine Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 323)
# Related Disease Score Top Affiliating Genes
1 mammary paget's disease 30.2 PIP KRT7 KRT20
2 apocrine adenocarcinoma 29.5 PIP KRT7 KRT5 AR
3 nipples, supernumerary 10.4 PIP KRT20
4 villous adenoma 10.4 KRT20 CEACAM5
5 glycogen-rich clear cell breast carcinoma 10.4 PIP KRT20
6 vulvar syringoma 10.4 PIP CEACAM5
7 vulvar eccrine porocarcinoma 10.4 PIP CEACAM5
8 nodular hidradenoma 10.4 PIP CEACAM5
9 fox-fordyce disease 10.4 PIP CEACAM5
10 eccrine papillary adenoma 10.4 PIP CEACAM5
11 mucoepidermoid esophageal carcinoma 10.3 KRT5 CEACAM5
12 breast cystic hypersecretory carcinoma 10.3 KRT5 CEACAM5
13 malignant acrospiroma 10.3 KRT5 CEACAM5
14 gallbladder squamous cell carcinoma 10.3 KRT5 CEACAM5
15 malignant epithelial mesothelioma 10.3 KRT5 CEACAM5
16 vulva basal cell carcinoma 10.3 KRT5 CEACAM5
17 lipid-rich carcinoma 10.3 PIP KRT5
18 vulvar benign neoplasm 10.3 PIP CEACAM5
19 anal canal paget's disease 10.3 PIP KRT7
20 anal gland adenocarcinoma 10.3 PIP KRT7
21 bartholin's gland adenocarcinoma 10.3 PIP KRT7
22 bartholin's gland carcinoma 10.3 PIP KRT7
23 ovarian cystadenoma 10.3 KRT7 CEACAM5
24 pancreatic serous cystadenocarcinoma 10.3 KRT7 KRT20
25 bartholin's gland disease 10.3 PIP KRT7
26 nephrogenic adenoma of urinary bladder 10.3 KRT7 KRT20
27 ovarian large-cell neuroendocrine carcinoma 10.2 KRT7 KRT20
28 atrophic vulva 10.2 KRT7 KRT20
29 cystitis cystica 10.2 KRT7 KRT20
30 signet ring basal cell carcinoma 10.2 PTPRC CEACAM5
31 cutaneous mucoepidermoid carcinoma 10.2 KRT7 CEACAM5
32 pancreatic foamy gland adenocarcinoma 10.2 KRT7 CEACAM5
33 jejunal cancer 10.2 KRT7 KRT20
34 mucinous adenofibroma 10.2 KRT7 CEACAM5
35 intratubular embryonal carcinoma 10.2 KRT7 KRT20
36 pancreas lymphoma 10.2 PTPRC CEACAM5
37 sigmoid neoplasm 10.2 KRT7 CEACAM5
38 papillary transitional carcinoma 10.2 KRT7 KRT20
39 ovarian brenner tumor 10.2 KRT7 KRT20
40 odontoma 10.2 KRT5 KRT19
41 mucinous intrahepatic cholangiocarcinoma 10.2 KRT7 CEACAM5
42 inverted transitional papilloma 10.2 KRT7 KRT5
43 intracystic papillary adenoma 10.2 KRT5 CEACAM5
44 appendiceal neoplasm 10.2 KRT7 CEACAM5
45 glandular cystitis 10.2 KRT7 KRT20
46 benign breast adenomyoepithelioma 10.2 KRT7 KRT5
47 breast adenomyoepithelioma 10.2 KRT7 KRT5
48 subareolar duct papillomatosis 10.2 KRT7 KRT5
49 biliary papillomatosis 10.2 KRT7 CEACAM5
50 pericardial mesothelioma 10.2 KRT5 KRT19

Graphical network of the top 20 diseases related to Vulvar Apocrine Adenocarcinoma:



Diseases related to Vulvar Apocrine Adenocarcinoma

Symptoms & Phenotypes for Vulvar Apocrine Adenocarcinoma

MGI Mouse Phenotypes related to Vulvar Apocrine Adenocarcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 AR KRT19 KRT5 PIP PTPRC

Drugs & Therapeutics for Vulvar Apocrine Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Vulvar Apocrine Adenocarcinoma

Genetic Tests for Vulvar Apocrine Adenocarcinoma

Anatomical Context for Vulvar Apocrine Adenocarcinoma

Publications for Vulvar Apocrine Adenocarcinoma

Articles related to Vulvar Apocrine Adenocarcinoma:

# Title Authors PMID Year
1
[Use of Vacuum-Assisted Closure Therapy in the Treatment of Postoperative Inguinal Lymphocele after Lymphadenectomy for a Vulvar Apocrine Adenocarcinoma : A Case Report]. 61
31501398 2019
2
Apocrine Adenocarcinoma of the Vulva: A Case Report and Review of the Literature. 61
27668109 2016
3
Clinicopathologic characteristics of 12 patients with vulvar sweat gland carcinoma. 61
20606537 2010
4
Vulvar apocrine adenocarcinoma: a case with nodal metastasis and intranodal mucinous differentiation. 61
18842349 2009

Variations for Vulvar Apocrine Adenocarcinoma

Expression for Vulvar Apocrine Adenocarcinoma

Search GEO for disease gene expression data for Vulvar Apocrine Adenocarcinoma.

Pathways for Vulvar Apocrine Adenocarcinoma

Pathways related to Vulvar Apocrine Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.87 PTPRC KRT7 KRT5 KRT20 KRT19
2 11.75 KRT7 KRT5 KRT20 KRT19
3
Show member pathways
11.38 KRT7 KRT5 KRT20 KRT19
4
Show member pathways
11.37 KRT7 KRT5 KRT19

GO Terms for Vulvar Apocrine Adenocarcinoma

Cellular components related to Vulvar Apocrine Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.5 PTPRC PIP KRT7 KRT5 KRT19 ENO2
2 intermediate filament GO:0005882 8.92 KRT7 KRT5 KRT20 KRT19

Biological processes related to Vulvar Apocrine Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.26 KRT7 KRT5 KRT20 KRT19
2 cornification GO:0070268 8.92 KRT7 KRT5 KRT20 KRT19

Molecular functions related to Vulvar Apocrine Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.8 KRT5 KRT20 KRT19

Sources for Vulvar Apocrine Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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