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MCID: VLV039
MIFTS: 22

Vulvar Seborrheic Keratosis

Categories: Cancer diseases, Reproductive diseases, Skin diseases
Genes Related diseases Publications Pathways
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Aliases & Classifications for Vulvar Seborrheic Keratosis

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MalaCards integrated aliases for Vulvar Seborrheic Keratosis:

Name: Vulvar Seborrheic Keratosis 12 15 17 71
Seborrheic Keratosis of Vulva 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases Skin diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:6944
NCIt 50 C6375
UMLS 71 C1336981
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Summaries for Vulvar Seborrheic Keratosis

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MalaCards based summary : Vulvar Seborrheic Keratosis, also known as seborrheic keratosis of vulva, is related to papilloma and keratosis, seborrheic. An important gene associated with Vulvar Seborrheic Keratosis is TOR1A (Torsin Family 1 Member A), and among its related pathways/superpathways are DNA Damage Response and Human T-cell leukemia virus 1 infection. Related phenotype is muscle.

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Related Diseases for Vulvar Seborrheic Keratosis

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Diseases related to Vulvar Seborrheic Keratosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 80)
# Related Disease Score Top Affiliating Genes
1 papilloma 29.9 PTEN CDKN2A
2 keratosis, seborrheic 10.5
3 keratosis 10.5
4 inverted follicular keratosis 10.5
5 familial episodic pain syndrome 10.1
6 histiocytic sarcoma 9.9 PTEN CDKN2A
7 primary cutaneous b-cell lymphoma 9.9 PTEN CDKN2A
8 adult astrocytic tumour 9.9 PTEN CDKN2A
9 vulvar disease 9.9 PTEN CDKN2A
10 peritoneum cancer 9.9 PTEN CDKN2A
11 acral lentiginous melanoma 9.9 PTEN CDKN2A
12 gliomatosis cerebri 9.9 PTEN CDKN2A
13 penile disease 9.9 PTEN CDKN2A
14 respiratory system benign neoplasm 9.9 PTEN CDKN2A
15 verrucous carcinoma 9.9 PTEN CDKN2A
16 cystic teratoma 9.9 PTEN CDKN2A
17 teratoma 9.9 PTEN CDKN2A
18 ovarian cystadenocarcinoma 9.9 PTEN CDKN2A
19 vulva cancer 9.9 PTEN CDKN2A
20 reproductive organ benign neoplasm 9.9 PTEN CDKN2A
21 uterine corpus cancer 9.9 PTEN CDKN2A
22 oropharynx cancer 9.9 PTEN CDKN2A
23 bilateral breast cancer 9.9 PTEN CDKN2A
24 penile cancer 9.9 PTEN CDKN2A
25 ovary adenocarcinoma 9.9 PTEN CDKN2A
26 pre-malignant neoplasm 9.9 PTEN CDKN2A
27 sporadic breast cancer 9.9 PTEN CDKN2A
28 in situ carcinoma 9.9 PTEN CDKN2A
29 small cell carcinoma 9.9 PTEN CDKN2A
30 neurofibroma 9.9 PTEN CDKN2A
31 endometrial adenocarcinoma 9.9 PTEN CDKN2A
32 cervical adenocarcinoma 9.9 PTEN CDKN2A
33 precursor t-cell acute lymphoblastic leukemia 9.9 PTEN CDKN2A
34 t-cell acute lymphoblastic leukemia 9.9 PTEN CDKN2A
35 carcinosarcoma 9.9 PTEN CDKN2A
36 dedifferentiated liposarcoma 9.9 PTEN CDKN2A
37 liposarcoma 9.9 PTEN CDKN2A
38 suppression of tumorigenicity 12 9.9 PTEN CDKN2A
39 uterine carcinosarcoma 9.9 PTEN CDKN2A
40 infratentorial cancer 9.9 PTEN CDKN2A
41 giant cell glioblastoma 9.9 PTEN CDKN2A
42 tongue disease 9.9 PTEN CDKN2A
43 colorectal adenoma 9.9 PTEN CDKN2A
44 retinal cancer 9.9 PTEN CDKN2A
45 ductal carcinoma in situ 9.9 PTEN CDKN2A
46 small cell cancer of the lung 9.9 PTEN CDKN2A
47 bladder urothelial carcinoma 9.9 PTEN CDKN2A
48 malignant ovarian surface epithelial-stromal neoplasm 9.9 PTEN CDKN2A
49 chordoma 9.9 PTEN CDKN2A
50 ovary epithelial cancer 9.8 PTEN CDKN2A

Graphical network of the top 20 diseases related to Vulvar Seborrheic Keratosis:



Diseases related to Vulvar Seborrheic Keratosis
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Symptoms & Phenotypes for Vulvar Seborrheic Keratosis

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MGI Mouse Phenotypes related to Vulvar Seborrheic Keratosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 8.8 CDKN2A PTEN TOR1A
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Drugs & Therapeutics for Vulvar Seborrheic Keratosis

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Search Clinical Trials , NIH Clinical Center for Vulvar Seborrheic Keratosis

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Genetic Tests for Vulvar Seborrheic Keratosis

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Anatomical Context for Vulvar Seborrheic Keratosis

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Publications for Vulvar Seborrheic Keratosis

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Articles related to Vulvar Seborrheic Keratosis:

# Title Authors PMID Year
1
Vulvar seborrheic keratosis and human papillomavirus. 61
25535982 2015
2
Response to "Vulvar seborrheic keratosis and human papillomavirus". 61
25535983 2015
3
Vulvar seborrheic keratosis: is there a relationship to human papillomavirus? 61
24556611 2014
4
Vulvar seborrheic keratosis. 61
18053380 2007
5
Immunophenotypic and viral (human papillomavirus) correlates of vulvar seborrheic keratosis. 61
12827609 2003
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Variations for Vulvar Seborrheic Keratosis

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Expression for Vulvar Seborrheic Keratosis

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Search GEO for disease gene expression data for Vulvar Seborrheic Keratosis.
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Pathways for Vulvar Seborrheic Keratosis

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Pathways related to Vulvar Seborrheic Keratosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
DNA Damage Response 1
Show member pathways
 11.74 PTEN CDKN2A
2
Human T-cell leukemia virus 1 infection 36
11.66 PTEN CDKN2A
3
Cellular senescence (KEGG) 36
11.45 PTEN CDKN2A
4
DNA Damage Response (only ATM dependent) 1
11.22 PTEN CDKN2A
5
Glioblastoma Multiforme 63
11 PTEN CDKN2A
6
Senescence and Autophagy in Cancer 1
10.65 PTEN CDKN2A
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GO Terms for Vulvar Seborrheic Keratosis

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Biological processes related to Vulvar Seborrheic Keratosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein stabilization GO:0050821 9.32 PTEN CDKN2A
2 neuron projection development GO:0031175 9.26 TOR1A PTEN
3 regulation of protein stability GO:0031647 9.16 PTEN CDKN2A
4 negative regulation of G1/S transition of mitotic cell cycle GO:2000134 8.96 PTEN CDKN2A
5 negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736 8.62 PTEN CDKN2A
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Sources for Vulvar Seborrheic Keratosis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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