MCID: VLV039
MIFTS: 21

Vulvar Seborrheic Keratosis

Categories: Cancer diseases, Reproductive diseases, Skin diseases

Aliases & Classifications for Vulvar Seborrheic Keratosis

MalaCards integrated aliases for Vulvar Seborrheic Keratosis:

Name: Vulvar Seborrheic Keratosis 12 15 73
Seborrheic Keratosis of Vulva 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6944
NCIt 50 C6375
UMLS 73 C1336981

Summaries for Vulvar Seborrheic Keratosis

MalaCards based summary : Vulvar Seborrheic Keratosis, also known as seborrheic keratosis of vulva, is related to keratosis and bartholin's gland disease. An important gene associated with Vulvar Seborrheic Keratosis is MTOR (Mechanistic Target Of Rapamycin Kinase), and among its related pathways/superpathways are Regulation of TP53 Activity and Endometrial cancer. Affiliated tissues include skin, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Vulvar Seborrheic Keratosis

Diseases related to Vulvar Seborrheic Keratosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 keratosis 10.5
2 bartholin's gland disease 9.9 CDKN2A MTOR
3 plasmablastic lymphoma 9.9 CDKN2A MTOR
4 ewing's family of tumors 9.9 CDKN2A MTOR
5 cytomegalovirus infection 9.9 CDKN2A MTOR
6 mantle cell lymphoma 9.9 CDKN2A MTOR
7 glioblastoma multiforme 9.8 CDKN2A MTOR
8 glioblastoma 9.8 CDKN2A MTOR
9 large intestine cancer 9.8 CDKN2A MTOR
10 cervical cancer 9.8 CDKN2A MTOR
11 endometrial cancer 9.8 CDKN2A MTOR
12 pancreatic cancer 9.7 CDKN2A MTOR

Graphical network of the top 20 diseases related to Vulvar Seborrheic Keratosis:



Diseases related to Vulvar Seborrheic Keratosis

Symptoms & Phenotypes for Vulvar Seborrheic Keratosis

GenomeRNAi Phenotypes related to Vulvar Seborrheic Keratosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.62 MTOR
2 Decreased viability GR00221-A-1 9.62 CDKN2A MTOR
3 Decreased viability GR00221-A-3 9.62 CDKN2A
4 Decreased viability GR00221-A-4 9.62 CDKN2A MTOR
5 Decreased viability GR00342-S-1 9.62 MTOR
6 Decreased viability GR00342-S-2 9.62 MTOR
7 Decreased viability GR00402-S-2 9.62 CDKN2A MTOR

Drugs & Therapeutics for Vulvar Seborrheic Keratosis

Search Clinical Trials , NIH Clinical Center for Vulvar Seborrheic Keratosis

Genetic Tests for Vulvar Seborrheic Keratosis

Anatomical Context for Vulvar Seborrheic Keratosis

MalaCards organs/tissues related to Vulvar Seborrheic Keratosis:

41
Skin

Publications for Vulvar Seborrheic Keratosis

Articles related to Vulvar Seborrheic Keratosis:

# Title Authors Year
1
Response to "Vulvar seborrheic keratosis and human papillomavirus". ( 25535983 )
2015
2
Vulvar seborrheic keratosis and human papillomavirus. ( 25535982 )
2015
3
Vulvar seborrheic keratosis: is there a relationship to human papillomavirus? ( 24556611 )
2014
4
Vulvar seborrheic keratosis. ( 18053380 )
2007
5
Immunophenotypic and viral (human papillomavirus) correlates of vulvar seborrheic keratosis. ( 12827609 )
2003

Variations for Vulvar Seborrheic Keratosis

Expression for Vulvar Seborrheic Keratosis

Search GEO for disease gene expression data for Vulvar Seborrheic Keratosis.

Pathways for Vulvar Seborrheic Keratosis

GO Terms for Vulvar Seborrheic Keratosis

Biological processes related to Vulvar Seborrheic Keratosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 8.96 CDKN2A MTOR
2 cell cycle arrest GO:0007050 8.62 CDKN2A MTOR

Molecular functions related to Vulvar Seborrheic Keratosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 8.62 CDKN2A MTOR

Sources for Vulvar Seborrheic Keratosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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