MCID: VLV035
MIFTS: 22

Vulvar Benign Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulvar Benign Neoplasm

MalaCards integrated aliases for Vulvar Benign Neoplasm:

Name: Vulvar Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060109

Summaries for Vulvar Benign Neoplasm

Disease Ontology : 12 A female reproductive organ benign neoplasm that is located in the vulva.

MalaCards based summary : Vulvar Benign Neoplasm is related to vulvar angiokeratoma and vulvar syringoma. An important gene associated with Vulvar Benign Neoplasm is PLAG1 (PLAG1 Zinc Finger), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include vulva, breast and colon, and related phenotypes are hematopoietic system and immune system

Related Diseases for Vulvar Benign Neoplasm

Diseases related to Vulvar Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 270)
# Related Disease Score Top Affiliating Genes
1 vulvar angiokeratoma 32.1 SERPINC1 NDUFA2 HP ENPP3
2 vulvar syringoma 30.8 PIP PGR ESR1 CEACAM5 CD2AP
3 vulvar leiomyoma 29.6 RB1CC1 PLAG1 PGR PECAM1 OCM NCAM1
4 vulvar nodular hidradenoma 11.4
5 vulvar trichoepithelioma 11.4
6 vulvar granular cell tumor 11.4
7 peritoneal benign neoplasm 10.5 PGR CALD1
8 glassy cell carcinoma of the cervix 10.5 PGR ESR1
9 bartholin's gland adenoid cystic carcinoma 10.5 PGR ESR1
10 chronic tympanitis 10.5 PGR ESR1
11 bartholin's gland adenoma 10.5 PGR ESR1
12 bartholin's gland benign neoplasm 10.5 PGR ESR1
13 vestibular gland benign neoplasm 10.5 PGR ESR1
14 breast juvenile papillomatosis 10.5 PGR ESR1
15 trigonitis 10.5 PGR ESR1
16 breast scirrhous carcinoma 10.5 PGR ESR1
17 acanthoma 10.5 OCM CLEC2A
18 myxoid leiomyosarcoma 10.5 PLAG1 PGR
19 salivary gland adenoma, pleomorphic 10.5 PLAG1 HMGA2
20 ovarian seromucinous carcinoma 10.5 PGR ESR1
21 breast papillary carcinoma 10.5 PGR ESR1
22 cervical adenoma malignum 10.5 HMGA2 CALD1
23 comedo carcinoma 10.5 PGR ESR1
24 breast metaplastic carcinoma 10.5 PGR ESR1
25 chondroid lipoma 10.5 PLAG1 HMGA2
26 mammographic density 10.4 PGR ESR1
27 pleomorphic adenoma carcinoma 10.4 PLAG1 HMGA2
28 lung combined type small cell carcinoma 10.4 NCAM1 CALD1
29 lung leiomyoma 10.4 PGR ESR1 CALD1
30 vagina leiomyosarcoma 10.4 PGR ESR1 CALD1
31 intravenous leiomyomatosis 10.4 PGR ESR1 CALD1
32 endosalpingiosis 10.4 PGR ESR1
33 adenomyoma 10.4 PGR ESR1 CALD1
34 progesterone-receptor negative breast cancer 10.4 PGR ESR1
35 vaginal cancer 10.4 PGR ESR1 CALD1
36 progesterone resistance 10.3 PGR ESR1
37 glycogen-rich clear cell breast carcinoma 10.3 PIP PGR
38 gender identity disorder 10.3 PGR ESR1
39 bartholin's gland disease 10.3 PIP PGR
40 transitional meningioma 10.3 PGR NCAM1
41 endometritis 10.3 PGR HP ESR1
42 glomangiomyoma 10.3 CD34 CALD1
43 breast mucinous carcinoma 10.3 PIP PGR
44 glomangiosarcoma 10.3 CD34 CALD1
45 nephrogenic adenofibroma 10.3 CD34 CALD1
46 breast osteosarcoma 10.3 PGR ESR1
47 pacinian tumor 10.3 CLEC2A CD34
48 deep leiomyoma 10.3 CD34 CALD1
49 endometrial disease 10.3 PGR HP ESR1
50 vulvar sarcoma 10.3 PLAG1 CD34

Graphical network of the top 20 diseases related to Vulvar Benign Neoplasm:



Diseases related to Vulvar Benign Neoplasm

Symptoms & Phenotypes for Vulvar Benign Neoplasm

MGI Mouse Phenotypes related to Vulvar Benign Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.65 CD2AP CD34 ENPP3 ESR1 HP PECAM1
2 immune system MP:0005387 9.32 CD2AP CD34 ENPP3 ESR1 HP PECAM1

Drugs & Therapeutics for Vulvar Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Vulvar Benign Neoplasm

Genetic Tests for Vulvar Benign Neoplasm

Anatomical Context for Vulvar Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Vulvar Benign Neoplasm:

19
Vulva

MalaCards organs/tissues related to Vulvar Benign Neoplasm:

40
Breast, Colon, Heart, Lung, Skin, Liver, Ovary

Publications for Vulvar Benign Neoplasm

Variations for Vulvar Benign Neoplasm

Expression for Vulvar Benign Neoplasm

Search GEO for disease gene expression data for Vulvar Benign Neoplasm.

Pathways for Vulvar Benign Neoplasm

Pathways related to Vulvar Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.61 PECAM1 NCAM1 ENPP3 CEACAM5 CD34 CD2AP
2 11.2 NCAM1 CEACAM5 CD34

GO Terms for Vulvar Benign Neoplasm

Biological processes related to Vulvar Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.46 PLAG1 PGR ESR1 CD34
2 paracrine signaling GO:0038001 8.96 PGR CD34
3 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Sources for Vulvar Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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