MCID: VLV019
MIFTS: 25

Vulvar Syringoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulvar Syringoma

MalaCards integrated aliases for Vulvar Syringoma:

Name: Vulvar Syringoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:2064
NCIt 51 C40311
UMLS 74 C1520099

Summaries for Vulvar Syringoma

Disease Ontology : 12 A vulvar benign neoplasm that is characterized by the comma (\

MalaCards based summary : Vulvar Syringoma is related to syringoma and malignant syringoma. An important gene associated with Vulvar Syringoma is ESR1 (Estrogen Receptor 1), and among its related pathways/superpathways are Gastric cancer and Cell cycle Role of SCF complex in cell cycle regulation. Affiliated tissues include ovary, cervix and smooth muscle.

Related Diseases for Vulvar Syringoma

Diseases related to Vulvar Syringoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 syringoma 10.7
2 malignant syringoma 10.1
3 vestibular gland benign neoplasm 10.0 ESR1 PGR
4 bartholin's gland adenoma 10.0 ESR1 PGR
5 lung leiomyoma 10.0 ESR1 PGR
6 leiomyoma 10.0 ESR1 PGR
7 myoma 10.0 ESR1 PGR
8 glassy cell carcinoma of the cervix 10.0 ESR1 PGR
9 vulvar benign neoplasm 10.0 ESR1 PGR
10 trigonitis 10.0 ESR1 PGR
11 vulvar leiomyoma 10.0 ESR1 PGR
12 predominantly cortical thymoma 10.0 ESR1 PGR
13 breast medullary carcinoma 10.0 ESR1 PGR
14 breast scirrhous carcinoma 10.0 ESR1 PGR
15 bartholin's gland benign neoplasm 10.0 ESR1 PGR
16 oncocytic breast carcinoma 10.0 ESR1 PGR
17 progesterone-receptor positive breast cancer 10.0 ESR1 PGR
18 progesterone resistance 10.0 ESR1 PGR
19 endometrial squamous cell carcinoma 10.0 ESR1 PGR
20 cribriform carcinoma 10.0 ESR1 PGR
21 endometrial mucinous adenocarcinoma 10.0 ESR1 PGR
22 adenoid basal cell carcinoma 10.0 ESR1 PGR
23 apocrine adenocarcinoma 10.0 ESR1 PGR
24 peritoneal benign neoplasm 9.9 ESR1 PGR
25 gender identity disorder 9.9 ESR1 PGR
26 deep angioma 9.9 ESR1 PGR
27 diffuse peritoneal leiomyomatosis 9.9 ESR1 PGR
28 leiomyomatosis 9.9 ESR1 PGR
29 synchronous bilateral breast carcinoma 9.9 ESR1 PGR
30 breast adenoid cystic carcinoma 9.9 ESR1 PGR
31 female reproductive endometrioid cancer 9.9 ESR1 PGR
32 cervical carcinosarcoma 9.9 ESR1 PGR
33 estrogen excess 9.9 ESR1 PGR
34 intramuscular hemangioma 9.9 ESR1 PGR
35 glycogen-rich clear cell breast carcinoma 9.9 ESR1 PGR
36 mammographic density 9.9 ESR1 PGR
37 cervical clear cell adenocarcinoma 9.9 ESR1 PGR
38 retinitis pigmentosa 47 9.9 ESR1 PGR
39 inflammatory breast carcinoma 9.9 ESR1 PGR
40 retinitis pigmentosa 20 9.9 ESR1 PGR
41 adenosarcoma 9.9 ESR1 PGR
42 luminal breast carcinoma 9.9 ESR1 PGR
43 endometriosis of ovary 9.9 ESR1 PGR
44 endometriosis 9.9 ESR1 PGR
45 breast benign neoplasm 9.9 ESR1 PGR
46 thoracic benign neoplasm 9.9 ESR1 PGR
47 uterine corpus cancer 9.9 ESR1 PGR
48 lipid-rich carcinoma 9.9 ESR1 PGR
49 smooth muscle tumor 9.9 ESR1 PGR
50 uterine benign neoplasm 9.9 ESR1 PGR

Graphical network of the top 20 diseases related to Vulvar Syringoma:



Diseases related to Vulvar Syringoma

Symptoms & Phenotypes for Vulvar Syringoma

Drugs & Therapeutics for Vulvar Syringoma

Search Clinical Trials , NIH Clinical Center for Vulvar Syringoma

Genetic Tests for Vulvar Syringoma

Anatomical Context for Vulvar Syringoma

MalaCards organs/tissues related to Vulvar Syringoma:

42
Ovary, Cervix, Smooth Muscle

Publications for Vulvar Syringoma

Articles related to Vulvar Syringoma:

(show all 11)
# Title Authors Year
1
Vulvar Syringoma in a Postmenopausal Woman: A Case Report. ( 26592076 )
2015
2
Vulvar syringoma: a rare case report. ( 25302203 )
2014
3
Multiple giant vulvar syringoma: an extraordinary report. ( 24340473 )
2013
4
Localized vulvar syringoma causing vulval pruritus and venerophobia. ( 15527439 )
2004
5
Vulvar syringoma aggravated by pregnancy. ( 14530816 )
2003
6
Vulvar syringoma: a clinicopathologic and immunohistologic study of 18 patients and results of treatment. ( 12734503 )
2003
7
Vulvar syringoma, report of a case and review of the literature. ( 12784970 )
2002
8
Vulvar syringoma showing progesterone receptor positivity. ( 10688518 )
2000
9
Vulvar syringoma causing pruritus and carcinophobia: treatment by argon laser. ( 11360416 )
1999
10
Vulvar syringoma exacerbated during pregnancy. ( 8801140 )
1996
11
Vulvar syringoma associated with epidermal cyst. ( 2737815 )
1989

Variations for Vulvar Syringoma

Expression for Vulvar Syringoma

Search GEO for disease gene expression data for Vulvar Syringoma.

Pathways for Vulvar Syringoma

Pathways related to Vulvar Syringoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.92 ESR1 PGR
2
Show member pathways
11.4 ESR1 PGR
3
Show member pathways
10.99 ESR1 PGR
4
Show member pathways
10.58 ESR1 PGR

GO Terms for Vulvar Syringoma

Biological processes related to Vulvar Syringoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.26 ESR1 PGR
2 transcription initiation from RNA polymerase II promoter GO:0006367 8.96 ESR1 PGR
3 transcription, DNA-templated GO:0006351 8.85 ESR1
4 steroid hormone mediated signaling pathway GO:0043401 8.62 ESR1 PGR

Molecular functions related to Vulvar Syringoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.4 ESR1 PGR
2 enzyme binding GO:0019899 9.37 ESR1 PGR
3 lipid binding GO:0008289 9.32 ESR1 PGR
4 ATPase binding GO:0051117 9.26 ESR1 PGR
5 steroid hormone receptor activity GO:0003707 9.16 ESR1 PGR
6 nuclear receptor activity GO:0004879 8.96 ESR1 PGR
7 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Vulvar Syringoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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