MCID: VLV015
MIFTS: 23

Vulvar Dystrophy

Categories: Reproductive diseases

Aliases & Classifications for Vulvar Dystrophy

MalaCards integrated aliases for Vulvar Dystrophy:

Name: Vulvar Dystrophy 12 15
Dystrophy of Vulva 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:14292
ICD9CM 36 624.0
NCIt 51 C34565
SNOMED-CT 69 51689003
ICD10 34 N90.4
UMLS 74 C0013426

Summaries for Vulvar Dystrophy

Disease Ontology : 12 A vulvar disease that is characterized as irregular patchy areas of thickened skin and severe itching.

MalaCards based summary : Vulvar Dystrophy, also known as dystrophy of vulva, is related to squamous cell carcinoma and prostate stromal sarcoma. An important gene associated with Vulvar Dystrophy is PGR (Progesterone Receptor), and among its related pathways/superpathways is Cell cycle Role of SCF complex in cell cycle regulation. Affiliated tissues include skin, cervix and t cells.

Related Diseases for Vulvar Dystrophy

Diseases related to Vulvar Dystrophy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 52)
# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 10.2
2 prostate stromal sarcoma 10.1 CD34 PGR
3 trigonitis 10.1 CD34 PGR
4 lung meningioma 10.1 CD34 PGR
5 leiomyoma 10.1 CD34 PGR
6 peritoneal benign neoplasm 10.1 CD34 PGR
7 deep angioma 10.1 CD34 PGR
8 diffuse peritoneal leiomyomatosis 10.1 CD34 PGR
9 intramuscular hemangioma 10.1 CD34 PGR
10 breast benign neoplasm 10.1 CD34 PGR
11 thoracic benign neoplasm 10.1 CD34 PGR
12 congenital epulis 10.1 CD34 PGR
13 bartholin's gland benign neoplasm 10.1 CDKN2A PGR
14 bizarre leiomyoma 10.1 CDKN2A PGR
15 endometrial squamous cell carcinoma 10.1 CDKN2A PGR
16 endometrial mucinous adenocarcinoma 10.1 CDKN2A PGR
17 adenoid basal cell carcinoma 10.1 CDKN2A PGR
18 bartholin's gland disease 10.1 CDKN2A PGR
19 spindle cell synovial sarcoma 10.1 CD34 MBP
20 muscle cancer 10.1 CD34 PGR
21 glycogen-rich clear cell breast carcinoma 10.1 CDKN2A PGR
22 pre-malignant neoplasm 10.0 CDKN2A PGR
23 atypical neurofibroma 10.0 CD34 CDKN2A
24 squamous cell papilloma 10.0
25 papilloma 10.0
26 lichen sclerosus 10.0
27 neurofibroma 10.0 CD34 CDKN2A
28 ischemic fasciitis 10.0 CD34 CDKN2A
29 in situ carcinoma 10.0 CDKN2A PGR
30 cervical adenocarcinoma 10.0 CDKN2A PGR
31 juvenile pilocytic astrocytoma 10.0 CDKN2A MBP
32 uterine anomalies 10.0 CDKN2A PGR
33 cellular schwannoma 10.0 CD34 CDKN2A
34 female reproductive system disease 10.0 CDKN2A PGR
35 reproductive system disease 9.9 CDKN2A PGR
36 cell type benign neoplasm 9.9 CD34 CDKN2A
37 liposarcoma 9.9 CD34 CDKN2A
38 endometrial adenocarcinoma 9.9 CDKN2A PGR
39 nervous system cancer 9.9 CD34 CDKN2A
40 vulval paget's disease 9.9 CDKN2A LINC01191
41 gastrointestinal system cancer 9.9 CD34 CDKN2A
42 vulvar disease 9.9 CDKN2A LINC01191
43 vulva adenocarcinoma 9.8 CDKN2A LINC01191
44 penile disease 9.8 CDKN2A LINC01191
45 precursor t-cell acute lymphoblastic leukemia 9.8 CD34 CDKN2A
46 anus disease 9.8 CDKN2A LINC01191
47 vulva cancer 9.8 CDKN2A LINC01191
48 rectal disease 9.8 CDKN2A LINC01191
49 oligodendroglioma 9.8 CDKN2A MBP
50 meningioma, familial 9.8 CD34 CDKN2A PGR

Comorbidity relations with Vulvar Dystrophy via Phenotypic Disease Network (PDN):


Vulva Cancer

Graphical network of the top 20 diseases related to Vulvar Dystrophy:



Diseases related to Vulvar Dystrophy

Symptoms & Phenotypes for Vulvar Dystrophy

Drugs & Therapeutics for Vulvar Dystrophy

Search Clinical Trials , NIH Clinical Center for Vulvar Dystrophy

Genetic Tests for Vulvar Dystrophy

Anatomical Context for Vulvar Dystrophy

MalaCards organs/tissues related to Vulvar Dystrophy:

42
Skin, Cervix, T Cells

Publications for Vulvar Dystrophy

Articles related to Vulvar Dystrophy:

(show all 16)
# Title Authors Year
1
The effect of hyaluronic acid (Cicatridine) on healing and regeneration of the uterine cervix and vagina and vulvar dystrophy therapy. ( 21446328 )
2011
2
In defense of Jeffcoate and Woodcock and their "vulvar dystrophy" terminology: the 2006 ISSVD presidential address. ( 17286060 )
2007
3
[Relationship between vulvar dystrophy, malignant tumor and the estrogen progestin receptor]. ( 12515151 )
2000
4
Clinical observation on electrothermal acupuncture in treatment of 16 cases of vulvar dystrophy. ( 10921135 )
1999
5
Vulvar dystrophy: an evaluation of 285 cases. ( 9105866 )
1997
6
Squamous cell carcinoma of the vulva in association with mixed vulvar dystrophy. A brief report with review of literature. ( 9491669 )
1997
7
Human papilloma virus, vulvar dystrophy, and vulvar carcinoma: differential expression of human papillomavirus and vulvar dystrophy in the presence and absence of squamous cell carcinoma of the vulva. ( 8641610 )
1996
8
Vulvar dystrophy: a clinical follow-up. ( 1449423 )
1992
9
Malignant potential of mixed vulvar dystrophy (lichen sclerosus associated with squamous cell hyperplasia). ( 3404517 )
1988
10
Vulvar dystrophy. ( 3987128 )
1985
11
Squamous cell carcinoma of the vulva in association with mixed vulvar dystrophy in an 18-year-old girl. Case report. ( 6691950 )
1984
12
Androgen, estrogen and progesterone receptors in vulvar dystrophy. ( 6671316 )
1983
13
Familial vulvar dystrophy of lichen sclerosus type. ( 7082025 )
1982
14
Topical progesterone in treatment of vulvar dystrophy: preliminary report of five cases. ( 842596 )
1977
15
Histochemical investigations on vulvar dystrophy. ( 4669390 )
1972
16
Topical testosterone for benign vulvar dystrophy. ( 4933358 )
1971

Variations for Vulvar Dystrophy

Expression for Vulvar Dystrophy

Search GEO for disease gene expression data for Vulvar Dystrophy.

Pathways for Vulvar Dystrophy

Pathways related to Vulvar Dystrophy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.87 CDKN2A PGR

GO Terms for Vulvar Dystrophy

Cellular components related to Vulvar Dystrophy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 CD34 MBP

Biological processes related to Vulvar Dystrophy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 paracrine signaling GO:0038001 8.62 CD34 PGR

Sources for Vulvar Dystrophy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....