MCID: VLV026
MIFTS: 17

Vulvar Leiomyosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulvar Leiomyosarcoma

MalaCards integrated aliases for Vulvar Leiomyosarcoma:

Name: Vulvar Leiomyosarcoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5286
NCIt 50 C40318
UMLS 73 C2168304

Summaries for Vulvar Leiomyosarcoma

MalaCards based summary : Vulvar Leiomyosarcoma is related to leiomyosarcoma and vulvar sarcoma. An important gene associated with Vulvar Leiomyosarcoma is GPX1 (Glutathione Peroxidase 1), and among its related pathways/superpathways is Chromatin Regulation / Acetylation. Affiliated tissues include spinal cord, and related phenotypes are cellular and endocrine/exocrine gland

Related Diseases for Vulvar Leiomyosarcoma

Diseases related to Vulvar Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 10.2
2 vulvar sarcoma 7.6 AR GPX1 H2AFX PTPRC

Symptoms & Phenotypes for Vulvar Leiomyosarcoma

MGI Mouse Phenotypes related to Vulvar Leiomyosarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.71 PTPRC AR GPX1 H2AFX
2 endocrine/exocrine gland MP:0005379 9.62 AR GPX1 H2AFX PTPRC
3 growth/size/body region MP:0005378 9.56 AR GPX1 H2AFX PTPRC
4 digestive/alimentary MP:0005381 9.54 AR GPX1 PTPRC
5 hematopoietic system MP:0005397 9.46 AR GPX1 H2AFX PTPRC
6 immune system MP:0005387 9.26 AR GPX1 H2AFX PTPRC
7 neoplasm MP:0002006 8.8 AR H2AFX PTPRC

Drugs & Therapeutics for Vulvar Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Vulvar Leiomyosarcoma

Genetic Tests for Vulvar Leiomyosarcoma

Anatomical Context for Vulvar Leiomyosarcoma

MalaCards organs/tissues related to Vulvar Leiomyosarcoma:

41
Spinal Cord

Publications for Vulvar Leiomyosarcoma

Articles related to Vulvar Leiomyosarcoma:

# Title Authors Year
1
MMPs and angiogenesis affect the metastatic potential of a human vulvar leiomyosarcoma cell line. ( 26010680 )
2015
2
Vulvar leiomyosarcoma in Bartholin's gland area: a case report and literature review. ( 18437406 )
2009
3
Vulvar leiomyosarcoma in a cat. ( 17601762 )
2007
4
Vulvar leiomyosarcoma: a case report in a Nigerian woman. ( 12384866 )
2002
5
Vulvar leiomyosarcoma in pregnancy. ( 2301486 )
1990
6
Vulvar leiomyosarcoma metastatic to the spinal cord in a dog. ( 632198 )
1978

Variations for Vulvar Leiomyosarcoma

Expression for Vulvar Leiomyosarcoma

Search GEO for disease gene expression data for Vulvar Leiomyosarcoma.

Pathways for Vulvar Leiomyosarcoma

Pathways related to Vulvar Leiomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.03 AR H2AFX

GO Terms for Vulvar Leiomyosarcoma

Cellular components related to Vulvar Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear chromatin GO:0000790 8.62 AR H2AFX

Sources for Vulvar Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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