MCID: VLV046
MIFTS: 19

Vulvovaginal Gingival Syndrome

Categories: Oral diseases, Rare diseases, Reproductive diseases, Skin diseases

Aliases & Classifications for Vulvovaginal Gingival Syndrome

MalaCards integrated aliases for Vulvovaginal Gingival Syndrome:

Name: Vulvovaginal Gingival Syndrome 58 71

Characteristics:

Orphanet epidemiological data:

58
vulvovaginal gingival syndrome
Inheritance: Not applicable; Age of onset: Adult; Age of death: normal life expectancy;

Classifications:

Orphanet: 58  
Rare gynaecological and obstetric diseases
Rare skin diseases


Summaries for Vulvovaginal Gingival Syndrome

MalaCards based summary : Vulvovaginal Gingival Syndrome is related to lichen planus and oral lichen planus. An important gene associated with Vulvovaginal Gingival Syndrome is HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ Beta 1). Affiliated tissues include skin, and related phenotypes are gingivitis and pruritus

Wikipedia : 74 Lichen planus (LP) is a chronic inflammatory and immune-mediated disease that affects the skin, nails,... more...

Related Diseases for Vulvovaginal Gingival Syndrome

Diseases related to Vulvovaginal Gingival Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 lichen planus 10.5
2 oral lichen planus 10.3
3 mucositis 10.0
4 vulvovaginitis 10.0
5 vulvitis 10.0

Graphical network of the top 20 diseases related to Vulvovaginal Gingival Syndrome:



Diseases related to Vulvovaginal Gingival Syndrome

Symptoms & Phenotypes for Vulvovaginal Gingival Syndrome

Human phenotypes related to Vulvovaginal Gingival Syndrome:

58 31 (show all 13)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 gingivitis 58 31 obligate (100%) Obligate (100%) HP:0000230
2 pruritus 58 31 frequent (33%) Frequent (79-30%) HP:0000989
3 erythema 58 31 frequent (33%) Frequent (79-30%) HP:0010783
4 abnormality of female external genitalia 58 31 frequent (33%) Frequent (79-30%) HP:0000055
5 skin erosion 58 31 frequent (33%) Frequent (79-30%) HP:0200041
6 lichenification 58 31 frequent (33%) Frequent (79-30%) HP:0100725
7 oral ulcer 58 31 frequent (33%) Frequent (79-30%) HP:0000155
8 pain 58 31 frequent (33%) Frequent (79-30%) HP:0012531
9 epidermal acanthosis 58 31 frequent (33%) Frequent (79-30%) HP:0025092
10 parakeratosis 58 31 frequent (33%) Frequent (79-30%) HP:0001036
11 food intolerance 58 31 frequent (33%) Frequent (79-30%) HP:0012537
12 abnormality of tumor necrosis factor secretion 58 31 frequent (33%) Frequent (79-30%) HP:0011118
13 ridged nail 58 31 occasional (7.5%) Occasional (29-5%) HP:0001807

Drugs & Therapeutics for Vulvovaginal Gingival Syndrome

Search Clinical Trials , NIH Clinical Center for Vulvovaginal Gingival Syndrome

Genetic Tests for Vulvovaginal Gingival Syndrome

Anatomical Context for Vulvovaginal Gingival Syndrome

MalaCards organs/tissues related to Vulvovaginal Gingival Syndrome:

40
Skin

Publications for Vulvovaginal Gingival Syndrome

Articles related to Vulvovaginal Gingival Syndrome:

(show all 11)
# Title Authors PMID Year
1
Vulvovaginal-gingival syndrome and esophageal involvement in lichen planus. 61
26585852 2016
2
Syndrome in question. 61
25184936 2014
3
Treatment of recalcitrant vulvovaginal gingival syndrome with adalimumab. 61
21763554 2011
4
Vaginal agglutination: chronic graft-versus-host disease mimics lichen planus. 61
21192182 2011
5
Vulvovaginal-gingival syndrome. 61
20373919 2010
6
Vulvovaginal gingival syndrome and coeliac disease. 61
18624858 2008
7
The vulvovaginal gingival syndrome: a severe subgroup of lichen planus with characteristic clinical features and a novel association with the class II HLA DQB1*0201 allele. 61
16781300 2006
8
Vulvovaginal-gingival syndrome of lichen planus: diagnostic and therapeutic challenge. 61
14717320 2003
9
Lichen planus and the vulvovaginal-gingival syndrome. 61
14584875 2003
10
Erosive oral lichen planus with genital lesions: the vulvovaginal-gingival syndrome and the peno-gingival syndrome. 61
12622271 2003
11
The vulvovaginal-gingival syndrome of lichen planus. The clinical characteristics of 22 patients. 61
7979437 1994

Variations for Vulvovaginal Gingival Syndrome

Expression for Vulvovaginal Gingival Syndrome

Search GEO for disease gene expression data for Vulvovaginal Gingival Syndrome.

Pathways for Vulvovaginal Gingival Syndrome

GO Terms for Vulvovaginal Gingival Syndrome

Sources for Vulvovaginal Gingival Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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