MCID: VLV015
MIFTS: 24

Vulvar Dystrophy

Categories: Reproductive diseases

Aliases & Classifications for Vulvar Dystrophy

MalaCards integrated aliases for Vulvar Dystrophy:

Name: Vulvar Dystrophy 12 15
Dystrophy of Vulva 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:14292
ICD10 33 N90.4
ICD9CM 35 624.0
NCIt 50 C34565
SNOMED-CT 68 51689003
UMLS 73 C0013426

Summaries for Vulvar Dystrophy

Disease Ontology : 12 A vulvar disease that is characterized as irregular patchy areas of thickened skin and severe itching.

MalaCards based summary : Vulvar Dystrophy, also known as dystrophy of vulva, is related to squamous cell carcinoma and prostate stromal sarcoma. An important gene associated with Vulvar Dystrophy is PGR (Progesterone Receptor), and among its related pathways/superpathways is Cell cycle Role of SCF complex in cell cycle regulation. Affiliated tissues include skin, cervix and lung.

Related Diseases for Vulvar Dystrophy

Diseases related to Vulvar Dystrophy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 10.2
2 prostate stromal sarcoma 10.1 CD34 PGR
3 trigonitis 10.1 CD34 PGR
4 lung meningioma 10.1 CD34 PGR
5 leiomyoma 10.1 CD34 PGR
6 peritoneal benign neoplasm 10.1 CD34 PGR
7 deep angioma 10.1 CD34 PGR
8 diffuse peritoneal leiomyomatosis 10.1 CD34 PGR
9 intramuscular hemangioma 10.1 CD34 PGR
10 breast benign neoplasm 10.1 CD34 PGR
11 thoracic benign neoplasm 10.1 CD34 PGR
12 congenital epulis 10.1 CD34 PGR
13 bartholin's gland benign neoplasm 10.1 CDKN2A PGR
14 bizarre leiomyoma 10.1 CDKN2A PGR
15 endometrial squamous cell carcinoma 10.1 CDKN2A PGR
16 endometrial mucinous adenocarcinoma 10.0 CDKN2A PGR
17 adenoid basal cell carcinoma 10.0 CDKN2A PGR
18 bartholin's gland disease 10.0 CDKN2A PGR
19 spindle cell synovial sarcoma 10.0 CD34 MBP
20 muscle cancer 10.0 CD34 PGR
21 glycogen-rich clear cell breast carcinoma 10.0 CDKN2A PGR
22 pre-malignant neoplasm 10.0 CDKN2A PGR
23 atypical neurofibroma 10.0 CD34 CDKN2A
24 neurofibroma 10.0 CD34 CDKN2A
25 ischemic fasciitis 10.0 CD34 CDKN2A
26 papilloma 10.0
27 lichen sclerosus 10.0
28 in situ carcinoma 10.0 CDKN2A PGR
29 cervical adenocarcinoma 10.0 CDKN2A PGR
30 juvenile pilocytic astrocytoma 10.0 CDKN2A MBP
31 uterine anomalies 10.0 CDKN2A PGR
32 cellular schwannoma 10.0 CD34 CDKN2A
33 female reproductive system disease 10.0 CDKN2A PGR
34 reproductive system disease 10.0 CDKN2A PGR
35 cell type benign neoplasm 10.0 CD34 CDKN2A
36 endometrial adenocarcinoma 10.0 CDKN2A PGR
37 liposarcoma 10.0 CD34 CDKN2A
38 nervous system cancer 9.9 CD34 CDKN2A
39 vulval paget's disease 9.9 CDKN2A LINC01191
40 precursor t-cell acute lymphoblastic leukemia 9.9 CD34 CDKN2A
41 vulvar disease 9.9 CDKN2A LINC01191
42 vulva adenocarcinoma 9.9 CDKN2A LINC01191
43 penile disease 9.9 CDKN2A LINC01191
44 gastrointestinal system cancer 9.9 CD34 CDKN2A
45 anus disease 9.9 CDKN2A LINC01191
46 vulva cancer 9.9 CDKN2A LINC01191
47 rectal disease 9.9 CDKN2A LINC01191
48 oligodendroglioma 9.9 CDKN2A MBP
49 meningioma, familial 9.9 CD34 CDKN2A PGR
50 gastrointestinal stromal tumor 9.8 CD34 CDKN2A

Comorbidity relations with Vulvar Dystrophy via Phenotypic Disease Network (PDN):


Vulva Cancer

Graphical network of the top 20 diseases related to Vulvar Dystrophy:



Diseases related to Vulvar Dystrophy

Symptoms & Phenotypes for Vulvar Dystrophy

Drugs & Therapeutics for Vulvar Dystrophy

Search Clinical Trials , NIH Clinical Center for Vulvar Dystrophy

Genetic Tests for Vulvar Dystrophy

Anatomical Context for Vulvar Dystrophy

MalaCards organs/tissues related to Vulvar Dystrophy:

41
Skin, Cervix, Lung, Prostate, T Cells

Publications for Vulvar Dystrophy

Articles related to Vulvar Dystrophy:

(show all 16)
# Title Authors Year
1
The effect of hyaluronic acid (Cicatridine) on healing and regeneration of the uterine cervix and vagina and vulvar dystrophy therapy. ( 21446328 )
2011
2
In defense of Jeffcoate and Woodcock and their "vulvar dystrophy" terminology: the 2006 ISSVD presidential address. ( 17286060 )
2007
3
[Relationship between vulvar dystrophy, malignant tumor and the estrogen progestin receptor]. ( 12515151 )
2000
4
Clinical observation on electrothermal acupuncture in treatment of 16 cases of vulvar dystrophy. ( 10921135 )
1999
5
Squamous cell carcinoma of the vulva in association with mixed vulvar dystrophy. A brief report with review of literature. ( 9491669 )
1997
6
Vulvar dystrophy: an evaluation of 285 cases. ( 9105866 )
1997
7
Human papilloma virus, vulvar dystrophy, and vulvar carcinoma: differential expression of human papillomavirus and vulvar dystrophy in the presence and absence of squamous cell carcinoma of the vulva. ( 8641610 )
1996
8
Vulvar dystrophy: a clinical follow-up. ( 1449423 )
1992
9
Malignant potential of mixed vulvar dystrophy (lichen sclerosus associated with squamous cell hyperplasia). ( 3404517 )
1988
10
Vulvar dystrophy. ( 3987128 )
1985
11
Squamous cell carcinoma of the vulva in association with mixed vulvar dystrophy in an 18-year-old girl. Case report. ( 6691950 )
1984
12
Androgen, estrogen and progesterone receptors in vulvar dystrophy. ( 6671316 )
1983
13
Familial vulvar dystrophy of lichen sclerosus type. ( 7082025 )
1982
14
Topical progesterone in treatment of vulvar dystrophy: preliminary report of five cases. ( 842596 )
1977
15
Histochemical investigations on vulvar dystrophy. ( 4669390 )
1972
16
Topical testosterone for benign vulvar dystrophy. ( 4933358 )
1971

Variations for Vulvar Dystrophy

Expression for Vulvar Dystrophy

Search GEO for disease gene expression data for Vulvar Dystrophy.

Pathways for Vulvar Dystrophy

Pathways related to Vulvar Dystrophy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.87 CDKN2A PGR

GO Terms for Vulvar Dystrophy

Cellular components related to Vulvar Dystrophy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 CD34 MBP

Biological processes related to Vulvar Dystrophy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 paracrine signaling GO:0038001 8.62 CD34 PGR

Sources for Vulvar Dystrophy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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