MCID: VLV035
MIFTS: 22

Vulvar Benign Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulvar Benign Neoplasm

MalaCards integrated aliases for Vulvar Benign Neoplasm:

Name: Vulvar Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060109

Summaries for Vulvar Benign Neoplasm

Disease Ontology : 12 A female reproductive organ benign neoplasm that is located in the vulva.

MalaCards based summary : Vulvar Benign Neoplasm is related to vulvar syringoma and vulvar leiomyoma. An important gene associated with Vulvar Benign Neoplasm is PGR (Progesterone Receptor), and among its related pathways/superpathways are Signaling by ERBB4 and Nuclear Receptor transcription pathway. Affiliated tissues include lung, ovary and prostate.

Related Diseases for Vulvar Benign Neoplasm

Diseases related to Vulvar Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
# Related Disease Score Top Affiliating Genes
1 vulvar syringoma 32.0 ESR1 PGR
2 vulvar leiomyoma 30.9 CALD1 ESR1 PGR PLAG1 SLC4A1
3 vulvar nodular hidradenoma 11.2
4 vulvar angiokeratoma 11.2
5 vulvar trichoepithelioma 11.2
6 endometrial stromal nodule 10.1 CALD1 PGR
7 leiomyoma 10.1 ESR1 PGR
8 myoma 10.1 ESR1 PGR
9 leiomyomatosis 10.1 ESR1 PGR
10 vestibular gland benign neoplasm 10.1 ESR1 PGR
11 bartholin's gland adenoma 10.1 ESR1 PGR
12 glassy cell carcinoma of the cervix 10.1 ESR1 PGR
13 lung leiomyoma 10.1 ESR1 PGR
14 trigonitis 10.1 ESR1 PGR
15 predominantly cortical thymoma 10.1 ESR1 PGR
16 breast medullary carcinoma 10.1 ESR1 PGR
17 breast scirrhous carcinoma 10.1 ESR1 PGR
18 bartholin's gland benign neoplasm 10.1 ESR1 PGR
19 oncocytic breast carcinoma 10.1 ESR1 PGR
20 progesterone-receptor positive breast cancer 10.1 ESR1 PGR
21 progesterone resistance 10.1 ESR1 PGR
22 endometrial squamous cell carcinoma 10.1 ESR1 PGR
23 cribriform carcinoma 10.1 ESR1 PGR
24 endometrial mucinous adenocarcinoma 10.1 ESR1 PGR
25 adenoid basal cell carcinoma 10.1 ESR1 PGR
26 breast adenoid cystic carcinoma 10.1 ESR1 PGR
27 apocrine adenocarcinoma 10.1 ESR1 PGR
28 gender identity disorder 10.1 ESR1 PGR
29 deep angioma 10.1 ESR1 PGR
30 synchronous bilateral breast carcinoma 10.1 ESR1 PGR
31 muscle cancer 10.1 CALD1 PGR
32 female reproductive endometrioid cancer 10.1 ESR1 PGR
33 cervical carcinosarcoma 10.1 ESR1 PGR
34 estrogen excess 10.1 ESR1 PGR
35 intramuscular hemangioma 10.1 ESR1 PGR
36 glycogen-rich clear cell breast carcinoma 10.1 ESR1 PGR
37 mammographic density 10.1 ESR1 PGR
38 cervical clear cell adenocarcinoma 10.1 ESR1 PGR
39 retinitis pigmentosa 47 10.1 ESR1 PGR
40 inflammatory breast carcinoma 10.1 ESR1 PGR
41 retinitis pigmentosa 20 10.1 ESR1 PGR
42 adenosarcoma 10.1 ESR1 PGR
43 luminal breast carcinoma 10.1 ESR1 PGR
44 endometriosis of ovary 10.1 ESR1 PGR
45 endometriosis 10.1 ESR1 PGR
46 breast myofibroblastoma 10.1 CALD1 ESR1
47 breast benign neoplasm 10.1 ESR1 PGR
48 thoracic benign neoplasm 10.0 ESR1 PGR
49 glomangiomyoma 10.0 CALD1 ESR1
50 uterine corpus cancer 10.0 ESR1 PGR

Graphical network of the top 20 diseases related to Vulvar Benign Neoplasm:



Diseases related to Vulvar Benign Neoplasm

Symptoms & Phenotypes for Vulvar Benign Neoplasm

Drugs & Therapeutics for Vulvar Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Vulvar Benign Neoplasm

Genetic Tests for Vulvar Benign Neoplasm

Anatomical Context for Vulvar Benign Neoplasm

MalaCards organs/tissues related to Vulvar Benign Neoplasm:

41
Lung, Ovary, Prostate, Cervix, Smooth Muscle

The Foundational Model of Anatomy Ontology organs/tissues related to Vulvar Benign Neoplasm:

19
The Vulva

Publications for Vulvar Benign Neoplasm

Variations for Vulvar Benign Neoplasm

Expression for Vulvar Benign Neoplasm

Search GEO for disease gene expression data for Vulvar Benign Neoplasm.

Pathways for Vulvar Benign Neoplasm

Pathways related to Vulvar Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.99 ESR1 PGR
2
Show member pathways
10.58 ESR1 PGR

GO Terms for Vulvar Benign Neoplasm

Biological processes related to Vulvar Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone mediated signaling pathway GO:0043401 9.16 ESR1 PGR
2 negative regulation of gene expression GO:0010629 9.13 ESR1 PGR PLAG1
3 transcription, DNA-templated GO:0006351 8.8 ESR1 PGR PLAG1

Molecular functions related to Vulvar Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.5 ESR1 PGR PLAG1
2 ATPase binding GO:0051117 9.37 ESR1 PGR
3 steroid hormone receptor activity GO:0003707 9.26 ESR1 PGR
4 nuclear receptor activity GO:0004879 9.16 ESR1 PGR
5 proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001077 9.13 ESR1 PGR PLAG1
6 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Vulvar Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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