MCID: VLV026
MIFTS: 21

Vulvar Leiomyosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulvar Leiomyosarcoma

MalaCards integrated aliases for Vulvar Leiomyosarcoma:

Name: Vulvar Leiomyosarcoma 12 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5286
NCIt 50 C40318
UMLS 70 C2168304

Summaries for Vulvar Leiomyosarcoma

Disease Ontology : 12 A vulvar sarcoma that has material basis in smooth muscle cells.

MalaCards based summary : Vulvar Leiomyosarcoma is related to leiomyosarcoma and bartholin's duct cyst. An important gene associated with Vulvar Leiomyosarcoma is CALD1 (Caldesmon 1), and among its related pathways/superpathways is NF-kappaB Signaling. Affiliated tissues include smooth muscle, skin and breast.

Related Diseases for Vulvar Leiomyosarcoma

Diseases related to Vulvar Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)
# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 10.3
2 bartholin's duct cyst 10.1 OCM CALD1
3 myoma 10.1 CD34 CALD1
4 glomangioma 10.1 CD34 CALD1
5 intravascular angioleiomyoma 10.1 CD34 CALD1
6 breast myofibroblastoma 10.1 CD34 CALD1
7 pulmonary vein leiomyosarcoma 10.1 CD34 CALD1
8 glomangiomyoma 10.1 CD34 CALD1
9 angiomyoma 10.1 CD34 CALD1
10 ovarian melanoma 10.1 MLANA CALD1
11 gallbladder leiomyosarcoma 10.1 CD34 CALD1
12 deep leiomyoma 10.1 CD34 CALD1
13 peritoneal benign neoplasm 10.1 CD34 CALD1
14 breast leiomyosarcoma 10.1 CD34 CALD1
15 colon leiomyosarcoma 10.1 CD34 CALD1
16 adult fibrosarcoma 10.1 CD34 CALD1
17 cervical polyp 10.1 CD34 CALD1
18 testicular fibroma 10.1 CD34 CALD1
19 intravenous leiomyomatosis 10.1 CD34 CALD1
20 retroperitoneal leiomyosarcoma 10.1 CD34 CALD1
21 congenital granular cell tumor 10.1 CD34 CALD1
22 uterus perivascular epithelioid cell tumor 10.1 MLANA CALD1
23 perivascular epithelioid cell tumor 10.1 MLANA CALD1
24 cutaneous leiomyosarcoma 10.1 CD34 CALD1
25 subungual glomus tumor 10.1 CD34 CALD1
26 glomus tumor 10.1 CD34 CALD1
27 vaginal endometrial stromal sarcoma 10.1 CD34 CALD1
28 endobronchial leiomyoma 10.1 CD34 CALD1
29 extraosseous osteosarcoma 10.1 CD34 CALD1
30 vulvar benign neoplasm 10.1 OCM CALD1
31 sarcomatous intrahepatic cholangiocarcinoma 10.1 CD34 CALD1
32 angiosarcoma 10.1 MLANA CD34
33 malignant mesenchymoma 10.1 CD34 CALD1
34 liver leiomyosarcoma 10.1 CD34 CALD1
35 lung leiomyosarcoma 10.1 CD34 CALD1
36 bladder leiomyoma 10.1 CD34 CALD1
37 esophagus sarcoma 10.1 CD34 CALD1
38 uterus leiomyosarcoma 10.1 MLANA CALD1
39 penis sarcoma 10.1 MLANA CD34
40 cervical adenosarcoma 10.1 CD34 CALD1
41 conventional fibrosarcoma 10.1 CD34 CALD1
42 benign peritoneal mesothelioma 10.0 CD34 CALD1
43 epidural spinal canal neoplasm 10.0 MLANA CD34
44 myofibroma 10.0 CD34 CALD1
45 hepatic angiomyolipoma 10.0 MLANA CD34
46 sweat gland benign neoplasm 10.0 CD34 CALD1
47 pseudosarcomatous fibromatosis 10.0 CD34 CALD1
48 mixed cell type cancer 10.0 CD34 CALD1
49 infantile myofibromatosis 10.0 CD34 CALD1
50 epithelioid malignant peripheral nerve sheath tumor 10.0 MLANA CD34

Graphical network of the top 20 diseases related to Vulvar Leiomyosarcoma:



Diseases related to Vulvar Leiomyosarcoma

Symptoms & Phenotypes for Vulvar Leiomyosarcoma

Drugs & Therapeutics for Vulvar Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Vulvar Leiomyosarcoma

Genetic Tests for Vulvar Leiomyosarcoma

Anatomical Context for Vulvar Leiomyosarcoma

MalaCards organs/tissues related to Vulvar Leiomyosarcoma:

40
Smooth Muscle, Skin, Breast, Uterus, Spinal Cord, Skeletal Muscle, Small Intestine

Publications for Vulvar Leiomyosarcoma

Articles related to Vulvar Leiomyosarcoma:

(show all 12)
# Title Authors PMID Year
1
Primary vulvar leiomyosarcoma localized in the Bartholin's gland area: A case report and review. 61
33680460 2021
2
Impact of genotypic and phenotypic differences in sarcoma models on the outcome of photochemical internalization (PCI) of bleomycin. 61
28838761 2017
3
Lung Metastasis in a Case of Recurrent Poorly Differentiated Leiomyosarcoma of the Bartholin Gland: A Case Report and Review of the Literature. 61
27158579 2016
4
MMPs and angiogenesis affect the metastatic potential of a human vulvar leiomyosarcoma cell line. 61
26010680 2015
5
Vulvar leiomyosarcoma in Bartholin's gland area: a case report and literature review. 61
18437406 2009
6
Vulvar leiomyosarcoma in a cat. 61
17601762 2007
7
Primary vulvar nocardiosis. 61
17018480 2006
8
Vulvar leiomyosarcoma: a case report in a Nigerian woman. 61
12384866 2002
9
Leiomyosarcoma of the vulva. A case report. 61
11441690 2001
10
Leiomyosarcoma of the vulva: report of a case. 61
8063255 1994
11
Vulvar leiomyosarcoma in pregnancy. 61
2301486 1990
12
Vulvar leiomyosarcoma metastatic to the spinal cord in a dog. 61
632198 1978

Variations for Vulvar Leiomyosarcoma

Expression for Vulvar Leiomyosarcoma

Search GEO for disease gene expression data for Vulvar Leiomyosarcoma.

Pathways for Vulvar Leiomyosarcoma

Pathways related to Vulvar Leiomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.31 MLANA GPX1 CD34

GO Terms for Vulvar Leiomyosarcoma

Sources for Vulvar Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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