MCID: VLV035
MIFTS: 22

Vulvar Benign Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulvar Benign Neoplasm

MalaCards integrated aliases for Vulvar Benign Neoplasm:

Name: Vulvar Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060109

Summaries for Vulvar Benign Neoplasm

Disease Ontology : 12 A female reproductive organ benign neoplasm that is located in the vulva.

MalaCards based summary : Vulvar Benign Neoplasm is related to vulvar syringoma and vulvar leiomyoma. An important gene associated with Vulvar Benign Neoplasm is PGR (Progesterone Receptor), and among its related pathways/superpathways are Cell cycle Role of SCF complex in cell cycle regulation and Signaling by ERBB4. Affiliated tissues include the vulva, ovary and cervix.

Related Diseases for Vulvar Benign Neoplasm

Diseases related to Vulvar Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Related Disease Score Top Affiliating Genes
1 vulvar syringoma 32.0 ESR1 PGR
2 vulvar leiomyoma 30.9 CALD1 ESR1 PGR PLAG1
3 vulvar nodular hidradenoma 11.3
4 vulvar angiokeratoma 11.3
5 vulvar trichoepithelioma 11.3
6 endometrial stromal nodule 10.1 CALD1 PGR
7 leiomyoma 10.1 ESR1 PGR
8 myoma 10.1 ESR1 PGR
9 leiomyomatosis 10.1 ESR1 PGR
10 vestibular gland benign neoplasm 10.1 ESR1 PGR
11 bartholin's gland adenoma 10.1 ESR1 PGR
12 lung leiomyoma 10.1 ESR1 PGR
13 glassy cell carcinoma of the cervix 10.1 ESR1 PGR
14 breast myofibroblastoma 10.1 CALD1 ESR1
15 trigonitis 10.1 ESR1 PGR
16 predominantly cortical thymoma 10.1 ESR1 PGR
17 glomangiomyoma 10.1 CALD1 ESR1
18 breast medullary carcinoma 10.1 ESR1 PGR
19 breast scirrhous carcinoma 10.1 ESR1 PGR
20 bartholin's gland benign neoplasm 10.1 ESR1 PGR
21 oncocytic breast carcinoma 10.1 ESR1 PGR
22 progesterone-receptor positive breast cancer 10.1 ESR1 PGR
23 progesterone resistance 10.1 ESR1 PGR
24 endometrial squamous cell carcinoma 10.1 ESR1 PGR
25 cribriform carcinoma 10.1 ESR1 PGR
26 endometrial mucinous adenocarcinoma 10.1 ESR1 PGR
27 adenoid basal cell carcinoma 10.1 ESR1 PGR
28 apocrine adenocarcinoma 10.1 ESR1 PGR
29 gender identity disorder 10.1 ESR1 PGR
30 deep angioma 10.1 ESR1 PGR
31 muscle cancer 10.1 CALD1 PGR
32 synchronous bilateral breast carcinoma 10.1 ESR1 PGR
33 breast adenoid cystic carcinoma 10.1 ESR1 PGR
34 female reproductive endometrioid cancer 10.1 ESR1 PGR
35 cervical carcinosarcoma 10.1 ESR1 PGR
36 estrogen excess 10.1 ESR1 PGR
37 intramuscular hemangioma 10.1 ESR1 PGR
38 glycogen-rich clear cell breast carcinoma 10.1 ESR1 PGR
39 mammographic density 10.1 ESR1 PGR
40 cervical clear cell adenocarcinoma 10.1 ESR1 PGR
41 retinitis pigmentosa 47 10.1 ESR1 PGR
42 inflammatory breast carcinoma 10.1 ESR1 PGR
43 retinitis pigmentosa 20 10.0 ESR1 PGR
44 adenosarcoma 10.0 ESR1 PGR
45 luminal breast carcinoma 10.0 ESR1 PGR
46 endometriosis of ovary 10.0 ESR1 PGR
47 endometriosis 10.0 ESR1 PGR
48 breast benign neoplasm 10.0 ESR1 PGR
49 thoracic benign neoplasm 10.0 ESR1 PGR
50 uterine corpus cancer 10.0 ESR1 PGR

Graphical network of the top 20 diseases related to Vulvar Benign Neoplasm:



Diseases related to Vulvar Benign Neoplasm

Symptoms & Phenotypes for Vulvar Benign Neoplasm

Drugs & Therapeutics for Vulvar Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Vulvar Benign Neoplasm

Genetic Tests for Vulvar Benign Neoplasm

Anatomical Context for Vulvar Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Vulvar Benign Neoplasm:

20
The Vulva

MalaCards organs/tissues related to Vulvar Benign Neoplasm:

42
Ovary, Cervix, Smooth Muscle

Publications for Vulvar Benign Neoplasm

Variations for Vulvar Benign Neoplasm

Expression for Vulvar Benign Neoplasm

Search GEO for disease gene expression data for Vulvar Benign Neoplasm.

Pathways for Vulvar Benign Neoplasm

Pathways related to Vulvar Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.4 ESR1 PGR
2
Show member pathways
10.99 ESR1 PGR
3
Show member pathways
10.58 ESR1 PGR

GO Terms for Vulvar Benign Neoplasm

Biological processes related to Vulvar Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription initiation from RNA polymerase II promoter GO:0006367 9.26 ESR1 PGR
2 steroid hormone mediated signaling pathway GO:0043401 9.16 ESR1 PGR
3 negative regulation of gene expression GO:0010629 9.13 ESR1 PGR PLAG1
4 transcription, DNA-templated GO:0006351 8.62 ESR1 PLAG1

Molecular functions related to Vulvar Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription factor activity GO:0003700 9.54 ESR1 PGR PLAG1
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.43 ESR1 PGR PLAG1
3 ATPase binding GO:0051117 9.32 ESR1 PGR
4 steroid hormone receptor activity GO:0003707 9.16 ESR1 PGR
5 nuclear receptor activity GO:0004879 8.96 ESR1 PGR
6 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Vulvar Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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