MCID: VLV019
MIFTS: 22

Vulvar Syringoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulvar Syringoma

MalaCards integrated aliases for Vulvar Syringoma:

Name: Vulvar Syringoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:2064
NCIt 50 C40311
UMLS 73 C1520099

Summaries for Vulvar Syringoma

MalaCards based summary : Vulvar Syringoma is related to syringoma and lung leiomyoma. An important gene associated with Vulvar Syringoma is ESR1 (Estrogen Receptor 1), and among its related pathways/superpathways are Cell cycle Role of SCF complex in cell cycle regulation and Signaling by ERBB4.

Related Diseases for Vulvar Syringoma

Diseases related to Vulvar Syringoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 syringoma 10.5
2 lung leiomyoma 9.9 ESR1 PGR
3 vestibular gland benign neoplasm 9.9 ESR1 PGR
4 bartholin's gland adenoma 9.9 ESR1 PGR
5 glassy cell carcinoma of the cervix 9.9 ESR1 PGR
6 vulvar benign neoplasm 9.9 ESR1 PGR
7 trigonitis 9.9 ESR1 PGR
8 vulvar leiomyoma 9.9 ESR1 PGR
9 predominantly cortical thymoma 9.9 ESR1 PGR
10 breast medullary carcinoma 9.9 ESR1 PGR
11 breast scirrhous carcinoma 9.9 ESR1 PGR
12 progesterone resistance 9.9 ESR1 PGR
13 progesterone-receptor positive breast cancer 9.9 ESR1 PGR
14 cribriform carcinoma 9.9 ESR1 PGR
15 oncocytic breast carcinoma 9.9 ESR1 PGR
16 endometrial squamous cell carcinoma 9.9 ESR1 PGR
17 gastric signet ring cell adenocarcinoma 9.9 ESR1 PGR
18 endometrial mucinous adenocarcinoma 9.9 ESR1 PGR
19 adenoid basal cell carcinoma 9.9 ESR1 PGR
20 apocrine adenocarcinoma 9.9 ESR1 PGR
21 gender identity disorder 9.9 ESR1 PGR
22 bartholin's gland benign neoplasm 9.9 ESR1 PGR
23 deep angioma 9.9 ESR1 PGR
24 synchronous bilateral breast carcinoma 9.9 ESR1 PGR
25 breast adenoid cystic carcinoma 9.9 ESR1 PGR
26 cervical carcinosarcoma 9.9 ESR1 PGR
27 estrogen excess 9.9 ESR1 PGR
28 intramuscular hemangioma 9.9 ESR1 PGR
29 glycogen-rich clear cell breast carcinoma 9.9 ESR1 PGR
30 mammographic density 9.9 ESR1 PGR
31 retinitis pigmentosa 47 9.9 ESR1 PGR
32 uterine corpus cancer 9.9 ESR1 PGR
33 adenomyosis 9.9 ESR1 PGR
34 retinitis pigmentosa 20 9.9 ESR1 PGR
35 luminal breast carcinoma 9.9 ESR1 PGR
36 adenosarcoma 9.9 ESR1 PGR
37 cervical clear cell adenocarcinoma 9.9 ESR1 PGR
38 breast benign neoplasm 9.9 ESR1 PGR
39 thoracic benign neoplasm 9.9 ESR1 PGR
40 endometriosis of ovary 9.9 ESR1 PGR
41 inflammatory breast carcinoma 9.9 ESR1 PGR
42 mixed cell type cancer 9.9 ESR1 PGR
43 lipid-rich carcinoma 9.9 ESR1 PGR
44 uterine benign neoplasm 9.9 ESR1 PGR
45 reproductive organ benign neoplasm 9.9 ESR1 PGR
46 smooth muscle tumor 9.9 ESR1 PGR
47 pancreatic mucinous cystadenoma 9.9 ESR1 PGR
48 endometritis 9.8 ESR1 PGR
49 prostatic hypertrophy 9.8 ESR1 PGR
50 peritoneal mesothelioma 9.8 ESR1 PGR

Graphical network of the top 20 diseases related to Vulvar Syringoma:



Diseases related to Vulvar Syringoma

Symptoms & Phenotypes for Vulvar Syringoma

Drugs & Therapeutics for Vulvar Syringoma

Search Clinical Trials , NIH Clinical Center for Vulvar Syringoma

Genetic Tests for Vulvar Syringoma

Anatomical Context for Vulvar Syringoma

Publications for Vulvar Syringoma

Articles related to Vulvar Syringoma:

(show all 12)
# Title Authors Year
1
Vulvar Syringoma in a Postmenopausal Woman: A Case Report. ( 26592076 )
2015
2
Vulvar syringoma: a rare case report. ( 25302203 )
2014
3
Multiple giant vulvar syringoma: an extraordinary report. ( 24340473 )
2013
4
Localized vulvar syringoma causing vulval pruritus and venerophobia. ( 15527439 )
2004
5
Vulvar syringoma aggravated by pregnancy. ( 14530816 )
2003
6
Vulvar syringoma: a clinicopathologic and immunohistologic study of 18 patients and results of treatment. ( 12734503 )
2003
7
Vulvar syringoma, report of a case and review of the literature. ( 12784970 )
2002
8
Vulvar syringoma showing progesterone receptor positivity. ( 10688518 )
2000
9
Vulvar syringoma causing pruritus and carcinophobia: treatment by argon laser. ( 11360416 )
1999
10
Vulvar syringoma exacerbated during pregnancy. ( 8801140 )
1996
11
Localized vulvar syringomas--an unusual cause of pruritus vulvae. ( 8832956 )
1996
12
Vulvar syringoma associated with epidermal cyst. ( 2737815 )
1989

Variations for Vulvar Syringoma

Expression for Vulvar Syringoma

Search GEO for disease gene expression data for Vulvar Syringoma.

Pathways for Vulvar Syringoma

Pathways related to Vulvar Syringoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.4 ESR1 PGR
2
Show member pathways
10.99 ESR1 PGR
3
Show member pathways
10.58 ESR1 PGR

GO Terms for Vulvar Syringoma

Biological processes related to Vulvar Syringoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.16 ESR1 PGR
2 transcription initiation from RNA polymerase II promoter GO:0006367 8.96 ESR1 PGR
3 steroid hormone mediated signaling pathway GO:0043401 8.62 ESR1 PGR

Molecular functions related to Vulvar Syringoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.43 ESR1 PGR
2 enzyme binding GO:0019899 9.4 ESR1 PGR
3 lipid binding GO:0008289 9.37 ESR1 PGR
4 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding GO:0001077 9.32 ESR1 PGR
5 ATPase binding GO:0051117 9.26 ESR1 PGR
6 steroid hormone receptor activity GO:0003707 9.16 ESR1 PGR
7 nuclear receptor activity GO:0004879 8.96 ESR1 PGR
8 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Vulvar Syringoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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